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Our primary goal is to understand the origins of bone forming osteoblasts and bone resorbing osteoclasts, and to discover essential regulatory interactions at the cellular and molecular levels that are responsible for normal skeletal development and function.

Our current research in bone cell biology also interfaces with other systems in both health and disease, for example:

  1. What properties of the osteoblast lineage in the bone marrow are critical for support, engraftment, and survival of long-term hematopoietic stem cells?
  2. How do osteoblasts and osteoclasts facilitate the skeletal metastasis of breast and prostate cancer cells?
  3. Why do mesenchymal stem cells in atherosclerotic plaque differentiate into dysregulated osteoblasts, resulting in pathological vascular calcification?

We invite participation and collaboration in solving these important problems.

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Send RequestIf you do not see the specialty you are looking for, please call us at: 617-355-6000.International visitors should call International Health Services at +1-617-355-5209.
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This department is currently not accepting appointment requests online. Please call us at: 617-355-6000. International +1-617-355-6000.

This department is currently not accepting appointment requests online. Please call us at: 617-355-6000. International +1-617-355-6000.

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The future of pediatrics will be forged by thinking differently, breaking paradigms and joining together in a shared vision of tackling the toughest challenges before us.”
- Sandra L. Fenwick, President and CEO