Information for Healthcare Providers and Researchers

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Overview

Urologic chronic pelvic pain syndrome (UCPPS) is a chronic, debilitating clinical syndrome presenting as pelvic, bladder or suprapubic pain and/or urinary urgency and/or frequency in the absence or any know cause. The etiologic mechanisms underlying UCPPS are poorly understood and although epithelial dysfunction, abnormal mast cell activity, and nerve damage have all been implicated in UCPPS, the importance of each of these factors had not been delineated and is still in dispute.

Our study has previously described a cohort of families in Bulgaria with a high prevalence of UCPPS appearing to be dominantly inherited. We are currently using linkage analysis on these families to identify novel UCPPS loci. Currently we are expanding to collect North American sample cohort from the US and Canada. If you would like to refer a patient please contact us via phone or email-study coordinator Elicia Estrella at e-mail: Elicia.Estrella@childrens.harvard.edu , phone (617) 919-4552

To read more about this study, please visit clinicaltrials.gov or click here.

For a listing of our publications, please click here.
To find these articles online at PubMed, please click here.

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