The Clinical Research Center (CRC) at Boston Children's Hospital is an interdisciplinary, academic and service research center that provides assistance and education to the clinical research community at Children's.
The center directly supports one of Children's core mission areas, to be the leading source of research and discovery, and includes four primary areas of focus:
Clinical research methodology (including biostatistics, epidemiology, and informatics);
Collaboration or consultation on the design, conduct, and analysis of clinical research studies;
Education in clinical research methods and practice; and
The CTSU provides clinical research infrastructure for investigators in the design, initiation, conduct and reporting of clinical research with the goal of translating scientific knowledge into new therapies for pediatric conditions. Funding for the CTSU services is from the Harvard Catalyst which is an affiliate-wide effort to facilitate laboratory-to-bedside translational research and to encourage researcher collaboration.
Within the Clinical Research Center there are four separate but interrelated cores
- Design and Analysis Core;
- Clinical Research Education Core;
- Development and Operations Core; and
- Clinical and Translational Study Unit.
Clinical research is scientific investigation that is conducted with human subjects or on material of human origin such as tissues, specimens, cognitive phenomena or other data for which an investigator directly interacts with human subjects or for which material can be directly linked to an identifiable, living individual. Clinical research includes patient-oriented, community, and population-based research studies.
To be a state-of-the-art, dynamic, and integrated clinical research center that provides leadership, infrastructure, and resources to support patient-oriented studies.
The mission of The Clinical Research Center is to promote excellence and quality in clinical research methods, to encourage best practices in clinical study implementation, and to empower investigators to conduct high quality independent research.
- Scientific Leadership: To provide scientific leadership and expertise on the design, conduct, analysis, and reporting of clinical research studies.
- Education and Training: To provide education, training and mentoring to the clinical researcher community on clinical research methods and study implementation best practices.
- Scientific Collaboration and Consultation: To serve as active scientific collaborators with hospital research initiatives and provide consultation services and/or collaboration in support of the design, conduct, analysis and reporting of clinical research studies.
- Research: To conduct independent research that serves to innovate and advance methodology in statistical design and analysis, survey and data collection methods, electronic data capture methods, and clinical research information technology.
- Integration: To provide a formal interdisciplinary home that links faculty members from the Center with various Departments and Divisions throughout the Hospital.
- Growth: To assist Departments and Divisions throughout the Hospital in recruiting and mentoring faculty members who are engaged in clinical research.
- Professional development: To support the professional development of our faculty and staff so that they may develop their skills and advance their careers,
The Clinical Research Center is committed to ensuring standardized and consistent best practices in clinical research methods, study conduct, data integrity, and the design of ethical protocols for all human subjects.
The Clinical Research Center is committed to providing a positive and motivational work environment that fosters teamwork, mutual respect, integrity, responsiveness and concern for each project, with creative interaction at the interface between areas of science.
The Clinical Research Center is committed to fostering a culture of collaborative, interdisciplinary research of the highest quality, respecting the priorities of each contributing discipline while placing priority on excellence in the joint effort.
Request Services from the CRC
The CRC, CRIT (Clinical Research IT), Research Pharmacy and the Department of Psychiatry (Behavorial Science) offers free one-hour consultations from expert staff. We can help guide and direct you if you have a research question or other general clinical research inquiry.
We can also help if you already know the services that you need from one of our cores (biostatistics, survey methodology, health economics, project management, data or study coordination or access to our patient care unit) and would like to develop a scope of work and budget.
We look forward to working with you! Please click below for either request
Start Request On-line:
Behavioral Science Core
Harvard Catalyst Project Management Services
Subsidized hours for Junior Investigators (Assist. Prof. and below) are now available; guidelines below*:
Project Management Services
(a mix of RN project manager, non-RN project manager, data manager and study coordinator)
1. Junior Investigators eligible, used only once; 150 hrs, up to 1 year
2. Senior investigators (Assoc and Prof) can petition for the subsidized hours one time only.
3. If Project Management hours are allocated, then the number of subsidized coordinator hours decrease to 100 hour
Study Coordinator Hours Only
1. Junior Investigators eligible, used only once; 200 hours up to 1 year
APPLY HERE: catalyst.harvard.edu/services/hccrcrequest/
Note: Data Management Only requests will always be funded by investigator. If paired with a study coordinator or project manager, then the investigator is eligible ; we do not support data entry only requests with study coordinator support
New! Behavorial Science Core
The new core is housed within the Department of Psychiatry Program in Behavioral Science and directed by Deborah Waber, Ph.D. and co-directed by Michelle Bosquet Enlow, Ph.D. The core will provide two kinds of service: behavioral science consultation for investigators who wish to include behavioral outcomes on grants, protocols and manuscripts; and psychometrician services to collect data for protocols that have neuropsychological, psychiatric, psychological or other behavioral outcomes. Click here for billing rates.
New! One-hour consultations
Now you can request a one-hour consultation from Research Pharmacy, CRIT or Behavioral Science experts. CRC one-hour consults are also available. Click on the appropriate link above.
New Billing Plans
Effective March 1, 2012, the Center has implemented new billing plans. Click here for more information. Or click here for a flowchart explaining the billing plans.
The CRC Information Pamphlet
Click here to learn more about the Center in a this easy access guide. Learn about: Who We Are, How to Access Resources, New Billing/Charging Plans, Our Service Menu and Other Resources.
Health Economics Resource
A new Health Economics resource section was launched by the CRC in 2012 under our Design and Analysis Core pages.. The site describes the different types of economic evaluations used by economists and provides useful resources for researchers and policy makers planning to conduct economic evaluations of health care programs and interventions.
Research Practice Guidelines (RPGs)
Learn more about developing randomization procedures, writing a study protocol or useful guidelines for data collection. Click here. See what others are saying…
“I stumbled on to your website Research Practice Guidelines (the power of google). I must say I am very impressed. I have only looked closely at the Guideline for Developing Randomization Procedures, but this is the first time I have seen such a thorough guideline on this subject. Thank you!" Kathy Williams, Biostatistician & Adjunct Professor, University of Ottawa Heart Institute
The CRC Education Core
The CRC Education Core has a new email address: Education Core Be on the look-out for announcements about upcoming courses and events. Click here for a current course list.
Clinical Research Database and Web Survey Technologies Tool
Check out the new Clinical Research Database and Web Survey Technologies Tool. Contact Adam C. Simmons or John Bickel with more questions.