Anesthesiology Research Center

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ACRU Mission Statement

The Anesthesia Clinical Research Unit is committed to supporting the hospital’s mission for world changing research, one study at a time. We strive to be the leading source of research and discovery for anesthesiology, perioperative and pain medicine. Our work is characterized by the joint values of efficiency, ethics, and excellence.

Researchers in the Department of Anesthesiology conduct a variety of basic and clinical investigations in laboratories, ICUs and main operating rooms, and clinical services.

Basic and Clinical research includes studies of:

  • Does Anesthesia Harm the Developing Brain?
  • The Pharmacokinetics of Dexmedetomidine in Children
  • Pediatric Anesthesia NeuroDevelopment Assessment
  • Prospective Evaluation of Intra and Perioperative Anesthesia Ecents/Complications in Infants with Craniosynostosis Undergoing Endoscopic Cranial Suture Removal
  • Multicenter Study of Use and Complications in Pediatric Regional Anesthesia
  • Pharmacokinetics of Tranexamic Acid (TXA) in Children Undergoing Repair of Congenital Heart Defects Utlizing Cardiopulmonary Bypass
  • Masimo Blue Sensor Validation Study
  • Efficacy and Safety of Local Anesthetic Infusion with Ropivacaine for the Management of Pain after Surgical Correction of Uteropelvic Junction Stenosis
  • Comparing Safety and Efficacy of Dexmedetomidine and Propofol in Patients Requiring Sedation for MRI Scanning
  • Assessing the Cortical Response to External Stimuli in Anesthetized Subjects Using Near Infared Spectroscopy
  • A Comparitive Case Control Study of Pediatric Patients Transferred to a Higher Level of Care with Signs of Shock
  • Surveying Parental Motivation for Enrolling or Declining Participation in Pediatric Anesthesia Clinical Research: An Assessment of Randomized and Non-Randomized Clinical Studies

Featured researchers in the Department of Anesthesiology hold faculty appointments at Harvard Medical School.

Latest Research in Anesthesiology

Dusica Bajic, MD, PhD Anesthesiology, Opioid tolerance
Charles Berde, MD, PhD Pain management
Kathryn Commons, PhD Neuroscience
Douglas Cowan, PhD Cardiovascular biology
Amy Durall, MD Clinician and Parental Attitudes Regarding Advanced Care Planning, Resuscitation Status, Do Not Resu
Paul Hickey, MD Anesthesia in cardiac surgery
Monica E. Kleinman, MD Farnesyltransferase inhibitors in children with proge
Daniel S. Kohane, MD, PhD Pain, Peritoneal and other adhesions, Intracranial drug delivery, Microfluidics, Tissue engineering
Nilesh Mehta, MD Nutritional and Metabolic Aspects of Critical Illness in Children
Gregory Priebe, MD Pseudomonas aeruginosa infections
Adrienne Randolph, MD, MSc Outcomes in ICU
Rana Sharara-Chami Effects of the Stress Hormone Epinephrine
Robert D. Troug Informed Consent,organ transplantation,medical futility,rationing stem cell research,end-of-life car
Gerhard K. Wolf, MD Novel modes of ventilation in pediatric respiratory failure, means of assessing lung volume
Grace Yoon, APN, MSN, NNP Supports research activities for fellows and faculty staff
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The future of pediatrics will be forged by thinking differently, breaking paradigms and joining together in a shared vision of tackling the toughest challenges before us.”
- Sandra L. Fenwick, President and CEO