Angiogenesis (Related links)

For more information on Dr. Folkman and discoveries made in his lab:

Children's Web site

Judah Folkman, MD, Research Home Page

Folkman Laboratory Web site

Selected Media Coverage

Once-Touted Drug for Cancer Finds New Life in China - Wall Street Journal, December 22, 2005

The Anti-Cancer Strategist - Business Week, Jun 6, 2005

Inside Judah Folkman's Lab - Business Week online extra, Jun 6, 2005

Early Warning: New Way to Find Cancer Earlier - Wall Street Journal, Dec 7, 2004 [Angiogenic compounds as cancer biomarkers]

Cancer Warrior - PBS NOVA (2001, WGBH Educational Foundation; filmed during 2000)

Articles Available Online

2007
Angiogenesis: An Organizing Principle for Drug Discovery? - Nature Reviews Drug Discovery, April 2007 [review article by Judah Folkman, MD]

2006
Rising star: The Unlikely Journey of a Revolutionary Cancer Drug - Dream Magazine, Spring 2006 [Endostatin]

Anti-Cancer Technologies Licensed to Genentech - online update

2005
Urine Test May Help Monitor Disfiguring Birthmarks - Pediatric Views, Aug 2005 [Markers of angiogenesis may predict aggressiveness of a vascular anomaly - Marsha Moses, PhD]

Blood Vessel Drugs Halt Cancer Growth - Harvard Gazette, Jul 21, 2005 [Endostatin, Avastin, doxycycline, Celebrex]

A Dipstick Test for Breast Cancer? - Dream Magazine, Spring 2005 [Biomarkers in urine may predict the angiogenic switch - Marsha Moses, PhD]

2004
Breast cancer, Angiogenesis and the Mammography paradox - Children's News, Dec 1, 2004 [Michael Retsky, PhD in the Folkman lab proposes that surgery to remove a primary breast tumor may trigger angiogenesis and relapse]

From Infamy to Therapy: How the most reviled drug in history became a cancer treatment - Children's News, Oct 4, 2004 [Development of thalidomide as a cancer treatment - Robert D'Amato, MD, PhD]

Angiogenesis Inhibitors Revived, Revealed in Progress Against Cancer - Harvard Focus, Mar 19, 2004 [Reformulation of TNP-470 - Ronit Satchi-Fainaro, PhD]

Cancer Drug Given New Life - Harvard Gazette, Feb 26, 2004 [Reformulation of TNP-470 - Ronit Satchi-Fainaro, PhD]

2003
Pigment Tied to Blindness, Cancer - Harvard Gazette, Feb 6, 2003 [Racial differences in angiogenesis - Robert D'Amato, MD, PhD]

A Relentless Attack on Tumor's Blood Supply - Research Notes, Dana-Farber Cancer Institute, Summer/Fall 2003 [A trial of Avastin plus low-dose chemotherapy starts at Dana-Farber]

2002
In Lab, Fat Mice Slim Down - Children's News, Aug 30, 2002 [Angiogenesis inhibitors could curb obesity - Maria Rupnick, MD, PhD]

1990s
Studies Find Cancer Drugs May Double As Heart Savers - Harvard Gazette, Apr 29, 1999 [Angiogenesis inhibitors inhibit atherosclerosis - Karen Moulton, MD; others use angiogenic compounds to grow collateral vessels after heart attack]

New Drug Drastically Reduces Cancer Tumors - Harvard Gazette, Feb 13, 1997 [Discovery of endostatin]

Press Releases

New Approaches to Endometriosis Treatment: Mouse Experiments Point the Way - Jul 3, 2007

Why Are African American Women More Likely than Whites to Die From Breast Cancer? - Feb 21, 2007

Dr. Judah Folkman Reports Finding of Panel of Biomarkers in Platelets in Mice that May Permit Early Diagnosis of Cancer or Cancer Recurrence - Mar 27, 2006

Does Surgery Induce Angiogenesis in Dormant Breast Cancer? Possible explanation for the "mammography paradox" in women aged 40-49 - Sep 12, 2005

Urine Test May Help Monitor Disfiguring Birthmarks: Study raises hope of treating aggressive vascular malformations with anti-angiogenesis drugs - Jul 5, 2005

A More Accurate Screening Test for Prostate Cancer? Angiogenesis marker in urine may improve on PSA testing, reduce unnecessary biopsies - Feb 16, 2005

Many Have "Cancer," But Few Progress to True Disease: Natural Angiogenesis Inhibitors May Lead to Next Wave of Protective Drugs - Feb 25, 2004 [essay in Nature]

Fat Tissue Can Be Controlled by the Blood Vessels that Feed It: Weight loss and maintenance in mice achieved with angiogenesis inhibitors - Aug 5, 2002