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Long regarded as one of the nation's leading stem cell researchers, Daley focuses on the use of human embryonic stem cells to replace problematic genes that lead to diseases such as sickle cell anemia. The use of human embryonic stem cells would make it unnecessary for children with cancers and diseases of the blood system to rely on hard-to-find bone marrow donors. The Children's stem cell research team is working on developing new lines of embryonic stem cells that are unique to each patient and can be used to repair defective genes throughout the body.
Daley has also done extensive research on chronic myeloid leukemia (CML), a cancer of the blood caused by genetically defective stem cells. His findings of a specific protein causing CML led to the development of Gleevac, a highly effective drug for treating CML.
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