Innovation

Translating research from the lab dish to patient applications requires a deep, multi-dimensional commitment to collaboration. Boston Children’s partners with clinicians and researchers, private industry and venture capitalists across the globe to ensure that transformative innovations reach those who matter most: children.

Our Technology Innovation & Development Office (TIDO) has seen sponsored research and collaborations triple from nine in 2009 to 29 in 2013, addressing needs as diverse as treating rare diseases like myotubular myopathy to improving communication for children with autism.

Connect with us today via email alerts, OPENPediatricsTM  our blog Vector, @BCH_Innovation on Twitter, or visit with us at upcoming events, like Arab Health and Taking on Tomorrow

Breakthroughs

Boston Children’s culture of innovation and collaboration provide the essential infrastructure to deliver breakthroughs that transform pediatric patient care and enable us to close the loop from bench to bedside, like:

Bio-inspired glue

January 8, 2014—For decades, surgeons have needed a safe and effective adhesive that can be used internally in the body. Researchers from Boston Children’s Hospital, Brigham and Women’s Hospital and the Massachusetts Institute of Technology have developed a nontoxic, biologically inspired adhesive that can rapidly attach biodegradable patches inside a beating heart—in the exact place where the hole occurs, such as with ventricular heart defects. Learn more about bio-inspired glue, Chief of Cardiac Surgery, Pedro del Nido, MD, or read about the clinical adhesive in a recent Boston Magazine piece.

Gene therapy

Dec. 7, 2013—Eight of nine boys with X-linked severe combined immunodeficiency syndrome (SCID-X1), a fatal genetic immunodeficiency also known as “bubble boy” disease, who were treated as part of an international clinical study of a new form of gene therapy, are doing well, with functioning immune systems and free of infections associated with SCID-X1, between nine and 36 months following treatment, according to Sung-Yun Pai, MD, a pediatric hematologist-oncologist from Dana-Farber/Boston Children's Cancer and Blood Disorders Center. Learn more about gene therapy. 

Split liver transplants

June 10, 2013—Data, collected and analyzed by a team led by Boston Children's Hospital researchers, demonstrated split liver transplants—with the smaller portion going to a young child and the larger to an adult—the smaller portion used for the child will last just as long as if the child had received a whole organ from a donor close to his size. Read our press release announcing the study or view a recent article published by Boston Globe.

Learning Exchange

OPENPediatricsTM: Taking social learning to the global level

Boston Children’s Hospital and IBM have partnered to develop OPENPediatricsTM, an interactive digital learning platform that promotes knowledge sharing about the care of critically ill children by providing doctors and nurses across the globe access to colleagues and vital information.

Clinicians in more than 80 countries use OPENPediatrics to inform and improve pediatric care delivery.

The peer reviewed, open-source, not-for-profit platform makes information available at no cost to anyone, anywhere, at any time.

The program features a Global Community for knowledge exchange, Guided Learning Pathways that provide advanced training in specific subspecialties and a Content Library with videos, tools and summaries.

Learn more about OPENPediatrics at the Boston Children’s booth #5A29 during Arab Health 2014.

Visit Us at Arab Health

January 26-29, 2014 

Booth 5A29

Meet Boston’s Children’s Hospital doctors participating in this year’s Arab Health conference or stop by for a demonstration of OPENPediatricsTM.

Jointly developed by Boston Children’s and IBM, OPENPediatrics provides a digital learning platform designed to promote knowledge sharing and improve care of critically ill children across the globe.

Contact us before, during, and after the event:

•   EMAIL:  international.resources@childrens.harvard.edu
•   URL: www.bostonchildrens.org/arabhealth

Meet our Team at Arab Health: 

•   Martha Fishman, MD, co-director of the Interstitial Lung Disease Program, presents on interstitial lung disease Jan. 27, 10:00-11:10 a.m.

•   Jesse Esch, MD, pediatric interventional cardiologist, shares the latest developments in catheter interventions in congenital cardiology Jan. 27, 4:00-4:30 p.m.

•   Jon Vanderhoof, MD, pediatric gastroenterologist, presents on allergic disorders of the GI tract in children Jan. 28, 10:00-10:30 a.m.

•   Caleb Nelson, MD, assistant in urology, shares advances in pediatric nephrolithiasis Jan. 27, 11:45 a.m-12:15 p.m., and radiation exposure reduction in urologic patients Jan. 27, 12:15 pm.-12:45 p.m.

•   Alan Retik, MD, senior associate in urology, reviews bladder exstrophy: contemporary care at Boston Children’s Hospital Jan. 27, 12:45 p.m. to 1:15 p.m.

Stay in touch with Boston Children’s Hospital

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Find & Follow Us: Vector blog, @BCH_Innovation on Twitter

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Join Us at Taking on Tomorrow

Global Innovation Summit | October 30-31, 2014  | Boston, USA  
Taking on Tomorrow, Boston Children’s Hospital second annual Pediatric Innovation Summit + Awards, will bring together thought leaders and stakeholders from the entire spectrum of global pediatric health care with a single goal: to foster partnerships that accelerate solutions for pediatric care from idea to market. The focus is transformative care. Our comprehensive agenda promises to engage attendees, panelists and the audience in: cancers genomics, predictive analytics and big data, rare diseases pathways, innovation acceleration, top challenges and opportunities for CEOs and mobile and telehealth in pediatrics.MORE

About Us

Boston Children's is home to the world's largest and most active pediatric research enterprise. From the laboratory to the bedside, every member of our staff uniquely understands that their work directly affects children everywhere—in our exam rooms, surgical suites and other care settings worldwide. Our partnerships with clinicians and researchers, private industry and venture capitalists across the globe helps us fulfill our ultimate mission of ensuring that transformative innovations know no limitations and can reach those who matter most: children. 

Since opening our doors in 1869, our physicians have:

•   achieved the first partial remission of acute leukemia
•   performed the first pediatric heart transplant
•   launched the Advanced Fetal Care Center
•   built partnerships with hospitals and providers across the globe 

Today, this culture of innovation, coupled with our commitment to improving outcomes, drives our research agenda. Take, for example, Ofer Levy’s, MD, PhD, of the Division of Infectious Diseases, mission to protect newborns from infection like whooping cough and pneumonia could lead to the development of a compound that makes vaccines effective at birth. This could extend protection to millions of children in the developing world, whose access to a health care provider is limited to birth. Martha Murray, MD, orthopedic surgeon, whose two-decade quest to minimize arthritis risk for patients undergoing anterior cruciate ligament (ACL) reconstruction, which approaches 80 percent, led to the development of a bio-engineered scaffold saturated with the patient’s own blood to stimulate healing.MORE