Clinical Spotlight

LIke ThisLIke ThisLIke ThisLIke ThisLIke This

A coordinated, collaborative approach to maternal fetal medicine

Collaboration is the key to the success of the Cardiovascular Disease and Pregnancy Program. A joint effort of Boston Children’s and Brigham and Women’s Hospital, the program offers a coordinated approach to maternal fetal medicine, bringing together a team of cardiologists, obstetricians, anesthesiologists and researchers. The program is directed by Boston Children’s Hospital’s Anne Marie Valente, MD, along with obstetrician Katherine Economy, MD, and cardiologist Rena Pande, MD.

On the clinical side, the program cares for women with congenital and other pre-existing heart and vascular diseases or cardiovascular conditions arising during pregnancy. The program also has strong education and research components that Valente hopes will help guide practitioners in caring for pregnant women with heart conditions.

The program was created in response to the high volume of women with heart conditions who were interested in pregnancy and are cared for by the Boston Adult Congenital Heart (BACH) and Pulmonary Hypertension Service. Valente states that “when girls were born with heart disease decades ago, their parents were often instructed to limit their physical activity or that pregnancy would not be in their future.” However, many women with congenital heart disease are choosing to undergo pregnancies because of advances that have been made in the treatment of congenital heart conditions, as well as our increased knowledge of the hemo­dynamic changes during pregnancy. “Our knowledge of the impact of heart conditions on pregnant women has changed, making pregnancy more viable and manageable,” Valente says.

To care for this growing group of women, BACH needed “an organized process.” Managing that process is the mission of the Cardiovascular Disease and Pregnancy Program.

Valente and her colleagues participate in a weekly clinic at Brigham and Women’s Hospital and see women with heart conditions on the same day as Dr. Economy’s team. There is a monthly conference, coordinated by Nancy Bark­er, PA-C, of Boston Children’s, to review each patient and make delivery plans on a case by case basis. Valente explains that “some women who are at higher risk for a cardiac complication during pregnancy need a plan—how much fluid to give, what kinds of medicines they need, and, if they need to go in for an (emergency) procedure, how best to execute this plan.” This weekly conference is attended by members of the maternal fetal medicine team, obstetrical anesthesia team, under the direction of Jean Marie Carabuena, MD, and the BACH clinicians, under the leadership of Michael J. Landzberg, MD. The weekly Cardiovascular Disease and Pregnancy clinic is also staffed by other BACH team members, including Michael Singh, MD who directs the care of women with connective tissue disorders and Caitlyn Joyce, PA-C.

Along with planning and care, Valente says that “part of our role is to educate the community and the families.” Women need to know that, despite advances, “there is absolute risk for complications because of the huge hemodynamic load on the body for the nine months of pregnancy and in the post-partum period.” Also, women need to know that, through the Cardiovascular Disease and Pregnancy Program, “there’s a coordinated team here to help them, a team that works directly with their obstetrician and is available at all times.”

Building on the clinical and educational work is the program’s research effort. With funding from a Watkins Discovery Award in Cardiovascular Medicine from Brigham and Women’s, the Cardiovas­cular Disease and Pregnancy Program is in the second year of a research initiative called STORCC (standardizing outcomes in reproductive cardiovascular care). According to Valente, STORCC is currently collecting data on more than 100 women who are at different stages of pregnancy. Women in the program are asked to fill out questionnaires about their pregnancy and their post-partum experiences. The research coordinators for this project, Amy Harmon, BA, and Jenna Schreier, BA, work closely with the cardiology and obstetrical teams.

Based on the experience of the past few decades, Valente says that “we know that many women with heart conditions are living active, functional lives... Some may have complications or issues,” she concedes, “but that does not necessarily mean that they can’t undergo pregnan­cy.” Through STORCC, “we’re looking at exercise tolerance and certain imaging parameters, but not getting hung up on the fact that they had a heart condition when they were little,” Valente states.

Previous studies done on pregnant women with heart conditions are “largely retrospective and report up to a 20% chance of maternal complications,” Valente says. With STORCC, more contemporary information will be available to guide care. Preliminary results of the STORCC study will be prepared in June.

Research, education and the coordination of care between different institutions and specialties should lead to better outcomes for patients, Valente believes. “The field of maternal fetal medicine is a field that we, as cardiologists, often don’t think about,” she says. “For example, many cardiologists don’t necessarily discuss contraceptive or reproductive counseling with woman of childbearing age, which may be a missed opportunity.”

Valente has high praise and high hopes for the Cardiovascular Disease and Preg­nancy Program. “It’s been a very reward­ing experience for us to work with obstetricians, anesthesiologists and oth­ers who care for pregnant women with heart conditions,” Valente asserts. “It would not be possible without the support of the BACH administrators, Lauren Serge and Samantha Buechner, who work very hard to ensure that patients are seen in a coordinated, timely fashion. It hasn’t been easy to do, but thanks to a great team of committed provider, it's been enormously successful."

We are grateful to have been ranked #1 on U.S. News & World Report's list of the best children's hospitals in the nation for the third year in a row, an honor we could not have achieved without the patients and families who inspire us to do our very best for them. Thanks to you, Boston Children's is a place where we can write the greatest children's stories ever told.”
- Sandra L. Fenwick, President and CEO

Boston Children's Hospital
300 Longwood Avenue, Boston, MA 02115
For Patients: 617-355-6000
For Referring Providers: 844-BCH-PEDS | 844-224-7337