What is the treatment for TTTS?
There are several different procedures used to treat TTTS. Which procedure or combination of procedures is used will usually depend on the level of severity of the condition.
Some cases of TTTS never progress past the earliest stages, when there is still urine in the bladder of the donor twin, who never becomes "stuck." These cases would require only close monitoring to ensure that the condition does not progress.
Once the condition progresses, your doctor may advise you to undergo any of the following procedures, all of which are designed to alleviate harmful symptoms until the time of delivery, when the twins no longer need to share a placenta.
- Serial amniocentesis - A procedure that is used periodically to relieve the recipient twin of the excess accumulation of amniotic fluid. For this procedure, a needle is used to enter the mother's uterus and the recipient twin's amniotic sac, which is drained of fluid.
- Amniotic septostomy - A procedure in which a needle is inserted into the mother's abdomen, and the membrane between the two twins is punctured to allow equilibration of amniotic fluid between the two sacs, giving the smaller fetus more amniotic fluid.
- Umbilical cord ligation (tying of the umbilical cord) - This surgery is performed endoscopically (through a small puncture in the mother's abdomen) when one twin is severely compromised with impending death.
- If one twin dies the other is at high risk for neurological damage caused by a severe drop in blood pressure. The procedure should offset the drop in blood pressure and prevent other continued symptoms in the surviving twin.
- Endoscopic laser surgery is a procedure in which a small puncture is made on the mother's abdomen and endoscope is inserted into the amniotic cavity. This allows the surgeon to look into the uterus and use a laser to interrupt abnormal connections between the twins.
How will my babies be after the procedure?
That depends on the how severe the condition is and how far it's progressed.
Some studies have shown, however, that twin fetuses with advanced TTTS have a better survival rate after undergoing either amniotic septostomy or endoscopic laser surgery than those who undergo the other treatments discussed above.
Approximately 80 percent of fetuses with TTTS will die if there is no treatment at all. When one fetus dies, there is a high incidence of brain injury to the other fetus.
With umbilical cord ligation, brain injury might be prevented in the surviving twin.
Some survivors may do well and be completely healthy, while others may have injuries to their hearts and kidneys. There is also a risk of preterm delivery after any of these procedures.
| Children's Advance Fetal Care Center |
"Looking at them now, it's hard to remember all we went through," says Stephanie Villers about her two twin boys. Stephanie was diagnosed with TTTS and treated by the experts at our Advanced Fetal Care Center. To read more about her inspiring story, click here.