Large cell lymphoma is a type of non-Hodgkin lymphoma. It’s a cancer in the lymphatic system, which is part of the immune system, which works to fight disease and infections. Large cell lymphoma may develop in the lymph system tissue in the neck, chest, throat or abdomen.
- It can spread to the skin or tissues under the skin. It may also spread to bone marrow and the brain.
- It’s thought to be caused by genetics and/or exposure to viral infections, radiation or chemotherapy.
- It accounts for about 30 percent of non-Hodgkin lymphomas in children.
- It’s more common in Caucasian boys.
- Treatments may involve a combination of therapies including surgery, radiation, chemotherapy and/or stem-cell transplants.
How Dana-Farber/Boston Children’s approaches large cell lymphoma
Patients with large cell lymphoma are treated through Dana-Farber/Boston Children's Cancer and Blood Disorders Center, an integrated pediatric hematology and oncology partnership between Dana-Farber Cancer Institute and Boston Children’s Hospital. Specialists from Boston Children’s Hospital work very closely with the experts at Dana-Farber Cancer Institute to ensure that every aspect of your child’s health is overseen before, during and after his treatment period. Members of Lymphoma Program —specialists in oncology, radiation oncology, surgery, interventional and diagnostic radiology and hematopathology—have specialized expertise in pediatric lymphomas.