Langerhans cell histiocytosis (LCH) is a rare disorder that occurs when your child has too many of a certain type of white blood cell.
- The white blood cell affected is called a Langerhans cell (it was named for a German scientist).
- These cells normally reside in the skin and help fight infections and destroy certain foreign substances in the body.
- In LCH, these cells accumulate on bones and other parts of the body, particularly the head and neck, causing a wide range of problems.
- LCH can also be found in the ribs, sternum, long bones of the arms and legs, vertebra of the spine and the pelvis.
- Although LCH can occur in people of all ages, a majority of cases occur in children who are under 10 years old.
Individualized care, new treatments
Through Dana-Farber/Boston Children’s Cancer and Blood Disorders Center, a 50-year partnership between Dana-Farber Cancer Institute and Boston Children's Hospital, patients with LCH receive individualized care to treat every aspect of this condition from an expert team of specialists. Patients also benefit from a team of researchers striving to understand the scientific causes of Langerhans cell histiocytosis, which results in continual introduction of new treatment options.