Time-buie-md

Timothy Buie, MD

Attending Physician

Assistant Professor of Pediatrics, Harvard Medical School

    Contact: 617-355-6058

Medical Services

Specialties

  • Gastrointestinal Care of Children with Special Needs

Departments

  • Gastroenterology, Hepatology and Nutrition

Languages

  • English
To schedule an appointment: Call 617-355-6058
Time-buie-md

 

Philosophy of Care

        It became clear that children with developmental problems were often suffering physical distress that they were unable to verbalize and problem behaviors often seen in these children were, at times, set off by medical issues. I have focused on the care of these children for over 20 years as well as expanding education about these issues in the medical community.

Experience and Education

Education

Fellowship

Yale Medical School, 1990

New Haven, Connecticut

Medical School

University of Missouri at Kansas City, 1984

Kansas City, Missouri

Residency

Bridgeport Hospital, 1988

Bridgeport, Connecticut

Certifications

  • Pediatric Gastroenterology

Professional History

I am a general pediatric gastroenterologist focused on the care of children with autism and developmental problems. These problems include similar problems seen in general pediatric GI care but recognizing these problems in children with developmental problems is often difficult. This has been my focus.

Publications

Publications powered by Harvard Catalyst Profiles
  1. Fiorentino M, Sapone A, Senger S, Camhi SS, Kadzielski SM, Buie TM, Kelly DL, Cascella N, Fasano A. Blood-brain barrier and intestinal epithelial barrier alterations in autism spectrum disorders. Mol Autism. 2016; 7:49.
  2. Kushak RI, Winter HS, Buie TM, Cox SB, Phillips CD, Ward NL. Analysis of the Duodenal Microbiome in Autistic Individuals: Association with Carbohydrate Digestion. J Pediatr Gastroenterol Nutr. 2016 Nov 02.
  3. Kushak RI, Buie TM, Murray KF, Newburg DS, Chen C, Nestoridi E, Winter HS. Evaluation of Intestinal Function in Children With Autism and Gastrointestinal Symptoms. J Pediatr Gastroenterol Nutr. 2016 May; 62(5):687-91.
  4. Zwaigenbaum L, Bauman ML, Stone WL, Yirmiya N, Estes A, Hansen RL, McPartland JC, Natowicz MR, Choueiri R, Fein D, Kasari C, Pierce K, Buie T, Carter A, Davis PA, Granpeesheh D, Mailloux Z, Newschaffer C, Robins D, Roley SS, Wagner S, Wetherby A. Early Identification of Autism Spectrum Disorder: Recommendations for Practice and Research. Pediatrics. 2015 Oct; 136 Suppl 1:S10-40.
  5. Zwaigenbaum L, Bauman ML, Fein D, Pierce K, Buie T, Davis PA, Newschaffer C, Robins DL, Wetherby A, Choueiri R, Kasari C, Stone WL, Yirmiya N, Estes A, Hansen RL, McPartland JC, Natowicz MR, Carter A, Granpeesheh D, Mailloux Z, Smith Roley S, Wagner S. Early Screening of Autism Spectrum Disorder: Recommendations for Practice and Research. Pediatrics. 2015 Oct; 136 Suppl 1:S41-59.
  6. Zwaigenbaum L, Bauman ML, Choueiri R, Fein D, Kasari C, Pierce K, Stone WL, Yirmiya N, Estes A, Hansen RL, McPartland JC, Natowicz MR, Buie T, Carter A, Davis PA, Granpeesheh D, Mailloux Z, Newschaffer C, Robins D, Smith Roley S, Wagner S, Wetherby A. Early Identification and Interventions for Autism Spectrum Disorder: Executive Summary. Pediatrics. 2015 Oct; 136 Suppl 1:S1-9.
  7. Zwaigenbaum L, Bauman ML, Choueiri R, Kasari C, Carter A, Granpeesheh D, Mailloux Z, Smith Roley S, Wagner S, Fein D, Pierce K, Buie T, Davis PA, Newschaffer C, Robins D, Wetherby A, Stone WL, Yirmiya N, Estes A, Hansen RL, McPartland JC, Natowicz MR. Early Intervention for Children With Autism Spectrum Disorder Under 3 Years of Age: Recommendations for Practice and Research. Pediatrics. 2015 Oct; 136 Suppl 1:S60-81.
  8. Buie T. Potential Etiologic Factors of Microbiome Disruption in Autism. Clin Ther. 2015 May 01; 37(5):976-83.
  9. Buie T. The relationship of autism and gluten. Clin Ther. 2013 May; 35(5):578-83.
  10. Williams BL, Hornig M, Buie T, Bauman ML, Cho Paik M, Wick I, Bennett A, Jabado O, Hirschberg DL, Lipkin WI. Impaired carbohydrate digestion and transport and mucosal dysbiosis in the intestines of children with autism and gastrointestinal disturbances. PLoS One. 2011; 6(9):e24585.
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  12. Kushak RI, Lauwers GY, Winter HS, Buie TM. Intestinal disaccharidase activity in patients with autism: effect of age, gender, and intestinal inflammation. Autism. 2011 May; 15(3):285-94.
  13. Buie T, Fuchs GJ, Furuta GT, Kooros K, Levy J, Lewis JD, Wershil BK, Winter H. Recommendations for evaluation and treatment of common gastrointestinal problems in children with ASDs. Pediatrics. 2010 Jan; 125 Suppl 1:S19-29.
  14. Buie T, Campbell DB, Fuchs GJ, Furuta GT, Levy J, Vandewater J, Whitaker AH, Atkins D, Bauman ML, Beaudet AL, Carr EG, Gershon MD, Hyman SL, Jirapinyo P, Jyonouchi H, Kooros K, Kushak R, Levitt P, Levy SE, Lewis JD, Murray KF, Natowicz MR, Sabra A, Wershil BK, Weston SC, Zeltzer L, Winter H. Evaluation, diagnosis, and treatment of gastrointestinal disorders in individuals with ASDs: a consensus report. Pediatrics. 2010 Jan; 125 Suppl 1:S1-18.
  15. Campbell DB, Buie TM, Winter H, Bauman M, Sutcliffe JS, Perrin JM, Levitt P. Distinct genetic risk based on association of MET in families with co-occurring autism and gastrointestinal conditions. Pediatrics. 2009 Mar; 123(3):1018-24.
  16. Hornig M, Briese T, Buie T, Bauman ML, Lauwers G, Siemetzki U, Hummel K, Rota PA, Bellini WJ, O'Leary JJ, Sheils O, Alden E, Pickering L, Lipkin WI. Lack of association between measles virus vaccine and autism with enteropathy: a case-control study. PLoS One. 2008 Sep 04; 3(9):e3140.
  17. Nanthakumar NN, Young C, Ko JS, Meng D, Chen J, Buie T, Walker WA. Glucocorticoid responsiveness in developing human intestine: possible role in prevention of necrotizing enterocolitis. Am J Physiol Gastrointest Liver Physiol. 2005 Jan; 288(1):G85-92.
  18. Chitkara DK, Nurko S, Shoffner JM, Buie T, Flores A. Abnormalities in gastrointestinal motility are associated with diseases of oxidative phosphorylation in children. Am J Gastroenterol. 2003 Apr; 98(4):871-7.
  19. Biller JA, Katz AJ, Flores AF, Buie TM, Gorbach SL. Treatment of recurrent Clostridium difficile colitis with Lactobacillus GG. J Pediatr Gastroenterol Nutr. 1995 Aug; 21(2):224-6.
  20. Di Lorenzo C, Flores AF, Buie T, Hyman PE. Intestinal motility and jejunal feeding in children with chronic intestinal pseudo-obstruction. Gastroenterology. 1995 May; 108(5):1379-85.
  21. Gryboski JD, Buie T. Immunoglobulin studies in children with inflammatory bowel disease. Ann Allergy. 1994 Jun; 72(6):525-7.
  22. Irons M, Elias ER, Tint GS, Salen G, Frieden R, Buie TM, Ampola M. Abnormal cholesterol metabolism in the Smith-Lemli-Opitz syndrome: report of clinical and biochemical findings in four patients and treatment in one patient. Am J Med Genet. 1994 May 01; 50(4):347-52.
  23. Biller JA, Flores A, Buie T, Mazor S, Katz AJ. Tetracycline-induced esophagitis in adolescent patients. J Pediatr. 1992 Jan; 120(1):144-5.
To schedule an appointment: Call 617-355-6058

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