Sarah De Ferranti MD MPH

Sarah De Ferranti, MD, MPH

Director, Preventive Cardiology Program

Assistant Professor of Pediatrics, Harvard Medical School

Medical Services

Specialties

  • Cardiology
  • Preventive Cardiology

Departments

  • Cardiology
  • Cardiovascular Program

Programs

  • Cardiology Outpatient Services
  • Preventive Cardiology Clinic
To schedule an appointment: Call 617-355-0955 or Request an Appointment

Experience and Education

Education

Undergraduate School

University of Michigan, 1991

Ann Arbor, MI

Graduate School, MPH

Tufts University, 1995

Boston, MA

Medical School

Tufts University School of Medicine, 1995

Boston, MA

Residency

Boston Children's Hospital, 1996-1999

Boston, MA

Fellowship

Boston Children's Hospital , 1999-2003

Boston, Ma

Certifications

  • Pediatrics, Pediatric Cardiology

Publications

Publications powered by Harvard Catalyst Profiles
  1. Urbina EM, de Ferranti SD. Lipid Screening in Children and Adolescents. JAMA. 2016 Aug 9; 316(6):589-91.
  2. Saunders T, Mackie TI, Shah S, Gooding H, de Ferranti SD, Leslie LK. Young adult and parent stakeholder perspectives on participation in patient-centered comparative effectiveness research. J Comp Eff Res. 2016 Aug; 5(5):487-97.
  3. Martinez EE, Forbes PW, O'Brien SE, de Ferranti SD. Census tract based income level and lipid levels in urban pediatric primary care: a retrospective study. BMC Pediatr. 2016; 16:86.
  4. Haas ME, Levenson AE, Sun X, Liao WH, Rutkowski JM, de Ferranti SD, Schumacher VA, Scherer PE, Salant DJ, Biddinger SB. The Role of Proprotein Convertase Subtilisin/Kexin Type 9 in Nephrotic Syndrome-Associated Hypercholesterolemia. Circulation. 2016 Jul 5; 134(1):61-72.
  5. Perak AM, Ning H, de Ferranti SD, Gooding HC, Wilkins JT, Lloyd-Jones DM. Long-Term Risk of Atherosclerotic Cardiovascular Disease in US Adults With the Familial Hypercholesterolemia Phenotype. Circulation. 2016 Jul 5; 134(1):9-19.
  6. Gooding HC, Sheldrick RC, Leslie LK, Shah S, de Ferranti SD, Mackie TI. Adolescent Perceptions of Cholesterol Screening Results: "Young Invincibles" or Developing Adults? J Adolesc Health. 2016 Aug; 59(2):162-70.
  7. de Ferranti SD, Rodday AM, Mendelson MM, Wong JB, Leslie LK, Sheldrick RC. Prevalence of Familial Hypercholesterolemia in the 1999 to 2012 United States National Health and Nutrition Examination Surveys (NHANES). Circulation. 2016 Mar 15; 133(11):1067-72.
  8. Levenson AE, Haas ME, Miao J, Brown RJ, de Ferranti SD, Muniyappa R, Biddinger SB. Effect of Leptin Replacement on PCSK9 in ob/ob Mice and Female Lipodystrophic Patients. Endocrinology. 2016 Apr; 157(4):1421-9.
  9. Mozaffarian D, Benjamin EJ, Go AS, Arnett DK, Blaha MJ, Cushman M, Das SR, de Ferranti S, Després JP, Fullerton HJ, Howard VJ, Huffman MD, Isasi CR, Jiménez MC, Judd SE, Kissela BM, Lichtman JH, Lisabeth LD, Liu S, Mackey RH, Magid DJ, McGuire DK, Mohler ER, Moy CS, Muntner P, Mussolino ME, Nasir K, Neumar RW, Nichol G, Palaniappan L, Pandey DK, Reeves MJ, Rodriguez CJ, Rosamond W, Sorlie PD, Stein J, Towfighi A, Turan TN, Virani SS, Woo D, Yeh RW, Turner MB. Executive Summary: Heart Disease and Stroke Statistics--2016 Update: A Report From the American Heart Association. Circulation. 2016 Jan 26; 133(4):447-54.
  10. Bohr AH, Fuhlbrigge RC, Pedersen FK, de Ferranti SD, Müller K. Premature subclinical atherosclerosis in children and young adults with juvenile idiopathic arthritis. A review considering preventive measures. Pediatr Rheumatol Online J. 2016; 14(1):3.
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  12. Mozaffarian D, Benjamin EJ, Go AS, Arnett DK, Blaha MJ, Cushman M, Das SR, de Ferranti S, Després JP, Fullerton HJ, Howard VJ, Huffman MD, Isasi CR, Jiménez MC, Judd SE, Kissela BM, Lichtman JH, Lisabeth LD, Liu S, Mackey RH, Magid DJ, McGuire DK, Mohler ER, Moy CS, Muntner P, Mussolino ME, Nasir K, Neumar RW, Nichol G, Palaniappan L, Pandey DK, Reeves MJ, Rodriguez CJ, Rosamond W, Sorlie PD, Stein J, Towfighi A, Turan TN, Virani SS, Woo D, Yeh RW, Turner MB. Heart Disease and Stroke Statistics-2016 Update: A Report From the American Heart Association. Circulation. 2016 Jan 26; 133(4):e38-360.
  13. Bottino CJ, de Ferranti SD, Meyers AF, Rhodes ET. Massachusetts Pediatricians' Views Toward Body Mass Index Screening in Schools: Continued Controversy. Clin Pediatr (Phila). 2016 Aug; 55(9):844-50.
  14. Crouter SE, de Ferranti SD, Whiteley J, Steltz SK, Osganian SK, Feldman HA, Hayman LL. Effect on Physical Activity of a Randomized Afterschool Intervention for Inner City Children in 3rd to 5th Grade. PLoS One. 2015; 10(10):e0141584.
  15. Gidding SS, Champagne MA, de Ferranti SD, Defesche J, Ito MK, Knowles JW, McCrindle B, Raal F, Rader D, Santos RD, Lopes-Virella M, Watts GF, Wierzbicki AS. The Agenda for Familial Hypercholesterolemia: A Scientific Statement From the American Heart Association. Circulation. 2015 Dec 1; 132(22):2167-92.
  16. Denhoff ER, Milliren CE, de Ferranti SD, Steltz SK, Osganian SK. Factors Associated with Clinical Research Recruitment in a Pediatric Academic Medical Center--A Web-Based Survey. PLoS One. 2015; 10(10):e0140768.
  17. Ronai C, Hamaoka-Okamoto A, Baker AL, de Ferranti SD, Colan SD, Newburger JW, Friedman KG. Coronary Artery Aneurysm Measurement and Z Score Variability in Kawasaki Disease. J Am Soc Echocardiogr. 2016 Feb; 29(2):150-7.
  18. de Ferranti SD, Milliren CE, Denhoff ER, Quinn N, Osganian SK, Feldman HA, Ebbeling CB, Ludwig DS. Providing food to treat adolescents at risk for cardiovascular disease. Obesity (Silver Spring). 2015 Oct; 23(10):2109-17.
  19. Gooding HC, Rodday AM, Wong JB, Gillman MW, Lloyd-Jones DM, Leslie LK, de Ferranti SD. Application of Pediatric and Adult Guidelines for Treatment of Lipid Levels Among US Adolescents Transitioning to Young Adulthood. JAMA Pediatr. 2015 Jun; 169(6):569-74.
  20. Mackie TI, Tse LL, de Ferranti SD, Ryan HR, Leslie LK. Treatment decision making for adolescents with familial hypercholesterolemia: Role of family history and past experiences. J Clin Lipidol. 2015 Jul-Aug; 9(4):583-93.e1-3.
  21. de Ferranti SD. Familial hypercholesterolemia in children and adolescents: A clinical perspective. J Clin Lipidol. 2015 Sep-Oct; 9(5 Suppl):S11-9.
  22. Mendelson MM, de Ferranti SD. Childhood environmental tobacco smoke exposure: a smoking gun for atherosclerosis in adulthood. Circulation. 2015 Apr 7; 131(14):1231-3.
  23. de Koning L, Denhoff E, Kellogg MD, de Ferranti SD. Associations of total and abdominal adiposity with risk marker patterns in children at high-risk for cardiovascular disease. BMC Obes. 2015; 2:15.
  24. Mozaffarian D, Benjamin EJ, Go AS, Arnett DK, Blaha MJ, Cushman M, de Ferranti S, Després JP, Fullerton HJ, Howard VJ, Huffman MD, Judd SE, Kissela BM, Lackland DT, Lichtman JH, Lisabeth LD, Liu S, Mackey RH, Matchar DB, McGuire DK, Mohler ER, Moy CS, Muntner P, Mussolino ME, Nasir K, Neumar RW, Nichol G, Palaniappan L, Pandey DK, Reeves MJ, Rodriguez CJ, Sorlie PD, Stein J, Towfighi A, Turan TN, Virani SS, Willey JZ, Woo D, Yeh RW, Turner MB. Heart disease and stroke statistics--2015 update: a report from the American Heart Association. Circulation. 2015 Jan 27; 131(4):e29-322.
  25. de Ferranti SD, Vinci SR, Gillman MW. Rates of cholesterol screening of youth--reply. JAMA. 2014 Oct 1; 312(13):1354.
  26. Maahs DM, Daniels SR, de Ferranti SD, Dichek HL, Flynn J, Goldstein BI, Kelly AS, Nadeau KJ, Martyn-Nemeth P, Osganian SK, Quinn L, Shah AS, Urbina E. Cardiovascular disease risk factors in youth with diabetes mellitus: a scientific statement from the American Heart Association. Circulation. 2014 Oct 21; 130(17):1532-58.
  27. de Ferranti SD, de Boer IH, Fonseca V, Fox CS, Golden SH, Lavie CJ, Magge SN, Marx N, McGuire DK, Orchard TJ, Zinman B, Eckel RH. Type 1 diabetes mellitus and cardiovascular disease: a scientific statement from the American Heart Association and American Diabetes Association. Circulation. 2014 Sep 23; 130(13):1110-30.
  28. de Ferranti SD, de Boer IH, Fonseca V, Fox CS, Golden SH, Lavie CJ, Magge SN, Marx N, McGuire DK, Orchard TJ, Zinman B, Eckel RH. Type 1 diabetes mellitus and cardiovascular disease: a scientific statement from the American Heart Association and American Diabetes Association. Diabetes Care. 2014 Oct; 37(10):2843-63.
  29. Zachariah JP, Graham DA, de Ferranti SD, Vasan RS, Newburger JW, Mitchell GF. Temporal trends in pulse pressure and mean arterial pressure during the rise of pediatric obesity in US children. J Am Heart Assoc. 2014 Jun; 3(3):e000725.
  30. Vinci SR, Rifas-Shiman SL, Cheng JK, Mannix RC, Gillman MW, de Ferranti SD. Cholesterol testing among children and adolescents during health visits. JAMA. 2014 May 7; 311(17):1804-7.
  31. de Ferranti SD, Milliren CE, Denhoff ER, Steltz SK, Selamet Tierney ES, Feldman HA, Osganian SK. Using high-dose omega-3 fatty acid supplements to lower triglyceride levels in 10- to 19-year-olds. Clin Pediatr (Phila). 2014 May; 53(5):428-38.
  32. Joshi M, Eagan J, Desai NK, Newton SA, Towne MC, Marinakis NS, Esteves KM, De Ferranti S, Bennett MJ, McIntyre A, Beggs AH, Berry GT, Agrawal PB. A compound heterozygous mutation in GPD1 causes hepatomegaly, steatohepatitis, and hypertriglyceridemia. Eur J Hum Genet. 2014 Oct; 22(10):1229-32.
  33. Urbina EM, de Ferranti S, Steinberger J. Observational studies may be more important than randomized clinical trials: weaknesses in US Preventive Services Task Force recommendation on blood pressure screening in youth. Hypertension. 2014 Apr; 63(4):638-40.
  34. Mendelson MM, Zachariah JP, de Ferranti SD, Bickel JP. Leveraging electronic health records to notify pediatric patients of a drug recall. JAMA Pediatr. 2013 Dec; 167(12):1170-1.
  35. Kelishadi R, de Ferranti SD, Majdzadeh R, O'Dea JA, Gupta AK, Adeli K. Childhood obesity: today and tomorrow's health challenge. J Obes. 2013; 2013:208392.
  36. Shah RV, Abbasi SA, Neilan TG, Hulten E, Coelho-Filho O, Hoppin A, Levitsky L, de Ferranti S, Rhodes ET, Traum A, Goodman E, Feng H, Heydari B, Harris WS, Hoefner DM, McConnell JP, Seethamraju R, Rickers C, Kwong RY, Jerosch-Herold M. Myocardial tissue remodeling in adolescent obesity. J Am Heart Assoc. 2013 Aug; 2(4):e000279.
  37. Selamet Tierney ES, Gal D, Gauvreau K, Baker AL, Trevey S, O'Neill SR, Jaff MR, de Ferranti S, Fulton DR, Colan SD, Newburger JW. Vascular health in Kawasaki disease. J Am Coll Cardiol. 2013 Sep 17; 62(12):1114-21.
  38. Longmuir PE, Brothers JA, de Ferranti SD, Hayman LL, Van Hare GF, Matherne GP, Davis CK, Joy EA, McCrindle BW. Promotion of physical activity for children and adults with congenital heart disease: a scientific statement from the American Heart Association. Circulation. 2013 May 28; 127(21):2147-59.
  39. Zachariah JP, de Ferranti SD. NHLBI integrated pediatric guidelines: battle for a future free of cardiovascular disease. Future Cardiol. 2013 Jan; 9(1):13-22.
  40. Kelishadi R, Poursafa P, de Ferranti SD, Schwandt P, Adeli K, Onat A, Gidding SS. Pediatric metabolic syndrome: from prevention to treatment. Cholesterol. 2012; 2012:374168.
  41. de Ferranti SD, Gillman MW. Hypertension in children and adolescents: more questions than answers. Arch Pediatr Adolesc Med. 2012 Sep; 166(9):872-4.
  42. de Ferranti SD. Declining cholesterol levels in US youths: a reason for optimism. JAMA. 2012 Aug 8; 308(6):621-2.
  43. de Ferranti SD, Daniels SR, Gillman M, Vernacchio L, Plutzky J, Baker AL. NHLBI Integrated Guidelines on Cardiovascular Disease Risk Reduction: can we clarify the controversy about cholesterol screening and treatment in childhood? Clin Chem. 2012 Dec; 58(12):1626-30.
  44. Farias M, Friedman KG, Powell AJ, de Ferranti SD, Marshall AC, Brown DW, Kulik TJ. Dynamic evolution of practice guidelines: analysis of deviations from assessment and management plans. Pediatrics. 2012 Jul; 130(1):93-8.
  45. de Ferranti SD. Childhood cholesterol disorders: the iceberg base or nondisease? Med Clin North Am. 2012 Jan; 96(1):141-54.
  46. Balagopal PB, de Ferranti SD, Cook S, Daniels SR, Gidding SS, Hayman LL, McCrindle BW, Mietus-Snyder ML, Steinberger J. Nontraditional risk factors and biomarkers for cardiovascular disease: mechanistic, research, and clinical considerations for youth: a scientific statement from the American Heart Association. Circulation. 2011 Jun 14; 123(23):2749-69.
  47. Goldberg AC, Hopkins PN, Toth PP, Ballantyne CM, Rader DJ, Robinson JG, Daniels SR, Gidding SS, de Ferranti SD, Ito MK, McGowan MP, Moriarty PM, Cromwell WC, Ross JL, Ziajka PE. Familial hypercholesterolemia: screening, diagnosis and management of pediatric and adult patients: clinical guidance from the National Lipid Association Expert Panel on Familial Hypercholesterolemia. J Clin Lipidol. 2011 Jun; 5(3 Suppl):S1-8.
  48. Daniels SR, Gidding SS, de Ferranti SD. Pediatric aspects of familial hypercholesterolemias: recommendations from the National Lipid Association Expert Panel on Familial Hypercholesterolemia. J Clin Lipidol. 2011 Jun; 5(3 Suppl):S30-7.
  49. Goldberg AC, Hopkins PN, Toth PP, Ballantyne CM, Rader DJ, Robinson JG, Daniels SR, Gidding SS, de Ferranti SD, Ito MK, McGowan MP, Moriarty PM, Cromwell WC, Ross JL, Ziajka PE. Familial hypercholesterolemia: screening, diagnosis and management of pediatric and adult patients: clinical guidance from the National Lipid Association Expert Panel on Familial Hypercholesterolemia. J Clin Lipidol. 2011 May-Jun; 5(3):133-40.
  50. de Ferranti SD, Crean S, Cotter J, Boyd D, Osganian SK. Hypertriglyceridemia in a pediatric referral practice: experience with 300 patients. Clin Pediatr (Phila). 2011 Apr; 50(4):297-307.
  51. Gooding HC, de Ferranti SD. Cardiovascular risk assessment and cholesterol management in adolescents: getting to the heart of the matter. Curr Opin Pediatr. 2010 Aug; 22(4):398-404.
  52. de Ferranti SD. Recovery from metabolic syndrome is both possible and beneficial. Clin Chem. 2010 Jul; 56(7):1053-5.
  53. Selamet Tierney ES, Newburger JW, Gauvreau K, Geva J, Coogan E, Colan SD, de Ferranti SD. Endothelial pulse amplitude testing: feasibility and reproducibility in adolescents. J Pediatr. 2009 Jun; 154(6):901-5.
  54. de Ferranti S, Ludwig DS. Storm over statins--the controversy surrounding pharmacologic treatment of children. N Engl J Med. 2008 Sep 25; 359(13):1309-12.
  55. de Ferranti S, Mozaffarian D. The perfect storm: obesity, adipocyte dysfunction, and metabolic consequences. Clin Chem. 2008 Jun; 54(6):945-55.
  56. De Ferranti SD, Osganian SK. Epidemiology of paediatric metabolic syndrome and type 2 diabetes mellitus. Diab Vasc Dis Res. 2007 Dec; 4(4):285-96.
  57. Pinto NM, Marino BS, Wernovsky G, de Ferranti SD, Walsh AZ, Laronde M, Hyland K, Dunn SO, Cohen MS. Obesity is a common comorbidity in children with congenital and acquired heart disease. Pediatrics. 2007 Nov; 120(5):e1157-64.
  58. de Ferranti S, Shapiro D, Markowitz R, Neufeld E, Rifai N, Bernstein H. Nonfasting low-density lipoprotein testing: utility for cholesterol screening in pediatric primary care. Clin Pediatr (Phila). 2007 Jun; 46(5):441-5.
  59. de Ferranti SD, Rifai N. C-reactive protein: a nontraditional serum marker of cardiovascular risk. Cardiovasc Pathol. 2007 Jan-Feb; 16(1):14-21.
  60. de Ferranti SD, Gauvreau K, Ludwig DS, Newburger JW, Rifai N. Inflammation and changes in metabolic syndrome abnormalities in US adolescents: findings from the 1988-1994 and 1999-2000 National Health and Nutrition Examination Surveys. Clin Chem. 2006 Jul; 52(7):1325-30.
  61. de Ferranti SD, Gauvreau K, Ludwig DS, Neufeld EJ, Newburger JW, Rifai N. Prevalence of the metabolic syndrome in American adolescents: findings from the Third National Health and Nutrition Examination Survey. Circulation. 2004 Oct 19; 110(16):2494-7.
  62. de Ferranti S, Gauvreau K, Hickey PR, Jonas RA, Wypij D, du Plessis A, Bellinger DC, Kuban K, Newburger JW, Laussen PC. Intraoperative hyperglycemia during infant cardiac surgery is not associated with adverse neurodevelopmental outcomes at 1, 4, and 8 years. Anesthesiology. 2004 Jun; 100(6):1345-52.
  63. de Ferranti S, Rifai N. C-reactive protein and cardiovascular disease: a review of risk prediction and interventions. Clin Chim Acta. 2002 Mar; 317(1-2):1-15.
  64. Yu HH, Markowitz R, De Ferranti SD, Neufeld EJ, Farrow G, Bernstein HH, Rifai N. Direct measurement of LDL-C in children: performance of two surfactant-based methods in a general pediatric population. Clin Biochem. 2000 Mar; 33(2):89-95.
  65. de Ferranti SD, Ioannidis JP, Lau J, Anninger WV, Barza M. Are amoxycillin and folate inhibitors as effective as other antibiotics for acute sinusitis? A meta-analysis. BMJ. 1998 Sep 5; 317(7159):632-7.
  66. Cappelleri JC, Ioannidis JP, Schmid CH, de Ferranti SD, Aubert M, Chalmers TC, Lau J. Large trials vs meta-analysis of smaller trials: how do their results compare? JAMA. 1996 Oct 23-30; 276(16):1332-8.
To schedule an appointment: Call 617-355-0955 or Request an Appointment

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