Ruth Ann Vleugels, MD

Attending Physician, Dermatology

Associate Professor of Dermatology, Harvard Medical School

    Contact: 617-355-6117
  • Fax: 617-730-0308

Medical Services


  • Medicine


  • Dermatology Program
To schedule an appointment: Call 617-355-6117 or Request an Appointment

Experience and Education


  • American Board of Dermatology


Publications powered by Harvard Catalyst Profiles
  1. Pinard J, Vleugels RA, Joyce C, Merola JF, Patel M. Hidradenitis suppurativa burden of disease tool: Pilot testing of a disease-specific quality of life questionnaire. J Am Acad Dermatol. 2018 Jan; 78(1):215-217.e2.
  2. Pinard J, Patel M, Granter SR, Vleugels RA, Merola JF. Subacute Cutaneous Lupus Erythematosus Induced by Palbociclib. J Cutan Med Surg. 2018 Jan 01; 1203475417752369.
  3. Kurtzman DJ, Vleugels RA. Anti-melanoma differentiation-associated gene 5 (MDA5) dermatomyositis: a concise review with an emphasis on distinctive clinical features. J Am Acad Dermatol. 2017 Dec 09.
  4. Mazori DR, Femia AN, Vleugels RA. Eosinophilic Fasciitis: an Updated Review on Diagnosis and Treatment. Curr Rheumatol Rep. 2017 Nov 04; 19(12):74.
  5. Bronckers IMGJ, Seyger MMB, West DP, Lara-Corrales I, Tollefson M, Tom WL, Hogeling M, Belazarian L, Zachariae C, Mahé E, Siegfried E, Philipp S, Szalai Z, Vleugels RA, Holland K, Murphy R, Baselga E, Cordoro K, Lambert J, Alexopoulos A, Mrowietz U, Kievit W, Paller AS. Safety of Systemic Agents for the Treatment of Pediatric Psoriasis. JAMA Dermatol. 2017 Nov 01; 153(11):1147-1157.
  6. Shi CR, Olbricht S, Vleugels RA, Nambudiri VE. Sex and leadership in academic dermatology: A nationwide survey. J Am Acad Dermatol. 2017 10; 77(4):782-784.
  7. Fruchter R, Kurtzman DJB, Patel M, Merola J, Franks AG, Vleugels RA, Femia AN. Characteristics and Alternative Treatment Outcomes of Antimalarial-Refractory Cutaneous Lupus Erythematosus. JAMA Dermatol. 2017 Sep 01; 153(9):937-939.
  8. Song P, Fett NM, Lin J, Merola JF, Costner M, Vleugels RA. Lack of Response to Intravenous Sodium Thiosulfate in Three Cases of Extensive Connective Tissue Disease-Associated Calcinosis Cutis. Br J Dermatol. 2017 Jul 01.
  9. Kurtzman DJB, Weinblatt M, Vleugels RA. Antimelanoma Differentiation-associated Gene 5 Dermatomyositis. J Rheumatol. 2017 Jun; 44(6):850-851.
  10. Bae GH, Kurtzman D, Granter SR, Vleugels RA, Nambudiri VE. Asymptomatic papules after breast cancer treatment. J Am Acad Dermatol. 2017 May; 76(5):e157-e158.
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  12. Bae GH, Kurtzman D, Granter SR, Vleugels RA, Nambudiri VE. Asymptomatic papules after breast cancer treatment. J Am Acad Dermatol. 2017 May; 76(5):e157-e158.
  13. Pinard J, Vleugels RA, Kurtzman DJ, Devlin PM, Patel M. Novel Application of High-Dose-Rate Brachytherapy for Severe, Recalcitrant Acrodermatitis Continua of Hallopeau. JAMA Dermatol. 2017 Apr 01; 153(4):331-332.
  14. Huard C, Gullà SV, Bennett DV, Coyle AJ, Vleugels RA, Greenberg SA. Correlation of cutaneous disease activity with type 1 interferon gene signature and interferon ß in dermatomyositis. Br J Dermatol. 2017 May; 176(5):1224-1230.
  15. Kurtzman DJ, Vleugels RA. Expanding the use of the Cutaneous Dermatomyositis Area and Severity Index (CDASI) to nondermatologists. Br J Dermatol. 2017 02; 176(2):296-297.
  16. Kurtzman DJ, Wright NA, Patel M, Vleugels RA. Segmental stiff skin syndrome (SSS): Two additional cases with a positive response to mycophenolate mofetil and physical therapy. J Am Acad Dermatol. 2016 Dec; 75(6):e237-e239.
  17. Fruchter R, Kurtzman DJB, Mazori DR, Wright NA, Patel M, Vleugels RA, Femia AN. Characteristics and treatment of postirradiation morphea: A retrospective multicenter analysis. J Am Acad Dermatol. 2017 Jan; 76(1):19-21.
  18. Kurtzman DJ, Ho A, Wright NA, Rubenstein MH, Vleugels RA. Unilateral Gottron Papules in a Patient Following a Stroke: Clinical Insights Into the Disease Mechanisms and Pathophysiology of Cutaneous Dermatomyositis. JAMA Dermatol. 2016 Sep 01; 152(9):1062-3.
  19. Kurtzman DJ, Wright NA, Lin J, Femia AN, Merola JF, Patel M, Vleugels RA. Tofacitinib Citrate for Refractory Cutaneous Dermatomyositis: An Alternative Treatment. JAMA Dermatol. 2016 Aug 01; 152(8):944-5.
  20. Nahmias Z, Nambudiri VE, Vleugels RA. Thalidomide and lenalidomide for the treatment of refractory dermatologic conditions. J Am Acad Dermatol. 2016 Jul; 75(1):210-2.
  21. Nambudiri VE, Qureshi AA, Vleugels RA. Sharps injuries among US dermatology trainees: A cross-sectional study. J Am Acad Dermatol. 2016 Apr; 74(4):756-8.
  22. Mazori DR, Wright NA, Patel M, Liu SW, Ramachandran SM, Franks AG, Vleugels RA, Femia AN. Characteristics and treatment of adult-onset linear morphea: A retrospective cohort study of 61 patients at 3 tertiary care centers. J Am Acad Dermatol. 2016 Mar; 74(3):577-9.
  23. Song JS, Halim K, Vleugels RA, Merola JF. Dapsone for treatment of erythema nodosum. Dermatol Online J. 2016 Feb 17; 22(2).
  24. Timerman D, Devlin PM, Nambudiri VE, Wright NA, Vleugels RA, Clark RA, Kupper TS, Merola JF, Patel M. Novel application of high-dose rate brachytherapy for severe, recalcitrant palmoplantar pustulosis. Clin Exp Dermatol. 2016 Jul; 41(5):498-501.
  25. Lam C, Liu SW, Townsend HB, Femia AN, Qureshi AA, Vleugels RA. Development and Pilot Testing of the Cutaneous Lupus Screening Tool. JAMA Dermatol. 2016 Jan; 152(1):60-6.
  26. Wright NA, Mazori DR, Patel M, Merola JF, Femia AN, Vleugels RA. Epidemiology and Treatment of Eosinophilic Fasciitis: An Analysis of 63 Patients From 3 Tertiary Care Centers. JAMA Dermatol. 2016 Jan; 152(1):97-9.
  27. Goddard AL, Vleugels RA, LeBoeuf NR, O'Farrell DA, Cormack RA, Hansen JL, Kupper TS, Devlin PM. Palliative Therapy for Recalcitrant Cutaneous T-Cell Lymphoma of the Hands and Feet With Low-Dose, High Dose-Rate Brachytherapy. JAMA Dermatol. 2015 Dec 01; 151(12):1354-1357.
  28. Wright NA, Vleugels RA, Callen JP. Cutaneous dermatomyositis in the era of biologicals. Semin Immunopathol. 2016 Jan; 38(1):113-21.
  29. Patel M, Cohen JM, Wright NA, Merola JF, Qureshi AA, Vleugels RA. Epidemiology of concomitant psoriasis and hidradenitis suppurativa (HS): experience of a tertiary medical center. J Am Acad Dermatol. 2015 Oct; 73(4):701-2.
  30. Winterfield L, Vleugels RA, Park KK. The Value of the Black Box Warning in Dermatology. J Drugs Dermatol. 2015 Jul; 14(7):660-6.
  31. Hu L, Alexander C, Velez NF, Yang C, Canales AL, Liu S, Vleugels RA. Severe Tacrolimus-Induced Granulomatous Rosacea Recalcitrant to Oral Tetracyclines. J Drugs Dermatol. 2015 Jun; 14(6):628-30.
  32. Ogbechie OA, Nambudiri VE, Vleugels RA. Teledermatology perception differences between urban primary care physicians and dermatologists. JAMA Dermatol. 2015 Mar; 151(3):339-40.
  33. Sheik Ali S, Goddard AL, Luke JJ, Donahue H, Todd DJ, Werchniak A, Vleugels RA. Drug-associated dermatomyositis following ipilimumab therapy: a novel immune-mediated adverse event associated with cytotoxic T-lymphocyte antigen 4 blockade. JAMA Dermatol. 2015 Feb; 151(2):195-9.
  34. Ogbechie OA, Eastham AB, Vleugels RA. Tense bullae on the palms and soles. JAMA Dermatol. 2015 Jan; 151(1):99-100.
  35. Patel M, Femia AN, Eastham AB, Lin J, Canales AL, Vleugels RA. Facial erythromelalgia: a rare entity to consider in the differential diagnosis of connective tissue diseases. J Am Acad Dermatol. 2014 Dec; 71(6):e250-1.
  36. Nambudiri VE, Vleugels RA, Laga AC, Goldberg LJ. Clinicopathologic lessons in distinguishing cicatricial alopecia: 7 cases of lichen planopilaris misdiagnosed as discoid lupus. J Am Acad Dermatol. 2014 Oct; 71(4):e135-8.
  37. Eastham AB, Femia AN, Velez NF, Smith HP, Vleugels RA. Paraproteinemia-associated scleredema treated successfully with intravenous immunoglobulin. JAMA Dermatol. 2014 Jul; 150(7):788-9.
  38. Eastham AB, Hornick J, Gaviola G, Vleugels RA. A 52-year-old woman with subcutaneous nodules and abdominal pain. Clin Exp Dermatol. 2014 Jun; 39(4):547-9.
  39. Wu S, Han J, Vleugels RA, Puett R, Laden F, Hunter DJ, Qureshi AA. Cumulative ultraviolet radiation flux in adulthood and risk of incident skin cancers in women. Br J Cancer. 2014 Apr 02; 110(7):1855-61.
  40. Nambudiri VE, Newman LR, Haynes HA, Schur P, Vleugels RA. Creation of a novel, interdisciplinary, multisite clerkship: "understanding lupus". Acad Med. 2014 Mar; 89(3):404-9.
  41. Eastham AB, Vleugels RA. Cutaneous lupus erythematosus. JAMA Dermatol. 2014 Mar; 150(3):344.
  42. Eastham AB, Femia AN, Qureshi A, Vleugels RA. Treatment options for pityriasis rubra pilaris including biologic agents: a retrospective analysis from an academic medical center. JAMA Dermatol. 2014 Jan; 150(1):92-4.
  43. Roh EK, Vleugels RA, Hoang MP. Case records of the Massachusetts General Hospital. Case 39-2013. A 57-year-old woman with painful bullous skin lesions. N Engl J Med. 2013 Dec 19; 369(25):2438-49.
  44. Zhou X, Velez NF, Farsani T, Tsiaras W, Laga AC, Werchniak AE, Vleugels RA. Multiple tense bullae localized to the right breast in a woman in her seventies. JAMA Dermatol. 2013 Dec; 149(12):1427-8.
  45. Eastham AB, Liang CA, Femia AN, Lee TC, Vleugels RA, Merola JF. Lupus erythematosus panniculitis-induced facial atrophy: effective treatment with poly-L-lactic acid and hyaluronic acid dermal fillers. J Am Acad Dermatol. 2013 Nov; 69(5):e260-2.
  46. Frankel HC, Sharon VR, Vleugels RA, Merola JF, Qureshi AA. Lower-dose thalidomide therapy effectively treats cutaneous lupus erythematosus but is limited by neuropathic toxicity. Int J Dermatol. 2013 Nov; 52(11):1407-9.
  47. Femia AN, Eastham AB, Lam C, Merola JF, Qureshi AA, Vleugels RA. Intravenous immunoglobulin for refractory cutaneous dermatomyositis: a retrospective analysis from an academic medical center. J Am Acad Dermatol. 2013 Oct; 69(4):654-7.
  48. Nguyen K, Vleugels RA, Velez NF, Merola JF, Qureshi AA. Psoriasiform reactions to anti-tumor necrosis factor a therapy. J Clin Rheumatol. 2013 Oct; 19(7):377-81.
  49. Liu SW, Velez NF, Lam C, Femia A, Granter SR, Townsend HB, Vleugels RA. Dermatomyositis induced by anti-tumor necrosis factor in a patient with juvenile idiopathic arthritis. JAMA Dermatol. 2013 Oct; 149(10):1204-8.
  50. Femia AN, Vleugels RA, Callen JP. Cutaneous dermatomyositis: an updated review of treatment options and internal associations. Am J Clin Dermatol. 2013 Aug; 14(4):291-313.
  51. Click JW, Qureshi AA, Vleugels RA. Methotrexate for the treatment of cutaneous dermatomyositis. J Am Acad Dermatol. 2013 Jun; 68(6):1043-5.
  52. Lam C, Vleugels RA. Images in clinical medicine. Epidermolysis bullosa acquisita. N Engl J Med. 2013 Mar 28; 368(13):e17.
  53. Eastham AB, Velez NF, Chesebro AL, Townsend HB, Vleugels RA. Diffuse dystrophic calcinosis cutis of the scalp in a patient with scalp discoid lupus erythematosus and systemic lupus erythematosus. JAMA Dermatol. 2013 Feb; 149(2):246-8.
  54. Velez NF, Ishizawar RC, Dellaripa PF, Saavedra AP, Laga AC, Murphy GF, Fisher DC, Kupper TS, Vleugels RA. Full facial edema: a novel presentation of subcutaneous panniculitis-like T-cell lymphoma. J Clin Oncol. 2012 Sep 01; 30(25):e233-6.
  55. Girouard SD, Velez NF, Penson RT, Massarotti EM, Vleugels RA. Panniculitis associated with dermatomyositis and recurrent ovarian cancer. Arch Dermatol. 2012 Jun; 148(6):740-4.
  56. Velez NF, Callen JP, Vleugels RA. Calcinosis cutis: an additional therapy to consider. J Am Acad Dermatol. 2012 Jun; 66(6):1004-5; author reply 1005.
  57. Gropper AB, Girouard SD, Hojman LP, Huang SJ, Qian X, Murphy GF, Vleugels RA. Metastatic basal cell carcinoma of the posterior neck: case report and review of the literature. J Cutan Pathol. 2012 May; 39(5):526-34.
  58. Lam C, Vleugels RA. Management of cutaneous dermatomyositis. Dermatol Ther. 2012 Mar-Apr; 25(2):112-34.
  59. Halvorsen JA, Vleugels RA, Bjertness E, Lien L. A population-based study of acne and body mass index in adolescents. Arch Dermatol. 2012 Jan; 148(1):131-2.
  60. Vedvyas C, Winterfield LS, Vleugels RA. Calciphylaxis: a systematic review of existing and emerging therapies. J Am Acad Dermatol. 2012 Dec; 67(6):e253-60.
  61. Vleugels RA. Identifying when therapy for one skin disease is likely to exacerbate another skin condition. Arch Dermatol. 2011 Jul; 147(7):836.
  62. Doyle LA, Sperling LC, Baksh S, Lackey J, Thomas B, Vleugels RA, Qureshi AA, Velazquez EF. Psoriatic alopecia/alopecia areata-like reactions secondary to anti-tumor necrosis factor-a therapy: a novel cause of noncicatricial alopecia. Am J Dermatopathol. 2011 Apr; 33(2):161-6.
  63. Badisco L, Marchal E, Van Wielendaele P, Verlinden H, Vleugels R, Vanden Broeck J. RNA interference of insulin-related peptide and neuroparsins affects vitellogenesis in the desert locust Schistocerca gregaria. Peptides. 2011 Mar; 32(3):573-80.
  64. Laga AC, Vleugels RA, Qureshi AA, Velazquez EF. Histopathologic spectrum of psoriasiform skin reactions associated with tumor necrosis factor-a inhibitor therapy. A study of 16 biopsies. Am J Dermatopathol. 2010 Aug; 32(6):568-73.
  65. Ross JJ, Saavedra A, Vleugels RA, Liu A, Castells MC. Interactive medical case. A rash hypothesis. N Engl J Med. 2010 Jun 17; 362(24):e69.
  66. Verlinden H, Vleugels R, Marchal E, Badisco L, Pflüger HJ, Blenau W, Broeck JV. The role of octopamine in locusts and other arthropods. J Insect Physiol. 2010 Aug; 56(8):854-67.
  67. Verlinden H, Vleugels R, Marchal E, Badisco L, Tobback J, Pflüger HJ, Blenau W, Vanden Broeck J. The cloning, phylogenetic relationship and distribution pattern of two new putative GPCR-type octopamine receptors in the desert locust (Schistocerca gregaria). J Insect Physiol. 2010 Aug; 56(8):868-75.
  68. Eshaghian A, Vleugels RA, Canter JA, McDonald MA, Stasko T, Sligh JE. Mitochondrial DNA deletions serve as biomarkers of aging in the skin, but are typically absent in nonmelanoma skin cancers. J Invest Dermatol. 2006 Feb; 126(2):336-44.
  69. Girald-Rosa W, Vleugels RA, Musiek AC, Sligh JE. High-throughput mitochondrial genome screening method for nonmelanoma skin cancer using multiplexed temperature gradient capillary electrophoresis. Clin Chem. 2005 Feb; 51(2):305-11.
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