Marvin Harper

Marvin Harper, MD

Senior Associate Physician in Medicine; Chief, Medical Information, Officer

Associate Professor of Pediatrics, Harvard Medical School

  • Contact: 617-355-6624

  • Fax: 617-730-0335

Medical Services


  • Infectious Disease
  • Emergency Medicine


  • Emergency Medicine
  • Infectious Diseases
  • Medicine


  • Division of Infectious Diseases
  • Emergency Medicine
To schedule an appointment: Call 617-355-6624

Experience and Education


Medical School

University of California, San Francisco, 1986

San Francisco, CA

Internship, Pediatrics

Boston Children's Hospital, 1986-1987

Boston, MA

Residency, Pediatrics

Boston Children's Hospital, 1987-1989

Boston, MA

Fellowship, Pediatric Infectious Diseases

Boston Children's Hospital, 1989-1992

Boston, MA

Fellowship, Pediatric Emergency Medicine

Boston Children's Hospital, 1990-1992

Boston, MA


  • Pediatrics

  • Pediatric Infectious Diseases

  • Pediatric Emergency Medicine


Infections in the Emergency Room


Publications powered by Harvard Catalyst Profiles
  1. Ganapathi L, Arnold A, Jones S, Patterson A, Graham D, Harper M, Levy O. Use of cidofovir in pediatric patients with adenovirus infection. F1000Res. 2016; 5:758.
  2. Cocoros NM, Kleinman K, Priebe GP, Gray JE, Logan LK, Larsen G, Sammons J, Toltzis P, Miroshnik I, Horan K, Burton M, Sims S, Harper M, Coffin S, Sandora TJ, Hocevar SN, Checchia PA, Klompas M, Lee GM. Ventilator-Associated Events in Neonates and Children--A New Paradigm. Crit Care Med. 2016 Jan; 44(1):14-22.
  3. Lebowitz MB, Olson KL, Burns M, Harper MB, Bourgeois F. Drug-Drug Interactions Among Hospitalized Children Receiving Chronic Antiepileptic Drug Therapy. Hosp Pediatr. 2016 May; 6(5):282-9.
  4. Kimia AA, Savova G, Landschaft A, Harper MB. An Introduction to Natural Language Processing: How You Can Get More From Those Electronic Notes You Are Generating. Pediatr Emerg Care. 2015 Jul; 31(7):536-41.
  5. Hron JD, Manzi S, Dionne R, Chiang VW, Brostoff M, Altavilla SA, Patterson AL, Harper MB. Electronic medication reconciliation and medication errors. Int J Qual Health Care. 2015 Aug; 27(4):314-9.
  6. Kimia AA, Bachur RG, Torres A, Harper MB. Febrile seizures: emergency medicine perspective. Curr Opin Pediatr. 2015 Jun; 27(3):292-7.
  7. Teufel RJ, Yu FB, Nakamura MM, Harper MB, Menachemi N. Factors associated with meaningful use incentives in children's hospitals. Pediatrics. 2015 Jun; 135(6):e1409-16.
  8. Bourgeois FC, Nigrin DJ, Harper MB. Preserving patient privacy and confidentiality in the era of personal health records. Pediatrics. 2015 May; 135(5):e1125-7.
  9. Gauguet S, Ahmed AA, Zhou J, Pfoh ER, Ahnger-Pier KK, Harper MB, Ozonoff A, Wessels MR, Lee GM. Group A streptococcal bacteremia without a source is associated with less severe disease in children. Pediatr Infect Dis J. 2015 Apr; 34(4):447-9.
  10. Nakamura MM, Harper MB, Castro AV, Yu FB, Jha AK. Impact of the meaningful use incentive program on electronic health record adoption by US children's hospitals. J Am Med Inform Assoc. 2015 Mar; 22(2):390-8.
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  12. Rudloe T, Prabhu SP, Gorman MP, Nigrovic LE, Harper MB, Landschaft A, Kimia AA. The Yield of Neuroimaging in Children Presenting to the Emergency Department With Acute Ataxia in the Post-Varicella Vaccine Era. J Child Neurol. 2015 Sep; 30(10):1333-9.
  13. Aprahamian N, Harper MB, Prabhu SP, Monuteaux MC, Sadiq Z, Torres A, Kimia AA. Pediatric first time non-febrile seizure with focal manifestations: is emergent imaging indicated? Seizure. 2014 Oct; 23(9):740-5.
  14. Harper MB, Longhurst CA, McGuire TL, Tarrago R, Desai BR, Patterson A. Core drug-drug interaction alerts for inclusion in pediatric electronic health records with computerized prescriber order entry. J Patient Saf. 2014 Mar; 10(1):59-63.
  15. Starmer AJ, Sectish TC, Simon DW, Keohane C, McSweeney ME, Chung EY, Yoon CS, Lipsitz SR, Wassner AJ, Harper MB, Landrigan CP. Rates of medical errors and preventable adverse events among hospitalized children following implementation of a resident handoff bundle. JAMA. 2013 Dec 4; 310(21):2262-70.
  16. Demirjian A, Finkelstein Y, Nava-Ocampo A, Arnold A, Jones S, Monuteaux M, Sandora TJ, Patterson A, Harper MB. A randomized controlled trial of a vancomycin loading dose in children. Pediatr Infect Dis J. 2013 Nov; 32(11):1217-23.
  17. Baskin MN, Goh XL, Heeney MM, Harper MB. Bacteremia risk and outpatient management of febrile patients with sickle cell disease. Pediatrics. 2013 Jun; 131(6):1035-41.
  18. Nakamura MM, Harper MB, Jha AK. Change in adoption of electronic health records by US children's hospitals. Pediatrics. 2013 May; 131(5):e1563-75.
  19. Hoffman JM, Zorc JJ, Harper MB. IT in the ED: past, present, and future. Pediatr Emerg Care. 2013 Mar; 29(3):402-5.
  20. Tibbles CD, Bouton M, Lucas JM, Harper M, Horwitz C, Fisher J. Emergency department management of pediatric patients with cyanotic heart disease and fever. J Emerg Med. 2013 Mar; 44(3):599-604.
  21. Zorc JJ, Hoffman JM, Harper MB. IT in the ED: a new section of Pediatric Emergency Care. Pediatr Emerg Care. 2012 Dec; 28(12):1399-401.
  22. Capraro A, Stack A, Harper MB, Kimia A. Detecting unapproved abbreviations in the electronic medical record. Jt Comm J Qual Patient Saf. 2012 Apr; 38(4):178-83.
  23. Kimia AA, Ben-Joseph E, Prabhu S, Rudloe T, Capraro A, Sarco D, Hummel D, Harper M. Yield of emergent neuroimaging among children presenting with a first complex febrile seizure. Pediatr Emerg Care. 2012 Apr; 28(4):316-21.
  24. Kimia AA, Johnston P, Capraro A, Harper MB. Occurrence of metabolic acidosis in pediatric emergency department patients as a data source for disease surveillance systems. Pediatr Emerg Care. 2010 Oct; 26(10):733-8.
  25. Kimia A, Ben-Joseph EP, Rudloe T, Capraro A, Sarco D, Hummel D, Johnston P, Harper MB. Yield of lumbar puncture among children who present with their first complex febrile seizure. Pediatrics. 2010 Jul; 126(1):62-9.
  26. Rudloe TF, Harper MB, Prabhu SP, Rahbar R, Vanderveen D, Kimia AA. Acute periorbital infections: who needs emergent imaging? Pediatrics. 2010 Apr; 125(4):e719-26.
  27. Melendez E, Harper MB. Risk of serious bacterial infection in isolated and unsuspected neutropenia. Acad Emerg Med. 2010 Feb; 17(2):163-7.
  28. Elliot Melendez, MD and Marvin B. Harper, MD. Risk of Serious Bacterial Infection in Isolated and Unsuspected Neutropenia. Acad Emerg Med 'In press'. 2010; 17:1-5.
  29. Rudloe TF, Harper MB, Prabhu SP, Rahbar R, VanderVeen D, Kimia AA. . Acute Periorbital Infections: Who Needs Emergent Imaging?. Pediatrics. Accepted for publication. 2010.
  30. James C, Harper M, Johnston P, Sanders B, Shannon M. Effect of trainees on length of stay in the pediatric emergency department. Acad Emerg Med. 2009 Sep; 16(9):859-65.
  31. Sandora TJ, Desai R, Miko BA, Harper MB. Assessing quality indicators for pediatric community-acquired pneumonia. Am J Med Qual. 2009 Sep-Oct; 24(5):419-27.
  32. Kimia AA, Capraro AJ, Hummel D, Johnston P, Harper MB. Utility of lumbar puncture for first simple febrile seizure among children 6 to 18 months of age. Pediatrics. 2009 Jan; 123(1):6-12.
  33. Rutman MS, Bachur R, Harper MB. Radiographic pneumonia in young, highly febrile children with leukocytosis before and after universal conjugate pneumococcal vaccination. Pediatr Emerg Care. 2009 Jan; 25(1):1-7.
  34. Bonsu BK, Ortega HW, Marcon MJ, Harper MB. A decision rule for predicting bacterial meningitis in children with cerebrospinal fluid pleocytosis when gram stain is negative or unavailable. Acad Emerg Med. 2008 May; 15(5):437-44.
  35. Neuman MI, Tolford S, Harper MB. Test characteristics and interpretation of cerebrospinal fluid gram stain in children. Pediatr Infect Dis J. 2008 Apr; 27(4):309-13.
  36. Harper MB, Mao C. Antimicrobials and Infectious Diseases. Manual of Pediatric Therapeutics. Editors Graef JW, Wolfsdorf JI, Greenes DS. 2008; 80-174.
  37. Harper MB . The toddler with fever. Pediatric Infectious Diseases. The Requisites in Pediatrics. Editors Bergelson JM, Shah SS, Zaoutis TE. 2008; 245-250.
  38. Harper MB. Pneumonia. Pediatric Infectious Diseases. The Requisites in Pediatrics. Editors Bergelson JM, Shah SS, Zaoutis TE. 2008; 117-124.
  39. McIntosh K, Harper M, Murray D. Pneumonia in the immunocompromised host. Principles and Practice of Pediatric Infectious Diseases. Editors Long SS, Pickering LK, Prober CG. 2008; 265-9.
  40. Harper M. Infection following bites. Principles and Practice of Pediatric Infectious Diseases. Editors Long SS, Pickering LK, Prober CG. 2008; 525-30.
  41. Bonsu BK, Harper MB. Leukocyte counts in urine reflect the risk of concomitant sepsis in bacteriuric infants: a retrospective cohort study. BMC Pediatr. 2007; 7:24.
  42. Neuman MI, Kelley M, Harper MB, File TM, Camargo CA. Factors associated with antimicrobial resistance and mortality in pneumococcal bacteremia. J Emerg Med. 2007 May; 32(4):349-57.
  43. Murphy CG, van de Pol AC, Harper MB, Bachur RG. Clinical predictors of occult pneumonia in the febrile child. Acad Emerg Med. 2007 Mar; 14(3):243-9.
  44. Olshen E, Hsu K, Woods ER, Harper M, Harnisch B, Samples CL. Use of human immunodeficiency virus postexposure prophylaxis in adolescent sexual assault victims. Arch Pediatr Adolesc Med. 2006 Jul; 160(7):674-80.
  45. Nigrovic LE, Nigrovic PA, Harper MB, Chiang VW. Extreme thrombocytosis predicts Kawasaki disease in infants. Clin Pediatr (Phila). 2006 Jun; 45(5):446-52.
  46. Nagler J, Harper MB, Bachur RG. An automated electronic case log: using electronic information systems to assess training in emergency medicine. Acad Emerg Med. 2006 Jul; 13(7):733-9.
  47. Willwerth BM, Harper MB, Greenes DS. Identifying hospitalized infants who have bronchiolitis and are at high risk for apnea. Ann Emerg Med. 2006 Oct; 48(4):441-7.
  48. Bonsu BK, Harper MB. Corrections for leukocytes and percent of neutrophils do not match observations in blood-contaminated cerebrospinal fluid and have no value over uncorrected cells for diagnosis. Pediatr Infect Dis J. 2006 Jan; 25(1):8-11.
  49. Harper, MB. Sexually Transmitted Diseases. Textbook of Pediatric Emergency Medicine. Editors: Fleisher and Ludwig. 2006; 853-871.
  50. Sandora TJ, Harper MB. Pneumonia in hospitalized children. Pediatr Clin North Am. 2005 Aug; 52(4):1059-81, viii.
  51. Bonsu BK, Harper MB. Accuracy and test characteristics of ancillary tests of cerebrospinal fluid for predicting acute bacterial meningitis in children with low white blood cell counts in cerebrospinal fluid. Acad Emerg Med. 2005 Apr; 12(4):303-9.
  52. Harper, M. Fever. Signs and Symptoms In Pediatrics. Edited by Davis MA, Gruskin KD, Chiang VW, Manzi S, Davis MA. 2005; 183-198.
  53. Bonsu BK, Harper MB. A low peripheral blood white blood cell count in infants younger than 90 days increases the odds of acute bacterial meningitis relative to bacteremia. Acad Emerg Med. 2004 Dec; 11(12):1297-301.
  54. Bonsu BK, Harper MB. Explanation of mathematical model. Pediatr Infect Dis J. 2004 Sep; 23(9):893.
  55. Saidinejad M, Burns MM, Harper MB. Disseminated histoplasmosis in a nonendemic area. Pediatr Infect Dis J. 2004 Aug; 23(8):781-2.
  56. Bonsu BK, Harper MB. Differentiating acute bacterial meningitis from acute viral meningitis among children with cerebrospinal fluid pleocytosis: a multivariable regression model. Pediatr Infect Dis J. 2004 Jun; 23(6):511-7.
  57. Goodkin HP, Harper MB, Pomeroy SL. Intracerebral abscess in children: historical trends at Children's Hospital Boston. Pediatrics. 2004 Jun; 113(6):1765-70.
  58. Harper, MB. Update on the Management of the Febrile Infant. Clinical Pediatric Emergency Medicine. 2004; 5(1):5-12.
  59. Melendez E, Harper MB. Utility of sepsis evaluation in infants 90 days of age or younger with fever and clinical bronchiolitis. Pediatr Infect Dis J. 2003 Dec; 22(12):1053-6.
  60. Neuman MI, Harper MB. Evaluation of a rapid urine antigen assay for the detection of invasive pneumococcal disease in children. Pediatrics. 2003 Dec; 112(6 Pt 1):1279-82.
  61. Bonsu BK, Chb M, Harper MB. Identifying febrile young infants with bacteremia: is the peripheral white blood cell count an accurate screen? Ann Emerg Med. 2003 Aug; 42(2):216-25.
  62. Willwerth BM, Harper MB, Mandl KD. Prolonged partial thromboplastin times in children with fever and petechiae without bacteremia or sepsis. Pediatr Emerg Care. 2003 Aug; 19(4):244-7.
  63. The ATOMIC Clinical Consensus Panel. Members: Christopher N, Conners GP, Gaspari R, Glauser J, Goepp J, Harper M, Hostetler MA, Lang DM, Manno M, Samadi R, Ernest S. Antibiotic Therapy for Otitis Media In Children (ATOMIC)—Patient Risk Stratification and Evidence-Based Selection of Antimicrobial Therapy. Emergency Medicine Consensus Reports. 2003; 1-18.
  64. Kocher MS, Mandiga R, Murphy JM, Goldmann D, Harper M, Sundel R, Ecklund K, Kasser JR. A clinical practice guideline for treatment of septic arthritis in children: efficacy in improving process of care and effect on outcome of septic arthritis of the hip. J Bone Joint Surg Am. 2003 Jun; 85-A(6):994-9.
  65. Bonsu BK, Harper MB. Utility of the peripheral blood white blood cell count for identifying sick young infants who need lumbar puncture. Ann Emerg Med. 2003 Feb; 41(2):206-14.
  66. Sharma S, Riviello JJ, Harper MB, Baskin MN. The role of emergent neuroimaging in children with new-onset afebrile seizures. Pediatrics. 2003 Jan; 111(1):1-5.
  67. McIntosh K, Harper M. Pneumonia in the immunocompromised host. Principles and Practice of Pediatric Infectious Diseases. Editors Long SS, Pickering LK, Prober CG. 2003; 237-241.
  68. McIntosh K, Harper M. Persistent and recurrent pneumonia. Principles and Practice of Pediatric Infectious Diseases. Editors Long SS, Pickering LK, Prober CG. 2003; 231-237.
  69. McIntosh K, Harper M. Complications of acute pneumonia. Principles and Practice of Pediatric Infectious Diseases. Editors Long SS, Pickering LK, Prober CG. 2003; 225-231.
  70. Neuman MI, Harper MB. Rapid antigen assay for the diagnosis of pneumococcal bacteremia in children: a preliminary study. Ann Emerg Med. 2002 Oct; 40(4):399-404.
  71. Isaacman DJ, Poirier MP, Harper M, Neuman M, Trainor J, Bell LM. Infectious diseases. Pediatr Emerg Care. 2002 Apr; 18(2):125-9.
  72. Harper MB. Human Immunodeficiency Virus Infection. In Synopsis of Pediatric Emergency Medicine; Editors: Fleisher and Ludwig. 2002; 326-331.
  73. Lee GM, Fleisher GR, Harper MB. Management of febrile children in the age of the conjugate pneumococcal vaccine: a cost-effectiveness analysis. Pediatrics. 2001 Oct; 108(4):835-44.
  74. Neuman MI, Harper MB. Time to positivity of blood cultures for children with Streptococcus pneumoniae bacteremia. Clin Infect Dis. 2001 Oct 15; 33(8):1324-8.
  75. Bachur RG, Harper MB. Predictive model for serious bacterial infections among infants younger than 3 months of age. Pediatrics. 2001 Aug; 108(2):311-6.
  76. Waltzman ML, Harper M. Financial and clinical impact of false-positive blood culture results. Clin Infect Dis. 2001 Aug 1; 33(3):296-9.
  77. Harper MB. Fever. Audio-Digest: Emergency Medicine. 2001; 18(9).
  78. Rhein L, Fleisher GR, Harper MB. Lack of reduction in hospitalizations and emergency department visits for varicella in the first 2 years post-vaccine licensure. Pediatr Emerg Care. 2001 Apr; 17(2):101-3.
  79. Bonsu BK, Harper MB. Fever interval before diagnosis, prior antibiotic treatment, and clinical outcome for young children with bacterial meningitis. Clin Infect Dis. 2001 Feb 15; 32(4):566-72.
  80. Bachur R, Harper MB. Reliability of the urinalysis for predicting urinary tract infections in young febrile children. Arch Pediatr Adolesc Med. 2001 Jan; 155(1):60-5.
  81. Bachur RB, Harper MB. Lyme disease. eMedicine. 2001.
  82. Bachur RB, Harper MB. Pneumococcal bacteremia. eMedicine. 2001.
  83. Harper MB. Information System applications in the Emergency Department. Clinical Pediatric Emergency Medicine. 2001.
  84. Kaplan RL, Harper MB, Baskin MN, Macone AB, Mandl KD. Time to detection of positive cultures in 28- to 90-day-old febrile infants. Pediatrics. 2000 Dec; 106(6):E74.
  85. Isaacman DJ, Shults J, Gross TK, Davis PH, Harper M. Predictors of bacteremia in febrile children 3 to 36 months of age. Pediatrics. 2000 Nov; 106(5):977-82.
  86. Harper MB, Lee GM. The pediatric forum: white blood cell count likelihood ratios for bacteremia in febrile young children Arch Pediatr Adolesc Med. 2000 Sep; 154(9):963-4.
  87. Bachur R, Harper MB. Reevaluation of outpatients with Streptococcus pneumoniae bacteremia. Pediatrics. 2000 Mar; 105(3 Pt 1):502-9.
  88. Harper MB. Human Immunodeficiency Virus Infection. Textbook of Pediatric Emergency Medicine; Editors: Fleisher and Ludwig. 2000; 795-809.
  89. Chumpa A, Bachur RG, Harper MB. Bacteremia-associated pneumococcal pneumonia and the benefit of initial parenteral antimicrobial therapy. Pediatr Infect Dis J. 1999 Dec; 18(12):1081-5.
  90. Zaidi E, Bachur R, Harper M. Non-typhi Salmonella bacteremia in children. Pediatr Infect Dis J. 1999 Dec; 18(12):1073-7.
  91. Harper MB. Nasopharyngeal colonization with pathogens causing otitis media: how does this information help us? Pediatr Infect Dis J. 1999 Dec; 18(12):1120-4.
  92. Harper MB. Bacteraemia in young children with high fever: still no easy answers. Med J Aust. 1999 May 17; 170(10):462-3.
  93. Greenes DS, Harper MB. Low risk of bacteremia in febrile children with recognizable viral syndromes. Pediatr Infect Dis J. 1999 Mar; 18(3):258-61.
  94. Bachur R, Perry H, Harper MB. Occult pneumonias: empiric chest radiographs in febrile children with leukocytosis. Ann Emerg Med. 1999 Feb; 33(2):166-73.
  95. Silverstein M, Bachur R, Harper MB. Clinical implications of penicillin and ceftriaxone resistance among children with pneumococcal bacteremia. Pediatr Infect Dis J. 1999 Jan; 18(1):35-41.
  96. Peña BM, Harper MB, Fleisher GR. Occult bacteremia with group B streptococci in an outpatient setting. Pediatrics. 1998 Jul; 102(1 Pt 1):67-72.
  97. Lee GM, Harper MB. Risk of bacteremia for febrile young children in the post-Haemophilus influenzae type b era. Arch Pediatr Adolesc Med. 1998 Jul; 152(7):624-8.
  98. Rothrock SG, Green SM, Harper MB, Clark MC, McIlmail DP, Bachur R. Parenteral vs oral antibiotics in the prevention of serious bacterial infections in children with Streptococcus pneumoniae occult bacteremia: a meta-analysis. Acad Emerg Med. 1998 Jun; 5(6):599-606.
  99. Rothrock SG, Harper MB, Green SM, Clark MC, Bachur R, McIlmail DP, Giordano PA, Falk JL. Do oral antibiotics prevent meningitis and serious bacterial infections in children with Streptococcus pneumoniae occult bacteremia? A meta-analysis. Pediatrics. 1997 Mar; 99(3):438-44.
  100. Huskins WC, Harper MB. . Antibiotics and Infectious Disorders. Manual of Pediatric Therapeutics. 1997; 76-164.
  101. Mao C, Harper M, McIntosh K, Reddington C, Cohen J, Bachur R, Caldwell B, Hsu HW. Invasive pneumococcal infections in human immunodeficiency virus-infected children. J Infect Dis. 1996 Apr; 173(4):870-6.
  102. Doctor A, Harper MB, Fleisher GR. Group A beta-hemolytic streptococcal bacteremia: historical overview, changing incidence, and recent association with varicella. Pediatrics. 1995 Sep; 96(3 Pt 1):428-33.
  103. Harper MB, Bachur R, Fleisher GR. Effect of antibiotic therapy on the outcome of outpatients with unsuspected bacteremia. Pediatr Infect Dis J. 1995 Sep; 14(9):760-7.
  104. Jaramillo D, Treves ST, Kasser JR, Harper M, Sundel R, Laor T. Osteomyelitis and septic arthritis in children: appropriate use of imaging to guide treatment. AJR Am J Roentgenol. 1995 Aug; 165(2):399-403.
  105. Harper MB. Pediatric infectious disease emergencies. Curr Opin Pediatr. 1995 Jun; 7(3):302-8.
  106. Harper MB, Wisian NB. Care of bereaved parents. A study of patient satisfaction. J Reprod Med. 1994 Feb; 39(2):80-6.
  107. Cohen-Abbo A, Harper MB. Case report: streptococcal toxic shock syndrome presenting as septic thrombophlebitis in a child with varicella. Pediatr Infect Dis J. 1993 Dec; 12(12):1033-4.
  108. Pinkert H, Harper MB, Cooper T, Fleisher GR. HIV-infected children in the pediatric emergency department. Pediatr Emerg Care. 1993 Oct; 9(5):265-9.
  109. Harper MB, Fleisher GR. Occult bacteremia in the 3-month-old to 3-year-old age group. Pediatr Ann. 1993 Aug; 22(8):484, 487-93.
To schedule an appointment: Call 617-355-6624


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