Jurriaan Peters MD

Jurriaan Peters, MD

Assistant in Neurology

Assistant Professor of Neurology, Harvard Medical School

  • Contact: 617-355-5606

  • Fax: 617-730-0463

"I find that forming a diagnostic and therapeutic alliance with parents can really positively impact the lives of patients and their families."

Medical Services

Specialties

  • Echocardiography
  • Epilepsy
  • Epilepsy Seizures
  • Epilepsy Surgery
  • Tuberous Sclerosis

Departments

  • Neurology

Languages

  • English
  • Dutch

Programs

  • Epilepsy Center
  • Tuberous Sclerosis Program
To schedule an appointment: Call 617-355-5606 or Request an Appointment
Jurriaan Peters MD

I was fascinated by science and discovery from a young age on, and by the brain in particular. 

It is amazing that science can be applied to humans, so it is less abstract than mathematics or physics. But it is exactly the clinical application of novel technologies and innovations that can drive patient care forward and change the field.

Clinically, I am amazed by how hard work and a sustained effort in care can make a difference, not on a group level, but for individual patients. I believe strongly in “putting up a good fight”, as it often pays off. In that, I find that forming a diagnostic and therapeutic alliance with parents, and if needed with colleagues, can really positively impact the lives of patients and their families. 

Experience and Education

Education

Medical School

Faculty of Medicine, Catholic University of Leuven , 1994 - 2002

Leuven, Belgium

Residency

Adult Neurology, VU University Medical Center Amsterdam, 2002-2003

Amsterdam, Netherlands

Residency

Adult Neurology, Haga Teaching Hospital, 2003-2006

Fellowship

Epilepsy & Clinical Neurophysiology, Boston Children’s Hospital, Harvard Medical School, 2006-2007

Boston, Massachusetts

Residency

Child Neurology, Boston Children’s Hospital, 2007 - 2010

Boston, Massachusetts

Internship

Pediatrics, Boston Combined Residency in Pediatrics program, Harvard Medical School/Boston University, 2010-2011

Boston, Massachusetts

Fellowship

Neuroimaging at Neurology (ABPN Neuroscience Track), Boston Children’s Hospital, Harvard Medical School, 2011-2012

Boston, Massachusetts

Certifications

  • American Board of Clinical Neurophysiology (ABCN)

  • Neurology with Special Qualification in Child Neurology

Professional History

I was trained as an adult neurologist, a child neurologist and clinical neurophysiologist, and have expertise in EEG signal processing, advanced neuroimaging and their clinical application to patients.

Throughout my career I have operated on the boundary between clinical care and cutting edge novel technologies. For children undergoing epilepsy surgery, we provide tailored imaging and EEG solutions for specific clinical problems, to optimize the chances of successful surgery and minimize surgical injury to functional areas. These innovations include the clinical application of patient-specific DTI tractography, 3D-renderings of the subdural electrode grids on the MRI brain surface, quantitative validation of the use of EEG during the Wada test, novel approaches to electrical source analysis.

I am the dedicated epileptologist in the multidisciplinary TSC program at Boston Children's Hospital, and TSC forms a major research focus. We have described an altered microstructural integrity in autism, suggesting the use of DTI as a biomarker for neurological outcome in TSC. Next, using EEG functional connectivity measures, we found alterations of brain network properties common to both idiopathic and TSC-related autism. More recently, we have described that tubers are neither static nor discrete over time.

Publications

Publications powered by Harvard Catalyst Profiles
  1. Erem B, Martinez Orellana R, Hyde DE, Peters JM, Duffy FH, Stovicek P, Warfield SK, MacLeod RS, Tadmor G, Brooks DH. Extensions to a manifold learning framework for time-series analysis on dynamic manifolds in bioelectric signals. Phys Rev E. 2016 Apr; 93(4):042218.
  2. Patel AA, Ciccone O, Njau A, Shanungu S, Grollnek AK, Fredrick F, Hodgeman R, Sideridis GD, Kapur K, Harini C, Kija E, Peters JM. A pediatric epilepsy diagnostic tool for use in resource-limited settings: A pilot study. Epilepsy Behav. 2016 Jun; 59:57-61.
  3. Taquet M, Scherrer B, Boumal N, Peters JM, Macq B, Warfield SK. Improved fidelity of brain microstructure mapping from single-shell diffusion MRI. Med Image Anal. 2015 Dec; 26(1):268-86.
  4. Peters JM, Prohl AK, Tomas-Fernandez XK, Taquet M, Scherrer B, Prabhu SP, Lidov HG, Singh JM, Jansen FE, Braun KP, Sahin M, Warfield SK, Stamm A. Tubers are neither static nor discrete: Evidence from serial diffusion tensor imaging. Neurology. 2015 Nov 3; 85(18):1536-45.
  5. Wu JY, Peters JM, Goyal M, Krueger D, Sahin M, Northrup H, Au KS, Cutter G, Bebin EM. Clinical Electroencephalographic Biomarker for Impending Epilepsy in Asymptomatic Tuberous Sclerosis Complex Infants. Pediatr Neurol. 2016 Jan; 54:29-34.
  6. Davis PE, Peters JM, Krueger DA, Sahin M. Tuberous Sclerosis: A New Frontier in Targeted Treatment of Autism. Neurotherapeutics. 2015 Jul; 12(3):572-83.
  7. Walsh BH, Baumer FM, Bernson-Leung ME, Lerou P, Peters JM. Teaching video neuroimages: nonepileptic myoclonus in a neonate following severe hypoxic-ischemic injury. Neurology. 2015 Mar 24; 84(12):e90.
  8. Im K, Ahtam B, Haehn D, Peters JM, Warfield SK, Sahin M, Ellen Grant P. Altered Structural Brain Networks in Tuberous Sclerosis Complex. Cereb Cortex. 2016 May; 26(5):2046-58.
  9. Pinto AL, Fernández IS, Peters JM, Manganaro S, Singer JM, Vendrame M, Prabhu SP, Loddenkemper T, Kothare SV. Localization of sleep spindles, k-complexes, and vertex waves with subdural electrodes in children. J Clin Neurophysiol. 2014 Aug; 31(4):367-74.
  10. Thome-Souza S, Kadish NE, Ramgopal S, Sánchez Fernández I, Bergin AM, Bolton J, Harini C, Libenson M, Olson H, Peters J, Poduri A, Rotenberg A, Takeoka M, Kothare SV, Kapur K, Bourgeois BF, Loddenkemper T. Safety and retention rate of rufinamide in 300 patients: a single pediatric epilepsy center experience. Epilepsia. 2014 Aug; 55(8):1235-44.
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  12. Sánchez Fernández I, Chapman K, Peters JM, Klehm J, Jackson MC, Berg AT, Loddenkemper T. Treatment for continuous spikes and waves during sleep (CSWS): survey on treatment choices in North America. Epilepsia. 2014 Jul; 55(7):1099-108.
  13. Klehm J, Thome-Souza S, Sánchez Fernández I, Bergin AM, Bolton J, Harini C, Kadish NE, Libenson M, Peters J, Poduri A, Rotenberg A, Takeoka M, Bourgeois B, Loddenkemper T. Clobazam: effect on frequency of seizures and safety profile in different subgroups of children with epilepsy. Pediatr Neurol. 2014 Jul; 51(1):60-6.
  14. Taquet M, Scherrer B, Peters JM, Prabhu SP, Warfield SK. A fully Bayesian inference framework for population studies of the brain microstructure. Med Image Comput Comput Assist Interv. 2014; 17(Pt 1):25-32.
  15. Peters JM, Fernández IS. Insult to injury: transient encephalopathy in a brain-injured adolescent. J Paediatr Child Health. 2014 May; 50(5):411-4.
  16. Tanaka N, Peters JM, Prohl AK, Takaya S, Madsen JR, Bourgeois BF, Dworetzky BA, Hämäläinen MS, Stufflebeam SM. Clinical value of magnetoencephalographic spike propagation represented by spatiotemporal source analysis: correlation with surgical outcome. Epilepsy Res. 2014 Feb; 108(2):280-8.
  17. Taquet M, Scherrer B, Commowick O, Peters JM, Sahin M, Macq B, Warfield SK. A mathematical framework for the registration and analysis of multi-fascicle models for population studies of the brain microstructure. IEEE Trans Med Imaging. 2014 Feb; 33(2):504-17.
  18. Sánchez Fernández I, Peters JM, An S, Bergin AM, Takeoka M, Rotenberg A, Kothare SV, Riviello JJ, Loddenkemper T. Long-term response to high-dose diazepam treatment in continuous spikes and waves during sleep. Pediatr Neurol. 2013 Sep; 49(3):163-170.e4.
  19. Sánchez Fernández I, Chapman KE, Peters JM, Harini C, Rotenberg A, Loddenkemper T. Continuous Spikes and Waves during Sleep: Electroclinical Presentation and Suggestions for Management. Epilepsy Res Treat. 2013; 2013:583531.
  20. Taquet M, Peters JM. [The brain functional network of children with autism: redundancy and disconnection]. Med Sci (Paris). 2013 Jun-Jul; 29(6-7):567-9.
  21. Taimouri V, Akhondi-Asl A, Tomas-Fernandez X, Peters JM, Prabhu SP, Poduri A, Takeoka M, Loddenkemper T, Bergin AM, Harini C, Madsen JR, Warfield SK. Electrode localization for planning surgical resection of the epileptogenic zone in pediatric epilepsy. Int J Comput Assist Radiol Surg. 2014 Jan; 9(1):91-105.
  22. Peters JM, Taquet M, Vega C, Jeste SS, Fernández IS, Tan J, Nelson CA, Sahin M, Warfield SK. Brain functional networks in syndromic and non-syndromic autism: a graph theoretical study of EEG connectivity. BMC Med. 2013; 11:54.
  23. Weisenfeld NI, Peters JM, Tsai PT, Prabhu SP, Dies KA, Sahin M, Warfield SK. A magnetic resonance imaging study of cerebellar volume in tuberous sclerosis complex. Pediatr Neurol. 2013 Feb; 48(2):105-10.
  24. Chavakula V, Sánchez Fernández I, Peters JM, Popli G, Bosl W, Rakhade S, Rotenberg A, Loddenkemper T. Automated quantification of spikes. Epilepsy Behav. 2013 Feb; 26(2):143-52.
  25. Akhondi-Asl A, Hans A, Scherrer B, Peters JM, Warfield SK. Whole Brain Group Network Analysis Using Network Bias and Variance Parameters. 2012; (in press):Proc IEEE Int Conf Biom Imag.
  26. Sánchez Fernández I, Loddenkemper T, Peters JM, Kothare SV. Electrical status epilepticus in sleep: clinical presentation and pathophysiology. Pediatr Neurol. 2012 Dec; 47(6):390-410.
  27. Fernández IS, Chapman KE, Peters JM, Kothare SV, Nordli DR, Jensen FE, Berg AT, Loddenkemper T. The tower of Babel: survey on concepts and terminology in electrical status epilepticus in sleep and continuous spikes and waves during sleep in North America. Epilepsia. 2013 Apr; 54(4):741-50.
  28. Lewis WW, Sahin M, Scherrer B, Peters JM, Suarez RO, Vogel-Farley VK, Jeste SS, Gregas MC, Prabhu SP, Nelson CA, Warfield SK. Impaired language pathways in tuberous sclerosis complex patients with autism spectrum disorders. Cereb Cortex. 2013 Jul; 23(7):1526-32.
  29. Fernández IS, Peters JM, Hadjiloizou S, Prabhu SP, Zarowski M, Stannard KM, Takeoka M, Rotenberg A, Kothare SV, Loddenkemper T. Clinical staging and electroencephalographic evolution of continuous spikes and waves during sleep. Epilepsia. 2012 Jul; 53(7):1185-95.
  30. Sánchez Fernández I, Hadjiloizou S, Eksioglu Y, Peters JM, Takeoka M, Tas E, Abdelmoumen I, Rotenberg A, Kothare SV, Riviello JJ, Loddenkemper T. Short-term response of sleep-potentiated spiking to high-dose diazepam in electric status epilepticus during sleep. Pediatr Neurol. 2012 May; 46(5):312-8.
  31. Sánchez Fernández I, Takeoka M, Tas E, Peters JM, Prabhu SP, Stannard KM, Gregas M, Eksioglu Y, Rotenberg A, Riviello JJ, Kothare SV, Loddenkemper T. Early thalamic lesions in patients with sleep-potentiated epileptiform activity. Neurology. 2012 May 29; 78(22):1721-7.
  32. Fernández IS, Peters J, Takeoka M, Rotenberg A, Prabhu S, Gregas M, Riviello JJ, Kothare S, Loddenkemper T. Patients with electrical status epilepticus in sleep share similar clinical features regardless of their focal or generalized sleep potentiation of epileptiform activity. J Child Neurol. 2013 Jan; 28(1):83-9.
  33. Peters JM, Tomas-Fernandez M, van Putten MJ, Loddenkemper T. Behavioral measures and EEG monitoring using the Brain Symmetry Index during the Wada test in children. Epilepsy Behav. 2012 Mar; 23(3):247-53.
  34. Peters JM, Madhavan VL, Kazacos KR, Husson RN, Dangoudoubiyam S, Soul JS. Good outcome with early empiric treatment of neural larva migrans due to Baylisascaris procyonis. Pediatrics. 2012 Mar; 129(3):e806-11.
  35. Taquet M, Scherrer B, Commowick O, Peters J, Sahin M, Macq B, Warfield SK. Registration and analysis of white matter group differences with a multi-fiber model. Med Image Comput Comput Assist Interv. 2012; 15(Pt 3):313-20.
  36. Peters JM, Sahin M, Vogel-Farley VK, Jeste SS, Nelson CA, Gregas MC, Prabhu SP, Scherrer B, Warfield SK. Loss of white matter microstructural integrity is associated with adverse neurological outcome in tuberous sclerosis complex. Acad Radiol. 2012 Jan; 19(1):17-25.
  37. Kelly TG, Madhavan VL, Peters JM, Kazacos KR, Silvera VM. Spinal cord involvement in a child with raccoon roundworm (Baylisascaris procyonis) meningoencephalitis. Pediatr Radiol. 2012 Mar; 42(3):369-73.
  38. Loddenkemper T, Fernández IS, Peters JM. Continuous spike and waves during sleep and electrical status epilepticus in sleep. J Clin Neurophysiol. 2011 Apr; 28(2):154-64.
  39. Pier DB, Hallbergson A, Peters JM. Guillain-Barré syndrome in a child with pain: lessons learned from a late diagnosis. Acta Paediatr. 2010 Oct; 99(10):1589-91.
  40. Depositario-Cabacar DT, Peters JM, Pong AW, Roth J, Rotenberg A, Riviello JJ, Takeoka M. High-dose intravenous levetiracetam for acute seizure exacerbation in children with intractable epilepsy. Epilepsia. 2010 Jul; 51(7):1319-22.
  41. Peters JM, Maclean AV, Young GS. Rapid resolution of diffusion weighted MRI abnormality in a patient with a stuttering stroke. BMJ Case Rep. 2010; 2010.
  42. Sánchez Fernández I, Peters JM. Picture of the month--quiz case. Moyamoya disease. Arch Pediatr Adolesc Med. 2009 Feb; 163(2):179-80.
  43. Kingma R, Peters JM, Coene LN. Intracranial penetration of a halo pin causing an epileptic seizure. J Bone Joint Surg Br. 2006 Dec; 88(12):1654-5.
  44. Peters JM, Padberg M, Nederveen PJ, Tavy DL, van Putten MJAM. Tijdschr Neurol Neurochir. Neuromonitoring met on-line qEEG tijdens carotisendarteriectomie: ervaringen met de Brain Symmetry Index. 2005; 106(4):143-150.
  45. van Putten MJ, Peters JM, Mulder SM, de Haas JA, Bruijninckx CM, Tavy DL. A brain symmetry index (BSI) for online EEG monitoring in carotid endarterectomy. Clin Neurophysiol. 2004 May; 115(5):1189-94.
  46. Peters JM, Waber DP, McAnulty GB, Duffy FH. Event-related correlations in learning impaired children during A hybrid go/no-go choice reaction visual-motor task. Clin Electroencephalogr. 2003 Jul; 34(3):99-109.
  47. Peters JM, Vriens EM, Stam CJ. Tijdschr Neurol Neurochir. Continue EEG-monitoring op de intensive care. 2003; 104(5):276-282.
  48. Peters JM, Camfield CS, Camfield PR. Population study of benign rolandic epilepsy: is treatment needed? Neurology. 2001 Aug 14; 57(3):537-9.
To schedule an appointment: Call 617-355-5606 or Request an Appointment

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