Jane O'Brien, MD

Associate in Medicine

Assistant Professor of Pediatrics, Harvard Medical School

    Contact: 617-355-6162
  • Fax: Fax: 617-730-0621

Medical Services


  • Autism and Pervasive Developmental Disorders
  • Genetic Diseases and Disorders


  • General Pediatrics


  • Complex Care Services
To schedule an appointment: Call 617-355-6162

Experience and Education



Radcliffe College, 1972

Cambridge, MA

Medical School

Tufts Medical School, 1979

Boston, MA


Boston Floating Hospital - New England Medical Center, 1984

Boston, MA


Boston Floating Hospital - New England Medical Center, 1982

Boston, MA


  • American Board of Medical Genetics and Genomics, Clinical Genetics and Genomics

  • American Board of Pediatrics


Publications powered by Harvard Catalyst Profiles
  1. O'Brien JE, Dumas HM, Fragala-Pinkham MA, Berry JG. Admissions to Acute Care Within 30 and 90 Days of Discharge Home From a Pediatric Post-acute Care Hospital. Hosp Pediatr. 2017 Nov; 7(11):682-685.
  2. Dumas HM, Fragala-Pinkham MA, Rosen EL, O'Brien JE. Construct validity of the pediatric evaluation of disability inventory computer adaptive test (PEDI-CAT) in children with medical complexity. Disabil Rehabil. 2017 Nov; 39(23):2446-2451.
  3. Fragala-Pinkham MA, Dumas HM, Lombard KA, O'Brien JE. Responsiveness of the Pediatric Evaluation of Disability Inventory-Computer Adaptive Test in measuring functional outcomes for inpatient pediatric rehabilitation. J Pediatr Rehabil Med. 2016 09 02; 9(3):215-22.
  4. Place AE, Stevenson KE, Vrooman LM, Harris MH, Hunt SK, O'Brien JE, Supko JG, Asselin BL, Athale UH, Clavell LA, Cole PD, Kelly KM, Laverdiere C, Leclerc JM, Michon B, Schorin MA, Welch JJ, Lipshultz SE, Kutok JL, Blonquist TM, Neuberg DS, Sallan SE, Silverman LB. Intravenous pegylated asparaginase versus intramuscular native Escherichia coli L-asparaginase in newly diagnosed childhood acute lymphoblastic leukaemia (DFCI 05-001): a randomised, open-label phase 3 trial. Lancet Oncol. 2015 Dec; 16(16):1677-90.
  5. O'Brien JE, Dumas HM. Development and Initial Psychometric Evaluation of the Post-Acute Acuity Rating for Children. Rehabil Res Pract. 2015; 2015:841523.
  6. O'Brien JE, Berry J, Dumas H. Pediatric Post-Acute Hospital Care: Striving for Identity and Value. Hosp Pediatr. 2015 Oct; 5(10):548-51.
  7. O'Brien JE, Dumas HM, Nash CM, Mekary R. Unplanned readmissions to acute care from a pediatric postacute care hospital: incidence, clinical reasons, and predictive factors. Hosp Pediatr. 2015 Mar; 5(3):134-40.
  8. O'Brien JE, Dumas HM, Leslie D. Neonatal abstinence outcomes in post-acute care: A brief report. J Pediatr Rehabil Med. 2015; 8(2):157-60.
  9. O'Brien JE, Dumas HM, Nash CM, Burke SA, Holson DC, Mast J, Pelegano J, Simpser EF, Traul C, Whitford K. Pediatric post-acute care hospital transitions: an evaluation of current practice. Hosp Pediatr. 2014 Jul; 4(4):217-21.
  10. Estacion M, O'Brien JE, Conravey A, Hammer MF, Waxman SG, Dib-Hajj SD, Meisler MH. A novel de novo mutation of SCN8A (Nav1.6) with enhanced channel activation in a child with epileptic encephalopathy. Neurobiol Dis. 2014 Sep; 69:117-23.
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  12. O'Brien JE, Dumas HM. Hospital length of stay, discharge disposition, and reimbursement by clinical program group in pediatric post-acute rehabilitation. J Pediatr Rehabil Med. 2013; 6(1):29-34.
  13. Dumas HM, Rosen EL, Haley SM, Fragala-Pinkham MA, Ni P, O'Brien JE. Measuring physical function in children with airway support: a pilot study using computer adaptive testing. Dev Neurorehabil. 2010; 13(2):95-102.
  14. Silverman LB, Supko JG, Stevenson KE, Woodward C, Vrooman LM, Neuberg DS, Asselin BL, Athale UH, Clavell L, Cole PD, Kelly KM, Laverdière C, Michon B, Schorin M, Schwartz CL, O'Brien JE, Cohen HJ, Sallan SE. Intravenous PEG-asparaginase during remission induction in children and adolescents with newly diagnosed acute lymphoblastic leukemia. Blood. 2010 Feb 18; 115(7):1351-3.
  15. Berry JG, Graham DA, Graham RJ, Zhou J, Putney HL, O'Brien JE, Roberson DW, Goldmann DA. Predictors of clinical outcomes and hospital resource use of children after tracheotomy. Pediatrics. 2009 Aug; 124(2):563-72.
  16. O'Brien JE, Dumas HM, Haley SM, Peters CY. Development and evaluation of a minimum data set for children with airway support for transfers between acute and post-acute care. Dev Neurorehabil. 2009 Jun; 12(3):158-63.
  17. Kharasch VS, Dumas HM, Haley SM, Sawicki GS, Ludlow LH, Wright EA, Jones DT, O'Brien JE. Bronchoscopy findings in children and young adults with tracheostomy due to congenital anomalies and neurological impairment. J Pediatr Rehabil Med. 2008; 1(2):137-43.
  18. O'Brien JE, Haley SM, Dumas HM, Ladenheim B, Mast J, Burke SA, Birnkrant DJ, Whitford K, Coletti DJ, Simpser EF, Pelegano J, Neufeld JA, Kharasch VS. Outcomes of post-acute hospital episodes for young children requiring airway support. Dev Neurorehabil. 2007 Jul-Sep; 10(3):241-7.
  19. O'Brien JE, Dumas HM, Haley SM, Ladenheim B, Mast J, Burke SA, Birnkrant DJ, Whitford K, Palazzo R, Neufeld JA, Kharasch VS. Ventilator weaning outcomes in chronic respiratory failure in children. Int J Rehabil Res. 2007 Jun; 30(2):171-4.
  20. O'Brien JE, Birnkrant DJ, Dumas HM, Haley SM, Burke SA, Graham RJ, Kharasch VS. Weaning children from mechanical ventilation in a post-acute care setting. Pediatr Rehabil. 2006 Oct-Dec; 9(4):365-72.
  21. Graham RJ, Dumas HM, O'Brien JE, Burns JP. Congenital neurodevelopmental diagnoses and an intensive care unit: defining a population. Pediatr Crit Care Med. 2004 Jul; 5(4):321-8.
  22. Kharasch VS, Haley SM, Dumas HM, Ludlow LH, O'Brien JE. Oxygen and ventilator weaning during inpatient pediatric pulmonary rehabilitation. Pediatr Pulmonol. 2003 Apr; 35(4):280-7.
  23. Cushman DG, Dumas HM, Haley SM, O'Brien JE, Kharasch VS. Re-admissions to inpatient paediatric pulmonary rehabilitation. Pediatr Rehabil. 2002 Jul-Sep; 5(3):133-9.
  24. O'Brien JE, Dumas HM, Haley SM, O'Neil ME, Renn M, Bartolacci TE, Kharasch V. Clinical findings and resource use of infants and toddlers dependent on oxygen and ventilators. Clin Pediatr (Phila). 2002 Apr; 41(3):155-62.
To schedule an appointment: Call 617-355-6162


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