Francis Fynn-Thompson

Francis Fynn-Thompson, MD

Surgical Director, Ventricular Assist Device Program; Surgical Director, Lung Transplant Program; Surgical Director, Heart Transplant Program; Associate in Cardiac Surgery

Assistant Professor of Surgery, Harvard Medical School

Medical Services


  • Heart Lung Transplantation
  • Minimally Invasive Surgery
  • Ventricular Assist Devices
  • Cardiovascular Surgery


  • Cardiac Surgery
  • Cardiovascular Program


  • Lung Transplant Program
  • Heart Transplant Program
  • Cardiac Surgery Program
  • Ventricular Assist Device (VAD) Program
To schedule an appointment: Call 617-355-6712 or Request an Appointment

Experience and Education



University of Pennsylvania, 1993

Philadelphia, PA

Medical School

Harvard Medical School, 1997

Boston, MA


Massachusetts General Hospital, 1997-1998

Boston, MA


Massachusetts General Hospital, 1998-2002

Boston, MA


Boston Children's Hospital, 2003-2004

Boston, MA


  • Surgery, Thoracic Surgery

  • Congenital Cardiac Surgery


Dr. Fynn-Thompson's research activities are focused on clinical and translational projects, primarily with regard to minimally invasive techniques and arrhythmia surgery.



Publications powered by Harvard Catalyst Profiles
  1. Faella KH, Whiting D, Fynn-Thompson F, Matte GS. Bivalirudin Anticoagulation for a Pediatric Patient with Heparin-Induced Thrombocytopenia and Thrombosis Requiring Cardiopulmonary Bypass for Ventricular Assist Device Placement. J Extra Corpor Technol. 2016 Mar; 48(1):39-42.
  2. Matte GS, Connor KR, Toutenel NA, Gottlieb D, Fynn-Thompson F. A Modified EXIT-to-ECMO with Optional Reservoir Circuit for Use during an EXIT Procedure Requiring Thoracic Surgery. J Extra Corpor Technol. 2016 Mar; 48(1):35-8.
  3. Visner GA, Fynn-Thompson F. Paracorporeal lung assist device in infants and toddlers: Coming of age? Pediatr Transplant. 2016 Mar; 20(2):191-3.
  4. Hofferberth SC, Watters K, Rahbar R, Fynn-Thompson F. Evolution of Surgical Approaches in the Management of Congenital Tracheal Stenosis: Single-Center Experience. World J Pediatr Congenit Heart Surg. 2016 Jan; 7(1):16-24.
  5. Hofferberth SC, Watters K, Rahbar R, Fynn-Thompson F. Management of Congenital Tracheal Stenosis. Pediatrics. 2015 Sep; 136(3):e660-9.
  6. Hofferberth SC, Alexander ME, Mah DY, Bautista-Hernandez V, del Nido PJ, Fynn-Thompson F. Impact of pacing on systemic ventricular function in L-transposition of the great arteries. J Thorac Cardiovasc Surg. 2016 Jan; 151(1):131-8.
  7. Quinonez LG, Gauvreau K, Borisuk M, Ireland C, Marshall AM, Mayer JE, Jenkins KJ, Fynn-Thompson FE, Baird CW. Outcomes of surgery for young children with multivessel pulmonary vein stenosis. J Thorac Cardiovasc Surg. 2015 Oct; 150(4):911-7.
  8. Stock C, Nathan M, Murray R, Rahbar R, Fynn-Thompson F. Modified end-to-end anastomosis for the treatment of congenital tracheal stenosis with a bridging bronchus. Ann Thorac Surg. 2015 Jan; 99(1):346-8.
  9. Nathan M, Marshall AC, Kerstein J, Liu H, Fynn-Thompson F, Baird CW, Mayer JE, Pigula FA, del Nido PJ, Emani S. Technical performance score as predictor for post-discharge reintervention in valve-sparing tetralogy of Fallot repair. Semin Thorac Cardiovasc Surg. 2014; 26(4):297-303.
  10. Balkin EM, Wolfe J, Ziniel SI, Lang P, Thiagarajan R, Dillis S, Fynn-Thompson F, Blume ED. Physician and parent perceptions of prognosis and end-of-life experience in children with advanced heart disease. J Palliat Med. 2015 Apr; 18(4):318-23.
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  12. Yankah C, Fynn-Thompson F, Antunes M, Edwin F, Yuko-Jowi C, Mendis S, Thameur H, Urban A, Bolman R. Cardiac surgery capacity in sub-saharan Africa: quo vadis? Thorac Cardiovasc Surg. 2014 Aug; 62(5):393-401.
  13. Emani S, Trainor B, Zurakowski D, Baird CW, Fynn-Thompson FE, Pigula FA, Emani SM. Aspirin unresponsiveness predicts thrombosis in high-risk pediatric patients after cardiac surgery. J Thorac Cardiovasc Surg. 2014 Sep; 148(3):810-4; discussion 814-6.
  14. Teele SA, Salvin JW, Barrett CS, Rycus PT, Fynn-Thompson F, Laussen PC, Thiagarajan RR. The association of carotid artery cannulation and neurologic injury in pediatric patients supported with venoarterial extracorporeal membrane oxygenation*. Pediatr Crit Care Med. 2014 May; 15(4):355-61.
  15. Vanderpluym CJ, Fynn-Thompson F, Blume ED. Ventricular assist devices in children: progress with an orphan device application. Circulation. 2014 Apr 8; 129(14):1530-7.
  16. Escobar-Diaz MC, Tworetzky W, Friedman K, Lafranchi T, Fynn-Thompson F, Alexander ME, Mah DY. Perinatal outcome in fetuses with heterotaxy syndrome and atrioventricular block or bradycardia. Pediatr Cardiol. 2014 Aug; 35(6):906-13.
  17. Restrepo M, Mirabella L, Tang E, Haggerty CM, Khiabani RH, Fynn-Thompson F, Valente AM, McElhinney DB, Fogel MA, Yoganathan AP. Fontan pathway growth: a quantitative evaluation of lateral tunnel and extracardiac cavopulmonary connections using serial cardiac magnetic resonance. Ann Thorac Surg. 2014 Mar; 97(3):916-22.
  18. Weinstein S, Bello R, Pizarro C, Fynn-Thompson F, Kirklin J, Guleserian K, Woods R, Tjossem C, Kroslowitz R, Friedmann P, Jaquiss R. The use of the Berlin Heart EXCOR in patients with functional single ventricle. J Thorac Cardiovasc Surg. 2014 Feb; 147(2):697-704; discussion 704-5.
  19. Hofferberth SC, Cecchin F, Loberman D, Fynn-Thompson F. Left thoracoscopic sympathectomy for cardiac denervation in patients with life-threatening ventricular arrhythmias. J Thorac Cardiovasc Surg. 2014 Jan; 147(1):404-9.
  20. Nathan M, Karamichalis J, Liu H, Gauvreau K, Colan S, Saia M, Pigula F, Fynn-Thompson F, Emani S, Baird C, Mayer JE, del Nido PJ. Technical Performance Scores are strongly associated with early mortality, postoperative adverse events, and intensive care unit length of stay-analysis of consecutive discharges for 2 years. J Thorac Cardiovasc Surg. 2014 Jan; 147(1):389-94, 396.e1-396.e3.
  21. Mah DY, Alexander ME, Banka P, Abrams DJ, Triedman JK, Walsh EP, Fynn-Thompson F, Mayer JE, Cecchin F. The role of cardiac resynchronization therapy for arterial switch operations complicated by complete heart block. Ann Thorac Surg. 2013 Sep; 96(3):904-9.
  22. Daly KP, Chandler SF, Almond CS, Singh TP, Mah H, Milford E, Matte GS, Bastardi HJ, Mayer JE, Fynn-Thompson F, Blume ED. Antibody depletion for the treatment of crossmatch-positive pediatric heart transplant recipients. Pediatr Transplant. 2013 Nov; 17(7):661-9.
  23. Allan CK, Pigula F, Bacha EA, Emani S, Fynn-Thompson F, Thiagarajan RR, Imprescia A, Hayes G, Weinstock P. An extracorporeal membrane oxygenation cannulation curriculum featuring a novel integrated skills trainer leads to improved performance among pediatric cardiac surgery trainees. Simul Healthc. 2013 Aug; 8(4):221-8.
  24. Nathan M, Pigula FA, Liu H, Gauvreau K, Colan SD, Fynn-Thompson F, Emani S, Baird CA, Mayer JE, Del Nido PJ. Inadequate technical performance scores are associated with late mortality and late reintervention. Ann Thorac Surg. 2013 Aug; 96(2):664-9.
  25. Nathan M, Liu H, Pigula FA, Fynn-Thompson F, Emani S, Baird CA, Marx G, Mayer JE, Del Nido PJ. Biventricular conversion after single-ventricle palliation in unbalanced atrioventricular canal defects. Ann Thorac Surg. 2013 Jun; 95(6):2086-95; discussion 2095-6.
  26. Karamichalis JM, Colan SD, Nathan M, Pigula FA, Baird C, Marx G, Emani SM, Geva T, Fynn-Thompson FE, Liu H, Mayer JE, del Nido PJ. Technical performance scores in congenital cardiac operations: a quality assessment initiative. Ann Thorac Surg. 2012 Oct; 94(4):1317-23; discussion 1323.
  27. Costello JM, O'Brien M, Wypij D, Shubert J, Salvin JW, Newburger JW, Laussen PC, Arnold JH, Fynn-Thompson F, Thiagarajan RR. Quality of life of pediatric cardiac patients who previously required extracorporeal membrane oxygenation. Pediatr Crit Care Med. 2012 Jul; 13(4):428-34.
  28. Sherwin ED, Gauvreau K, Scheurer MA, Rycus PT, Salvin JW, Almodovar MC, Fynn-Thompson F, Thiagarajan RR. Extracorporeal membrane oxygenation after stage 1 palliation for hypoplastic left heart syndrome. J Thorac Cardiovasc Surg. 2012 Dec; 144(6):1337-43.
  29. Haggerty CM, Fynn-Thompson F, McElhinney DB, Valente AM, Saikrishnan N, Del Nido PJ, Yoganathan AP. Experimental and numeric investigation of Impella pumps as cavopulmonary assistance for a failing Fontan. J Thorac Cardiovasc Surg. 2012 Sep; 144(3):563-9.
  30. Kovach JR, Naftel DC, Pearce FB, Tresler MA, Edens RE, Shuhaiber JH, Blume ED, Fynn-Thompson F, Kirklin JK, Zangwill SD. Comparison of risk factors and outcomes for pediatric patients listed for heart transplantation after bidirectional Glenn and after Fontan: an analysis from the Pediatric Heart Transplant Study. J Heart Lung Transplant. 2012 Feb; 31(2):133-9.
  31. Betit P, Matte GS, Howe R, Iudiciani P, Barrett C, Thiagarajan R, Fynn-Thompson F. The addition of a membrane oxygenator to a ventricular assist device in a patient with acute respiratory distress syndrome. J Extra Corpor Technol. 2011 Dec; 43(4):264-6.
  32. Bautista-Hernandez V, Sanchez-Andres A, Portela F, Fynn-Thompson F. Current pharmacologic management of pediatric heart failure in congenital heart disease. Curr Vasc Pharmacol. 2011 Sep; 9(5):619-28.
  33. Karamanlidis G, Bautista-Hernandez V, Fynn-Thompson F, Del Nido P, Tian R. Impaired mitochondrial biogenesis precedes heart failure in right ventricular hypertrophy in congenital heart disease. Circ Heart Fail. 2011 Nov; 4(6):707-13.
  34. Karamichalis JM, del Nido PJ, Thiagarajan RR, Jenkins KJ, Liu H, Gauvreau K, Pigula FA, Fynn-Thompson FE, Emani SM, Mayer JE, Bacha EA. Early postoperative severity of illness predicts outcomes after the stage I Norwood procedure. Ann Thorac Surg. 2011 Aug; 92(2):660-5.
  35. Ford MA, Almond CS, Gauvreau K, Piercey G, Blume ED, Smoot LB, Fynn-Thompson F, Singh TP. Association of graft ischemic time with survival after heart transplant among children in the United States. J Heart Lung Transplant. 2011 Nov; 30(11):1244-9.
  36. Almond CS, Singh TP, Gauvreau K, Piercey GE, Fynn-Thompson F, Rycus PT, Bartlett RH, Thiagarajan RR. Extracorporeal membrane oxygenation for bridge to heart transplantation among children in the United States: analysis of data from the Organ Procurement and Transplant Network and Extracorporeal Life Support Organization Registry. Circulation. 2011 Jun 28; 123(25):2975-84.
  37. Shuhaiber J, Thiagarajan RR, Laussen PC, Fynn-Thompson F, del Nido P, Pigula F. Survival of children requiring repeat extracorporeal membrane oxygenation after congenital heart surgery. Ann Thorac Surg. 2011 Jun; 91(6):1949-55.
  38. Shuhaiber J, Rehman M, Jenkins K, Fynn-Thompson F, Bacha E. The role of surgical therapy for pulmonary vein atresia in childhood. Pediatr Cardiol. 2011 Jun; 32(5):639-45.
  39. Rood KL, Teele SA, Barrett CS, Salvin JW, Rycus PT, Fynn-Thompson F, Laussen PC, Thiagarajan RR. Extracorporeal membrane oxygenation support after the Fontan operation. J Thorac Cardiovasc Surg. 2011 Sep; 142(3):504-10.
  40. Morales DL, Almond CS, Jaquiss RD, Rosenthal DN, Naftel DC, Massicotte MP, Humpl T, Turrentine MW, Tweddell JS, Cohen GA, Kroslowitz R, Devaney EJ, Canter CE, Fynn-Thompson F, Reinhartz O, Imamura M, Ghanayem NS, Buchholz H, Furness S, Mazor R, Gandhi SK, Fraser CD. Bridging children of all sizes to cardiac transplantation: the initial multicenter North American experience with the Berlin Heart EXCOR ventricular assist device. J Heart Lung Transplant. 2011 Jan; 30(1):1-8.
  41. Bautista-Hernandez V, Scheurer M, Thiagarajan R, Salvin J, Pigula FA, Emani S, Fynn-Thompson F, Loyola H, Schiff J, del Nido PJ, Bacha EA. Right ventricle and tricuspid valve function at midterm after the Fontan operation for hypoplastic left heart syndrome: impact of shunt type. Pediatr Cardiol. 2011 Feb; 32(2):160-6.
  42. Goldfarb SB, Gaynor JW, Fuller S, Kreindler J, Montenegro LM, Fynn-Thompson F, Visner G. Induction therapy with antithymocyte globulin before reperfusion. Ann Thorac Surg. 2010 Oct; 90(4):1110-4; discussion 1114-5.
  43. Kane DA, Thiagarajan RR, Wypij D, Scheurer MA, Fynn-Thompson F, Emani S, del Nido PJ, Betit P, Laussen PC. Rapid-response extracorporeal membrane oxygenation to support cardiopulmonary resuscitation in children with cardiac disease. Circulation. 2010 Sep 14; 122(11 Suppl):S241-8.
  44. Silva JN, Canter CE, Singh TP, Gauvreau K, Piercey GE, Berul CI, Smoot LB, Blume ED, Fynn-Thompson F, Almond CS. Outcomes of heart transplantation using donor hearts from infants with sudden infant death syndrome. J Heart Lung Transplant. 2010 Nov; 29(11):1226-30.
  45. Shuhaiber JH, Bergersen L, Pigula F, Emani S, McElhinney D, Marshall A, Fynn-Thompson F, Bacha EA. Intraoperative assessment after pediatric cardiac surgical repair: initial experience with C-arm angiography. J Thorac Cardiovasc Surg. 2010 Jul; 140(1):e1-3.
  46. Almond CS, Gauvreau K, Thiagarajan RR, Piercey GE, Blume ED, Smoot LB, Fynn-Thompson F, Singh TP. Impact of ABO-incompatible listing on wait-list outcomes among infants listed for heart transplantation in the United States: a propensity analysis. Circulation. 2010 May 4; 121(17):1926-33.
  47. Radbill AE, Triedman JK, Berul CI, Fynn-Thompson F, Atallah J, Alexander ME, Walsh EP, Cecchin F. System survival of nontransvenous implantable cardioverter-defibrillators compared to transvenous implantable cardioverter-defibrillators in pediatric and congenital heart disease patients. Heart Rhythm. 2010; 7(2):193-8.
  48. Bautista-Hernandez V, Thiagarajan RR, Fynn-Thompson F, Rajagopal SK, Nento DE, Yarlagadda V, Teele SA, Allan CK, Emani SM, Laussen PC, Pigula FA, Bacha EA. Preoperative extracorporeal membrane oxygenation as a bridge to cardiac surgery in children with congenital heart disease. Ann Thorac Surg. 2009 Oct; 88(4):1306-11.
  49. Mah D, Singh TP, Thiagarajan RR, Gauvreau K, Piercey GE, Blume ED, Fynn-Thompson F, Almond CS. Incidence and risk factors for mortality in infants awaiting heart transplantation in the USA. J Heart Lung Transplant. 2009 Dec; 28(12):1292-8.
  50. Kaza AK, Lim HG, Dibardino DJ, Bautista-Hernandez V, Robinson J, Allan C, Laussen P, Fynn-Thompson F, Bacha E, del Nido PJ, Mayer JE, Pigula FA. Long-term results of right ventricular outflow tract reconstruction in neonatal cardiac surgery: options and outcomes. J Thorac Cardiovasc Surg. 2009 Oct; 138(4):911-6.
  51. Takahashi K, Cecchin F, Fortescue E, Berul CI, Alexander ME, Walsh EP, Fynn-Thompson F, Triedman JK. Permanent atrial pacing lead implant route after Fontan operation. Pacing Clin Electrophysiol. 2009 Jun; 32(6):779-85.
  52. Lim HG, Bacha EA, Marx GR, Marshall A, Fynn-Thompson F, Mayer JE, Del Nido P, Pigula FA. Biventricular repair in patients with heterotaxy syndrome. J Thorac Cardiovasc Surg. 2009 Feb; 137(2):371-379.e3.
  53. Almond CS, Thiagarajan RR, Piercey GE, Gauvreau K, Blume ED, Bastardi HJ, Fynn-Thompson F, Singh TP. Waiting list mortality among children listed for heart transplantation in the United States. Circulation. 2009 Feb 10; 119(5):717-27.
  54. Atallah J, Fynn-Thompson F, Cecchin F, DiBardino DJ, Walsh EP, Berul CI. Video-assisted thoracoscopic cardiac denervation: a potential novel therapeutic option for children with intractable ventricular arrhythmias. Ann Thorac Surg. 2008 Nov; 86(5):1620-5.
  55. Cecchin F, Frangini PA, Brown DW, Fynn-Thompson F, Alexander ME, Triedman JK, Gauvreau K, Walsh EP, Berul CI. Cardiac resynchronization therapy (and multisite pacing) in pediatrics and congenital heart disease: five years experience in a single institution. J Cardiovasc Electrophysiol. 2009 Jan; 20(1):58-65.
  56. Bacha EA, Larrazabal LA, Pigula FA, Gauvreau K, Jenkins KJ, Colan SD, Fynn-Thompson F, Mayer JE, del Nido PJ. Measurement of technical performance in surgery for congenital heart disease: the stage I Norwood procedure. J Thorac Cardiovasc Surg. 2008 Oct; 136(4):993-7, 997.e1-2.
  57. Takahashi K, Fynn-Thompson F, Cecchin F, Khairy P, del Nido P, Triedman JK. Clinical outcomes of Fontan conversion surgery with and without associated arrhythmia intervention. Int J Cardiol. 2009 Nov 12; 137(3):260-6.
  58. Scheurer MA, Salvin JW, Vida VL, Fynn-Thompson F, Bacha EA, Pigula FA, Mayer JE, del Nido PJ, Wessel DL, Laussen PC, Thiagarajan RR. Survival and clinical course at Fontan after stage one palliation with either a modified Blalock-Taussig shunt or a right ventricle to pulmonary artery conduit. J Am Coll Cardiol. 2008 Jul 1; 52(1):52-9.
  59. Vida VL, Bacha EA, Larrazabal A, Gauvreau K, Dorfman AL, Marx G, Geva T, Marshall AC, Pigula FA, Mayer JE, del Nido PJ, Fynn-Thompson F. Surgical outcome for patients with the mitral stenosis-aortic atresia variant of hypoplastic left heart syndrome. J Thorac Cardiovasc Surg. 2008 Feb; 135(2):339-46.
  60. Vida VL, Bacha EA, Larrazabal A, Gauvreau K, Thiagaragan R, Fynn-Thompson F, Pigula FA, Mayer JE, del Nido PJ, Tworetzky W, Lock JE, Marshall AC. Hypoplastic left heart syndrome with intact or highly restrictive atrial septum: surgical experience from a single center. Ann Thorac Surg. 2007 Aug; 84(2):581-5; discussion 586.
  61. Fynn-Thompson F, Almond C. Pediatric ventricular assist devices. Pediatr Cardiol. 2007 Mar-Apr; 28(2):149-55.
  62. Larrazabal LA, del Nido PJ, Jenkins KJ, Gauvreau K, Lacro R, Colan SD, Pigula F, Benavidez OJ, Fynn-Thompson F, Mayer JE, Bacha EA. Measurement of technical performance in congenital heart surgery: a pilot study. Ann Thorac Surg. 2007 Jan; 83(1):179-84.
  63. P. Frangini, F. Cecchin, F. Fynn-Thompson, D. Brown, M. Alexander, J. Triedman, E. Walsh, C. Berul. Cardiac resynchronization therapy is associated with improved systolic ventricular function in pediatrics and congenital heart disease. Heart Rhythm. 2006; 3(5):S172.
  64. Nathan M, Baird C, Fynn-Thompson F, Almond C, Thiagarajan R, Laussen P, Blume E, Pigula F. Successful implantation of a Berlin heart biventricular assist device in a failing single ventricle. J Thorac Cardiovasc Surg. 2006 Jun; 131(6):1407-8.
  65. Christopher Baird, Francis Fynn-Thompson, Meena Nathan, Frank Pigula. Berlin Heart: Biventricular Assist Device. 2005.
  66. Fynn-Thompson F, Vander Salm TJ. Methods for reduction of sternal wound infection. Semin Thorac Cardiovasc Surg. 2004; 16(1):77-80.
  67. Fynn-Thompson, F., Allan, J.,. Management of tracheobronchial and esophageal trauma. The Trauma Handbook of the Massachusetts General Hospital. 2004; 314-327 .
  68. Horiuchi K, Fynn-Thompson F, Ohene-Frempong K. Quantitative analysis of the degree of irreversible deformation of F cells and non-F cells and its relationship to cell density in sickle cell disease. Exp Hematol. 1994 Oct; 22(11):1058-63.
  69. Fynn-Thompson, F.,. Dynamics of Health Care in Ghana: A model for Africa. 1993.
To schedule an appointment: Call 617-355-6712 or Request an Appointment


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