Elizabeth D.  Blume

Elizabeth Blume, MD

Director, Advanced Cardiac Therapies; Medical Director, Heart Transplant Program; Medical Director, Heart Failure Program

Associate Professor of Pediatrics, Harvard Medical School

Medical Services

Specialties

  • Transplantation
  • Heart Failure
  • Cardiology

Departments

  • Cardiology
  • Cardiovascular Program

Programs

  • Heart Transplant Program
  • Ventricular Assist Device (VAD) Program
  • Cardiomyopathy Program
  • Heart Failure Program
To schedule an appointment: Call 617-355-6329 or Request an Appointment

Experience and Education

Education

Medical School

Case Western Reserve University, 1991

Cleveland, OH

Residency

Boston Children's Hospital, 07/93 to 06/94

Boston, MA

Undergraduate School

Brown University, 1986

Providence, RI

Fellowship

Boston Children's Hospital, 07/94 to 08/97

Boston, MA

Certifications

  • Pediatrics, Pediatric Cardiology

Research

Dr. Blume’s research is focused on the treatment of end-stage heart disease and heart transplantation in pediatric patients.

View Dr. Blume’s research profile

Publications

Publications powered by Harvard Catalyst Profiles
  1. Kirkpatrick JN, Hauptman PJ, Swetz KM, Blume ED, Gauvreau K, Maurer M, Goodlin SJ. Palliative Care for Patients With End-Stage Cardiovascular Disease and Devices: A Report From the Palliative Care Working Group of the Geriatrics Section of the American College of Cardiology. JAMA Intern Med. 2016 Jul 1; 176(7):1017-9.
  2. Mills KI, Vincent JA, Zuckerman WA, Hoffman TM, Canter CE, Marshall AC, Blume ED, Bergersen L, Daly KP. Is Endomyocardial Biopsy a Safe and Useful Procedure in Children with Suspected Cardiomyopathy? Pediatr Cardiol. 2016 Oct; 37(7):1200-10.
  3. Pasquali SK, Jacobs JP, Farber GK, Bertoch D, Blume ED, Burns KM, Campbell R, Chang AC, Chung WK, Riehle-Colarusso T, Curtis LH, Forrest CB, Gaynor WJ, Gaies MG, Go AS, Henchey P, Martin GR, Pearson G, Pemberton VL, Schwartz SM, Vincent R, Kaltman JR. Report of the National Heart, Lung, and Blood Institute Working Group: An Integrated Network for Congenital Heart Disease Research. Circulation. 2016 Apr 5; 133(14):1410-8.
  4. Blume ED, Rosenthal DN, Rossano JW, Baldwin JT, Eghtesady P, Morales DL, Cantor RS, Conway J, Lorts A, Almond CS, Naftel DC, Kirklin JK. Outcomes of children implanted with ventricular assist devices in the United States: First analysis of the Pediatric Interagency Registry for Mechanical Circulatory Support (PediMACS). J Heart Lung Transplant. 2016 May; 35(5):578-84.
  5. Rossano JW, Lorts A, VanderPluym CJ, Jeewa A, Guleserian KJ, Bleiweis MS, Reinhartz O, Blume ED, Rosenthal DN, Naftel DC, Cantor RS, Kirklin JK. Outcomes of pediatric patients supported with continuous-flow ventricular assist devices: A report from the Pediatric Interagency Registry for Mechanical Circulatory Support (PediMACS). J Heart Lung Transplant. 2016 May; 35(5):585-90.
  6. Garbern JC, Gauvreau K, Blume ED, Singh TP. Is Myocarditis an Independent Risk Factor for Post-Transplant Mortality in Pediatric Heart Transplant Recipients? Circ Heart Fail. 2016 Jan; 9(1):e002328.
  7. Lorts A, Blume ED. Pediatric mechanical circulatory support: available devices and outcomes as bridge-to-transplant therapy. Curr Opin Organ Transplant. 2015 Oct; 20(5):557-61.
  8. Balkin EM, Wolfe J, Ziniel SI, Lang P, Thiagarajan R, Dillis S, Fynn-Thompson F, Blume ED. Physician and parent perceptions of prognosis and end-of-life experience in children with advanced heart disease. J Palliat Med. 2015 Apr; 18(4):318-23.
  9. Reddy S, Fung A, Manlhiot C, Tierney ES, Chung WK, Blume E, Kaufman BD, Goldmuntz E, Colan S, Mital S. Adrenergic receptor genotype influences heart failure severity and ß-blocker response in children with dilated cardiomyopathy. Pediatr Res. 2015 Feb; 77(2):363-9.
  10. Singh TP, Blume ED, Alexander PM, Gauvreau K. Association of hemodynamic profiles with wait-list mortality in children listed for heart transplantation with idiopathic dilated cardiomyopathy. Am J Cardiol. 2015 Jan 15; 115(2):243-8.
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  12. Schoettler M, Elisofon SA, Kim HB, Blume ED, Rodig N, Boyer D, Neufeld EJ, Grace RF. Treatment and outcomes of immune cytopenias following solid organ transplant in children. Pediatr Blood Cancer. 2015 Feb; 62(2):214-218.
  13. Blume ED, Balkin EM, Aiyagari R, Ziniel S, Beke DM, Thiagarajan R, Taylor L, Kulik T, Pituch K, Wolfe J. Parental perspectives on suffering and quality of life at end-of-life in children with advanced heart disease: an exploratory study*. Pediatr Crit Care Med. 2014 May; 15(4):336-42.
  14. Schumacher KR, Singh TP, Kuebler J, Aprile K, O'Brien M, Blume ED. Risk factors and outcome of Fontan-associated plastic bronchitis: a case-control study. J Am Heart Assoc. 2014; 3(2):e000865.
  15. Kirklin JK, Naftel DC, Pagani FD, Kormos RL, Stevenson LW, Blume ED, Miller MA, Baldwin JT, Timothy Baldwin J, Young JB. Sixth INTERMACS annual report: a 10,000-patient database. J Heart Lung Transplant. 2014 Jun; 33(6):555-64.
  16. Vanderpluym CJ, Fynn-Thompson F, Blume ED. Ventricular assist devices in children: progress with an orphan device application. Circulation. 2014 Apr 8; 129(14):1530-7.
  17. VanderPluym C, Graham DA, Almond CS, Blume ED, Milliren CE, Singh TP. Survival in patients removed from the heart transplant waiting list before receiving a transplant. J Heart Lung Transplant. 2014 Mar; 33(3):261-9.
  18. Daly KP, Chandler SF, Almond CS, Singh TP, Mah H, Milford E, Matte GS, Bastardi HJ, Mayer JE, Fynn-Thompson F, Blume ED. Antibody depletion for the treatment of crossmatch-positive pediatric heart transplant recipients. Pediatr Transplant. 2013 Nov; 17(7):661-9.
  19. Lytrivi ID, Blume ED, Rhodes J, Dillis S, Gauvreau K, Singh TP. Prognostic value of exercise testing during heart transplant evaluation in children. Circ Heart Fail. 2013 Jul; 6(4):792-9.
  20. Dipchand AI, Kirk R, Mahle WT, Tresler MA, Naftel DC, Pahl E, Miyamoto SD, Blume E, Guleserian KJ, White-Williams C, Kirklin JK. Ten yr of pediatric heart transplantation: a report from the Pediatric Heart Transplant Study. Pediatr Transplant. 2013 Mar; 17(2):99-111.
  21. Khairy P, Clair M, Fernandes SM, Blume ED, Powell AJ, Newburger JW, Landzberg MJ, Mayer JE. Cardiovascular outcomes after the arterial switch operation for D-transposition of the great arteries. Circulation. 2013 Jan 22; 127(3):331-9.
  22. Acker MA, Pagani FD, Stough WG, Mann DL, Jessup M, Kormos R, Slaughter MS, Baldwin T, Stevenson L, Aaronson KD, Miller L, Naftel D, Yancy C, Rogers J, Teuteberg J, Starling RC, Griffith B, Boyce S, Westaby S, Blume E, Wearden P, Higgins R, Mack M. Statement regarding the pre and post market assessment of durable, implantable ventricular assist devices in the United States. J Heart Lung Transplant. 2012 Dec; 31(12):1241-52.
  23. Acker MA, Pagani FD, Stough WG, Mann DL, Jessup M, Kormos R, Slaughter MS, Baldwin T, Stevenson L, Aaronson KD, Miller L, Naftel D, Yancy C, Rogers J, Teuteberg J, Starling RC, Griffith B, Boyce S, Westaby S, Blume E, Wearden P, Higgins R, Mack M. Statement regarding the pre and post market assessment of durable, implantable ventricular assist devices in the United States. Circ Heart Fail. 2013 Jan; 6(1):e1-e11.
  24. Acker MA, Pagani FD, Stough WG, Mann DL, Jessup M, Kormos R, Slaughter MS, Baldwin T, Stevenson L, Aaronson KD, Miller L, Naftel D, Yancy C, Rogers J, Teuteberg J, Starling RC, Griffith B, Boyce S, Westaby S, Blume E, Wearden P, Higgins R, Mack M. Statement regarding the pre and post market assessment of durable, implantable ventricular assist devices in the United States: executive summary. Ann Thorac Surg. 2012 Dec; 94(6):e163-8.
  25. Acker MA, Pagani FD, Stough WG, Mann DL, Jessup M, Kormos R, Slaughter MS, Baldwin T, Stevenson L, Aaronson KD, Miller L, Naftel D, Yancy C, Rogers J, Teuteberg J, Starling RC, Griffith B, Boyce S, Westaby S, Blume E, Wearden P, Higgins R, Mack M. Statement regarding the pre and post market assessment of durable, implantable ventricular assist devices in the United States. Ann Thorac Surg. 2012 Dec; 94(6):2147-58.
  26. Acker MA, Pagani FD, Stough WG, Mann DL, Jessup M, Kormos R, Slaughter MS, Baldwin T, Stevenson L, Aaronson KD, Miller L, Naftel D, Yancy C, Rogers J, Teuteberg J, Starling RC, Griffith B, Boyce S, Westaby S, Blume E, Wearden P, Higgins R, Mack M. Statement regarding the pre and post market assessment of durable, implantable ventricular assist devices in the United States: executive summary. Circ Heart Fail. 2013 Jan; 6(1):145-50.
  27. Schwenk HT, Vo P, Moffitt K, Kehoe E, Blume E, Sharma T, Khatwa U. Allograft-Transmitted Histoplasma capsulatum Infection in a Solid Organ Transplant Recipient. J Pediatric Infect Dis Soc. 2013 Sep; 2(3):270-3.
  28. Kovach JR, Naftel DC, Pearce FB, Tresler MA, Edens RE, Shuhaiber JH, Blume ED, Fynn-Thompson F, Kirklin JK, Zangwill SD. Comparison of risk factors and outcomes for pediatric patients listed for heart transplantation after bidirectional Glenn and after Fontan: an analysis from the Pediatric Heart Transplant Study. J Heart Lung Transplant. 2012 Feb; 31(2):133-9.
  29. Daly KP, Chakravarti SB, Tresler M, Naftel DC, Blume ED, Dipchand AI, Almond CS. Sudden death after pediatric heart transplantation: analysis of data from the Pediatric Heart Transplant Study Group. J Heart Lung Transplant. 2011 Dec; 30(12):1395-402.
  30. Almond CS, Buchholz H, Massicotte P, Ichord R, Rosenthal DN, Uzark K, Jaquiss RD, Kroslowitz R, Kepler MB, Lobbestael A, Bellinger D, Blume ED, Fraser CD, Bartlett RH, Thiagarajan R, Jenkins K. Berlin Heart EXCOR Pediatric ventricular assist device Investigational Device Exemption study: study design and rationale. Am Heart J. 2011 Sep; 162(3):425-35.e6.
  31. Ford MA, Almond CS, Gauvreau K, Piercey G, Blume ED, Smoot LB, Fynn-Thompson F, Singh TP. Association of graft ischemic time with survival after heart transplant among children in the United States. J Heart Lung Transplant. 2011 Nov; 30(11):1244-9.
  32. Guleserian KJ, Schechtman KB, Zheng J, Edens RE, Jacobs JP, Mahle WT, Emerson SL, Naftel DC, Kirklin JK, Blume ED, Canter CE. Outcomes after listing for primary transplantation for infants with unoperated-on non-hypoplastic left heart syndrome congenital heart disease: a multi-institutional study. J Heart Lung Transplant. 2011 Sep; 30(9):1023-32.
  33. Daly KP, Colan SD, Blume ED, Margossian R, Gauvreau K, Duncan C, Lehmann LE, Chen MH. Changes in echocardiographic measures of systolic and diastolic function in children 1 year after hematopoietic SCT. Bone Marrow Transplant. 2011 Dec; 46(12):1532-9.
  34. Morell E, Cheng H, Scheurer M, Smoot L, Wolfe J, Beke D, Blume E. Patterns of End-of-Life Care in Children with Advanced Heart Disease (747). J Pain Symptom Manage. 2011 Jan; 41(1):301.
  35. Gajarski RJ, Blume ED, Urschel S, Schechtman K, Zheng J, West LJ, Altamirano L, Miyamoto S, Naftel DC, Kirklin JK, Zamberlan MC, Canter CE. Infection and malignancy after pediatric heart transplantation: the role of induction therapy. J Heart Lung Transplant. 2011 Mar; 30(3):299-308.
  36. Everitt MD, Pahl E, Schechtman KB, Zheng J, Ringewald JM, L'ecuyer T, Naftel DC, Kirklin JK, Blume ED, Bullock EA, Canter CE. Rejection with hemodynamic compromise in the current era of pediatric heart transplantation: a multi-institutional study. J Heart Lung Transplant. 2011 Mar; 30(3):282-8.
  37. George JF, Taylor DO, Blume ED, Kirklin JK, Naftel DC, Brown RN, Dipchand AI, McGiffin DC, Pamboukian SV, Tallaj JA. Minimizing infection and rejection death: clues acquired from 19 years of multi-institutional cardiac transplantation data. J Heart Lung Transplant. 2011 Feb; 30(2):151-7.
  38. Singh TP, Naftel DC, Addonizio L, Mahle W, Foushee MT, Zangwill S, Blume ED, Kirklin JK, Singh R, Johnston JK, Chinnock R. Association of race and socioeconomic position with outcomes in pediatric heart transplant recipients. Am J Transplant. 2010 Sep; 10(9):2116-23.
  39. Silva JN, Canter CE, Singh TP, Gauvreau K, Piercey GE, Berul CI, Smoot LB, Blume ED, Fynn-Thompson F, Almond CS. Outcomes of heart transplantation using donor hearts from infants with sudden infant death syndrome. J Heart Lung Transplant. 2010 Nov; 29(11):1226-30.
  40. Auerbach SR, Richmond ME, Lamour JM, Blume ED, Addonizio LJ, Shaddy RE, Mahony L, Pahl E, Hsu DT. BNP levels predict outcome in pediatric heart failure patients: post hoc analysis of the Pediatric Carvedilol Trial. Circ Heart Fail. 2010 Sep; 3(5):606-11.
  41. Almond CS, Gauvreau K, Thiagarajan RR, Piercey GE, Blume ED, Smoot LB, Fynn-Thompson F, Singh TP. Impact of ABO-incompatible listing on wait-list outcomes among infants listed for heart transplantation in the United States: a propensity analysis. Circulation. 2010 May 4; 121(17):1926-33.
  42. Gossett JG, Canter CE, Zheng J, Schechtman K, Blume ED, Rodgers S, Naftel DC, Kirklin JK, Scheel J, Fricker FJ, Kantor P, Pahl E. Decline in rejection in the first year after pediatric cardiac transplantation: a multi-institutional study. J Heart Lung Transplant. 2010 Jun; 29(6):625-32.
  43. Bers MU, Beals LM, Chau C, Satoh K, Blume ED, DeMaso DR, Gonzalez-Heydrich J. Use of a virtual community as a psychosocial support system in pediatric transplantation. Pediatr Transplant. 2010 Mar; 14(2):261-7.
  44. Singh TP, Gauvreau K, Thiagarajan R, Blume ED, Piercey G, Almond CS. Racial and ethnic differences in mortality in children awaiting heart transplant in the United States. Am J Transplant. 2009 Dec; 9(12):2808-15.
  45. Mah D, Singh TP, Thiagarajan RR, Gauvreau K, Piercey GE, Blume ED, Fynn-Thompson F, Almond CS. Incidence and risk factors for mortality in infants awaiting heart transplantation in the USA. J Heart Lung Transplant. 2009 Dec; 28(12):1292-8.
  46. Griffiths ER, Kaza AK, Wyler von Ballmoos MC, Loyola H, Valente AM, Blume ED, del Nido P. Evaluating failing Fontans for heart transplantation: predictors of death. Ann Thorac Surg. 2009 Aug; 88(2):558-63; discussion 563-4.
  47. Singh TP, Gauvreau K, Bastardi HJ, Blume ED, Mayer JE. Socioeconomic position and graft failure in pediatric heart transplant recipients. Circ Heart Fail. 2009 May; 2(3):160-5.
  48. Almond CS, Thiagarajan RR, Piercey GE, Gauvreau K, Blume ED, Bastardi HJ, Fynn-Thompson F, Singh TP. Waiting list mortality among children listed for heart transplantation in the United States. Circulation. 2009 Feb 10; 119(5):717-27.
  49. Holman WL, Kormos RL, Naftel DC, Miller MA, Pagani FD, Blume E, Cleeton T, Koenig SC, Edwards L, Kirklin JK. Predictors of death and transplant in patients with a mechanical circulatory support device: a multi-institutional study. J Heart Lung Transplant. 2009 Jan; 28(1):44-50.
  50. Kipps A, Alexander M, Colan SD, Gauvreau K, Smoot L, Crawford L, Darras BT, Blume ED. The longitudinal course of cardiomyopathy in Friedreich's ataxia during childhood. Pediatr Cardiol. 2009 Apr; 30(3):306-10.
  51. Bastardi HJ, Naftel DC, Webber SA, Dillis S, Kirklin JK, Blume ED. Ventricular assist devices as a bridge to heart transplantation in children. J Cardiovasc Nurs. 2008 Jan-Feb; 23(1):25-9.
  52. Moran AM, Blume ED, Quinn R. Intra-aortic balloon pump use in the failing Fontan circulation. Congenit Heart Dis. 2008 Jan-Feb; 3(1):60-2.
  53. Singh TP, Gauvreau K, Rhodes J, Blume ED. Longitudinal changes in heart rate recovery after maximal exercise in pediatric heart transplant recipients: evidence of autonomic re-innervation? J Heart Lung Transplant. 2007 Dec; 26(12):1306-12.
  54. Shaddy RE, Boucek MM, Hsu DT, Boucek RJ, Canter CE, Mahony L, Ross RD, Pahl E, Blume ED, Dodd DA, Rosenthal DN, Burr J, LaSalle B, Holubkov R, Lukas MA, Tani LY. Carvedilol for children and adolescents with heart failure: a randomized controlled trial. JAMA. 2007 Sep 12; 298(10):1171-9.
  55. Almond CS, Mayer JE, Thiagarajan RR, Blume ED, del Nido PJ, McElhinney DB. Outcome after Fontan failure and takedown to an intermediate palliative circulation. Ann Thorac Surg. 2007 Sep; 84(3):880-7.
  56. Farley LM, DeMaso DR, D'Angelo E, Kinnamon C, Bastardi H, Hill CE, Blume ED, Logan DE. Parenting stress and parental post-traumatic stress disorder in families after pediatric heart transplantation. J Heart Lung Transplant. 2007 Feb; 26(2):120-6.
  57. Canter CE, Shaddy RE, Bernstein D, Hsu DT, Chrisant MR, Kirklin JK, Kanter KR, Higgins RS, Blume ED, Rosenthal DN, Boucek MM, Uzark KC, Friedman AH, Friedman AH, Young JK. Indications for heart transplantation in pediatric heart disease: a scientific statement from the American Heart Association Council on Cardiovascular Disease in the Young; the Councils on Clinical Cardiology, Cardiovascular Nursing, and Cardiovascular Surgery and Anesthesia; and the Quality of Care and Outcomes Research Interdisciplinary Working Group. Circulation. 2007 Feb 6; 115(5):658-76.
  58. Bernstein D, Naftel D, Chin C, Addonizio LJ, Gamberg P, Blume ED, Hsu D, Canter CE, Kirklin JK, Morrow WR. Outcome of listing for cardiac transplantation for failed Fontan: a multi-institutional study. Circulation. 2006 Jul 25; 114(4):273-80.
  59. Nathan M, Baird C, Fynn-Thompson F, Almond C, Thiagarajan R, Laussen P, Blume E, Pigula F. Successful implantation of a Berlin heart biventricular assist device in a failing single ventricle. J Thorac Cardiovasc Surg. 2006 Jun; 131(6):1407-8.
  60. Blume ED, Naftel DC, Bastardi HJ, Duncan BW, Kirklin JK, Webber SA. Outcomes of children bridged to heart transplantation with ventricular assist devices: a multi-institutional study. Circulation. 2006 May 16; 113(19):2313-9.
  61. Blume ED, Canter CE, Spicer R, Gauvreau K, Colan S, Jenkins KJ. Prospective single-arm protocol of carvedilol in children with ventricular dysfunction. Pediatr Cardiol. 2006 May-Jun; 27(3):336-42.
  62. Webber SA, Naftel DC, Fricker FJ, Olesnevich P, Blume ED, Addonizio L, Kirklin JK, Canter CE. Lymphoproliferative disorders after paediatric heart transplantation: a multi-institutional study. Lancet. 2006 Jan 21; 367(9506):233-9.
  63. Rosenthal D, Chrisant MR, Edens E, Mahony L, Canter C, Colan S, Dubin A, Lamour J, Ross R, Shaddy R, Addonizio L, Beerman L, Berger S, Bernstein D, Blume E, Boucek M, Checchia P, Dipchand A, Drummond-Webb J, Fricker J, Friedman R, Hallowell S, Jaquiss R, Mital S, Pahl E, Pearce FB, Pearce B, Rhodes L, Rotondo K, Rusconi P, Scheel J, Pal Singh T, Towbin J. International Society for Heart and Lung Transplantation: Practice guidelines for management of heart failure in children. J Heart Lung Transplant. 2004 Dec; 23(12):1313-33.
  64. DeMaso DR, Douglas Kelley S, Bastardi H, O'Brien P, Blume ED. The longitudinal impact of psychological functioning, medical severity, and family functioning in pediatric heart transplantation. J Heart Lung Transplant. 2004 Apr; 23(4):473-80.
  65. Chin C, Naftel DC, Singh TP, Blume ED, Luikart H, Bernstein D, Gamberg P, Kirklin JK, Morrow WR. Risk factors for recurrent rejection in pediatric heart transplantation: a multicenter experience. J Heart Lung Transplant. 2004 Feb; 23(2):178-85.
  66. Blume ED. Current status of heart transplantation in children: update 2003. Pediatr Clin North Am. 2003 Dec; 50(6):1375-91.
  67. Collins KK, Thiagarajan RR, Chin C, Dubin AM, Van Hare GF, Robbins RC, Mayer JE, Bernstein D, Berul CI, Blume ED. Atrial tachyarrhythmias and permanent pacing after pediatric heart transplantation. J Heart Lung Transplant. 2003 Oct; 22(10):1126-33.
  68. Thiagarajan RR, Roth SJ, Margossian S, Mackie AS, Neufeld EJ, Laussen PC, Forbess JM, Blume ED. Extracorporeal membrane oxygenation as a bridge to cardiac transplantation in a patient with cardiomyopathy and hemophilia A. Intensive Care Med. 2003 Jun; 29(6):985-8.
  69. Rakhit A, Nurko S, Gauvreau K, Mayer JE, Blume ED. Gastrointestinal complications after pediatric cardiac transplantation. J Heart Lung Transplant. 2002 Jul; 21(7):751-9.
  70. Scheule AM, Zurakowski D, Blume ED, Stamm C, del Nido PJ, Mayer JE, Jonas RA. Arterial switch operation with a single coronary artery. J Thorac Cardiovasc Surg. 2002 Jun; 123(6):1164-72.
  71. Laufs H, Nigrovic PA, Schneider LC, Oettgen H, Del NP, Moskowitz IP, Blume E, Perez-Atayde AR. Giant cell myocarditis in a 12-year-old girl with common variable immunodeficiency. Mayo Clin Proc. 2002 Jan; 77(1):92-6.
  72. Powell AJ, Gauvreau K, Jenkins KJ, Blume ED, Mayer JE, Lock JE. Perioperative risk factors for development of protein-losing enteropathy following a Fontan procedure. Am J Cardiol. 2001 Nov 15; 88(10):1206-9.
  73. Goff DA, Blume ED, Gauvreau K, Mayer JE, Lock JE, Jenkins KJ. Clinical outcome of fenestrated Fontan patients after closure: the first 10 years. Circulation. 2000 Oct 24; 102(17):2094-9.
  74. Schermerhorn ML, Nelson DP, Blume ED, Phillips L, Mayer JE. Sialyl LewisX oligosaccharide preserves myocardial and endothelial function during cardioplegic ischemia. Ann Thorac Surg. 2000 Sep; 70(3):890-4.
  75. Ibrahim AE, Duncan BW, Blume ED, Jonas RA. Long-term follow-up of pediatric cardiac patients requiring mechanical circulatory support. Ann Thorac Surg. 2000 Jan; 69(1):186-92.
  76. Geggel RL, Perry SB, Blume ED, Baker CM. Left superior vena cava connection to unroofed coronary sinus associated with positional cyanosis: successful transcatheter treatment using Gianturco-Grifka vascular occlusion device. Catheter Cardiovasc Interv. 1999 Dec; 48(4):369-73.
  77. Wattanasirichaigoon D, Vesely MR, Duggal P, Levine JC, Blume ED, Wolff GS, Edwards SB, Beggs AH. Sodium channel abnormalities are infrequent in patients with long QT syndrome: identification of two novel SCN5A mutations. Am J Med Genet. 1999 Oct 29; 86(5):470-6.
  78. Blume ED, Altmann K, Mayer JE, Colan SD, Gauvreau K, Geva T. Evolution of risk factors influencing early mortality of the arterial switch operation. J Am Coll Cardiol. 1999 May; 33(6):1702-9.
  79. Blume ED, Chung T, Hoffer FA, Geva T. Images in cardiovascular medicine. Anatomically corrected malposition of the great arteries [S,D,L]. Circulation. 1998 Mar 31; 97(12):1207.
  80. Blume ED, Wernovsky G. Long-term results of arterial switch repair of transposition of the great vessels. Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu. 1998; 1:129-138.
  81. Blume ED, Nelson DP, Gauvreau K, Walsh AZ, Plumb C, Neufeld EJ, Hickey PR, Mayer JE, Newburger JW. Soluble adhesion molecules in infants and children undergoing cardiopulmonary bypass. Circulation. 1997 Nov 4; 96(9 Suppl):II-352-7.
  82. Blume E. A switch in time saves a statistical bind. JAMA. 1991 Dec 18; 266(23):3284-5.
  83. Blume E. Amnesic patients give clues on structure of memory. JAMA. 1983 Oct 7; 250(13):1662-3.
  84. Blume E. Palliation may block cure of incontinence in elderly. JAMA. 1983 Sep 16; 250(11):1371.
  85. Blume E. Elderly patient needs assessment, not neglect. JAMA. 1983 Sep 2; 250(9):1132-3.
  86. Blume E. Street drugs yield primate Parkinson's model. JAMA. 1983 Jul 1; 250(1):13-4.
  87. Blume E. Premenstrual syndromes, depression linked. JAMA. 1983 Jun 3; 249(21):2864-6.
  88. Blume E. Ambulatory dialysis: special boon for children. JAMA. 1983 May 6; 249(17):2290-1.
  89. Blume E. 'Tricks' of trade aid kidney transplants. JAMA. 1983 May 6; 249(17):2288-90.
  90. Blume E. Promising agents for limiting renal damage. JAMA. 1983 Apr 15; 249(15):1987.
  91. Colgan SP, Taylor CT, Narravula S, Synnestvedt K, Blume ED. Endothelial COX-2 induction by hypoxia liberates 6-keto-PGF1 alpha, a potent epithelial secretagogue. Adv Exp Med Biol. 2002; 507:107-12.
  92. Blume ED, Taylor CT, Lennon PF, Stahl GL, Colgan SP. Activated endothelial cells elicit paracrine induction of epithelial chloride secretion. 6-Keto-PGF1alpha is an epithelial secretagogue. J Clin Invest. 1998 Sep 15; 102(6):1161-72.
  93. Daly KP, Marshall AC, Vincent JA, Zuckerman WA, Hoffman TM, Canter CE, Blume ED, Bergersen L. Endomyocardial biopsy and selective coronary angiography are low-risk procedures in pediatric heart transplant recipients: results of a multicenter experience. J Heart Lung Transplant. 2012 Apr; 31(4):398-409.
  94. Singh TP, Faber C, Blume ED, Worley S, Almond CS, Smoot LB, Dillis S, Nasman C, Boyle GJ. Safety and early outcomes using a corticosteroid-avoidance immunosuppression protocol in pediatric heart transplant recipients. J Heart Lung Transplant. 2010 May; 29(5):517-22.
  95. Blume E. Sound, shock waves shatter kidney stones. JAMA. 1983 May 13; 249(18):2434-5.
  96. Almond CS, Harrington J, Thiagarajan R, Duncan CN, LaPierre R, Halwick D, Blume ED, Del Nido PJ, Neufeld EJ, McGowan FX. Successful use of bivalirudin for cardiac transplantation in a child with heparin-induced thrombocytopenia. J Heart Lung Transplant. 2006 Nov; 25(11):1376-9.
  97. Bruns LA, Chrisant MK, Lamour JM, Shaddy RE, Pahl E, Blume ED, Hallowell S, Addonizio LJ, Canter CE. Carvedilol as therapy in pediatric heart failure: an initial multicenter experience. J Pediatr. 2001 Apr; 138(4):505-11.
  98. Larsen RL, Canter CE, Naftel DC, Tressler M, Rosenthal DN, Blume ED, Mahle WT, Yung D, Morrow WR, Orav EJ, Wilkinson JD, Towbin JA, Lipshultz SE. The impact of heart failure severity at time of listing for cardiac transplantation on survival in pediatric cardiomyopathy. J Heart Lung Transplant. 2011 Jul; 30(7):755-60.
  99. Lunze FI, Colan SD, Gauvreau K, Chen MH, Perez-Atayde AR, Blume ED, Singh TP. Cardiac allograft function during the first year after transplantation in rejection-free children and young adults. Circ Cardiovasc Imaging. 2012 Nov; 5(6):756-64.
  100. Morell E, Wolfe J, Scheurer M, Thiagarajan R, Morin C, Beke DM, Smoot L, Cheng H, Gauvreau K, Blume ED. Patterns of care at end of life in children with advanced heart disease. Arch Pediatr Adolesc Med. 2012 Aug; 166(8):745-8.
  101. Chen MH, Abernathey E, Lunze F, Colan SD, O'Neill S, Bergersen L, Geva T, Blume ED. Utility of exercise stress echocardiography in pediatric cardiac transplant recipients: a single-center experience. J Heart Lung Transplant. 2012 May; 31(5):517-23.
  102. Lunze FI, Colan SD, Gauvreau K, Perez-Atayde AR, Smith RN, Blume ED, Singh TP. Tissue Doppler imaging for rejection surveillance in pediatric heart transplant recipients. J Heart Lung Transplant. 2013 Oct; 32(10):1027-33.
  103. Kirklin JK, Naftel DC, Pagani FD, Kormos RL, Stevenson LW, Blume ED, Myers SL, Miller MA, Baldwin JT, Young JB. Seventh INTERMACS annual report: 15,000 patients and counting. J Heart Lung Transplant. 2015 Dec; 34(12):1495-504.
  104. Rosenthal DN, Almond CS, Jaquiss RD, Peyton CE, Auerbach SR, Morales DR, Epstein DJ, Cantor RS, Kormos RL, Naftel DC, Butts RJ, Ghanayem NS, Kirklin JK, Blume ED. Adverse events in children implanted with ventricular assist devices in the United States: Data from the Pediatric Interagency Registry for Mechanical Circulatory Support (PediMACS). J Heart Lung Transplant. 2016 May; 35(5):569-77.
  105. Daly KP, Stack M, Eisenga MF, Keane JF, Zurakowski D, Blume ED, Briscoe DM. Vascular endothelial growth factor A is associated with the subsequent development of moderate or severe cardiac allograft vasculopathy in pediatric heart transplant recipients. J Heart Lung Transplant. 2016 Oct 3.
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