Ari J.  Fried

Ari J. Fried, MD

Attending Physician

Instructor of Pediatrics, Harvard Medical School

    Contact: 617-355-6117
  • Fax: 617-730-0310

Medical Services


  • Mast Cell Disorders
  • Immunotherapy
  • Food Allergy
  • Asthma
  • Allergy Immunology
  • Immunodeficiency
  • Eosinophilic Diseases of Gastrointestinal Tract
  • Eosinophilic Esophagitis
  • Allergic Rhinitis
  • Allergic Gastrointestinal Disorders
  • Anaphylaxis
  • Recurrent Infections


  • Allergy Immunology


  • English
  • German
  • Spanish


  • Allergy Program
  • Immunology Program
  • Primary Immunodeficiency Disorders Program
To schedule an appointment: Call 617-355-6117 or Request an Appointment

Experience and Education


Medical School

Christian-Albrechts-Universitaet Kiel,

Kiel, Germany

Internship, Pediatrics

University of Iowa Hospital,

Iowa City, IA

Residency, Pediatrics

University of Iowa Hospital,

Iowa City, IA

Fellowship, Allergy/Immunology

Boston Children's Hospital,

Boston, MA


  • American Board of Allergy and Immunology


Publications powered by Harvard Catalyst Profiles
  1. Chinen J, Badran YR, Geha RS, Chou JS, Fried AJ. Advances in basic and clinical immunology in 2016. J Allergy Clin Immunol. 2017 Oct; 140(4):959-973.
  2. Platt CD, Fried AJ, Hoyos-Bachiloglu R, Usmani GN, Schmidt B, Whangbo J, Chiarle R, Chou J, Geha RS. Combined immunodeficiency with EBV positive B cell lymphoma and epidermodysplasia verruciformis due to a novel homozygous mutation in RASGRP1. Clin Immunol. 2017 10; 183:142-144.
  3. Johnston AM, Niemela J, Rosenzweig SD, Fried AJ, Delmonte OM, Fleisher TA, Kuehn H. A Novel Mutation in IKBKG/NEMO Leads to Ectodermal Dysplasia with Severe Immunodeficiency (EDA-ID). J Clin Immunol. 2016 Aug; 36(6):541-3.
  4. Rubinstein E, Lee JJ, Fried A, Logvinenko T, Ngo P, McDonald D, Hait EJ. Comparison of 2 delivery vehicles for viscous budesonide to treat eosinophilic esophagitis in children. J Pediatr Gastroenterol Nutr. 2014 Sep; 59(3):317-20.
  5. Fried AJ, Akin C. Primary mast cell disorders in children. Curr Allergy Asthma Rep. 2013 Dec; 13(6):693-701.
  6. Fried AJ, Altrich ML, Liu H, Halsey JF, Bonilla FA. Correlation of pneumococcal antibody concentration and avidity with patient clinical and immunologic characteristics. J Clin Immunol. 2013 May; 33(4):847-56.
  7. Recher M, Fried AJ, Massaad MJ, Kim HY, Rizzini M, Frugoni F, Walter JE, Mathew D, Eibel H, Hess C, Giliani S, Umetsu DT, Notarangelo LD, Geha RS. Intronic SH2D1A mutation with impaired SAP expression and agammaglobulinemia. Clin Immunol. 2013 Feb; 146(2):84-9.
  8. Lee JJ, Fried AJ, Hait E, Yen EH, Perkins JM, Rubinstein E. Topical inhaled ciclesonide for treatment of eosinophilic esophagitis. J Allergy Clin Immunol. 2012 Oct; 130(4):1011; author reply 1011-2.
  9. Goldman FD, Gurel Z, Al-Zubeidi D, Fried AJ, Icardi M, Song C, Dovat S. Congenital pancytopenia and absence of B lymphocytes in a neonate with a mutation in the Ikaros gene. Pediatr Blood Cancer. 2012 Apr; 58(4):591-7.
  10. Fried AJ, Rauter I, Dillon SR, Jabara HH, Geha RS. Functional analysis of transmembrane activator and calcium-modulating cyclophilin ligand interactor (TACI) mutations associated with common variable immunodeficiency. J Allergy Clin Immunol. 2011 Jul; 128(1):226-228.e1.
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  12. Fried AJ, Oettgen HC. Anti-IgE in the treatment of allergic disorders in pediatrics. Curr Opin Pediatr. 2010 Dec; 22(6):758-64.
  13. Fried AJ, Bonilla FA. Pathogenesis, diagnosis, and management of primary antibody deficiencies and infections. Clin Microbiol Rev. 2009 Jul; 22(3):396-414.
  14. Borzutzky A, Fried A, Chou J, Bonilla FA, Kim S, Dedeoglu F. NOD2-associated diseases: Bridging innate immunity and autoinflammation. Clin Immunol. 2010 Mar; 134(3):251-61.
  15. Fried A, Berg M, Sharma B, Bonde S, Zavazava N. Recombinant dimeric MHC antigens protect cardiac allografts from rejection and visualize alloreactive T cells. J Leukoc Biol. 2005 Sep; 78(3):595-604.
  16. Behrens D, Lange K, Fried A, Yoo-Ott KA, Richter K, Fändrich F, Krönke M, Zavazava N. Donor-derived soluble MHC antigens plus low-dose cyclosporine induce transplantation unresponsiveness independent of the thymus by down-regulating T cell-mediated alloresponses in a rat transplantation model. Transplantation. 2001 Dec 27; 72(12):1974-82.
To schedule an appointment: Call 617-355-6117 or Request an Appointment


Boston Children’s is so much more than a hospital—it’s a community of researchers, clinicians, administrators, support staff, innovators, teachers, patients and families, all working together to make the impossible possible. ”
- Sandra L. Fenwick, President and CEO

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