Current Environment: Production

Medical Services

Programs & Services

Languages

  • English

Education

Graduate School

Medical Informatics

University of Utah

Salt Lake City, UT

Graduate School

Psychology

California State University

Fresno, CA

Medical School

Stanford University School of Medicine

Stanford, CA

Internship

Children's Hospital of Philadelphia

Philadelphia, PA

Residency

University of California Medical Center

San Francisco, CA

Fellowship

Pediatric Critical Care Medicine

University of California at San Francisco and Children's Hospital

Oakland, CA

Fellowship

Health Outcomes and Health Policy Research

University of California at San Francisco

San Francisco, CA

Fellowship

Cardiovascular Medicine

University of California at San Francisco

San Francisco, CA

Fellowship

University of Utah

Salt Lake City, UT

Fellowship

University of Toronto

Toronto, Ontario

Certifications

  • American Board of Pediatrics (Critical Care Medicine)
  • American Board of Pediatrics (General)

Professional History

Dr. Randolph serves as an expert for the Department of Medicine for Boston Children's Hospital Precision Medicine Service. For more information about the Precision Medicine Service please visit bostonchildrens.org/precisionmed.

Publications

  1. Use of procalcitonin in therapeutic decisions in the pediatric intensive care unit. Ann Intensive Care. 2025 Apr 23; 15(1):55. View Abstract

  2. Concordance between parent-reported and documented COVID-19 vaccination status among hospitalized children and adolescents: Implications for vaccine effectiveness estimates, May 2021-October 2023. Vaccine. 2025 Apr 30; 54:126891. View Abstract

  3. The 2024 Phoenix Sepsis Score Criteria: Part 1, the Evolution in Definition of Sepsis and Septic Shock. Pediatr Crit Care Med. 2025 Feb 01; 26(2):e246-e251. View Abstract

  4. The 2024 Phoenix Sepsis Score Criteria: Part 3, What About Using Stages of Sepsis in the Criteria? Pediatr Crit Care Med. 2025 Feb 01; 26(2):e256-e261. View Abstract

  5. The 2024 Phoenix Sepsis Score Criteria: Part 5, What About "Parsimony" in the Criteria-Is Less Really More? Pediatr Crit Care Med. 2025 Feb 01; 26(2):e266-e271. View Abstract

  6. Assessing Clinical Improvement of Infants Hospitalized for Respiratory Syncytial Virus-Related Critical Illness. J Infect Dis. 2025 Jan 15. View Abstract

  7. Hospital-wide access to genomic data advanced pediatric rare disease research and clinical outcomes. NPJ Genom Med. 2024 Dec 02; 9(1):60. View Abstract

  8. Impact of Viral Lower Respiratory Tract Infection (LRTI) in Early Childhood (0-2 Years) on Lung Growth and Development and Lifelong Trajectories of Pulmonary Health: A National Institutes of Health (NIH) Workshop Summary. Pediatr Pulmonol. 2025 Jan; 60(1):e27357. View Abstract

  9. Consequences beyond acute SARS-CoV-2 infection in children. Sci Transl Med. 2024 Nov 13; 16(773):eado2099. View Abstract

  10. Causal inference can lead us to modifiable mechanisms and informative archetypes in sepsis. Intensive Care Med. 2024 Dec; 50(12):2031-2042. View Abstract

  11. Pre-existing Immunocompromising Conditions and Outcomes of Acute COVID-19 Patients Admitted for Pediatric Intensive Care. Clin Infect Dis. 2024 08 16; 79(2):395-404. View Abstract

  12. High expression of oleoyl-ACP hydrolase underpins life-threatening respiratory viral diseases. Cell. 2024 Aug 22; 187(17):4586-4604.e20. View Abstract

  13. Molecular mimicry in multisystem inflammatory syndrome in children. Nature. 2024 Aug; 632(8025):622-629. View Abstract

  14. From ICU Syndromes to ICU Subphenotypes: Consensus Report and Recommendations for Developing Precision Medicine in the ICU. Am J Respir Crit Care Med. 2024 07 15; 210(2):155-166. View Abstract

  15. Enhancing sepsis biomarker development: key considerations from public and private perspectives. Crit Care. 2024 07 13; 28(1):238. View Abstract

  16. Durability of Original Monovalent mRNA Vaccine Effectiveness Against COVID-19 Omicron-Associated Hospitalization in Children and Adolescents - United States, 2021-2023. MMWR Morb Mortal Wkly Rep. 2024 Apr 18; 73(15):330-338. View Abstract

  17. Adolescents and Young Adults: An Understudied, yet Likely Informative, Population in ARDS. Am J Respir Crit Care Med. 2024 04 01; 209(7):785-786. View Abstract

  18. International Consensus Criteria for Pediatric Sepsis and Septic Shock. JAMA. 2024 02 27; 331(8):665-674. View Abstract

  19. Development and Validation of the Phoenix Criteria for Pediatric Sepsis and Septic Shock. JAMA. 2024 02 27; 331(8):675-686. View Abstract

  20. The RECOVERY trial of PIMS-TS: important lessons from the pandemic. Lancet Child Adolesc Health. 2024 03; 8(3):176-177. View Abstract

  21. Characteristics and Clinical Outcomes of Vaccine-Eligible US Children Under-5 Years Hospitalized for Acute COVID-19 in a National Network. Pediatr Infect Dis J. 2024 Mar 01; 43(3):242-249. View Abstract

  22. Neutralization of SARS-CoV-2 Omicron BQ.1, BQ.1.1 and XBB.1 variants following SARS-CoV-2 infection or vaccination in children. Nat Commun. 2023 12 01; 14(1):7952. View Abstract

  23. Type I interferon signature and cycling lymphocytes in macrophage activation syndrome. J Clin Invest. 2023 11 15; 133(22). View Abstract

  24. Risk factors for health impairments in children after hospitalization for acute COVID-19 or MIS-C. Front Pediatr. 2023; 11:1260372. View Abstract

  25. Effectiveness of Maternal mRNA COVID-19 Vaccination During Pregnancy Against COVID-19-Associated Hospitalizations in Infants Aged <6 Months During SARS-CoV-2 Omicron Predominance - 20 States, March 9, 2022-May 31, 2023. MMWR Morb Mortal Wkly Rep. 2023 Sep 29; 72(39):1057-1064. View Abstract

  26. The Modified Clinical Progression Scale for Pediatric Patients: Evaluation as a Severity Metric and Outcome Measure in Severe Acute Viral Respiratory Illness. Pediatr Crit Care Med. 2023 Dec 01; 24(12):998-1009. View Abstract

  27. Infants Admitted to US Intensive Care Units for RSV Infection During the 2022 Seasonal Peak. JAMA Netw Open. 2023 08 01; 6(8):e2328950. View Abstract

  28. Transcriptomic profiles of multiple organ dysfunction syndrome phenotypes in pediatric critical influenza. Front Immunol. 2023; 14:1220028. View Abstract

  29. Early, Persistent Lymphopenia Is Associated With Prolonged Multiple Organ Failure and Mortality in Septic Children. Crit Care Med. 2023 12 01; 51(12):1766-1776. View Abstract

  30. Neurological and Psychological Sequelae Associated With Multisystem Inflammatory Syndrome in Children. JAMA Netw Open. 2023 07 03; 6(7):e2324369. View Abstract

  31. Immunomodulatory Therapy for MIS-C. Pediatrics. 2023 Jul 01; 152(1). View Abstract

  32. Single cell transcriptomics identifies distinct profiles in pediatric acute respiratory distress syndrome. Nat Commun. 2023 06 30; 14(1):3870. View Abstract

  33. Longitudinal Analysis of Contrasts in Gene Expression Data. Genes (Basel). 2023 05 24; 14(6). View Abstract

  34. Variation in Early Anakinra Use and Short-Term Outcomes in Multisystem Inflammatory Syndrome in Children. Arthritis Rheumatol. 2023 08; 75(8):1466-1476. View Abstract

  35. Operationalizing Appropriate Sepsis Definitions in Children Worldwide: Considerations for the Pediatric Sepsis Definition Taskforce. Pediatr Crit Care Med. 2023 06 01; 24(6):e263-e271. View Abstract

  36. Extracorporeal Membrane Oxygenation Characteristics and Outcomes in Children and Adolescents With COVID-19 or Multisystem Inflammatory Syndrome Admitted to U.S. ICUs. Pediatr Crit Care Med. 2023 05 01; 24(5):356-371. View Abstract

  37. Risk Factors for Multisystem Inflammatory Syndrome in Children: A Case-control Investigation. Pediatr Infect Dis J. 2023 06 01; 42(6):e190-e196. View Abstract

  38. Community-Onset Bacterial Coinfection in Children Critically Ill With Severe Acute Respiratory Syndrome Coronavirus 2 Infection. Open Forum Infect Dis. 2023 Mar; 10(3):ofad122. View Abstract

  39. Clinical Course Associated with Aseptic Meningitis Induced by Intravenous Immunoglobulin for the Treatment of Multisystem Inflammatory Syndrome in Children. J Pediatr. 2023 06; 257:113372. View Abstract

  40. Factors Associated With COVID-19 Non-vaccination in Adolescents Hospitalized Without COVID-19. J Pediatric Infect Dis Soc. 2023 Feb 09; 12(1):29-35. View Abstract

  41. BNT162b2 mRNA Vaccination Against Coronavirus Disease 2019 is Associated With a Decreased Likelihood of Multisystem Inflammatory Syndrome in Children Aged 5-18 Years-United States, July 2021 - April 2022. Clin Infect Dis. 2023 02 08; 76(3):e90-e100. View Abstract

  42. Life-Threatening Complications of Influenza vs Coronavirus Disease 2019 (COVID-19) in US Children. Clin Infect Dis. 2023 02 08; 76(3):e280-e290. View Abstract

  43. Executive Summary of the Second International Guidelines for the Diagnosis and Management of Pediatric Acute Respiratory Distress Syndrome (PALICC-2). Pediatr Crit Care Med. 2023 02 01; 24(2):143-168. View Abstract

  44. Pulmonary Specific Ancillary Treatment for Pediatric Acute Respiratory Distress Syndrome: From the Second Pediatric Acute Lung Injury Consensus Conference. Pediatr Crit Care Med. 2023 02 01; 24(12 Suppl 2):S99-S111. View Abstract

  45. Genetic Predisposition to Neurological Complications in Patients with COVID-19. Biomolecules. 2023 01 09; 13(1). View Abstract

  46. ATP breakdown in plasma of children limits the antimicrobial effectiveness of their neutrophils. Purinergic Signal. 2023 12; 19(4):651-662. View Abstract

  47. Circulating Spike Protein Detected in Post-COVID-19 mRNA Vaccine Myocarditis. Circulation. 2023 03 14; 147(11):867-876. View Abstract

  48. The Notch1/CD22 signaling axis disrupts Treg function in SARS-CoV-2-associated multisystem inflammatory syndrome in children. J Clin Invest. 2023 01 03; 133(1). View Abstract

  49. Changes in Distribution of Severe Neurologic Involvement in US Pediatric Inpatients With COVID-19 or Multisystem Inflammatory Syndrome in Children in 2021 vs 2020. JAMA Neurol. 2023 01 01; 80(1):91-98. View Abstract

  50. Unsupervised outlier detection applied to SARS-CoV-2 nucleotide sequences can identify sequences of common variants and other variants of interest. BMC Bioinformatics. 2022 Dec 19; 23(1):547. View Abstract

  51. Computer clinical decision support that automates personalized clinical care: a challenging but needed healthcare delivery strategy. J Am Med Inform Assoc. 2022 12 13; 30(1):178-194. View Abstract

  52. NFKB2 haploinsufficiency identified via screening for IFN-a2 autoantibodies in children and adolescents hospitalized with SARS-CoV-2-related complications. J Allergy Clin Immunol. 2023 04; 151(4):926-930.e2. View Abstract

  53. DDX58 Is Associated With Susceptibility to Severe Influenza Virus Infection in Children and Adolescents. J Infect Dis. 2022 11 28; 226(11):2030-2036. View Abstract

  54. Association of Asthma With Treatments and Outcomes in Children With Critical Influenza. J Allergy Clin Immunol Pract. 2023 03; 11(3):836-843.e3. View Abstract

  55. Pediatric Acute Lung Injury and Sepsis Investigators (PALISI): Evolution of an Investigator-Initiated Research Network. Pediatr Crit Care Med. 2022 12 01; 23(12):1056-1066. View Abstract

  56. Postdischarge Glucocorticoid Use and Clinical Outcomes of Multisystem Inflammatory Syndrome in Children. JAMA Netw Open. 2022 11 01; 5(11):e2241622. View Abstract

  57. Tachyarrhythmias During Hospitalization for COVID-19 or Multisystem Inflammatory Syndrome in Children and Adolescents. J Am Heart Assoc. 2022 10 18; 11(20):e025915. View Abstract

  58. Measurement of Severe Acute Respiratory Syndrome Coronavirus 2 Antigens in Plasma of Pediatric Patients With Acute Coronavirus Disease 2019 or Multisystem Inflammatory Syndrome in Children Using an Ultrasensitive and Quantitative Immunoassay. Clin Infect Dis. 2022 10 12; 75(8):1351-1358. View Abstract

  59. Host Respiratory Transcriptome Signature Associated with Poor Outcome in Children with Influenza-Staphylococcus aureus Pneumonia. J Infect Dis. 2022 09 28; 226(7):1286-1294. View Abstract

  60. COVID-19 and children. Science. 2022 09 09; 377(6611):1144-1149. View Abstract

  61. Investigating Health Disparities Associated With Multisystem Inflammatory Syndrome in Children After SARS-CoV-2 Infection. Pediatr Infect Dis J. 2022 11 01; 41(11):891-898. View Abstract

  62. Health Impairments in Children and Adolescents After Hospitalization for Acute COVID-19 or MIS-C. Pediatrics. 2022 09 01; 150(3). View Abstract

  63. SARS-CoV-2-specific T cell responses in patients with multisystem inflammatory syndrome in children. Clin Immunol. 2022 Oct; 243:109106. View Abstract

  64. Vaccine Effectiveness Against Life-Threatening Influenza Illness in US Children. Clin Infect Dis. 2022 08 25; 75(2):230-238. View Abstract

  65. Author Correction: Cross-reactive immunity against the SARS-CoV-2 Omicron variant is low in pediatric patients with prior COVID-19 or MIS-C. Nat Commun. 2022 Aug 12; 13(1):4732. View Abstract

  66. Treatment of Multisystem Inflammatory Syndrome in Children: Understanding Differences in Results of Comparative Effectiveness Studies. ACR Open Rheumatol. 2022 Sep; 4(9):804-810. View Abstract

  67. Maternal Vaccination and Risk of Hospitalization for Covid-19 among Infants. N Engl J Med. 2022 07 14; 387(2):109-119. View Abstract

  68. A Description of COVID-19-Directed Therapy in Children Admitted to US Intensive Care Units 2020. J Pediatric Infect Dis Soc. 2022 May 30; 11(5):191-198. View Abstract

  69. Cross-reactive immunity against the SARS-CoV-2 Omicron variant is low in pediatric patients with prior COVID-19 or MIS-C. Nat Commun. 2022 05 27; 13(1):2979. View Abstract

  70. Notch1-CD22-Dependent Immune Dysregulation in the SARS-CoV2-Associated Multisystem Inflammatory Syndrome in Children. Res Sq. 2022 Apr 11. View Abstract

  71. BNT162b2 Protection against the Omicron Variant in Children and Adolescents. N Engl J Med. 2022 05 19; 386(20):1899-1909. View Abstract

  72. Resuscitation Fluid Composition and Acute Kidney Injury in Critical Illness. N Engl J Med. 2022 03 03; 386(9):888-889. View Abstract

  73. Candidacy for Extracorporeal Life Support in Children After Hematopoietic Cell Transplantation: A Position Paper From the Pediatric Acute Lung Injury and Sepsis Investigators Network's Hematopoietic Cell Transplant and Cancer Immunotherapy Subgroup. Pediatr Crit Care Med. 2022 03 01; 23(3):205-213. View Abstract

  74. Frequency, Characteristics and Complications of COVID-19 in Hospitalized Infants. Pediatr Infect Dis J. 2022 03 01; 41(3):e81-e86. View Abstract

  75. Effectiveness of Maternal Vaccination with mRNA COVID-19 Vaccine During Pregnancy Against COVID-19-Associated Hospitalization in Infants Aged <6 Months - 17 States, July 2021-January 2022. MMWR Morb Mortal Wkly Rep. 2022 Feb 18; 71(7):264-270. View Abstract

  76. Systemic and Lower Respiratory Tract Immunity to SARS-CoV-2 Omicron and Variants in Pediatric Severe COVID-19 and Mis-C. Vaccines (Basel). 2022 Feb 10; 10(2). View Abstract

  77. Immunology of SARS-CoV-2 infection in children. Nat Immunol. 2022 02; 23(2):177-185. View Abstract

  78. Effectiveness of BNT162b2 (Pfizer-BioNTech) mRNA Vaccination Against Multisystem Inflammatory Syndrome in Children Among Persons Aged 12-18 Years - United States, July-December 2021. MMWR Morb Mortal Wkly Rep. 2022 Jan 14; 71(2):52-58. View Abstract

  79. Effectiveness of BNT162b2 Vaccine against Critical Covid-19 in Adolescents. N Engl J Med. 2022 02 24; 386(8):713-723. View Abstract

  80. Optical genome mapping identifies rare structural variations as predisposition factors associated with severe COVID-19. iScience. 2022 Feb 18; 25(2):103760. View Abstract

  81. Severe COVID-19 and Multisystem Inflammatory Syndrome in Children in Children and Adolescents. Crit Care Clin. 2022 Jul; 38(3):571-586. View Abstract

  82. An Update on Multisystem Inflammatory Syndrome in Children Related to SARS-CoV-2. Pediatr Infect Dis J. 2022 01 01; 41(1):e6-e9. View Abstract

  83. Multisystem Inflammatory-like Syndrome in a Child Following COVID-19 mRNA Vaccination. Vaccines (Basel). 2021 Dec 30; 10(1). View Abstract

  84. Modeling the Impacts of Clinical Influenza Testing on Influenza Vaccine Effectiveness Estimates. J Infect Dis. 2021 12 15; 224(12):2035-2042. View Abstract

  85. Measurement of SARS-CoV-2 antigens in plasma of pediatric patients with acute COVID-19 or MIS-C using an ultrasensitive and quantitative immunoassay. medRxiv. 2021 Dec 09. View Abstract

  86. Surfactant protein D is a biomarker of influenza-related pediatric lung injury. Pediatr Pulmonol. 2022 02; 57(2):519-528. View Abstract

  87. Effectiveness of Pfizer-BioNTech mRNA Vaccination Against COVID-19 Hospitalization Among Persons Aged 12-18 Years - United States, June-September 2021. MMWR Morb Mortal Wkly Rep. 2021 Oct 22; 70(42):1483-1488. View Abstract

  88. Estimated Pao2: A Continuous and Noninvasive Method to Estimate Pao2 and Oxygenation Index. Crit Care Explor. 2021 Oct; 3(10):e0546. View Abstract

  89. Data-driven clustering identifies features distinguishing multisystem inflammatory syndrome from acute COVID-19 in children and adolescents. EClinicalMedicine. 2021 Oct; 40:101112. View Abstract

  90. Therapy for Multisystem Inflammatory Syndrome in Children. Reply. N Engl J Med. 2021 09 23; 385(13):e42. View Abstract

  91. Rate of thrombosis in children and adolescents hospitalized with COVID-19 or MIS-C. Blood. 2021 07 15; 138(2):190-198. View Abstract

  92. Mechanisms underlying genetic susceptibility to multisystem inflammatory syndrome in children (MIS-C). J Allergy Clin Immunol. 2021 09; 148(3):732-738.e1. View Abstract

  93. Genome-wide association analysis of COVID-19 mortality risk in SARS-CoV-2 genomes identifies mutation in the SARS-CoV-2 spike protein that colocalizes with P.1 of the Brazilian strain. Genet Epidemiol. 2021 10; 45(7):685-693. View Abstract

  94. Multisystem Inflammatory Syndrome in Children - Initial Therapy and Outcomes. N Engl J Med. 2021 07 01; 385(1):23-34. View Abstract

  95. Enabling a learning healthcare system with automated computer protocols that produce replicable and personalized clinician actions. J Am Med Inform Assoc. 2021 06 12; 28(6):1330-1344. View Abstract

  96. Variation in Intravenous Acetaminophen Use in Pediatric Hospitals: Priorities for Standardization. Hosp Pediatr. 2021 07; 11(7):734-742. View Abstract

  97. Incidence of Multisystem Inflammatory Syndrome in Children Among US Persons Infected With SARS-CoV-2. JAMA Netw Open. 2021 06 01; 4(6):e2116420. View Abstract

  98. Incorporating Real-time Influenza Detection Into the Test-negative Design for Estimating Influenza Vaccine Effectiveness: The Real-time Test-negative Design (rtTND). Clin Infect Dis. 2021 05 04; 72(9):1669-1675. View Abstract

  99. Sepsis Subclasses: A Framework for Development and Interpretation. Crit Care Med. 2021 05 01; 49(5):748-759. View Abstract

  100. Neurologic Involvement in Children and Adolescents Hospitalized in the United States for COVID-19 or Multisystem Inflammatory Syndrome. JAMA Neurol. 2021 05 01; 78(5):536-547. View Abstract

  101. Characteristics and Outcomes of US Children and Adolescents With Multisystem Inflammatory Syndrome in Children (MIS-C) Compared With Severe Acute COVID-19. JAMA. 2021 03 16; 325(11):1074-1087. View Abstract

  102. Publisher Correction: Exuberant fibroblast activity compromises lung function via ADAMTS4. Nature. 2020 Dec; 588(7836):E5. View Abstract

  103. Exuberant fibroblast activity compromises lung function via ADAMTS4. Nature. 2020 11; 587(7834):466-471. View Abstract

  104. Multisystem Inflammatory Syndrome in Children in the United States. Reply. N Engl J Med. 2020 10 29; 383(18):1794-1795. View Abstract

  105. Inclusion of Children in Clinical Trials of Treatments for Coronavirus Disease 2019 (COVID-19). JAMA Pediatr. 2020 Sep 01; 174(9):825-826. View Abstract

  106. Pediatric Cardiac Intensive Care Distribution, Service Delivery, and Staffing in the United States in 2018. Pediatr Crit Care Med. 2020 09; 21(9):797-803. View Abstract

  107. Immune dysregulation and multisystem inflammatory syndrome in children (MIS-C) in individuals with haploinsufficiency of SOCS1. J Allergy Clin Immunol. 2020 11; 146(5):1194-1200.e1. View Abstract

  108. Machine Learning Predicts Prolonged Acute Hypoxemic Respiratory Failure in Pediatric Severe Influenza. Crit Care Explor. 2020 Aug; 2(8):e0175. View Abstract

  109. Multisystem Inflammatory Syndrome in U.S. Children and Adolescents. N Engl J Med. 2020 07 23; 383(4):334-346. View Abstract

  110. Early Amplified Respiratory Bioactive Lipid Response Is Associated With Worse Outcomes in Pediatric Influenza-Related Respiratory Failure. Open Forum Infect Dis. 2020 May; 7(5):ofaa122. View Abstract

  111. RIG-I and TLR4 responses and adverse outcomes in pediatric influenza-related critical illness. J Allergy Clin Immunol. 2020 06; 145(6):1673-1680.e11. View Abstract

  112. Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children. Pediatr Crit Care Med. 2020 02; 21(2):e52-e106. View Abstract

  113. Executive Summary: Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children. Pediatr Crit Care Med. 2020 02; 21(2):186-195. View Abstract

  114. Surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children. Intensive Care Med. 2020 02; 46(Suppl 1):10-67. View Abstract

  115. Executive summary: surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children. Intensive Care Med. 2020 02; 46(Suppl 1):1-9. View Abstract

  116. Growth and Changing Characteristics of Pediatric Intensive Care 2001-2016. Crit Care Med. 2019 08; 47(8):1135-1142. View Abstract

  117. The authors reply. Pediatr Crit Care Med. 2019 08; 20(8):795-796. View Abstract

  118. A Modular Cytokine Analysis Method Reveals Novel Associations With Clinical Phenotypes and Identifies Sets of Co-signaling Cytokines Across Influenza Natural Infection Cohorts and Healthy Controls. Front Immunol. 2019; 10:1338. View Abstract

  119. Evaluation of Mannose Binding Lectin Gene Variants in Pediatric Influenza Virus-Related Critical Illness. Front Immunol. 2019; 10:1005. View Abstract

  120. Cost Implications of Escalating Intravenous Acetaminophen Use in Children. JAMA Pediatr. 2019 05 01; 173(5):489-491. View Abstract

  121. Acute respiratory distress syndrome. Nat Rev Dis Primers. 2019 03 14; 5(1):18. View Abstract

  122. Antibiotic Prescription in Young Children With Respiratory Syncytial Virus-Associated Respiratory Failure and Associated Outcomes. Pediatr Crit Care Med. 2019 02; 20(2):101-109. View Abstract

  123. Vancomycin Monotherapy May Be Insufficient to Treat Methicillin-resistant Staphylococcus aureus Coinfection in Children With Influenza-related Critical Illness. Clin Infect Dis. 2019 01 18; 68(3):365-372. View Abstract

  124. Cytokine Profiles of Severe Influenza Virus-Related Complications in Children. Front Immunol. 2017; 8:1423. View Abstract

  125. A Biosignature Predicting Complicated Course in Children Presenting with Septic Shock. Why PERSEVERE? Am J Respir Crit Care Med. 2017 08 15; 196(4):411-413. View Abstract

  126. SNP-mediated disruption of CTCF binding at the IFITM3 promoter is associated with risk of severe influenza in humans. Nat Med. 2017 Aug; 23(8):975-983. View Abstract

  127. Simulation of a Novel Schedule for Intensivist Staffing to Improve Continuity of Patient Care and Reduce Physician Burnout. Crit Care Med. 2017 Jul; 45(7):1138-1144. View Abstract

  128. Evaluation of IFITM3 rs12252 Association With Severe Pediatric Influenza Infection. J Infect Dis. 2017 07 01; 216(1):14-21. View Abstract

  129. Why So Few Randomized Trials in Pediatric Critical Care Medicine? Ask the Trialists. Pediatr Crit Care Med. 2017 05; 18(5):486-487. View Abstract

  130. Mannose-Binding Lectin Levels in Critically Ill Children With Severe Infections. Pediatr Crit Care Med. 2017 02; 18(2):103-111. View Abstract

  131. 1444: MANNOSE-BINDING LECTIN AND PEDIATRIC SEPSIS SUSCEPTIBILITY: A SYSTEMATIC REVIEW AND META-ANALYSIS. Crit Care Med. 2016 Dec; 44(12 Suppl 1):436. View Abstract

  132. 933: ASSOCIATIONS BETWEEN PNEUMONIA AND CLINICAL OUTCOMES IN PICU PATIENTS WITH RSV BRONCHIOLITIS. Crit Care Med. 2016 Dec; 44(12 Suppl 1):309. View Abstract

  133. Enterovirus D68 Reemerges Globally as a Severe Pathogen Targeting Children. Pediatr Crit Care Med. 2016 11; 17(11):1088-1089. View Abstract

  134. Determinants of red blood cell transfusion in pediatric trauma patients admitted to the intensive care unit. Transfusion. 2017 01; 57(1):187-194. View Abstract

  135. Staphylococcus aureus a-Toxin Response Distinguishes Respiratory Virus-Methicillin-Resistant S. aureus Coinfection in Children. J Infect Dis. 2016 Dec 01; 214(11):1638-1646. View Abstract

  136. The Impact of Clinical Trials Conducted by Research Networks in Pediatric Critical Care. Pediatr Crit Care Med. 2016 09; 17(9):837-44. View Abstract

  137. High Variability in the Reported Management of Hepatic Veno-Occlusive Disease in Children after Hematopoietic Stem Cell Transplantation. Biol Blood Marrow Transplant. 2016 10; 22(10):1823-1828. View Abstract

  138. The authors reply. Pediatr Crit Care Med. 2016 06; 17(6):583-4. View Abstract

  139. Incidence and risk factors for postoperative vomiting following atrial septal defect repair in children. Paediatr Anaesth. 2016 Jun; 26(6):644-8. View Abstract

  140. Optimizing Virus Identification in Critically Ill Children Suspected of Having an Acute Severe Viral Infection. Pediatr Crit Care Med. 2016 Apr; 17(4):279-86. View Abstract

  141. Pragmatic trials in critically ill children are CATCHing on. Lancet. 2016 Apr 23; 387(10029):1697-8. View Abstract

  142. Anesthesiologist- and System-Related Risk Factors for Risk-Adjusted Pediatric Anesthesia-Related Cardiac Arrest. Anesth Analg. 2016 Feb; 122(2):482-9. View Abstract

  143. Severity-of-Illness Scoring in Pediatric Critical Care: Quo Vadis? Pediatr Crit Care Med. 2016 Jan; 17(1):83-5. View Abstract

  144. Pooled Sequencing of Candidate Genes Implicates Rare Variants in the Development of Asthma Following Severe RSV Bronchiolitis in Infancy. PLoS One. 2015; 10(11):e0142649. View Abstract

  145. Critically Ill Children Have Low Vitamin D-Binding Protein, Influencing Bioavailability of Vitamin D. Ann Am Thorac Soc. 2015 Nov; 12(11):1654-61. View Abstract

  146. Therapeutic Hypothermia in Children. N Engl J Med. 2015 09 03; 373(10):979. View Abstract

  147. Pediatric Pulseless Arrest With "Nonshockable" Rhythm: Does Faster Time to Epinephrine Improve Outcome? JAMA. 2015 Aug 25; 314(8):776-7. View Abstract

  148. Recognizing and managing sepsis: what needs to be done? BMC Med. 2015 Apr 27; 13:98. View Abstract

  149. The tremendous burden of sepsis on China's youngest children. Pediatr Crit Care Med. 2014 Nov; 15(9):896-7. View Abstract

  150. Variability in IRBs regarding parental acceptance of passive consent. Pediatrics. 2014 Aug; 134(2):e496-503. View Abstract

  151. More consistent site institutional review board (IRB) input-more consistent site IRB output. Crit Care Med. 2014 May; 42(5):1292-3. View Abstract

  152. A multinational study of thromboprophylaxis practice in critically ill children. Crit Care Med. 2014 May; 42(5):1232-40. View Abstract

  153. Effectiveness of influenza vaccine against life-threatening RT-PCR-confirmed influenza illness in US children, 2010-2012. J Infect Dis. 2014 Sep 01; 210(5):674-83. View Abstract

  154. The authors reply. Pediatr Crit Care Med. 2014 Feb; 15(2):183. View Abstract

  155. Vitamin D-binding protein haplotype is associated with hospitalization for RSV bronchiolitis. Clin Exp Allergy. 2014 Feb; 44(2):231-7. View Abstract

  156. Assessment of hemoglobin threshold for packed RBC transfusion in a medical-surgical PICU. Pediatr Crit Care Med. 2014 Feb; 15(2):e89-94. View Abstract

  157. Rigorous scoping review of randomized trials in pediatric critical care highlights need for a rigorous rethink. Crit Care. 2013 Dec 20; 17(6):1024. View Abstract

  158. Pediatric sepsis: important considerations for diagnosing and managing severe infections in infants, children, and adolescents. Virulence. 2014 Jan 01; 5(1):179-89. View Abstract

  159. The authors reply. Crit Care Med. 2013 Oct; 41(10):e295. View Abstract

  160. Mechanical ventilation strategies in children with acute lung injury: a survey on stated practice pattern*. Pediatr Crit Care Med. 2013 Sep; 14(7):e332-7. View Abstract

  161. The authors reply. Crit Care Med. 2013 May; 41(5):e49. View Abstract

  162. Innate immune function and mortality in critically ill children with influenza: a multicenter study. Crit Care Med. 2013 Jan; 41(1):224-36. View Abstract

  163. A pilot, randomized, controlled clinical trial of lucinactant, a peptide-containing synthetic surfactant, in infants with acute hypoxemic respiratory failure. Pediatr Crit Care Med. 2012 Nov; 13(6):646-53. View Abstract

  164. Risk factors for mechanical ventilation in U.S. children hospitalized with seasonal influenza and 2009 pandemic influenza A*. Pediatr Crit Care Med. 2012 Nov; 13(6):625-31. View Abstract

  165. Fluid balance in critically ill children with acute lung injury. Crit Care Med. 2012 Oct; 40(10):2883-9. View Abstract

  166. Vitamin D deficiency in critically ill children. Pediatrics. 2012 Sep; 130(3):421-8. View Abstract

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  220. Preventing central venous catheter-related complications. In Evidence-Based Resource in Anaesthesia and Analgesia, Editor: Martin R. Tramer. BMJ Books, London UK. 2003; 126-139.

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  230. Mining for the genetic determinants of septic shock: when is it really gold? Crit Care Med. 2002 May; 30(5):1161-3. View Abstract

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  238. Reorganising the delivery of intensive care could improve efficiency and save lives. J Eval Clin Practice. 2002; 8:1-8.

  239. Guidelines for the prevention of intravascular catheter-related infections. Pediatrics. 2002; 110:e51.

  240. Upper gastrointestinal bleeding in the pediatric intensive care unit: clinically important but questionably preventable. Pediatr Crit Care Med. 2001 Oct; 2(4):349-50. View Abstract

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  242. Therapy and validity: Computer Decision Support Systems. In: Guyatt G, Rennie D, editors. Users’ guides to the medical literature. Chicago: AMA Press. 2001; 291-308.

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  245. Prognosis. In: Guyatt G, Rennie D, editors. Users’ guides to the medical literature. Chicago: AMA Press. 2001; 141-54.

  246. Evaluation of a pediatric extubation readiness test. Crit Care Med. 2001; 29:A142.

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  252. Is informed consent always necessary for randomized, controlled trials? . N Engl J Med. 1999 Mar 11; 340(10):804-7. View Abstract

  253. Single versus multilumen central venous catheters: a critical appraisal of the infection risk. Crit Care Med. 1999; 27:A141.

  254. The Pediatric Critical Care Evidence-Based Internet Journal Club: interim evaluation. Crit Care Med. 1999; 27:A99.

  255. Weaning from mechanical ventilation. New Horiz. 1999; 7:374-385.

  256. Antiseptic hub connectors reduce central venous catheter-related sepsis. Crit Care Med. 1999; 27:A141.

  257. Efficacy of continuous vs. intermittent furosemide. Crit Care Med. 1999; 27:A59.

  258. Outcome of out-of-hospital pediatric pulseless arrest. Crit Care Med. 1999; 27:A65.

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  260. Understanding articles describing clinical prediction tools. Evidence Based Medicine in Critical Care Group. Crit Care Med. 1998 Sep; 26(9):1603-12. View Abstract

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  270. Cost-effectiveness of 10 strategies for managing suspected central venous catheter-related infections. Pediatr Res. 1998; 43:155A.

  271. Understanding articles describing clinical prediction tools. Crit Care Med. 1998; 26:1603-12.

  272. Positive predictive value of bilateral absence of somatosensory evoked potentials in severe traumatic brain injury. Pediatr Res. 1998; 43:33A.

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  285. Critical appraisal of “Diagnosis and treatment of ventilator-associated pneumonia—impact on survival” by TR Sterling et al. PedsCCM Evidence-Based Journal Club. 1997; http://PedsCCM.wustl.edu/EBJ/D.

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