EDUCATION

  • University of Witwatersrand , Johannesburg , South Africa

CERTIFICATIONS

PUBLICATIONS

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  1. Sieff CA. Acquired and Inherited Bone Marrow Failure Syndromes. Hematol Oncol Clin North Am. 2018 Aug; 32(4):xiii-xiv. View abstract
  2. Sieff CA. Introduction to Acquired and Inherited Bone Marrow Failure. Hematol Oncol Clin North Am. 2018 Aug; 32(4):569-580. View abstract
  3. Riley LG, Heeney MM, Rudinger-Thirion J, Frugier M, Campagna DR, Zhou R, Hale GA, Hilliard LM, Kaplan JA, Kwiatkowski JL, Sieff CA, Steensma DP, Rennings AJ, Simons A, Schaap N, Roodenburg RJ, Kleefstra T, Arenillas L, Fita-Torró J, Ahmed R, Abboud M, Bechara E, Farah R, Tamminga RY, Bottomley SS, Sanchez M, Swinkels DW, Christodoulou J, Fleming MD. The phenotypic spectrum of germline YARS2 variants: from isolated sideroblastic anemia to mitochondrial myopathy, lactic acidosis and sideroblastic anemia 2. Haematologica. 2018 Jul 19. View abstract
  4. Li H, Lodish HF, Sieff CA. Critical Issues in Diamond-Blackfan Anemia and Prospects for Novel Treatment. Hematol Oncol Clin North Am. 2018 Aug; 32(4):701-712. View abstract
  5. Doulatov S, Vo LT, Macari ER, Wahlster L, Kinney MA, Taylor AM, Barragan J, Gupta M, McGrath K, Lee HY, Humphries JM, DeVine A, Narla A, Alter BP, Beggs AH, Agarwal S, Ebert BL, Gazda HT, Lodish HF, Sieff CA, Schlaeger TM, Zon LI, Daley GQ. Drug discovery for Diamond-Blackfan anemia using reprogrammed hematopoietic progenitors. Sci Transl Med. 2017 02 08; 9(376). View abstract
  6. Li H, Sieff C. Characteristic peripheral blood smear findings in disorders of cobalamin metabolism. Blood. 2016 11 24; 128(21):2584. View abstract
  7. Jabara HH, Boyden SE, Chou J, Ramesh N, Massaad MJ, Benson H, Bainter W, Fraulino D, Rahimov F, Sieff C, Liu ZJ, Alshemmari SH, Al-Ramadi BK, Al-Dhekri H, Arnaout R, Abu-Shukair M, Vatsayan A, Silver E, Ahuja S, Davies EG, Sola-Visner M, Ohsumi TK, Andrews NC, Notarangelo LD, Fleming MD, Al-Herz W, Kunkel LM, Geha RS. A missense mutation in TFRC, encoding transferrin receptor 1, causes combined immunodeficiency. Nat Genet. 2016 Jan; 48(1):74-8. View abstract
  8. Ludwig LS, Gazda HT, Eng JC, Eichhorn SW, Thiru P, Ghazvinian R, George TI, Gotlib JR, Beggs AH, Sieff CA, Lodish HF, Lander ES, Sankaran VG. Altered translation of GATA1 in Diamond-Blackfan anemia. Nat Med. 2014 Jul; 20(7):748-53. View abstract
  9. Williams DA, Bennett C, Bertuch A, Bessler M, Coates T, Corey S, Dror Y, Huang J, Lipton J, Olson TS, Reiss UM, Rogers ZR, Sieff C, Vlachos A, Walkovich K, Wang W, Shimamura A. Diagnosis and treatment of pediatric acquired aplastic anemia (AAA): an initial survey of the North American Pediatric Aplastic Anemia Consortium (NAPAAC). Pediatr Blood Cancer. 2014 May; 61(5):869-74. View abstract
  10. Landowski M, O'Donohue MF, Buros C, Ghazvinian R, Montel-Lehry N, Vlachos A, Sieff CA, Newburger PE, Niewiadomska E, Matysiak M, Glader B, Atsidaftos E, Lipton JM, Beggs AH, Gleizes PE, Gazda HT. Novel deletion of RPL15 identified by array-comparative genomic hybridization in Diamond-Blackfan anemia. Hum Genet. 2013 Nov; 132(11):1265-74. View abstract
  11. Sankaran VG, Ghazvinian R, Do R, Thiru P, Vergilio JA, Beggs AH, Sieff CA, Orkin SH, Nathan DG, Lander ES, Gazda HT. Exome sequencing identifies GATA1 mutations resulting in Diamond-Blackfan anemia. J Clin Invest. 2012 Jul; 122(7):2439-43. View abstract
  12. Gazda HT, Preti M, Sheen MR, O'Donohue MF, Vlachos A, Davies SM, Kattamis A, Doherty L, Landowski M, Buros C, Ghazvinian R, Sieff CA, Newburger PE, Niewiadomska E, Matysiak M, Glader B, Atsidaftos E, Lipton JM, Gleizes PE, Beggs AH. Frameshift mutation in p53 regulator RPL26 is associated with multiple physical abnormalities and a specific pre-ribosomal RNA processing defect in diamond-blackfan anemia. Hum Mutat. 2012 Jul; 33(7):1037-44. View abstract
  13. Crétien A, Proust A, Delaunay J, Rincé P, Leblanc T, Ducrocq R, Simansour M, Marie I, Tamary H, Meerpohl J, Niemeyer C, Gazda H, Sieff C, Ball S, Tchernia G, Mohandas N, Da Costa L. Genetic variants in the noncoding region of RPS19 gene in Diamond-Blackfan anemia: potential implications for phenotypic heterogeneity. Am J Hematol. 2010 Feb; 85(2):111-6. View abstract
  14. Doherty L, Sheen MR, Vlachos A, Choesmel V, O'Donohue MF, Clinton C, Schneider HE, Sieff CA, Newburger PE, Ball SE, Niewiadomska E, Matysiak M, Glader B, Arceci RJ, Farrar JE, Atsidaftos E, Lipton JM, Gleizes PE, Gazda HT. Ribosomal protein genes RPS10 and RPS26 are commonly mutated in Diamond-Blackfan anemia. Am J Hum Genet. 2010 Feb 12; 86(2):222-8. View abstract
  15. Sieff CA, Yang J, Merida-Long LB, Lodish HF. Pathogenesis of the erythroid failure in Diamond Blackfan anaemia. Br J Haematol. 2010 Feb; 148(4):611-22. View abstract
  16. Gazda HT, Sheen MR, Vlachos A, Choesmel V, O'Donohue MF, Schneider H, Darras N, Hasman C, Sieff CA, Newburger PE, Ball SE, Niewiadomska E, Matysiak M, Zaucha JM, Glader B, Niemeyer C, Meerpohl JJ, Atsidaftos E, Lipton JM, Gleizes PE, Beggs AH. Ribosomal protein L5 and L11 mutations are associated with cleft palate and abnormal thumbs in Diamond-Blackfan anemia patients. Am J Hum Genet. 2008 Dec; 83(6):769-80. View abstract
  17. Farrar JE, Nater M, Caywood E, McDevitt MA, Kowalski J, Takemoto CM, Talbot CC, Meltzer P, Esposito D, Beggs AH, Schneider HE, Grabowska A, Ball SE, Niewiadomska E, Sieff CA, Vlachos A, Atsidaftos E, Ellis SR, Lipton JM, Gazda HT, Arceci RJ. Abnormalities of the large ribosomal subunit protein, Rpl35a, in Diamond-Blackfan anemia. Blood. 2008 Sep 01; 112(5):1582-92. View abstract
  18. Gazda HT, Grabowska A, Merida-Long LB, Latawiec E, Schneider HE, Lipton JM, Vlachos A, Atsidaftos E, Ball SE, Orfali KA, Niewiadomska E, Da Costa L, Tchernia G, Niemeyer C, Meerpohl JJ, Stahl J, Schratt G, Glader B, Backer K, Wong C, Nathan DG, Beggs AH, Sieff CA. Ribosomal protein S24 gene is mutated in Diamond-Blackfan anemia. Am J Hum Genet. 2006 Dec; 79(6):1110-8. View abstract
  19. Gazda HT, Sieff CA. Recent insights into the pathogenesis of Diamond-Blackfan anaemia. Br J Haematol. 2006 Oct; 135(2):149-57. View abstract
  20. Gazda HT, Kho AT, Sanoudou D, Zaucha JM, Kohane IS, Sieff CA, Beggs AH. Defective ribosomal protein gene expression alters transcription, translation, apoptosis, and oncogenic pathways in Diamond-Blackfan anemia. Stem Cells. 2006 Sep; 24(9):2034-44. View abstract
  21. Quigley JG, Gazda H, Yang Z, Ball S, Sieff CA, Abkowitz JL. Investigation of a putative role for FLVCR, a cytoplasmic heme exporter, in Diamond-Blackfan anemia. Blood Cells Mol Dis. 2005 Sep-Oct; 35(2):189-92. View abstract
  22. Ebert BL, Lee MM, Pretz JL, Subramanian A, Mak R, Golub TR, Sieff CA. An RNA interference model of RPS19 deficiency in Diamond-Blackfan anemia recapitulates defective hematopoiesis and rescue by dexamethasone: identification of dexamethasone-responsive genes by microarray. Blood. 2005 Jun 15; 105(12):4620-6. View abstract
  23. Shikama Y, Shichishima T, Matsuoka I, Jubinsky PT, Sieff CA, Maruyama Y. Accumulation of an intron-retained mRNA for granulocyte macrophage-colony stimulating factor receptor common beta chain in neutrophils of myelodysplastic syndromes. J Leukoc Biol. 2005 May; 77(5):811-9. View abstract
  24. Gazda HT, Zhong R, Long L, Niewiadomska E, Lipton JM, Ploszynska A, Zaucha JM, Vlachos A, Atsidaftos E, Viskochil DH, Niemeyer CM, Meerpohl JJ, Rokicka-Milewska R, Pospisilova D, Wiktor-Jedrzejczak W, Nathan DG, Beggs AH, Sieff CA. RNA and protein evidence for haplo-insufficiency in Diamond-Blackfan anaemia patients with RPS19 mutations. Br J Haematol. 2004 Oct; 127(1):105-13. View abstract
  25. Gazda H, Lipton JM, Willig TN, Ball S, Niemeyer CM, Tchernia G, Mohandas N, Daly MJ, Ploszynska A, Orfali KA, Vlachos A, Glader BE, Rokicka-Milewska R, Ohara A, Baker D, Pospisilova D, Webber A, Viskochil DH, Nathan DG, Beggs AH, Sieff CA. Evidence for linkage of familial Diamond-Blackfan anemia to chromosome 8p23.3-p22 and for non-19q non-8p disease. Blood. 2001 Apr 01; 97(7):2145-50. View abstract
  26. Sieff CA, Nisbet-Brown E, Nathan DG. Congenital bone marrow failure syndromes. Br J Haematol. 2000 Oct; 111(1):30-42. View abstract
  27. Willig TN, Gazda H, Sieff CA. Diamond-Blackfan anemia. Curr Opin Hematol. 2000 Mar; 7(2):85-94. View abstract
  28. Kung AL, Rebel VI, Bronson RT, Ch'ng LE, Sieff CA, Livingston DM, Yao TP. Gene dose-dependent control of hematopoiesis and hematologic tumor suppression by CBP. Genes Dev. 2000 Feb 01; 14(3):272-7. View abstract
  29. Rebel VI, Hartnett S, Denham J, Chan M, Finberg R, Sieff CA. Maturation and lineage-specific expression of the coxsackie and adenovirus receptor in hematopoietic cells. Stem Cells. 2000; 18(3):176-82. View abstract
  30. Rebel VI, Hartnett S, Hill GR, Lazo-Kallanian SB, Ferrara JL, Sieff CA. Essential role for the p55 tumor necrosis factor receptor in regulating hematopoiesis at a stem cell level. J Exp Med. 1999 Nov 15; 190(10):1493-504. View abstract
  31. Nathan DG, Sieff CA. Pure red-cell aplasia. N Engl J Med. 1999 Jun 24; 340(25):2004; author reply 2005. View abstract
  32. Rebel VI, Tanaka M, Lee JS, Hartnett S, Pulsipher M, Nathan DG, Mulligan RC, Sieff CA. One-day ex vivo culture allows effective gene transfer into human nonobese diabetic/severe combined immune-deficient repopulating cells using high-titer vesicular stomatitis virus G protein pseudotyped retrovirus. Blood. 1999 Apr 01; 93(7):2217-24. View abstract
  33. Taylor DS, Lee Y, Sieff CA, Homans A, Garrison L, Guinan EC. Phase I/II trial of PIXY321 (granulocyte-macrophage colony stimulating factor/interleukin-3 fusion protein) for treatment of inherited and acquired marrow failure syndromes. Br J Haematol. 1998 Nov; 103(2):304-7. View abstract
  34. Pulsipher M, Kupfer GM, Naf D, Suliman A, Lee JS, Jakobs P, Grompe M, Joenje H, Sieff C, Guinan E, Mulligan R, D'Andrea AD. Subtyping analysis of Fanconi anemia by immunoblotting and retroviral gene transfer. Mol Med. 1998 Jul; 4(7):468-79. View abstract
  35. Aiuti A, Friedrich C, Sieff CA, Gutierrez-Ramos JC. Identification of distinct elements of the stromal microenvironment that control human hematopoietic stem/progenitor cell growth and differentiation. Exp Hematol. 1998 Feb; 26(2):143-57. View abstract
  36. Krijanovski OI, Sieff CA. Diamond-Blackfan anemia. Hematol Oncol Clin North Am. 1997 Dec; 11(6):1061-77. View abstract
  37. Goodell MA, Rosenzweig M, Kim H, Marks DF, DeMaria M, Paradis G, Grupp SA, Sieff CA, Mulligan RC, Johnson RP. Dye efflux studies suggest that hematopoietic stem cells expressing low or undetectable levels of CD34 antigen exist in multiple species. Nat Med. 1997 Dec; 3(12):1337-45. View abstract
  38. Jubinsky PT, Krijanovski OI, Nathan DG, Tavernier J, Sieff CA. The beta chain of the interleukin-3 receptor functionally associates with the erythropoietin receptor. Blood. 1997 Sep 01; 90(5):1867-73. View abstract
  39. Benjamin RJ, Linsley L, Fountain D, Churchill WH, Sieff C, Cannon ME, Uhl L, Gaynes L, Antin JH, Wheeler C. Preapheresis peripheral blood CD34+ mononuclear cell counts as predictors of progenitor cell yield. Transfusion. 1997 Jan; 37(1):79-85. View abstract
  40. Chen L, Pulsipher M, Chen D, Sieff C, Elias A, Fine HA, Kufe DW. Selective transgene expression for detection and elimination of contaminating carcinoma cells in hematopoietic stem cell sources. J Clin Invest. 1996 Dec 01; 98(11):2539-48. View abstract
  41. Jubinsky PT, Shikama Y, Laurie A, Nathan DG, Carroll M, Sieff CA. The beta c component of the granulocyte-macrophage colony-stimulating factor (GM-CSF)/interleukin 3 (IL-3)/IL-5 receptor interacts with a hybrid GM-CSF/erythropoietin receptor to influence proliferation and beta-globin mRNA expression. Mol Med. 1996 Nov; 2(6):766-73. View abstract
  42. Shikama Y, Barber DL, D'Andrea AD, Sieff CA. A constitutively activated chimeric cytokine receptor confers factor-independent growth in hematopoietic cell lines. Blood. 1996 Jul 15; 88(2):455-64. View abstract
  43. Gribben JG, Guinan EC, Boussiotis VA, Ke XY, Linsley L, Sieff C, Gray GS, Freeman GJ, Nadler LM. Complete blockade of B7 family-mediated costimulation is necessary to induce human alloantigen-specific anergy: a method to ameliorate graft-versus-host disease and extend the donor pool. Blood. 1996 Jun 01; 87(11):4887-93. View abstract
  44. Pratt JC, Weiss M, Sieff CA, Shoelson SE, Burakoff SJ, Ravichandran KS. Evidence for a physical association between the Shc-PTB domain and the beta c chain of the granulocyte-macrophage colony-stimulating factor receptor. J Biol Chem. 1996 May 24; 271(21):12137-40. View abstract
  45. Benjamin RJ, Linsley L, Axelrod JD, Churchill WH, Sieff C, Shulman LN, Elias A, Ayash L, Malachowski ME, Uhl L, et al. The collection and evaluation of peripheral blood progenitor cells sufficient for repetitive cycles of high-dose chemotherapy support. Transfusion. 1995 Oct; 35(10):837-44. View abstract
  46. Blobel GA, Sieff CA, Orkin SH. Ligand-dependent repression of the erythroid transcription factor GATA-1 by the estrogen receptor. Mol Cell Biol. 1995 Jun; 15(6):3147-53. View abstract
  47. Busque L, Gilliland DG, Prchal JT, Sieff CA, Weinstein HJ, Sokol JM, Belickova M, Wayne AS, Zuckerman KS, Sokol L, et al. Clonality in juvenile chronic myelogenous leukemia. Blood. 1995 Jan 01; 85(1):21-30. View abstract
  48. Jubinsky PT, Laurie AS, Nathan DG, Yetz-Aldepe J, Sieff CA. Expression and function of the human granulocyte-macrophage colony-stimulating factor receptor alpha subunit. Blood. 1994 Dec 15; 84(12):4174-85. View abstract
  49. Sieff CA. Hematopoietic cell proliferation and differentiation. Curr Opin Hematol. 1994 Jul; 1(4):310-20. View abstract
  50. Neben S, Donaldson D, Sieff C, Mauch P, Bodine D, Ferrara J, Yetz-Aldape J, Turner K. Synergistic effects of interleukin-11 with other growth factors on the expansion of murine hematopoietic progenitors and maintenance of stem cells in liquid culture. Exp Hematol. 1994 Apr; 22(4):353-9. View abstract
  51. Nathan DH, Sieff CA. [Regulation of hematopoiesis]. Gematol Transfuziol. 1994 Mar-Apr; 39(2):3-10. View abstract
  52. Weiss M, Yokoyama C, Shikama Y, Naugle C, Druker B, Sieff CA. Human granulocyte-macrophage colony-stimulating factor receptor signal transduction requires the proximal cytoplasmic domains of the alpha and beta subunits. Blood. 1993 Dec 01; 82(11):3298-306. View abstract
  53. Sieff C, Guinan E. In vitro enhancement of erythropoiesis by steel factor in Diamond-Blackfan anemia and treatment of other congenital cytopenias with recombinant interleukin 3/granulocyte-macrophage colony stimulating factor. Stem Cells. 1993 Jul; 11 Suppl 2:113-22. View abstract
  54. Jubinsky PT, Nathan DG, Wilson DJ, Sieff CA. A low-affinity human granulocyte-macrophage colony-stimulating factor/murine erythropoietin hybrid receptor functions in murine cell lines. Blood. 1993 Feb 01; 81(3):587-91. View abstract
  55. Sieff CA, Yokoyama CT, Zsebo KM, Trammell J, Andersen JW, Nathan DG, Williams DA. The production of steel factor mRNA in Diamond-Blackfan anaemia long-term cultures and interactions of steel factor with erythropoietin and interleukin-3. Br J Haematol. 1992 Dec; 82(4):640-7. View abstract
  56. Antin JH, Bierer BE, Smith BR, Ferrara J, Guinan EC, Sieff C, Golan DE, Macklis RM, Tarbell NJ, Lynch E, et al. Selective depletion of bone marrow T lymphocytes with anti-CD5 monoclonal antibodies: effective prophylaxis for graft-versus-host disease in patients with hematologic malignancies. Blood. 1991 Oct 15; 78(8):2139-49. View abstract
  57. McCarthy PL, Abhyankar S, Neben S, Newman G, Sieff C, Thompson RC, Burakoff SJ, Ferrara JL. Inhibition of interleukin-1 by an interleukin-1 receptor antagonist prevents graft-versus-host disease. Blood. 1991 Oct 15; 78(8):1915-8. View abstract
  58. Sieff CA. New hats for hematopoietic hormones. Exp Hematol. 1991 Oct; 19(9):857-60. View abstract
  59. Crosier KE, Wong GG, Mathey-Prevot B, Nathan DG, Sieff CA. A functional isoform of the human granulocyte/macrophage colony-stimulating factor receptor has an unusual cytoplasmic domain. Proc Natl Acad Sci U S A. 1991 Sep 01; 88(17):7744-8. View abstract
  60. Ezekowitz RA, Sieff CA, Dinauer MC, Nathan DG, Orkin SH, Newburger PE. Restoration of phagocyte function by interferon-gamma in X-linked chronic granulomatous disease occurs at the level of a progenitor cell. Blood. 1990 Dec 15; 76(12):2443-8. View abstract
  61. Guinan EC, Sieff CA, Oette DH, Nathan DG. A phase I/II trial of recombinant granulocyte-macrophage colony-stimulating factor for children with aplastic anemia. Blood. 1990 Sep 15; 76(6):1077-82. View abstract
  62. Sieff CA. Biology and clinical aspects of the hematopoietic growth factors. Annu Rev Med. 1990; 41:483-96. View abstract
  63. Niemeyer CM, Sieff CA, Smith BR, Ault KA, Nathan DG. Hematopoiesis in vitro coexists with natural killer lymphocytes. Blood. 1989 Nov 15; 74(7):2376-82. View abstract
  64. Wimperis JZ, Niemeyer CM, Sieff CA, Mathey-Prevot B, Nathan DG, Arceci RJ. Granulocyte-macrophage colony-stimulating factor and interleukin-3 mRNAs are produced by a small fraction of blood mononuclear cells. Blood. 1989 Oct; 74(5):1525-30. View abstract
  65. Niemeyer CM, Sieff CA, Mathey-Prevot B, Wimperis JZ, Bierer BE, Clark SC, Nathan DG. Expression of human interleukin-3 (multi-CSF) is restricted to human lymphocytes and T-cell tumor lines. Blood. 1989 Mar; 73(4):945-51. View abstract
  66. Sieff CA, Ekern SC, Nathan DG, Anderson JW. Combinations of recombinant colony-stimulating factors are required for optimal hematopoietic differentiation in serum-deprived culture. Blood. 1989 Feb 15; 73(3):688-93. View abstract
  67. Sieff CA, Niemeyer CM, Mentzer SJ, Faller DV. Interleukin-1, tumor necrosis factor, and the production of colony-stimulating factors by cultured mesenchymal cells. Blood. 1988 Oct; 72(4):1316-23. View abstract
  68. Sieff CA, Niemeyer CM. The biology of the colony stimulating factors. Behring Inst Mitt. 1988 Aug; (83):93-7. View abstract
  69. Sieff CA, Niemeyer CM, Faller DV. Human colony-stimulating factors and stromal cell function. Soc Gen Physiol Ser. 1988; 43:47-55. View abstract
  70. Sieff CA, Ekern S, Nathan DG. Combinations of purified recombinant colony-stimulating factors are required for optimal hematopoietic differentiation. Trans Assoc Am Physicians. 1988; 101:282-7. View abstract
  71. Sieff CA. The sources and actions of the human colony stimulating factors. Mead Johnson Symp Perinat Dev Med. 1988; (32):21-7. View abstract
  72. Emerson SG, Sieff CA, Gross RG, Rozans MK, Miller RA, Rappeport JM, Nathan DG. Decreased hematopoietic accessory cell function following bone marrow transplantation. Exp Hematol. 1987 Nov; 15(10):1013-21. View abstract
  73. Sieff CA, Niemeyer CM, Nathan DG, Ekern SC, Bieber FR, Yang YC, Wong G, Clark SC. Stimulation of human hematopoietic colony formation by recombinant gibbon multi-colony-stimulating factor or interleukin 3. J Clin Invest. 1987 Sep; 80(3):818-23. View abstract
  74. Miller BA, Perrine SP, Antognetti G, Perlmutter DH, Emerson SG, Sieff C, Faller DV. Gamma-interferon alters globin gene expression in neonatal and adult erythroid cells. Blood. 1987 Jun; 69(6):1674-81. View abstract
  75. Sieff CA. Hematopoietic growth factors. J Clin Invest. 1987 Jun; 79(6):1549-57. View abstract
  76. Tsai S, Patel V, Beaumont E, Lodish HF, Nathan DG, Sieff CA. Differential binding of erythroid and myeloid progenitors to fibroblasts and fibronectin. Blood. 1987 Jun; 69(6):1587-94. View abstract
  77. Sieff CA, Niemeyer CM, Faller DV. The production of hematopoietic growth factors by endothelial accessory cells. Blood Cells. 1987; 13(1-2):65-74. View abstract
  78. Sieff CA, Tsai S, Faller DV. Interleukin 1 induces cultured human endothelial cell production of granulocyte-macrophage colony-stimulating factor. J Clin Invest. 1987 Jan; 79(1):48-51. View abstract
  79. Nathan DG, Sieff CA. The biological activities and uses of recombinant granulocyte-macrophage and multi-colony stimulating factors. Prog Hematol. 1987; 15:1-18. View abstract
  80. Sieff CA, Niemeyer CM, Faller DV. The role of endothelial cells in hematopoiesis. Prog Clin Biol Res. 1987; 251:13-21. View abstract
  81. Arnaout MA, Wang EA, Clark SC, Sieff CA. Human recombinant granulocyte-macrophage colony-stimulating factor increases cell-to-cell adhesion and surface expression of adhesion-promoting surface glycoproteins on mature granulocytes. J Clin Invest. 1986 Aug; 78(2):597-601. View abstract
  82. Tsai S, Sieff CA, Nathan DG. Stromal cell-associated erythropoiesis. Blood. 1986 May; 67(5):1418-26. View abstract
  83. Tsai S, Emerson SG, Sieff CA, Nathan DG. Isolation of a human stromal cell strain secreting hemopoietic growth factors. J Cell Physiol. 1986 Apr; 127(1):137-45. View abstract
  84. Morgan G, Linch DC, Knott LT, Davies EG, Sieff C, Chessells JM, Hale G, Waldmann H, Levinsky RJ. Successful haploidentical mismatched bone marrow transplantation in severe combined immunodeficiency: T cell removal using CAMPATH-I monoclonal antibody and E-rosetting. Br J Haematol. 1986 Mar; 62(3):421-30. View abstract
  85. Sieff CA. Membrane antigen expression during hemopoietic differentiation. Crit Rev Oncol Hematol. 1986; 5(1):1-36. View abstract
  86. Sieff CA, Emerson SG, Mufson A, Gesner TG, Nathan DG. Dependence of highly enriched human bone marrow progenitors on hemopoietic growth factors and their response to recombinant erythropoietin. J Clin Invest. 1986 Jan; 77(1):74-81. View abstract
  87. Sieff CA, Emerson SG, Donahue RE, Nathan DG, Wang EA, Wong GG, Clark SC. Human recombinant granulocyte-macrophage colony-stimulating factor: a multilineage hematopoietin. Science. 1985 Dec 06; 230(4730):1171-3. View abstract
  88. Emerson SG, Sieff CA, Wang EA, Wong GG, Clark SC, Nathan DG. Purification of fetal hematopoietic progenitors and demonstration of recombinant multipotential colony-stimulating activity. J Clin Invest. 1985 Sep; 76(3):1286-90. View abstract
  89. Greaves MF, Katz FE, Myers CD, Davies L, Sieff C. Selective expression of cell surface antigens on human haemopoietic progenitor cells. Prog Clin Biol Res. 1985; 184:301-15. View abstract
  90. Sieff C. Pure red cell aplasia. Br J Haematol. 1983 Jul; 54(3):331-6. View abstract
  91. Greaves MF, Sieff C, Edwards PA. Monoclonal antiglycophorin as a probe for erythroleukemias. Blood. 1983 Apr; 61(4):645-51. View abstract
  92. Sieff CA, Chessells JM, Levinsky RJ, Pritchard J, Rogers DW, Casey A, Muller K, Hall CM. Allogeneic bone-marrow transplantation in infantile malignant osteopetrosis. Lancet. 1983 Feb 26; 1(8322):437-41. View abstract
  93. Chessells JM, Sieff CA, Rankin A. Acute myeloid leukaemia in childhood: treatment in the United Kingdom. Haematol Blood Transfus. 1983; 28:51-5. View abstract
  94. Sieff C, Bicknell D, Caine G, Edwards PA, Greaves M. Antigen expression on normal and leukaemic erythroid precursors. Haematol Blood Transfus. 1983; 28:397-402. View abstract
  95. Sieff C, Bicknell D, Caine G, Robinson J, Lam G, Greaves MF. Changes in cell surface antigen expression during hemopoietic differentiation. Blood. 1982 Sep; 60(3):703-13. View abstract
  96. Masucci MG, Szigeti R, Ernberg I, Masucci G, Klein G, Chessels J, Sieff C, Lie S, Glomstein A, Businco L, Henle W, Henle G, Pearson G, Sakamoto K, Purtilo DT. Cellular immune defects to Epstein-Barr virus-determined antigens in young males. Cancer Res. 1981 Nov; 41(11 Pt 1):4284-91. View abstract
  97. Purtilo DT, Sakamoto K, Saemundsen AK, Sullivan JL, Synnerholm AC, Anvret M, Pritchard J, Sloper C, Sieff C, Pincott J, Pachman L, Rich K, Cruzi F, Cornet JA, Collins R, Barnes N, Knight J, Sandstedt B, Klein G. Documentation of Epstein-Barr virus infection in immunodeficient patients with life-threatening lymphoproliferative diseases by clinical, virological, and immunopathological studies. Cancer Res. 1981 Nov; 41(11 Pt 1):4226-36. View abstract
  98. Sieff CA, Chessells JM, Harvey BA, Pickthall VJ, Lawler SD. Monosomy 7 in childhood: a myeloproliferative disorder. Br J Haematol. 1981 Oct; 49(2):235-49. View abstract
  99. Robinson J, Sieff C, Delia D, Edwards PA, Greaves M. Expression of cell-surface HLA-DR, HLA-ABC and glycophorin during erythroid differentiation. Nature. 1981 Jan 01; 289(5793):68-71. View abstract
  100. Greaves M, Robinson J, Delia D, Sutherland R, Newman R, Sieff C. Mapping cell surface antigen expression of haemopoietic progenitor cells using monoclonal antibodies. Ciba Found Symp. 1981; 84:109-29. View abstract
  101. Linch DC, Cawley JC, MacDonald SM, Masters G, Roberts BE, Antonis AH, Waters AK, Sieff C, Lydyard PM. Acquired pure red-cell aplasia associated with an increase of T cells bearing receptors for the Fc of IgG. Acta Haematol. 1981; 65(4):270-4. View abstract
  102. Greaves MF, Robinson JB, Delia D, Ritz J, Schlossman S, Sieff C, Goldstein G, Kung P, Bollum FJ, Edwards PA. Comparative antigenic phenotypes of normal and leukemic hemopoietic precursor cells analysed with a "library" of monoclonal antibodies. Haematol Blood Transfus. 1981; 26:296-304. View abstract
  103. Sieff CA, Malleson P. Familial myelofibrosis. Arch Dis Child. 1980 Nov; 55(11):888-93. View abstract
  104. Sieff CA, Chessells JM. The response of a child with primary sideroblastic anemia to cyclophosphamide. Blood. 1980 Aug; 56(2):323. View abstract
  105. Torok-Storb BJ, Sieff C, Storb R, Adamson J, Thomas ED. In vitro tests for distinguishing possible immune-mediated aplastic anemia from transfusion-induced sensitization. Blood. 1980 Feb; 55(2):211-5. View abstract