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Jay Wilson
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Jay  Wilson, MD

Department: General Surgery
Research Centers: General Surgery Research Center
Hospital Title: Director, Lung Growth Laboratory Director, Surgical Critical Care Senior Associate in Surgery
Academic Title: Associate Professor of Surgery
Research Area: Fetal and neonatal lung growth
Congenital lung growth

Research Overview

The focus of Jay Wilson's research is to increase lung capacity in children who are born with underdeveloped lungs due to conditions such as congenital diaphragmatic hernia. He pioneered the use of perfluorocarbon--an oxygen-dissolving liquid--to stretch the lungs of premature infants who had difficulty being weaned from ECMO.

Recently, his focus has turned to elucidating the molecular process of fetal and neonatal lung growth, so that these processes might be harnessed to stimulate lung growth in children with congenital disorders.

About Jay Wilson

Jay Wilson received his BS degree from the University of Massachusetts at Amherst, his MS degree from MIT and his MD degree from Albert Einstein College of Medicine. He completed his surgical internship and residency at Brigham and Women's Hospital and his Pediatric Surgical fellowship at Boston Children's Hospital. He is board certified in Surgery, Surgical Critical Care and Pediatric Surgery.

Key Publications

(For a complete list of articles on PubMed.org authored or co-authored by Dr. Wilson, click here.)

  • Friedman S, Chen C, Chapman JS, Jeruss S, Terrin N, Tighiouart H, Parsons SK, Wilson JM. Neurodevelopmental outcomes of congenital diaphragmatic hernia survivors followed in a multidisciplinary clinic at ages 1 and 3. J Pediatr Surg. 2008 Jun; 43(6): 1035-43.
     
  • Congenital Diaphragmatic Hernia Study Group, Lally KP, Lally PA, Lasky RE, Tibboel D, Jaksic T, Wilson JM, Frenckner B, Van Meurs KP, Bohn DJ, Davis CF, Hirschl RB. Defect size determines survival in infants with congenital diaphragmatic hernia. Pediatrics. 2007 Sep; 120(3): e651-657.
     
  • Vascular endothelial growth factor accelerates compensatory lung growth after unilateral pneumonectomy. Am J Physiol Lung Cell Mol Physiol. 2007 Mar; 292(3): L742-747.
     
  • Hayward MJ, Kharasch V, Sheils C, Friedman S, Dunleavy MJ, Utter S, Zurakowski D, Jennings R, Wilson JM. Predicting inadequate long-term lung development in children with congenital diaphragmatic hernia: an analysis of longitudinal changes in ventilation and perfusion. J Pediatr Surg. 2007 Jan; 42(1): 112-116.

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