Michael Scott is studying moyamoya syndrome in children, a disease which leads to progressive strokes. His laboratory is evaluating various molecular compounds and growth factors in the cerebrospinal fluid (CSF) and blood, which may indicate the potential course of the disease and provide clues to its etiology and/or treatment.
The principal goals of Scott and his colleagues are to:
- Determine the etiology of stroke syndromes (moyamoya syndrome) in children.
- Determine if nonsurgical treatments for moyamoya syndrome are reasonable options based on the pharmacologic information derived from their studies.
- Modify present surgical options to take advantage of their discoveries.
About Michael Scott
Michael Scott received an MD degree from Temple University School of Medicine. He completed an internship at Boston City Hospital, a residency in neurosurgery at Massachusetts General Hospital, and a research fellowship at the National Institute of Neurological Diseases and Stroke.
He is Chairman of the American Board of Pediatric Neurological Surgery, Past President of the American Society of Pediatric Neurosurgeons, and Past Vice-Chairman of The American Board of Neurological Surgery.
- Malek AM, Connors S, Robertson RL, Folkman J, Scott RM. Elevation of cerebrospinal fluid levels of basic fibroblast growth factor in moyamoya and central nervous system disorders. Pediatr Neurosurgery 1997; 27: 182-189.
- Soriano SG, Cowan DB, Proctor MR, Scott RM. Levels of soluble adhesion molecules are elevated in the cerebrospinal fluid of children with moyamoya syndrome. Neurosurgery 2002; 50: 544-549.
- Scott RM, Smith JL, Robertson RL, Madsen JR, Soriano SG, Rockoff MA. Long-term outcome in children with moyamoya syndrome after cranial revascularization by pial synangiosis. Journal of Neurosurgery: Pediatrics 2004; 100: 142-149.