Tissue Engineering holds great promise in regenerative medicine as an alternative approach to replace diseased and damaged tissues. A challenge in tissue engineering is to generate tissues with a functional vascular bed. Our lab is interested in developing cell-based strategies to generate both vascular networks and vascularized tissues using human postnatal cells.
About Juan Melero-Martin
Dr. Melero-Martin graduated in Chemical Engineering from University of Sevilla, Spain, in 1998. He went on to earn a PhD in biochemical engineering from University of Birmingham, UK in 2005. Dr. Melero-Martin's doctoral research focused on cartilage tissue engineering, and was sponsored by Smith & Nephew. From 2005 to 2008, he trained as a post-doctoral fellow in the Vascular Biology Program at Children's Hospital in Boston. He joined the Department of Cardiac Surgery at Children's Hospital in 2008. In 2009, he received a K99/R00 Pathway to Independence Award from the NIH.
- Induction of erythropoiesis using human vascular networks genetically-engineered for controlled erythropoietin release. Lin RZ, Dreyzin A, Aamodt K, Li D, Jaminet SCS, Dudley AC, Melero-Martin JM. Blood 2011; 118(20):5420-8 PDF
- Engineering robust and functional vascular networks in vivo with human adult and cord blood-derived progenitor cells. Melero-Martin JM, De Obaldia ME, Kang SY, Khan ZA, Yuan L, Oettgen P, Bischoff J. Circ Res 2008; 103(2): 194-202. PDF
- In vivo vasculogenic potential of human blood-derived endothelial progenitor cells. Melero-Martin JM, Khan ZA, Picard A, Wu X, Paruchuri S, Bischoff J. Blood 2007; 109(11): 4761-8. PDF
see all publications in PubMed