Sara O.  Vargas , MD

Sara O. Vargas, MD

Director, Patient Safety and Quality; Staff Pathologist

Associate Professor of Pathology, Harvard Medical School

    Contact: 617-355-7431
  • Fax: 617-730-0207

Medical Services


  • Pathology
  • Pulmonary Pathology


To schedule an appointment: Call 617-355-7431

Experience and Education


Undergraduate, A.B. cum laude

Harvard University, 1988

Cambridge, MA

Medical School

University of Vermont College of Medicine, 1994

Burlington, VT

Residency, Anatomic and Clinical Pathology

Brigham and Women's Hospital, 1998

Boston, MA

Fellowship, Pediatric Pathology

Boston Children's Hospital, 1999

Boston, MA


  • American Board of Pathology, Pathology-Anatomic/Pathology-Clinical, Pathology-Pediatric



Publications powered by Harvard Catalyst Profiles
  1. Dixit A, Alexandrescu S, Boyer D, Graf EH, Vargas SO, Silverman M. Mycoplasma hominis Empyema in an 18-Year-old Stem Cell and Lung Transplant Recipient: Case Report and Review of the Literature. J Pediatric Infect Dis Soc. 2017 Nov 24; 6(4):e173-e176.
  2. Kovach AE, Magcalas PM, Ireland C, McEnany K, Oliveira AM, Kieran MW, Baird CW, Jenkins K, Vargas SO. Paucicellular Fibrointimal Proliferation Characterizes Pediatric Pulmonary Vein Stenosis: Clinicopathologic Analysis of 213 Samples From 97 Patients. Am J Surg Pathol. 2017 Sep; 41(9):1198-1204.
  3. Sriram G, Zendejas B, Vargas SO, Chen C. Colonic mesenteric lymphatic malformation presenting as an intraabdominal abscess in an infant: A case report. Int J Surg Case Rep. 2017; 39:154-158.
  4. Vadva Z, Nurko S, Hehn R, Vargas SO. Rectal Suction Biopsy in Patients With Previous Anorectal Surgery for Hirschsprung Disease. J Pediatr Gastroenterol Nutr. 2017 Aug; 65(2):173-178.
  5. Torre M, Lechpammer M, Paulson V, Prabhu S, Marshall AC, Juraszek AL, Padera RF, Bundock EA, Vargas SO, Folkerth RD. Embolic Foreign Material in the Central Nervous System of Pediatric Autopsy Patients With Instrumented Heart Disease. J Neuropathol Exp Neurol. 2017 Jul 01; 76(7):571-577.
  6. Anderson ME, Wu JS, Vargas SO. CORR ® Tumor Board: Do Orthopaedic Oncologists Agree on the Diagnosis and Treatment of Cartilage Tumors of the Appendicular Skeleton? Clin Orthop Relat Res. 2017 09; 475(9):2172-2175.
  7. Anderson ME, Wu JS, Vargas SO. CORR ® Tumor Board: Is There Benefit to Free Over Pedicled Vascularized Grafts in Augmenting Tibial Intercalary Allograft Constructs? Clin Orthop Relat Res. 2017 05; 475(5):1319-1321.
  8. Siegele B, Roberts J, Black JO, Rudzinski E, Vargas SO, Galambos C. DUX4 Immunohistochemistry Is a Highly Sensitive and Specific Marker for CIC-DUX4 Fusion-positive Round Cell Tumor. Am J Surg Pathol. 2017 Mar; 41(3):423-429.
  9. Morton SU, Prabhu SP, Lidov HGW, Shi J, Anselm I, Brownstein CA, Bainbridge MN, Beggs AH, Vargas SO, Agrawal PB. AIFM1 mutation presenting with fatal encephalomyopathy and mitochondrial disease in an infant. Cold Spring Harb Mol Case Stud. 2017 Mar; 3(2):a001560.
  10. Alexandrescu S, Akhavanfard S, Harris MH, Vargas SO. Clinical, Pathologic, and Genetic Features of Wilms Tumors With WTX Gene Mutation. Pediatr Dev Pathol. 2017 Mar-Apr; 20(2):105-111.
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  12. Chung H, Lieberman TD, Vargas SO, Flett KB, McAdam AJ, Priebe GP, Kishony R. Global and local selection acting on the pathogen Stenotrophomonas maltophilia in the human lung. Nat Commun. 2017 Jan 19; 8:14078.
  13. Bailey E, Cui Y, Casey A, Stoler JM, Ai X, Ma D, Handin R, Sliz P, Vargas SO, El-Chemaly SY. Pulmonary Vasculopathy Associated with FIGF Gene Mutation. Am J Pathol. 2017 Jan; 187(1):25-32.
  14. Bairdain S, Zurakowski D, Vargas SO, Stenquist N, McDonald M, Towne MC, Miller DT, Jennings RW, Kantor DB, Agrawal PB. Long-Gap Esophageal Atresia Is a Unique Entity within the Esophageal Atresia Defect Spectrum. Neonatology. 2017; 111(2):140-144.
  15. Anderson ME, Wu JS, Vargas SO. CORR ® Tumor Board: What are the Functional Results, Complications, and Outcomes of Using a Custom Unipolar Wrist Hemiarthroplasty for Treatment of Grade III Giant Cell Tumors of the Distal Radius? Clin Orthop Relat Res. 2016 12; 474(12):2580-2582.
  16. Bertero T, Oldham WM, Cottrill KA, Pisano S, Vanderpool RR, Yu Q, Zhao J, Tai Y, Tang Y, Zhang YY, Rehman S, Sugahara M, Qi Z, Gorcsan J, Vargas SO, Saggar R, Saggar R, Wallace WD, Ross DJ, Haley KJ, Waxman AB, Parikh VN, De Marco T, Hsue PY, Morris A, Simon MA, Norris KA, Gaggioli C, Loscalzo J, Fessel J, Chan SY. Vascular stiffness mechanoactivates YAP/TAZ-dependent glutaminolysis to drive pulmonary hypertension. J Clin Invest. 2016 Sep 01; 126(9):3313-35.
  17. Thacker PG, Vargas SO, Fishman MP, Casey AM, Lee EY. Current Update on Interstitial Lung Disease of Infancy: New Classification System, Diagnostic Evaluation, Imaging Algorithms, Imaging Findings, and Prognosis. Radiol Clin North Am. 2016 Nov; 54(6):1065-1076.
  18. Saadat E, Vargas SO, Anderson M, Glotzbecker M. Pediatric Intra-Articular Localized Tenosynovial Giant Cell Tumor Presenting as an Acutely Irritable Hip: A Case Report. JBJS Case Connect. 2016 Jul-Sep; 6(3):e60.
  19. Anderson ME, Wu JS, Vargas SO. CORR (®) Tumor Board: Is Prophylactic Intervention More Cost-Effective than the Treatment of Pathologic Fractures in Metastatic Bone Disease? Clin Orthop Relat Res. 2016 07; 474(7):1560-2.
  20. Weil BR, Al-Ibraheemi A, Vargas SO, Rangel SJ. Autoamputation of the appendix presenting as a calcified abdominal mass following necrotizing enterocolitis. Pediatr Dev Pathol. 2016 Mar 28.
  21. Somers GR, Vargas SO, Coffin CM. Society for Pediatric Pathology Comment on Proposed Changes to Regulations on Research with Human Tissues (Docket ID#: HHS-OPHS-2015-0008). Pediatr Dev Pathol. 2016 Sep/Oct; 19(5):428-430.
  22. Ginat DT, Vargas SO, Silvera VM, Volk MS, Degar BA, Robson CD. Imaging Features of Juvenile Xanthogranuloma of the Pediatric Head and Neck. AJNR Am J Neuroradiol. 2016 May; 37(5):910-6.
  23. Alexandrescu S, Akhavanfard S, Harris MH, Vargas SO. Clinical, pathologic, and genetic features of Wilms tumors with WTX gene mutation. Pediatr Dev Pathol. 2016 Jan 04.
  24. Anderson ME, Wu JS, Vargas SO. CORR (®) Tumor Board: Does Microwave Ablation of the Tumor Edge Allow for Joint-sparing Surgery in Patients with Osteosarcoma of the Proximal Tibia? Clin Orthop Relat Res. 2016 May; 474(5):1110-2.
  25. Anderson ME, Wu JS, Vargas SO. CORR(®) Tumor Board: Sacral Insufficiency Fractures are Common After High-dose Radiation for Sacral Chordomas Treated With or Without Surgery. Clin Orthop Relat Res. 2016 Mar; 474(3):630-2.
  26. Vadva Z, Laufer MR, Weldon CB, Frazier AL, Vargas SO. Diagnostic Impact of Peritoneal Fluid Cytology in the Setting of Pediatric Uterine Adnexal Biopsy or Resection. Pediatr Dev Pathol. 2016 Sep/Oct; 19(5):401-408.
  27. Bertero T, Cottrill KA, Lu Y, Haeger CM, Dieffenbach P, Annis S, Hale A, Bhat B, Kaimal V, Zhang YY, Graham BB, Kumar R, Saggar R, Saggar R, Wallace WD, Ross DJ, Black SM, Fratz S, Fineman JR, Vargas SO, Haley KJ, Waxman AB, Chau BN, Fredenburgh LE, Chan SY. Matrix Remodeling Promotes Pulmonary Hypertension through Feedback Mechanoactivation of the YAP/TAZ-miR-130/301 Circuit. Cell Rep. 2015 Nov 03; 13(5):1016-32.
  28. Pogoriler JE, Kulik TJ, Casey AM, Baird CW, Mullen MP, Jenkins KJ, Vargas SO. Lung Pathology in Pediatric Pulmonary Vein Stenosis. Pediatr Dev Pathol. 2016 May-Jun; 19(3):219-29.
  29. Baez JC, Zurakowski D, Vargas SO, Lee EY. Incidental Thyroid Nodules Detected on Thoracic Contrast-Enhanced CT in the Pediatric Population: Prevalence and Outcomes. AJR Am J Roentgenol. 2015 Sep; 205(3):W360-5.
  30. Strychowsky JE, Vargas SO, Cohen E, Vielman R, Son MB, Rahbar R. Laryngeal sarcoidosis: presentation and management in the pediatric population. Int J Pediatr Otorhinolaryngol. 2015 Sep; 79(9):1382-7.
  31. White K, Lu Y, Annis S, Hale AE, Chau BN, Dahlman JE, Hemann C, Opotowsky AR, Vargas SO, Rosas I, Perrella MA, Osorio JC, Haley KJ, Graham BB, Kumar R, Saggar R, Saggar R, Wallace WD, Ross DJ, Khan OF, Bader A, Gochuico BR, Matar M, Polach K, Johannessen NM, Prosser HM, Anderson DG, Langer R, Zweier JL, Bindoff LA, Systrom D, Waxman AB, Jin RC, Chan SY. Genetic and hypoxic alterations of the microRNA-210-ISCU1/2 axis promote iron-sulfur deficiency and pulmonary hypertension. EMBO Mol Med. 2015 Jun; 7(6):695-713.
  32. Hughes AL, Yang E, Vargas SO. A pediatric soft palate mass. Pleomorphic adenoma. JAMA Otolaryngol Head Neck Surg. 2015 Apr; 141(4):391-2.
  33. Hryhorczuk AL, Kim HB, Harris MH, Vargas SO, Zurakowski D, Lee EY. Imaging findings in children with proliferative disorders following multivisceral transplantation. Pediatr Radiol. 2015 Jul; 45(8):1138-45.
  34. Tuttle KS, Vargas SO, Callahan MJ, Bae DS, Nigrovic PA. Enthesitis as a component of dactylitis in psoriatic juvenile idiopathic arthritis: histology of an established clinical entity. Pediatr Rheumatol Online J. 2015; 13:7.
  35. Gantwerker EA, Hughes AL, Silvera VM, Vargas SO, Rahbar R. Management of a large antenatally recognized foregut duplication cyst of the tongue causing respiratory distress at birth. JAMA Otolaryngol Head Neck Surg. 2014 Nov; 140(11):1065-9.
  36. Platzer B, Baker K, Vera MP, Singer K, Panduro M, Lexmond WS, Turner D, Vargas SO, Kinet JP, Maurer D, Baron RM, Blumberg RS, Fiebiger E. Dendritic cell-bound IgE functions to restrain allergic inflammation at mucosal sites. Mucosal Immunol. 2015 May; 8(3):516-32.
  37. Strazzula L, Greenlaw S, Vargas SO, Belazarian L. Child abuse masquerading as a soft tissue sarcoma. Pediatr Dermatol. 2014 Nov-Dec; 31(6):708-11.
  38. Thakrar R, Robson CD, Vargas SO, Meara JG, Rahbar R, Smith ER. Benign triton tumor: multidisciplinary approach to diagnosis and treatment. Pediatr Dev Pathol. 2014 Sep-Oct; 17(5):400-5.
  39. Bertero T, Lu Y, Annis S, Hale A, Bhat B, Saggar R, Saggar R, Wallace WD, Ross DJ, Vargas SO, Graham BB, Kumar R, Black SM, Fratz S, Fineman JR, West JD, Haley KJ, Waxman AB, Chau BN, Cottrill KA, Chan SY. Systems-level regulation of microRNA networks by miR-130/301 promotes pulmonary hypertension. J Clin Invest. 2014 Aug; 124(8):3514-28.
  40. Maron BA, Oldham WM, Chan SY, Vargas SO, Arons E, Zhang YY, Loscalzo J, Leopold JA. Upregulation of steroidogenic acute regulatory protein by hypoxia stimulates aldosterone synthesis in pulmonary artery endothelial cells to promote pulmonary vascular fibrosis. Circulation. 2014 Jul 08; 130(2):168-79.
  41. Yao LC, Testini C, Tvorogov D, Anisimov A, Vargas SO, Baluk P, Pytowski B, Claesson-Welsh L, Alitalo K, McDonald DM. Pulmonary lymphangiectasia resulting from vascular endothelial growth factor-C overexpression during a critical period. Circ Res. 2014 Feb 28; 114(5):806-22.
  42. Akhavanfard S, Vargas SO, Han M, Nitta M, Chang CB, Le LP, Fazlollahi L, Nguyen Q, Ma Y, Cosper A, Dias-Santagata D, Han JY, Bergethon K, Borger DR, Ellisen LW, Pomeroy SL, Haber DA, Iafrate AJ, Rivera MN. Inactivation of the tumor suppressor WTX in a subset of pediatric tumors. Genes Chromosomes Cancer. 2014 Jan; 53(1):67-77.
  43. Gee MS, Bittman M, Epelman M, Vargas SO, Lee EY. Magnetic resonance imaging of the pediatric kidney: benign and malignant masses. Magn Reson Imaging Clin N Am. 2013 Nov; 21(4):697-715.
  44. Simoneau T, Zandieh SO, Rao DR, Vo P, Palm KE, McCown M, Kopel LS, Dias A, Casey A, Perez-Atayde AR, Zhong Z, Graham D, Vargas SO. Impact of cilia ultrastructural examination on the diagnosis of primary ciliary dyskinesia. Pediatr Dev Pathol. 2013 Sep-Oct; 16(5):321-6.
  45. Benoit MM, Vargas SO, Bhattacharyya N, McGill TA, Robson CD, Ferraro N, Didas AE, Labow BI, Upton J, Taghinia A, Meara JG, Marcus KJ, Mack J, Rodriguez-Galindo C, Rahbar R. The presentation and management of mandibular tumors in the pediatric population. Laryngoscope. 2013 Aug; 123(8):2035-42.
  46. Wolf GK, Gómez-Laberge C, Rettig JS, Vargas SO, Smallwood CD, Prabhu SP, Vitali SH, Zurakowski D, Arnold JH. Mechanical ventilation guided by electrical impedance tomography in experimental acute lung injury. Crit Care Med. 2013 May; 41(5):1296-304.
  47. Anderson ME, Miller PE, van Nostrand K, Vargas SO. Frozen section versus gross examination for bone marrow margin assessment during sarcoma resection. Clin Orthop Relat Res. 2014 Mar; 472(3):836-41.
  48. Seng S, Kieran SM, Vargas SO, McGill TJ. Caught on camera: hairy polyp of the posterior tonsillar pillar. J Laryngol Otol. 2013 May; 127(5):528-30.
  49. Herfs M, Vargas SO, Yamamoto Y, Howitt BE, Nucci MR, Hornick JL, McKeon FD, Xian W, Crum CP. A novel blueprint for 'top down' differentiation defines the cervical squamocolumnar junction during development, reproductive life, and neoplasia. J Pathol. 2013 Feb; 229(3):460-8.
  50. Misra MV, Mullen MP, Vargas SO, Kim HB, Boyer D. Bilateral lung transplant for hereditary hemorrhagic telangiectasia in a pediatric patient. Pediatr Transplant. 2012 Dec; 16(8):E364-7.
  51. Skurnik D, Davis MR, Benedetti D, Moravec KL, Cywes-Bentley C, Roux D, Traficante DC, Walsh RL, Maira-Litràn T, Cassidy SK, Hermos CR, Martin TR, Thakkallapalli EL, Vargas SO, McAdam AJ, Lieberman TD, Kishony R, Lipuma JJ, Pier GB, Goldberg JB, Priebe GP. Targeting pan-resistant bacteria with antibodies to a broadly conserved surface polysaccharide expressed during infection. J Infect Dis. 2012 Jun; 205(11):1709-18.
  52. Ackerman KG, Vargas SO, Wilson JA, Jennings RW, Kozakewich HP, Pober BR. Congenital diaphragmatic defects: proposal for a new classification based on observations in 234 patients. Pediatr Dev Pathol. 2012 Jul-Aug; 15(4):265-74.
  53. Salgado C, Neff T, Frazier L, Vargas SO, Vanderveen D. An unusual case of congenital primitive neuroectodermal tumor with ocular metastasis. J Pediatr Hematol Oncol. 2012 Mar; 34(2):e69-71.
  54. Alaggio R, Coffin CM, Vargas SO. Soft tissue tumors of uncertain origin. Pediatr Dev Pathol. 2012; 15(1 Suppl):267-305.
  55. Laury AR, Ning G, Quick CM, Bijron J, Parast MM, Betensky RA, Vargas SO, McKeon FD, Xian W, Nucci MR, Crum CP. Fallopian tube correlates of ovarian serous borderline tumors. Am J Surg Pathol. 2011 Dec; 35(12):1759-65.
  56. Quick CM, Ning G, Bijron J, Laury A, Wei TS, Chen EY, Vargas SO, Betensky RA, McKeon FD, Xian W, Crum CP. PAX2-null secretory cell outgrowths in the oviduct and their relationship to pelvic serous cancer. Mod Pathol. 2012 Mar; 25(3):449-55.
  57. Spunt SL, Vargas SO, Coffin CM, Skapek SX, Parham DM, Darling J, Hawkins DS, Keller C. The clinical, research, and social value of autopsy after any cancer death: a perspective from the Children's Oncology Group Soft Tissue Sarcoma Committee. Cancer. 2012 Jun 15; 118(12):3002-9.
  58. Lee EY, Dorkin H, Vargas SO. Congenital pulmonary malformations in pediatric patients: review and update on etiology, classification, and imaging findings. Radiol Clin North Am. 2011 Sep; 49(5):921-48.
  59. Hryhorczuk AL, Harris MH, Vargas SO, Lee EY. Anaplastic large cell lymphoma of the esophagus in a pediatric patient. Pediatr Radiol. 2012 May; 42(5):627-31.
  60. Schwartz BE, Hofer MD, Lemieux ME, Bauer DE, Cameron MJ, West NH, Agoston ES, Reynoird N, Khochbin S, Ince TA, Christie A, Janeway KA, Vargas SO, Perez-Atayde AR, Aster JC, Sallan SE, Kung AL, Bradner JE, French CA. Differentiation of NUT midline carcinoma by epigenomic reprogramming. Cancer Res. 2011 Apr 01; 71(7):2686-96.
  61. Vargas SO. Childhood Carcinoma. Surg Pathol Clin. 2010 Sep; 3(3):689-710.
  62. Sipos A, Vargas S, Peti-Peterdi J. Direct demonstration of tubular fluid flow sensing by macula densa cells. Am J Physiol Renal Physiol. 2010 Nov; 299(5):F1087-93.
  63. Nelson BA, Lee EY, French CA, Bauer DE, Vargas SO. BRD4-NUT carcinoma of the mediastinum in a pediatric patient: multidetector computed tomography imaging findings. J Thorac Imaging. 2010 Aug; 25(3):W93-6.
  64. Aiden AP, Rivera MN, Rheinbay E, Ku M, Coffman EJ, Truong TT, Vargas SO, Lander ES, Haber DA, Bernstein BE. Wilms tumor chromatin profiles highlight stem cell properties and a renal developmental network. Cell Stem Cell. 2010 Jun 04; 6(6):591-602.
  65. Agoston AT, Liang CW, Richkind KE, Fletcher JA, Vargas SO. Trisomy 18 is a consistent cytogenetic feature in pilomatricoma. Mod Pathol. 2010 Aug; 23(8):1147-50.
  66. Rege TA, Vargas SO. Cholecystitis and cholelithiasis associated with an intramural fasciitis-like proliferation and osseous metaplasia. Pediatr Dev Pathol. 2011 Jan-Feb; 14(1):80-3.
  67. Galambos C, Levy H, Cannon CL, Vargas SO, Reid LM, Cleveland R, Lindeman R, deMello DE, Wert SE, Whitsett JA, Perez-Atayde AR, Kozakewich H. Pulmonary pathology in thyroid transcription factor-1 deficiency syndrome. Am J Respir Crit Care Med. 2010 Aug 15; 182(4):549-54.
  68. Merrell SC, Rahbar R, Alomari AI, Padua HM, Vargas SO, Neufeld EJ, Dearden JL, Mulliken JB, Greene AK. Infantile myofibroma or lymphatic malformation: differential diagnosis of neonatal cystic cervicofacial lesions. J Craniofac Surg. 2010 Mar; 21(2):422-6.
  69. Hermos CR, Vargas SO, McAdam AJ. Human metapneumovirus. Clin Lab Med. 2010 Mar; 30(1):131-48.
  70. Wang LL, Filippi RZ, Zurakowski D, Archibald T, Vargas SO, Voss SD, Shamberger RC, Davies K, Kozakewich H, Perez-Atayde AR. Effects of neoadjuvant chemotherapy on hepatoblastoma: a morphologic and immunohistochemical study. Am J Surg Pathol. 2010 Mar; 34(3):287-99.
  71. Yu DC, Pathak B, Vargas SO, Javid PJ, Hisama FM, Wilson JM, Linden BC. Congenital intra-abdominal bilateral juvenile granulosa cell tumors of the testis associated with constitutional loss of material from chromosome 4. Pediatr Dev Pathol. 2011 May-Jun; 14(3):224-7.
  72. Robson CD, Rahbar R, Vargas SO, Marcus KJ, Mack JW, Licameli GR, Grier HE. Sinonasal and laryngeal carcinoma in children: correlation of imaging characteristics with clinicopathologic and cytogenetic features. AJNR Am J Neuroradiol. 2010 Feb; 31(2):257-61.
  73. Chang MC, Vargas SO, Hornick JL, Hirsch MS, Crum CP, Nucci MR. Embryonic stem cell transcription factors and D2-40 (podoplanin) as diagnostic immunohistochemical markers in ovarian germ cell tumors. Int J Gynecol Pathol. 2009 Jul; 28(4):347-55.
  74. Fennessy BG, Vargas SO, Silvera MV, Ohlms LA, McGill TJ, Healy GB, Rahbar R. Paediatric aneurysmal bone cysts of the head and neck. J Laryngol Otol. 2009 Jun; 123(6):635-41.
  75. Florez-Vargas A, Vargas SO, Debelenko LV, Perez-Atayde AR, Archibald T, Kozakewich HP, Zurakowski D. Comparative analysis of D2-40 and LYVE-1 immunostaining in lymphatic malformations. Lymphology. 2008 Sep; 41(3):103-10.
  76. Ende L, Upton J, Richkind KE, Vargas SO. Lipoblastoma: appreciation of an expanded spectrum of disease through cytogenetic analysis. Arch Pathol Lab Med. 2008 Sep; 132(9):1442-4.
  77. Toma I, Kang JJ, Sipos A, Vargas S, Bansal E, Hanner F, Meer E, Peti-Peterdi J. Succinate receptor GPR91 provides a direct link between high glucose levels and renin release in murine and rabbit kidney. J Clin Invest. 2008 Jul; 118(7):2526-34.
  78. Rahbar R, Yoon MJ, Connolly LP, Robson CD, Vargas SO, McGill TJ, Healy GB. Lingual thyroid in children: a rare clinical entity. Laryngoscope. 2008 Jul; 118(7):1174-9.
  79. Vargas SO, Reyes-Múgica M. Relaunching the "Current Practice in Pediatric Pathology" section. Pediatr Dev Pathol. 2008 Jul-Aug; 11(4):253.
  80. Gutweiler JR, Labelle J, Suh MY, Misra MV, Ahmed M, Lee EY, Vargas SO, Kim HB, Weldon CB. A familial case of pleuropulmonary blastoma. Eur J Pediatr Surg. 2008 Jun; 18(3):192-4.
  81. Ikwueke I, Bandara S, Fishman SJ, Vargas SO. Congenital dermal sinus tract in the lateral buttock: unusual presentation of a typically midline lesion. J Pediatr Surg. 2008 Jun; 43(6):1200-2.
  82. Garrett LA, Vargas SO, Drapkin R, Laufer MR. Does the fimbria have an embryologic origin distinct from that of the rest of the fallopian tube? Fertil Steril. 2008 Nov; 90(5):2008.e5-8.
  83. Gleason BC, Vargas SO. Immunosuppression-related fibroproliferative polyps: a substantial subset of acquired pediatric mucocutaneous polyps. Pediatr Dev Pathol. 2008 Jan-Feb; 11(1):30-4.
  84. Vargas SO, Grudzien C, Tanasijevic MJ. Postmortem cardiac troponin-I levels predict intramyocardial damage at autopsy. J Thromb Thrombolysis. 2008 Oct; 26(2):132-7.
  85. Lee EY, Vargas SO, Sawicki GS, Boyer D, Grant FD, Voss SD. Mucoepidermoid carcinoma of bronchus in a pediatric patient: (18)F-FDG PET findings. Pediatr Radiol. 2007 Dec; 37(12):1278-82.
  86. Rodriguez KH, Vargas S, Robson C, Perez-Atayde A, Shamberger R, McGill TJ, Healy GB, Rahbar R. Pleomorphic adenoma of the parotid gland in children. Int J Pediatr Otorhinolaryngol. 2007 Nov; 71(11):1717-23.
  87. Vargas SO, Perez-Atayde AR, Padwa BL, Springer KM. Immunosuppression-related fibroproliferative polyps of the tongue. Pediatr Dev Pathol. 2007 Jul-Aug; 10(4):256-65.
  88. Lowry CM, Marty FM, Vargas SO, Lee JT, Fiumara K, Deykin A, Baden LR. Safety of aerosolized liposomal versus deoxycholate amphotericin B formulations for prevention of invasive fungal infections following lung transplantation: a retrospective study. Transpl Infect Dis. 2007 Jun; 9(2):121-5.
  89. Rahbar R, Brown LF, Folkman J, McGill TJ, Healy GB, Liu G, Vargas SO. Role of vascular endothelial growth factor A in children with acquired airway stenosis. Ann Otol Rhinol Laryngol. 2007 Jun; 116(6):430-5.
  90. Rivera MN, Kim WJ, Wells J, Driscoll DR, Brannigan BW, Han M, Kim JC, Feinberg AP, Gerald WL, Vargas SO, Chin L, Iafrate AJ, Bell DW, Haber DA. An X chromosome gene, WTX, is commonly inactivated in Wilms tumor. Science. 2007 Feb 02; 315(5812):642-5.
  91. Vargas SO. USCAP specialty conference, case 1: Childhood asymmetric labium majus enlargement. Pediatr Devel Pathol. 2007; in press.
  92. Vargas SO, Legallo RD, Pascacio JM, Moore J, Qualman SJ. Primary pediatric intrathoracic primitive sarcomas: critical reappraisal of the spectrum of pleuropulmonary blastoma based on review of 63 patients. Modern Pathol. 2007; 20:293.
  93. Riedlinger WF, Vargas SO, Jennings RW, Estroff JA, Barnewolt CE, Lillehei CW, Wilson JM, Colin AA, Reid LM, Kozakewich HP. Bronchial atresia is common to extralobar sequestration, intralobar sequestration, congenital cystic adenomatoid malformation, and lobar emphysema. Pediatr Dev Pathol. 2006 Sep-Oct; 9(5):361-73.
  94. Boyer D, Vargas SO, Slattery D, Rivera-Sanchez YM, Colin AA. Churg-Strauss syndrome in children: a clinical and pathologic review. Pediatrics. 2006 Sep; 118(3):e914-20.
  95. Vargas SO, Korpershoek E, Kozakewich HP, de Krijger RR, Fletcher JA, Perez-Atayde AR. Cytogenetic and p53 profiles in congenital cystic adenomatoid malformation: insights into its relationship with pleuropulmonary blastoma. Pediatr Dev Pathol. 2006 May-Jun; 9(3):190-5.
  96. Rahbar R, Grimmer JF, Vargas SO, Robson CD, Mack JW, Perez-Atayde AR, Marcus KJ, Grier HE, Healy GB, McGill TJ. Mucoepidermoid carcinoma of the parotid gland in children: A 10-year experience. Arch Otolaryngol Head Neck Surg. 2006 Apr; 132(4):375-80.
  97. Wang L, Lilic N, Vargas SO, Archibald T, Shamberger R, Kozakewich H, Perez-Atayde AR . Effects of preoperative chemotherapy on hepatoblastoma: a morphological and immunohistochemical study. Modern Pathol. 2006; 19(2):327.
  98. Vargas SO, Perez-Atayde AR, French CA. Histopathologic spectrum of tumors containing BRD4-NUT fusion or variant rearrangements involving one of these two genes. Modern Pathol. 2006; 19(2):327.
  99. Kurek KC, Perez-Atayde AR, Kozakewich HPW, Richkind KE, Degar BA, Vargas SO. Epstein-Barr virus-associated smooth muscle tumors: observations expanding the clinical and cytogenetic spectrum of disease. Modern Pathol. 2006; 19(Supp 3):154-155.
  100. VanBeek CA, Kozakewich HPW, Perez-Atayde AR, Laufer MR, Vargas SO . Labium minus hypertrophy: etiologic considerations based on clinicopathologic investigation. Modern Pathol. 2006; 19(2):327.
  101. Arredouani MS, Palecanda A, Koziel H, Huang YC, Imrich A, Sulahian TH, Ning YY, Yang Z, Pikkarainen T, Sankala M, Vargas SO, Takeya M, Tryggvason K, Kobzik L. MARCO is the major binding receptor for unopsonized particles and bacteria on human alveolar macrophages. J Immunol. 2005 Nov 01; 175(9):6058-64.
  102. Riedlinger WF, Kozakewich HP, Vargas SO. Myogenic markers in the evaluation of embryonal botryoid rhabdomyosarcoma of the female genital tract. Pediatr Dev Pathol. 2005 Jul-Aug; 8(4):427-34.
  103. Brock JE, Perez-Atayde AR, Kozakewich HP, Richkind KE, Fletcher JA, Vargas SO. Cytogenetic aberrations in perineurioma: variation with subtype. Am J Surg Pathol. 2005 Sep; 29(9):1164-9.
  104. Vargas SO, Kozakewich HP, Boyd TK, Ecklund K, Fishman SJ, Laufer MR, Perez-Atayde AR. Childhood asymmetric labium majus enlargement: mimicking a neoplasm. Am J Surg Pathol. 2005 Aug; 29(8):1007-16.
  105. VanBeek CA, Peters CA, Vargas SO. Ectopic prostate tissue within the processus vaginalis: insights into prostate embryogenesis. Pediatr Dev Pathol. 2005 May-Jun; 8(3):379-85.
  106. Riedlinger WF, Kozakewich HP, Vargas SO. Myogenic markers in the evaluation of embryonal botryoid rhabdomyosarcoma of the female genital tract. Pediatr Dev Pathol. 2005 May-Jun; 8(3):355-61.
  107. Ackerman KG, Herron BJ, Vargas SO, Huang H, Tevosian SG, Kochilas L, Rao C, Pober BR, Babiuk RP, Epstein JA, Greer JJ, Beier DR. Fog2 is required for normal diaphragm and lung development in mice and humans. PLoS Genet. 2005 Jul; 1(1):58-65.
  108. Rahbar R, Vargas SO, Folkman J, McGill TJ, Healy GB, Tan X, Brown LF. Role of vascular endothelial growth factor-A in recurrent respiratory papillomatosis. Ann Otol Rhinol Laryngol. 2005 Apr; 114(4):289-95.
  109. Ehsan A, Singh H, Vargas SO, Sachweh J, Jonas RA. Neoaortic aneurysm after stage I Norwood reconstruction. Ann Thorac Surg. 2005 Mar; 79(3):e23-5.
  110. Argani P, Laé M, Hutchinson B, Reuter VE, Collins MH, Perentesis J, Tomaszewski JE, Brooks JS, Acs G, Bridge JA, Vargas SO, Davis IJ, Fisher DE, Ladanyi M. Renal carcinomas with the t(6;11)(p21;q12): clinicopathologic features and demonstration of the specific alpha-TFEB gene fusion by immunohistochemistry, RT-PCR, and DNA PCR. Am J Surg Pathol. 2005 Feb; 29(2):230-40.
  111. Bry L, Vargas SO, McAdam AJ. The role of Burkholderia cepacia complex infections in patients with cystic fibrosis. Check Sample Series. ASCP Press. 2005.
  112. Iafrate AJ, Vargas SO . Phenotype-genotype correlations in chromosome 4q deletion with involvement of KIT and PDGFRA genes. Modern Pathol. 2005; 18(Supp 1):8A.
  113. Brock JE, Butte MJ, Fishman SJ, Vargas SO. Large lymphatic malformation associated with CD4 lymphopenia without immunodeficiency: a sink for CD4+/CD45RA+ naive T cells. Modern Pathol. 2005; 18:310.
  114. Rahbar R, Litrovnik BG, Vargas SO, Robson CD, Nuss RC, Irons MB, McGill TJ, Healy GB. The biology and management of laryngeal neurofibroma. Arch Otolaryngol Head Neck Surg. 2004 Dec; 130(12):1400-6.
  115. French CA, Kutok JL, Faquin WC, Toretsky JA, Antonescu CR, Griffin CA, Nose V, Vargas SO, Moschovi M, Tzortzatou-Stathopoulou F, Miyoshi I, Perez-Atayde AR, Aster JC, Fletcher JA. Midline carcinoma of children and young adults with NUT rearrangement. J Clin Oncol. 2004 Oct 15; 22(20):4135-9.
  116. Vargas SO, Kozakewich HP, Perez-Atayde AR, McAdam AJ. Pathology of human metapneumovirus infection: insights into the pathogenesis of a newly identified respiratory virus. Pediatr Dev Pathol. 2004 Sep-Oct; 7(5):478-86; discussion 421.
  117. Barry M, Vargas SO . The pathology of umbilical epithelial remnants in children. Modern Pathol. 2004; 17:767.
  118. Prasad V, Perez-Atayde AR, Vargas SO, Nose V, Laufer M, Kozakewich HPW . Increased incidence of vaginal adenosis in children with selected uterovaginal anomalies. Modern Pathol. 2004; 17:272.
  119. Rahbar R, Vargas SO, Miyamoto CR, Perez-Atayde AR, French CA, Robson CD, Licameli GR, Fletcher JA, Marcus KC, Grier HE, McGill TJ, Healy GB. The role of chromosomal translocation (15;19) in the carcinoma of the upper aerodigestive tract in children. Otolaryngol Head Neck Surg. 2003 Dec; 129(6):698-704.
  120. Sedeek KA, Takeuchi M, Suchodolski K, Vargas SO, Shimaoka M, Schnitzer JJ, Kacmarek RM. Open-lung protective ventilation with pressure control ventilation, high-frequency oscillation, and intratracheal pulmonary ventilation results in similar gas exchange, hemodynamics, and lung mechanics. Anesthesiology. 2003 Nov; 99(5):1102-11.
  121. Drapkin RI, Genest DR, Holmes LB, Huang T, Vargas SO. Unilateral transverse arm defect with subterminal digital nubbins. Pediatr Dev Pathol. 2003 Jul-Aug; 6(4):348-54.
  122. Adey GS, Vargas SO, Retik AB, Borer JG, Mandell J, Hendren WH, Lebowitz RL, Bauer SB. Fibroepithelial polyps causing ureteropelvic junction obstruction in children. J Urol. 2003 May; 169(5):1834-6.
  123. Davis IJ, Hsi BL, Arroyo JD, Vargas SO, Yeh YA, Motyckova G, Valencia P, Perez-Atayde AR, Argani P, Ladanyi M, Fletcher JA, Fisher DE. Cloning of an Alpha-TFEB fusion in renal tumors harboring the t(6;11)(p21;q13) chromosome translocation. Proc Natl Acad Sci U S A. 2003 May 13; 100(10):6051-6.
  124. Duran-Mendicuti A, Costello P, Vargas SO. Primary synovial sarcoma of the chest: radiographic and clinicopathologic correlation. J Thorac Imaging. 2003 Apr; 18(2):87-93.
  125. Colwell AS, Mentzer SJ, Vargas SO, Orgill DP. The role of muscle flaps in pulmonary aspergillosis. Plast Reconstr Surg. 2003 Mar; 111(3):1147-50.
  126. Coleman FT, Mueschenborn S, Meluleni G, Ray C, Carey VJ, Vargas SO, Cannon CL, Ausubel FM, Pier GB. Hypersusceptibility of cystic fibrosis mice to chronic Pseudomonas aeruginosa oropharyngeal colonization and lung infection. Proc Natl Acad Sci U S A. 2003 Feb 18; 100(4):1949-54.
  127. Ayala C, Healy GB, Robson CD, Vargas SO. Psammomatous calcification in association with a benign thyroglossal duct cyst. Arch Otolaryngol Head Neck Surg. 2003 Feb; 129(2):241-3.
  128. Turvey SE, Vargas SO, Phipatanakul W. Churg-Strauss syndrome in a 7-year-old receiving montelukast and inhaled corticosteroids. Ann Allergy Asthma Immunol. 2003 Feb; 90(2):274.
  129. Suchodolski K, El Masry A, Vargas SO, Kacmarek RM . 1361, L-SELECTIN inhibitor, fucoidin, minimizes ventilator induced lung injury. Am J Respir Crit Care Med. 2003.
  130. Galambos C, Levy H, Lindeman R, Cannon C, deMello DE, Vargas SO, Perez-Atayde AR, Kozakewich H . Pulmonary pathology in thyroid transcription factor-1 (TTF-1) deficiency syndrome. Modern Pathol. 2003; 16:3P.
  131. Galambos C, Vargas SO, Arnold J, Reid L, Perez-Atayde AR, Kozakewich H . Congenital alveolar dysplasia. Modern Pathol. 2003; 16:3P.
  132. Bornstein-Quevedo L, Lehmann L, Vargas SO, Kozakewich HPW, Perez-Atayde AR. Alk+ anaplastic large cell lymphoma (ALCL) in children: a clinicopathologic study. Modern Pathol. 2003; 16:1P.
  133. Colwell AS, D'Cunha J, Vargas SO, Parker B, Dal Cin P, Maddaus MA. Synovial sarcoma of the pleura: a clinical and pathologic study of three cases. J Thorac Cardiovasc Surg. 2002 Oct; 124(4):828-32.
  134. Essary LR, Vargas SO, Fletcher CD. Primary pleuropulmonary synovial sarcoma: reappraisal of a recently described anatomic subset. Cancer. 2002 Jan 15; 94(2):459-69.
  135. Kessler JL, Miyamoto RC, Vargas SO, Rahbar R. Neonatal nasopharyngeal teratoma presenting with airway obstruction. 2002.
  136. Vargas SO, Wessel DL, Reid LM, Kozakewich HPW . Misalignment of pulmonary veins: report of 21 cases with emphasis on associated congenital anomalies. Modern Pathol. 2002; 15:7P.
  137. Vargas SO, Nosé V, Fletcher JA, Perez-Atayde AR. Gains of chromosome 8 in pleuropulmonary blastoma of childhood (reply) [letter]. Pediatr Dev Pathol. 2002; 5:222.
  138. Lichtman AH, Vargas SO. Pathology lab manual. Co-authored revision of manual for IN714.0: Pathology AY03, Harvard Medical School. 2002.
  139. Suchodolski K, Keck T, Vargas S, Kacmarek RM . Matrix metalloproteinase (MMP) inhibitor, batimastat (BB-94), minimizes ventilator induced lung injury. Am J Respir Crit Care Med. 2002.
  140. Ditelberg JS, Vargas SO. Juvenile xanthogranuloma: diagnostic difficulties presented by the “giant” variant. Modern Pathol. 2002; 15:2P.
  141. French CA, Miyoshi I, Aster JC, Kubonishi I, Kroll TG, Dal Cin P, Vargas SO, Perez-Atayde AR, Fletcher JA. BRD4 bromodomain gene rearrangement in aggressive carcinoma with translocation t(15;19). Am J Pathol. 2001 Dec; 159(6):1987-92.
  142. Vargas SO. Fibrous umbilical polyp: a distinct fasciitis-like proliferation of early childhood with a marked male predominance. Am J Surg Pathol. 2001 Nov; 25(11):1438-42.
  143. Vargas SO, French CA, Faul PN, Fletcher JA, Davis IJ, Dal Cin P, Perez-Atayde AR. Upper respiratory tract carcinoma with chromosomal translocation 15;19: evidence for a distinct disease entity of young patients with a rapidly fatal course. Cancer. 2001 Sep 01; 92(5):1195-203.
  144. Vargas SO, Nosé V, Fletcher JA, Perez-Atayde AR. Gains of chromosome 8 are confined to mesenchymal components in pleuropulmonary blastoma. Pediatr Dev Pathol. 2001 Sep-Oct; 4(5):434-45.
  145. Vargas SO, Perez-Atayde AR, González-Crussi F, Kozakewich HP. Giant cell angioblastoma: three additional occurrences of a distinct pathologic entity. Am J Surg Pathol. 2001 Feb; 25(2):185-96.
  146. Vargas SO, Fletcher JA, Kozakewich HPW, Perez-Atayde AR. . Cemento-ossifying fibroma shares chromosome 12p rearrangements with other benign bone lesions. Modern Pathol. 2001; 14:19A.
  147. Ditelberg JS, Bartlett R, McKee PH, Vargas SO. Giant juvenile xanthogranuloma: Diagnostic difficulty presented by a rare variant of a rare childhood lesion. Journal of Cutaneous Pathology. 2001; 28:549.
  148. Vargas SO, Gula E, Stamper D, Patel N, Fujimoto JG, Brezinski ME. Optical “biopsy” of the pediatric gastrointestinal tract using optical coherence tomography. Pediatr Dev Pathol. 2001; 14:7P.
  149. Grotas JA, Diamond DA, Vargas SO. Granular cell tumor of the penis in a 5-year-old boy. Urology. 2000 Jul 01; 56(1):154.
  150. Vargas SO, Jiroutek M, D'Amico AV, Renshaw AA. Distribution of carcinoma in radical prostatectomy specimens in the era of serum prostate-specific antigen testing. Implications for delivery of localized therapy. Am J Clin Pathol. 1999 Sep; 112(3):373-6.
  151. Vargas SO, Hasegawa SL, Dorfman DM. Hematogones as an internal control in flow cytometric analysis of suspected acute lymphoblastic leukemia. Pediatr Dev Pathol. 1999 Jul-Aug; 2(4):371-6.
  152. Vargas SO, Sampson BA, Schoen FJ. Pathologic detection of early myocardial infarction: a critical review of the evolution and usefulness of modern techniques. Mod Pathol. 1999 Jun; 12(6):635-45.
  153. Vargas SO, Cannon ME, Benjamin RJ, Longtine JA. Transfusion with blood from a donor with chronic myelogenous leukemia: persistence of the bcr/abl translocation in the recipient. Transfusion. 1999 Apr; 39(4):387-91.
  154. D'Amico AV, Davis A, Vargas SO, Renshaw AA, Jiroutek M, Richie JP. Defining the implant treatment volume for patients with low risk prostate cancer: does the anterior base need to be treated? Int J Radiat Oncol Biol Phys. 1999 Feb 01; 43(3):587-90.
  155. Vargas SO, Jiroutek M, Welch WR, Nucci MR, D'Amico AV, Renshaw AA. Perineural invasion in prostate needle biopsy specimens. Correlation with extraprostatic extension at resection. Am J Clin Pathol. 1999 Feb; 111(2):223-8.
  156. Vargas SO, Grudzien C, Tanasijevic MJ. Cardiac troponin-I in postmortem serum specimens. Modern Pathol. 1999; 12:9A.
  157. Vargas SO, Leslie KO, Vacek PM, Socinski MA, Weaver DL. Estrogen-receptor-related protein p29 in primary nonsmall cell lung carcinoma: pathologic and prognostic correlations. Cancer. 1998 Apr 15; 82(8):1495-500.
  158. Vargas SO, Horensky D, Onderdonk AB. Evaluation of a new enzyme immunoassay for Clostridium difficile toxin A. J Clin Pathol. 1997 Dec; 50(12):996-1000.
  159. Vargas SO. Bacterial contamination in blood components: new awareness of an old problem. Infect Dis Clin Pract. 1997; 6:528-531.
  160. Lopez-Jimenez F, Goldman L, Vargas SO, Thomas EJ, Johnson PA, Cook EF, Lee TH, Sacks DB. Cardiac troponin T is a prognostic indicator for cardiac complications after noncardiac surgery: six month follow-up data. Clin Chem. 1997; 43:S126.
  161. Vargas SO, McAdam AJ, Weinberg DS. Analysis of microscopic technique to determine sources of inaccuracy in peripheral blood smear manual differential counts. Am J Clin Pathol. 1997; 108-345.
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