EDUCATION

Undergraduate Degree

  • Tufts University , Medford , MA

Medical School

  • University of Tennessee College of Medicine , Memphis , TN

Internship

Pediatrics
  • Boston Combined Residency Program (BCRP) , Boston , MA

Residency

Pediatric Hematology -Oncology
  • Boston Children's Hospital/ Dana-Farber Cancer Institute , Boston , MA

Fellowship

Pediatric Hematology -Oncology
  • Boston Children's Hospital/ Dana-Farber Cancer Institute , Boston , MA

Fellowship

Post -Doctoral Research
  • Beth Israel Deaconess Medical Center , Boston , MA

CERTIFICATIONS

  • American Board of Pediatrics, Pediatric Hematology and Oncology

PUBLICATIONS

Publications powered by Harvard Catalyst Profiles

  1. Iacobas I, Phung TL, Adams DM, Trenor CC, Blei F, Fishman DS, Hammill A, Masand PM, Fishman SJ. Guidance Document for Hepatic Hemangioma (Infantile and Congenital) Evaluation and Monitoring. J Pediatr. 2018 Dec; 203:294-300.e2. View abstract
  2. Taghinia AH, Upton J, Trenor CC, Alomari AI, Lillis AP, Shaikh R, Burrows PE, Fishman SJ. Lymphaticovenous bypass of the thoracic duct for the treatment of chylous leak in central conducting lymphatic anomalies. J Pediatr Surg. 2018 Sep 09. View abstract
  3. Reis J, Alomari AI, Trenor CC, Adams DM, Fishman SJ, Spencer SA, Shaikh R, Lillis AP, Surnedi MK, Chaudry G. Pulmonary thromboembolic events in patients with congenital lipomatous overgrowth, vascular malformations, epidermal nevi, and spinal/skeletal abnormalities and Klippel-Trénaunay syndrome. J Vasc Surg Venous Lymphat Disord. 2018 07; 6(4):511-516. View abstract
  4. Mo AZ, Trenor CC, Hedequist DJ. Sirolimus Therapy as Perioperative Treatment of Gorham-Stout Disease in the Thoracic Spine: A Case Report. JBJS Case Connect. 2018 Jul-Sep; 8(3):e70. View abstract
  5. Nair AG, Oladunjoye OO, Trenor CC, LaRonde M, van den Bosch SJ, Sleeper LA, VanderPluym C, Emani SM, Kheir JN. An anticoagulation protocol for use after congenital cardiac surgery. J Thorac Cardiovasc Surg. 2018 Jul; 156(1):343-352.e4. View abstract
  6. Oladunjoye OO, Sleeper LA, Nair AG, Trenor CC, VanderPluym C, Kheir JN, Emani SM. Partial thromboplastin time is more predictive of bleeding than anti-Xa levels in heparinized pediatric patients after cardiac surgery. J Thorac Cardiovasc Surg. 2018 Jul; 156(1):332-340.e1. View abstract
  7. Bernson-Leung ME, Boyd TK, Meserve EE, Danehy AR, Kapur K, Trenor CC, Lehman LL, Rivkin MJ. Placental Pathology in Neonatal Stroke: A Retrospective Case-Control Study. J Pediatr. 2018 Apr; 195:39-47.e5. View abstract
  8. Hunt R, Hoffman CM, Emani S, Trenor CC, Emani SM, Faraoni D, Kimchi-Sarfaty C, Ibla JC. Elevated preoperative von Willebrand factor is associated with perioperative thrombosis in infants and neonates with congenital heart disease. J Thromb Haemost. 2017 12; 15(12):2306-2316. View abstract
  9. Yang E, Storey A, Olson HE, Soul J, Estroff JA, Trenor CC, Cooper BK, Smith ER, Orbach DB. Imaging features and prognostic factors in fetal and postnatal torcular dural sinus malformations, part I: review of experience at Boston Children's Hospital. J Neurointerv Surg. 2018 May; 10(5):467-470. View abstract
  10. Yang E, Storey A, Olson HE, Soul J, Estroff JA, Trenor CC, Cooper BK, Smith ER, Orbach DB. Imaging features and prognostic factors in fetal and postnatal torcular dural sinus malformations, part II: synthesis of the literature and patient management. J Neurointerv Surg. 2018 May; 10(5):471-475. View abstract
  11. Strychowsky JE, Rahbar R, O'Hare MJ, Irace AL, Padua H, Trenor CC. Sirolimus as treatment for 19 patients with refractory cervicofacial lymphatic malformation. Laryngoscope. 2018 01; 128(1):269-276. View abstract
  12. Adams DM, Brandão LR, Peterman CM, Gupta A, Patel M, Fishman S, Trenor CC. Vascular anomaly cases for the pediatric hematologist oncologists-An interdisciplinary review. Pediatr Blood Cancer. 2018 Jan; 65(1). View abstract
  13. Lehman LL, Danehy AR, Trenor CC, Calahan CF, Bernson-Leung ME, Robertson RL, Rivkin MJ. Transient Focal Neurologic Symptoms Correspond to Regional Cerebral Hypoperfusion by MRI: A Stroke Mimic in Children. AJNR Am J Neuroradiol. 2017 Nov; 38(11):2199-2202. View abstract
  14. Lehman LL, Beaute J, Kapur K, Danehy AR, Bernson-Leung ME, Malkin H, Rivkin MJ, Trenor CC. Workup for Perinatal Stroke Does Not Predict Recurrence. Stroke. 2017 08; 48(8):2078-2083. View abstract
  15. Emani S, Zurakowski D, Mulone M, DiNardo JA, Trenor CC, Emani SM. Platelet testing to guide aspirin dose adjustment in pediatric patients after cardiac surgery. J Thorac Cardiovasc Surg. 2017 Nov; 154(5):1723-1730. View abstract
  16. Peterman CM, Fevurly RD, Alomari AI, Trenor CC, Adams DM, Vadeboncoeur S, Liang MG, Greene AK, Mulliken JB, Fishman SJ. Sonographic screening for Wilms tumor in children with CLOVES syndrome. Pediatr Blood Cancer. 2017 Dec; 64(12). View abstract
  17. Com G, Awad S, Trenor CC. Delayed Appearance of Cutaneous Lesions of Cutaneovisceral Angiomatosis (CAT) Leading to Misdiagnosis of Immune Thrombocytopenia. J Pediatr Hematol Oncol. 2017 05; 39(4):e236-e239. View abstract
  18. Le Cras TD, Mobberley-Schuman PS, Broering M, Fei L, Trenor CC, Adams DM. Angiopoietins as serum biomarkers for lymphatic anomalies. Angiogenesis. 2017 Feb; 20(1):163-173. View abstract
  19. Trenor CC. Medical management of vascular anomalies. Semin Cutan Med Surg. 2016 Sep; 35(3):177-81. View abstract
  20. Kelly DP, Bairdain S, Zurakowski D, Dodson B, Harney KM, Jennings RW, Trenor CC. Quality improvement program reduces venous thromboembolism in infants and children with long-gap esophageal atresia (LGEA). Pediatr Surg Int. 2016 Jul; 32(7):691-6. View abstract
  21. Goyal P, Alomari AI, Kozakewich HP, Trenor CC, Perez-Atayde AR, Fishman SJ, Greene AK, Shaikh R, Chaudry G. Imaging features of kaposiform lymphangiomatosis. Pediatr Radiol. 2016 Aug; 46(9):1282-90. View abstract
  22. Adams DM, Trenor CC, Hammill AM, Vinks AA, Patel MN, Chaudry G, Wentzel MS, Mobberley-Schuman PS, Campbell LM, Brookbank C, Gupta A, Chute C, Eile J, McKenna J, Merrow AC, Fei L, Hornung L, Seid M, Dasgupta AR, Dickie BH, Elluru RG, Lucky AW, Weiss B, Azizkhan RG. Efficacy and Safety of Sirolimus in the Treatment of Complicated Vascular Anomalies. Pediatrics. 2016 Feb; 137(2):e20153257. View abstract
  23. Adams DM, Hammill AM, Mobberley-Schuman PS, Trenor CC. Comment on: Steroid-resistant kaposiform hemangioendothelioma: A retrospective study of 37 patients treated with vincristine and long-term follow-up. Pediatr Blood Cancer. 2015 Nov; 62(11):2056. View abstract
  24. Rankin H, Zwicker K, Trenor CC. Caution is recommended prior to sildenafil use in vascular anomalies. Pediatr Blood Cancer. 2015 Nov; 62(11):2015-7. View abstract
  25. Trenor CC, Fisher JG, Khan FA, Sparks EA, Duzan J, Harney K, Dillon B, Menard M, Modi BP. Paget-Schroetter syndrome in 21 children: outcomes after multidisciplinary care. J Pediatr. 2015 Jun; 166(6):1493-7.e1. View abstract
  26. Luks VL, Kamitaki N, Vivero MP, Uller W, Rab R, Bovée JV, Rialon KL, Guevara CJ, Alomari AI, Greene AK, Fishman SJ, Kozakewich HP, Maclellan RA, Mulliken JB, Rahbar R, Spencer SA, Trenor CC, Upton J, Zurakowski D, Perkins JA, Kirsh A, Bennett JT, Dobyns WB, Kurek KC, Warman ML, McCarroll SA, Murillo R. Lymphatic and other vascular malformative/overgrowth disorders are caused by somatic mutations in PIK3CA. J Pediatr. 2015 Apr; 166(4):1048-54.e1-5. View abstract
  27. Obeng EA, Harney KM, Moniz T, Arnold A, Neufeld EJ, Trenor CC. Pediatric heparin-induced thrombocytopenia: prevalence, thrombotic risk, and application of the 4Ts scoring system. J Pediatr. 2015 Jan; 166(1):144-50. View abstract
  28. Uller W, Kozakewich HP, Trenor CC, O'Hare M, Alomari AI. Cutaneovisceral angiomatosis with thrombocytopenia without cutaneous involvement. J Pediatr. 2014 Oct; 165(4):876-876.e1. View abstract
  29. Trenor CC, Chaudry G. Complex lymphatic anomalies. Semin Pediatr Surg. 2014 Aug; 23(4):186-90. View abstract
  30. Orbach D, Storey A, Morash D, Estroff J, Smith E, Trenor C, Olson H. E-066 pathogenesis of dural sinus malformations as demonstrated by fetal imaging: a decision-making crucible for parents and clinicians. J Neurointerv Surg. 2014 Jul; 6 Suppl 1:A69-70. View abstract
  31. Zitomersky NL, Trenor CC. Authors' response. J Pediatr Gastroenterol Nutr. 2014 Jun; 58(6):e58. View abstract
  32. Bairdain S, Kelly DP, Tan C, Dodson B, Zurakowski D, Zurakowksi D, Jennings RW, Trenor CC. High incidence of catheter-associated venous thromboembolic events in patients with long gap esophageal atresia treated with the Foker process. J Pediatr Surg. 2014 Feb; 49(2):370-3. View abstract
  33. Alomari AI, Spencer SA, Arnold RW, Chaudry G, Kasser JR, Burrows PE, Govender P, Padua HM, Dillon B, Upton J, Taghinia AH, Fishman SJ, Mulliken JB, Fevurly RD, Greene AK, Landrigan-Ossar M, Paltiel HJ, Trenor CC, Kozakewich HP. Fibro-adipose vascular anomaly: clinical-radiologic-pathologic features of a newly delineated disorder of the extremity. J Pediatr Orthop. 2014 Jan; 34(1):109-17. View abstract
  34. Croteau SE, Kozakewich HP, Perez-Atayde AR, Fishman SJ, Alomari AI, Chaudry G, Mulliken JB, Trenor CC. Kaposiform lymphangiomatosis: a distinct aggressive lymphatic anomaly. J Pediatr. 2014 Feb; 164(2):383-8. View abstract
  35. Emani S, Zurakowski D, Baird CW, Pigula FA, Trenor C, Emani SM. Hypercoagulability panel testing predicts thrombosis in neonates undergoing cardiac surgery. Am J Hematol. 2014 Feb; 89(2):151-5. View abstract
  36. Zitomersky NL, Levine AE, Atkinson BJ, Harney KM, Verhave M, Bousvaros A, Lightdale JR, Trenor CC. Risk factors, morbidity, and treatment of thrombosis in children and young adults with active inflammatory bowel disease. J Pediatr Gastroenterol Nutr. 2013 Sep; 57(3):343-7. View abstract
  37. Drolet BA, Trenor CC, Brandão LR, Chiu YE, Chun RH, Dasgupta R, Garzon MC, Hammill AM, Johnson CM, Tlougan B, Blei F, David M, Elluru R, Frieden IJ, Friedlander SF, Iacobas I, Jensen JN, King DM, Lee MT, Nelson S, Patel M, Pope E, Powell J, Seefeldt M, Siegel DH, Kelly M, Adams DM. Consensus-derived practice standards plan for complicated Kaposiform hemangioendothelioma. J Pediatr. 2013 Jul; 163(1):285-91. View abstract
  38. Emani S, Zurakowski D, Baird CW, Pigula FA, Trenor C, Emani SM. Hypercoagulability markers predict thrombosis in single ventricle neonates undergoing cardiac surgery. Ann Thorac Surg. 2013 Aug; 96(2):651-6. View abstract
  39. Emani S, Sista R, Loyola H, Trenor CC, Pamula VK, Emani SM. Novel microfluidic platform for automated lab-on-chip testing of hypercoagulability panel. Blood Coagul Fibrinolysis. 2012 Dec; 23(8):760-8. View abstract
  40. Barranco-Pons R, Burrows PE, Landrigan-Ossar M, Trenor CC, Alomari AI. Gross hemoglobinuria and oliguria are common transient complications of sclerotherapy for venous malformations: review of 475 procedures. AJR Am J Roentgenol. 2012 Sep; 199(3):691-4. View abstract
  41. Croteau SE, Liang MG, Kozakewich HP, Alomari AI, Fishman SJ, Mulliken JB, Trenor CC. Kaposiform hemangioendothelioma: atypical features and risks of Kasabach-Merritt phenomenon in 107 referrals. J Pediatr. 2013 Jan; 162(1):142-7. View abstract
  42. Kurek KC, Howard E, Tennant LB, Upton J, Alomari AI, Burrows PE, Chalache K, Harris DJ, Trenor CC, Eng C, Fishman SJ, Mulliken JB, Perez-Atayde AR, Kozakewich HP. PTEN hamartoma of soft tissue: a distinctive lesion in PTEN syndromes. Am J Surg Pathol. 2012 May; 36(5):671-87. View abstract
  43. Trenor CC. Sirolimus for refractory vascular anomalies. Pediatr Blood Cancer. 2011 Dec 01; 57(6):904-5. View abstract
  44. Zwicker JI, Trenor CC, Furie BC, Furie B. Tissue factor-bearing microparticles and thrombus formation. Arterioscler Thromb Vasc Biol. 2011 Apr; 31(4):728-33. View abstract
  45. Trenor CC, Chung RJ, Michelson AD, Neufeld EJ, Gordon CM, Laufer MR, Emans SJ. Hormonal contraception and thrombotic risk: a multidisciplinary approach. Pediatrics. 2011 Feb; 127(2):347-57. View abstract
  46. Zitomersky NL, Verhave M, Trenor CC. Thrombosis and inflammatory bowel disease: a call for improved awareness and prevention. Inflamm Bowel Dis. 2011 Jan; 17(1):458-70. View abstract
  47. Trenor CC. Thrombosis and thrombophilia: principles for pediatric patients. Blood Coagul Fibrinolysis. 2010 Sep; 21 Suppl 1:S11-5. View abstract
  48. Trenor CC, Michelson AD. Thrombophilia and pediatric stroke. Circulation. 2010 Apr 27; 121(16):1795-7. View abstract
  49. Kentsis A, Bradwin G, Miller DT, Trenor CC. Venous thrombosis associated with gene deletion of tissue factor pathway inhibitor. Am J Hematol. 2009 Nov; 84(11):775-6. View abstract
  50. Shin AY, Almond CS, Mannix RC, Duncan CN, Son MB, McLauchlan HM, Kanaan UB, Litzow JM, Riney PS, Trenor CC, Fortescue EB, Vinci RJ, Greenes DS. The Boston Marathon Study: a novel approach to research during residency. Pediatrics. 2006 May; 117(5):1818-22. View abstract
  51. Lim JE, Jin O, Bennett C, Morgan K, Wang F, Trenor CC, Fleming MD, Andrews NC. A mutation in Sec15l1 causes anemia in hemoglobin deficit (hbd) mice. Nat Genet. 2005 Nov; 37(11):1270-3. View abstract
  52. Montosi G, Donovan A, Totaro A, Garuti C, Pignatti E, Cassanelli S, Trenor CC, Gasparini P, Andrews NC, Pietrangelo A. Autosomal-dominant hemochromatosis is associated with a mutation in the ferroportin (SLC11A3) gene. J Clin Invest. 2001 Aug; 108(4):619-23. View abstract
  53. Fleming MD, Campagna DR, Haslett JN, Trenor CC, Andrews NC. A mutation in a mitochondrial transmembrane protein is responsible for the pleiotropic hematological and skeletal phenotype of flexed-tail (f/f) mice. Genes Dev. 2001 Mar 15; 15(6):652-7. View abstract
  54. Trenor CC, Campagna DR, Sellers VM, Andrews NC, Fleming MD. The molecular defect in hypotransferrinemic mice. Blood. 2000 Aug 01; 96(3):1113-8. View abstract
  55. Romero FJ, Martínez-Blasco A, Bosch-Morell F, Marín N, Trenor C, Romá J. Glycemic control and not protein kinase C inhibition prevents the early decrease of glutathione peroxidase activity in peripheral nerve of diabetic mice. J Peripher Nerv Syst. 1999; 4(3-4):265-9. View abstract
  56. Su MA, Trenor CC, Fleming JC, Fleming MD, Andrews NC. The G185R mutation disrupts function of the iron transporter Nramp2. Blood. 1998 Sep 15; 92(6):2157-63. View abstract
  57. Martínez-Blasco A, Bosch-Morell F, Trenor C, Romero FJ. Experimental diabetic neuropathy: role of oxidative stress and mechanisms involved. Biofactors. 1998; 8(1-2):41-3. View abstract
  58. Fleming MD, Trenor CC, Su MA, Foernzler D, Beier DR, Dietrich WF, Andrews NC. Microcytic anaemia mice have a mutation in Nramp2, a candidate iron transporter gene. Nat Genet. 1997 Aug; 16(4):383-6. View abstract
  59. Trenor C, Lin W, Andrews NC. Novel bacterial P-type ATPases with histidine-rich heavy-metal-associated sequences. Biochem Biophys Res Commun. 1994 Dec 30; 205(3):1644-50. View abstract