"Giving a child the ability to reach his or her full potential is something that motivates my work every day."

EDUCATION

Undergraduate Degree

  • Queen’s University , Kingston , Canada
Medical Degree
  • University of Toronto , Toronto , Canada

Graduate Degree

  • University of Toronto , Toronto , Canada

Graduate Degree

  • Neurosurgery-University of Toronto , Toronto , Canada

Fellowship

  • Pediatric Neurosurgery-Boston Children’s Hospital , Boston , Massachusetts

Philosophy of Care

I was inspired to become a neurosurgeon by my 10th grade biology teacher, who taught me to how push myself to accomplish my goals and exposed me to basic neuroscience research.

I remember seeing a video in high school of a patient being treated by an early form of deep brain stimulation (a field that I am now advancing in children). I was amazed at the ability of surgeons to alter brain function in a targeted way and alleviate a debilitating movement disorder. I have always been fascinated by the nervous system and neurological diseases, and knew at that point that I wanted to become a neurosurgeon. 

My approach to care reflects the work ethic that this influential teacher and my parents instilled in me as well as the satisfaction I get from helping a child suffering from neurologic illness. I find working with kids inspiring. They are usually much braver patients than adults and their potential for recovery is often great. Giving a child the ability to reach his or her full potential is something that motivates my work every day.

I was raised and trained in Canada and learned a lot about both science and working with kids from my parents, older brother and spouse. My father is a biologist, my mother is an elementary school teacher, my brother is a climate physicist and my wife is a pediatric nurse.

I have trained as a pilot as well as a SCUBA diver. I am proud to be practicing neurosurgery at Boston Children's Hospital because of the tremendous support and opportunity to pioneer new approaches. 

PROFESSIONAL HISTORY

My practice is focused mainly on functional disorders in children, where I am primarily advancing a treatment called deep brain stimulation to calm involuntary and disabiling motions in children with dystonia.

I hold both a medical degree and a PhD in neuroscience from the Institute of Medical Science at the University of Toronto, training that gives me a unique perspective on the treatment of neurosurgical patients. I completed the prestigious Shillito neurosurgical fellowship at Boston Children's Hospital in 2014, and am the founding surgical director of our department's movement disorders and deep brain stimulation program.

My clinical work focuses primarily on dystonia, a movement disorder in which faulty brain signals cause involuntary muscle contractions in children. I specialize in deep brain stimulation, a surgical procedure in which I implant electrodes on different targets in the brain to deliver electrical stimulation to those areas via a simultaneously-implanted pacemaker-like device called a neurostimulator. Deep brain stimulation is currently indicated for primary dystonia, and holds enormous future potential for other conditions.

I also run a general neurosurgical practice, encompassing areas such as brain tumors, neuroendoscopy and epilepsy surgeries. I am a passionate advocate for dystonia awareness and the potential application of deep brain stimulation for patients, and have been an invited speaker locally and internationally on the topic.

As a surgeon-scientist, I am interested in encouraging functional regeneration and repair of the brain using targeting therapies such as deep brain stimulation.  Through understanding mechanisms of adult neurogenesis and neurostimulation, I am hopeful that we will be able to harness intrinsic brain mechanisms to repair and restore damaged and diseased brain.

 

This clinician offers Virtual Visits (video consultations) for follow-up care in clinically-appropriate cases.

PUBLICATIONS

Publications powered by Harvard Catalyst Profiles

  1. Aravamuthan BR, Waugh JL, Stone SS. Deep brain stimulation for monogenic dystonia. Curr Opin Pediatr. 2017 Dec; 29(6):691-696. View abstract
  2. Hyde DE, Tomas-Fernandez X, Stone SS, Peters J, Warfield SK. Localization of stereo-electroencephalography signals using a finite difference complete electrode model. Conf Proc IEEE Eng Med Biol Soc. 2017 07; 2017:3600-3603. View abstract
  3. Xia F, Yiu A, Stone SSD, Oh S, Lozano AM, Josselyn SA, Frankland PW. Entorhinal Cortical Deep Brain Stimulation Rescues Memory Deficits in Both Young and Old Mice Genetically Engineered to Model Alzheimer's Disease. Neuropsychopharmacology. 2017 Dec; 42(13):2493-2503. View abstract
  4. Wang S, Stone S, Weil AG, Fallah A, Warf BC, Ragheb J, Bhatia S, Kulkarni AV. Comparative effectiveness of flexible versus rigid neuroendoscopy for endoscopic third ventriculostomy and choroid plexus cauterization: a propensity score-matched cohort and survival analysis. J Neurosurg Pediatr. 2017 May; 19(5):585-591. View abstract
  5. Bezchlibnyk YB, Stone SS, Hamani C, Lozano AM. High frequency stimulation of the infralimbic cortex induces morphological changes in rat hippocampal neurons. Brain Stimul. 2017 Mar - Apr; 10(2):315-323. View abstract
  6. Jernigan SC, Stone SS, Aronson JP, Putman M, Proctor MR. Episodic ventriculomegaly due to hypernatremia mimicking shunt malfunction: case report. J Neurosurg Pediatr. 2015 Oct; 16(4):406-9. View abstract
  7. Marano PJ, Stone SS, Mugamba J, Ssenyonga P, Warf EB, Warf BC. Reopening of an obstructed third ventriculostomy: long-term success and factors affecting outcome in 215 infants. J Neurosurg Pediatr. 2015 Apr; 15(4):399-405. View abstract
  8. Laxton AW, Stone S, Lozano AM. The neurosurgical treatment of Alzheimer's disease: a review. Stereotact Funct Neurosurg. 2014; 92(5):269-81. View abstract
  9. Stone SS, Warf BC. Combined endoscopic third ventriculostomy and choroid plexus cauterization as primary treatment for infant hydrocephalus: a prospective North American series. J Neurosurg Pediatr. 2014 Nov; 14(5):439-46. View abstract
  10. Gross BA, Stone SS, Smith ER. Occipital pial synangiosis. Acta Neurochir (Wien). 2014 Jul; 156(7):1297-300. View abstract
  11. Di Ieva A, Bruner E, Davidson J, Pisano P, Haider T, Stone SS, Cusimano MD, Tschabitscher M, Grizzi F. Cranial sutures: a multidisciplinary review. Childs Nerv Syst. 2013 Jun; 29(6):893-905. View abstract
  12. Girard JM, Stone SS, Lohi H, Blaszykowski C, Teixeira C, Turnbull J, Wang A, Draginov A, Wang P, Zhao XC, Ackerley CA, Frankland PW, Minassian BA. Phosphorylation prevents polyglucosan transport in Lafora disease. Neurology. 2012 Jul 03; 79(1):100-2. View abstract
  13. Stone SS, Teixeira CM, Devito LM, Zaslavsky K, Josselyn SA, Lozano AM, Frankland PW. Stimulation of entorhinal cortex promotes adult neurogenesis and facilitates spatial memory. J Neurosci. 2011 Sep 21; 31(38):13469-84. View abstract
  14. Hamani C, Stone SS, Garten A, Lozano AM, Winocur G. Memory rescue and enhanced neurogenesis following electrical stimulation of the anterior thalamus in rats treated with corticosterone. Exp Neurol. 2011 Nov; 232(1):100-4. View abstract
  15. Leslie AT, Akers KG, Krakowski AD, Stone SS, Sakaguchi M, Arruda-Carvalho M, Frankland PW. Impact of early adverse experience on complexity of adult-generated neurons. Transl Psychiatry. 2011 Aug 30; 1:e35. View abstract
  16. Hamani C, Mayberg H, Stone S, Laxton A, Haber S, Lozano AM. The subcallosal cingulate gyrus in the context of major depression. Biol Psychiatry. 2011 Feb 15; 69(4):301-8. View abstract
  17. Stone SS, Teixeira CM, Zaslavsky K, Wheeler AL, Martinez-Canabal A, Wang AH, Sakaguchi M, Lozano AM, Frankland PW. Functional convergence of developmentally and adult-generated granule cells in dentate gyrus circuits supporting hippocampus-dependent memory. Hippocampus. 2011 Dec; 21(12):1348-62. View abstract
  18. Hamani C, Dubiela FP, Soares JC, Shin D, Bittencourt S, Covolan L, Carlen PL, Laxton AW, Hodaie M, Stone SS, Ha Y, Hutchison WD, Lozano AM, Mello LE, Oliveira MG. Anterior thalamus deep brain stimulation at high current impairs memory in rats. Exp Neurol. 2010 Sep; 225(1):154-62. View abstract
  19. Stone SS, Rutka JT. Utility of neuronavigation and neuromonitoring in epilepsy surgery. Neurosurg Focus. 2008 Sep; 25(3):E17. View abstract
  20. Stone S, Bernstein M. Prospective error recording in surgery: an analysis of 1108 elective neurosurgical cases. Neurosurgery. 2007 Jun; 60(6):1075-80; discussion 1080-2. View abstract
  21. Hamani C, Stone S, Laxton A, Lozano AM. The pedunculopontine nucleus and movement disorders: anatomy and the role for deep brain stimulation. Parkinsonism Relat Disord. 2007; 13 Suppl 3:S276-80. View abstract