Robert Sundel, MD

Robert Sundel, MD

Medical Director, Center for Ambulatory Treatment and Clinical Research; Program Director, Rheumatology

Associate Professor, Harvard Medical School

  • Contact: 617-355-6117

  • Fax: 617-730-0310

Medical Services

Specialties

  • Innovative Therapy of Inflammatory Disorders
  • Kawasaki Disease and Other Vasculitides
  • Lyme Disease
  • Rheumatology Immunology Pediatrics

Departments

  • Medicine
  • Rheumatology

Programs

  • Rheumatology Program
  • Kawasaki Disease Program
  • Samara Jan Turkel Clinical Center
To schedule an appointment: Call 617-355-6117 or Request an Appointment

Experience and Education

Education

Undergraduate

Boston University, 1977

Boston, MA

Medical School

Boston University School of Medicine, 1982

Boston, MA

Internship

Babies Hospital, 1982-1983

New York, NY

Residency

Babies Hospital, 1983-1985

New York, NY

Fellowship

Boston Children's Hospital, 1986-1989

Boston, MA

Certifications

  • Allergy/Immunology, Pediatric Rheumatology, Pediatrics

Publications

Publications powered by Harvard Catalyst Profiles
  1. Henderson LA, Volpi S, Frugoni F, Janssen E, Kim S, Sundel RP, Dedeoglu F, Lo MS, Hazen MM, Beth Son M, Mathieu R, Zurakowski D, Yu N, Lebedeva T, Fuhlbrigge RC, Walter JE, Nee Lee Y, Nigrovic PA, Notarangelo LD. Next-Generation Sequencing Reveals Restriction and Clonotypic Expansion of Treg Cells in Juvenile Idiopathic Arthritis. Arthritis Rheumatol. 2016 Jul; 68(7):1758-68.
  2. Sundel RP. Kawasaki disease. Rheum Dis Clin North Am. 2015; 41(1):63-73, viii.
  3. Shakti D, Hehn R, Gauvreau K, Sundel RP, Newburger JW. Idiopathic pericarditis and pericardial effusion in children: contemporary epidemiology and management. J Am Heart Assoc. 2014 Dec; 3(6):e001483.
  4. Cornelissen L, Donado C, Kim J, Chiel L, Zurakowski D, Logan DE, Meier P, Sethna NF, Blankenburg M, Zernikow B, Sundel RP, Berde CB. Pain hypersensitivity in juvenile idiopathic arthritis: a quantitative sensory testing study. Pediatr Rheumatol Online J. 2014; 12:39.
  5. Wallace CA, Giannini EH, Spalding SJ, Hashkes PJ, O'Neil KM, Zeft AS, Szer IS, Ringold S, Brunner HI, Schanberg LE, Sundel RP, Milojevic DS, Punaro MG, Chira P, Gottlieb BS, Higgins GC, Ilowite NT, Kimura Y, Johnson A, Huang B, Lovell DJ. Clinically inactive disease in a cohort of children with new-onset polyarticular juvenile idiopathic arthritis treated with early aggressive therapy: time to achievement, total duration, and predictors. J Rheumatol. 2014 Jun; 41(6):1163-70.
  6. Henderson LA, Volpi S, Frugoni F, Kim S, Janssen E, Sundel RP, Dedeoglu F, Lo MS, Hazen MM, Mathieu R, Fuhlbrigge RC, Lee YN, Nigrovic PA, Notarangelo LD. A119: deep sequencing analysis of the T regulatory and T effector repertoire in juvenile idiopathic arthritis. Arthritis Rheumatol. 2014 Mar; 66 Suppl 11:S156.
  7. Lo MS, Zurakowski D, Son MB, Sundel RP. Hypergammaglobulinemia in the pediatric population as a marker for underlying autoimmune disease: a retrospective cohort study. Pediatr Rheumatol Online J. 2013; 11(1):42.
  8. Kentsis A, Shulman A, Ahmed S, Brennan E, Monuteaux MC, Lee YH, Lipsett S, Paulo JA, Dedeoglu F, Fuhlbrigge R, Bachur R, Bradwin G, Arditi M, Sundel RP, Newburger JW, Steen H, Kim S. Urine proteomics for discovery of improved diagnostic markers of Kawasaki disease. EMBO Mol Med. 2013 Feb; 5(2):210-20.
  9. Borzutzky A, Stern S, Reiff A, Zurakowski D, Steinberg EA, Dedeoglu F, Sundel RP. Pediatric chronic nonbacterial osteomyelitis. Pediatrics. 2012 Nov; 130(5):e1190-7.
  10. Sundel RP. Paediatric rheumatic disease: Classification warfare. Nat Rev Rheumatol. 2012 Oct; 8(10):570-2.
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  12. Ercan A, Barnes MG, Hazen M, Tory H, Henderson L, Dedeoglu F, Fuhlbrigge RC, Grom A, Holm IA, Kellogg M, Kim S, Adamczyk B, Rudd PM, Son MB, Sundel RP, Foell D, Glass DN, Thompson SD, Nigrovic PA. Multiple juvenile idiopathic arthritis subtypes demonstrate proinflammatory IgG glycosylation. Arthritis Rheum. 2012 Sep; 64(9):3025-33.
  13. Sundel R, Solomons N, Lisk L. Efficacy of mycophenolate mofetil in adolescent patients with lupus nephritis: evidence from a two-phase, prospective randomized trial. Lupus. 2012 Nov; 21(13):1433-43.
  14. Wallace CA, Giannini EH, Spalding SJ, Hashkes PJ, O'Neil KM, Zeft AS, Szer IS, Ringold S, Brunner HI, Schanberg LE, Sundel RP, Milojevic D, Punaro MG, Chira P, Gottlieb BS, Higgins GC, Ilowite NT, Kimura Y, Hamilton S, Johnson A, Huang B, Lovell DJ. Trial of early aggressive therapy in polyarticular juvenile idiopathic arthritis. Arthritis Rheum. 2012 Jun; 64(6):2012-21.
  15. Sundel RP. Putting collagen back in the collagen vascular disorders. Rheumatology (Oxford). 2011 Dec; 50 Suppl 5:v60-2.
  16. Glotzbecker MP, Kocher MS, Sundel RP, Shore BJ, Spencer SA, Kasser JR. Primary lyme arthritis of the pediatric hip. J Pediatr Orthop. 2011 Oct-Nov; 31(7):787-90.
  17. Son MB, Gauvreau K, Burns JC, Corinaldesi E, Tremoulet AH, Watson VE, Baker A, Fulton DR, Sundel RP, Newburger JW. Infliximab for intravenous immunoglobulin resistance in Kawasaki disease: a retrospective study. J Pediatr. 2011 Apr; 158(4):644-649.e1.
  18. Son MB, Sundel RP. Musculoskeletal causes of pediatric chest pain. Pediatr Clin North Am. 2010 Dec; 57(6):1385-95.
  19. Tory HO, Zurakowski D, Sundel RP. Outcomes of children treated for Lyme arthritis: results of a large pediatric cohort. J Rheumatol. 2010 May; 37(5):1049-55.
  20. Yellen ES, Gauvreau K, Takahashi M, Burns JC, Shulman S, Baker AL, Innocentini N, Zambetti C, Pancheri JM, Ostrow A, Frazer JR, Sundel RP, Fulton DR, Newburger JW. Performance of 2004 American Heart Association recommendations for treatment of Kawasaki disease. Pediatrics. 2010 Feb; 125(2):e234-41.
  21. Cimaz R, Sundel R. Atypical and incomplete Kawasaki disease. Best Pract Res Clin Rheumatol. 2009 Oct; 23(5):689-97.
  22. Sundel RP. Editorial: Do no harm--first but not only. Curr Opin Rheumatol. 2009 Sep; 21(5):531-2.
  23. Son MB, Gauvreau K, Ma L, Baker AL, Sundel RP, Fulton DR, Newburger JW. Treatment of Kawasaki disease: analysis of 27 US pediatric hospitals from 2001 to 2006. Pediatrics. 2009 Jul; 124(1):1-8.
  24. Kim S, El-Hallak M, Dedeoglu F, Zurakowski D, Fuhlbrigge RC, Sundel RP. Complete and sustained remission of juvenile dermatomyositis resulting from aggressive treatment. Arthritis Rheum. 2009 Jun; 60(6):1825-30.
  25. Lee EY, Sundel RP, Kim S, Zurakowski D, Kleinman PK. MRI findings of juvenile psoriatic arthritis. Skeletal Radiol. 2008 Nov; 37(11):987-96.
  26. El-Hallak M, Giani T, Yeniay BS, Jacobs KE, Kim S, Sundel RP, Dedeoglu F. Chronic minocycline-induced autoimmunity in children. J Pediatr. 2008 Sep; 153(3):314-9.
  27. Stoll ML, Lio P, Sundel RP, Nigrovic PA. Comparison of Vancouver and International League of Associations for rheumatology classification criteria for juvenile psoriatic arthritis. Arthritis Rheum. 2008 Jan 15; 59(1):51-8.
  28. Minich LL, Sleeper LA, Atz AM, McCrindle BW, Lu M, Colan SD, Printz BF, Klein GL, Sundel RP, Takahashi M, Li JS, Vetter VL, Newburger JW. Delayed diagnosis of Kawasaki disease: what are the risk factors? Pediatrics. 2007 Dec; 120(6):e1434-40.
  29. Miyake CY, Gauvreau K, Tani LY, Sundel RP, Newburger JW. Characteristics of children discharged from hospitals in the United States in 2000 with the diagnosis of acute rheumatic fever. Pediatrics. 2007 Sep; 120(3):503-8.
  30. Dedeoglu F, Sundel RP. Vasculitis in children. Rheum Dis Clin North Am. 2007 Aug; 33(3):555-83.
  31. El-Hallak M, Binstadt BA, Leichtner AM, Bennett CM, Neufeld EJ, Fuhlbrigge RC, Zurakowski D, Sundel RP. Clinical effects and safety of rituximab for treatment of refractory pediatric autoimmune diseases. J Pediatr. 2007 Apr; 150(4):376-82.
  32. Newburger JW, Sleeper LA, McCrindle BW, Minich LL, Gersony W, Vetter VL, Atz AM, Li JS, Takahashi M, Baker AL, Colan SD, Mitchell PD, Klein GL, Sundel RP. Randomized trial of pulsed corticosteroid therapy for primary treatment of Kawasaki disease. N Engl J Med. 2007 Feb 15; 356(7):663-75.
  33. Popper SJ, Shimizu C, Shike H, Kanegaye JT, Newburger JW, Sundel RP, Brown PO, Burns JC, Relman DA. Gene-expression patterns reveal underlying biological processes in Kawasaki disease. Genome Biol. 2007; 8(12):R261.
  34. Martini G, Foeldvari I, Russo R, Cuttica R, Eberhard A, Ravelli A, Lehman TJ, de Oliveira SK, Susic G, Lyskina G, Nemcova D, Sundel R, Falcini F, Girschick H, Lotito AP, Buoncompagni A, Sztajnbok F, Al-Mayouf SM, Orbàn I, Ferri C, Athreya BH, Woo P, Zulian F. Systemic sclerosis in childhood: clinical and immunologic features of 153 patients in an international database. Arthritis Rheum. 2006 Dec; 54(12):3971-8.
  35. Stoll ML, Zurakowski D, Nigrovic LE, Nichols DP, Sundel RP, Nigrovic PA. Patients with juvenile psoriatic arthritis comprise two distinct populations. Arthritis Rheum. 2006 Nov; 54(11):3564-72.
  36. Burns JC, Shimizu C, Shike H, Newburger JW, Sundel RP, Baker AL, Matsubara T, Ishikawa Y, Brophy VA, Cheng S, Grow MA, Steiner LL, Kono N, Cantor RM. Family-based association analysis implicates IL-4 in susceptibility to Kawasaki disease. Genes Immun. 2005 Aug; 6(5):438-44.
  37. Binstadt BA, Levine JC, Nigrovic PA, Gauvreau K, Dedeoglu F, Fuhlbrigge RC, Weindling SN, Newburger JW, Sundel RP. Coronary artery dilation among patients presenting with systemic-onset juvenile idiopathic arthritis. Pediatrics. 2005 Jul; 116(1):e89-93.
  38. Ecklund K, Vargas S, Zurakowski D, Sundel RP. MRI features of Lyme arthritis in children. AJR Am J Roentgenol. 2005 Jun; 184(6):1904-9.
  39. Dedeoglu F, Sundel RP. Vasculitis in children. Pediatr Clin North Am. 2005 Apr; 52(2):547-75, vii.
  40. Lehman TJ, Schechter SJ, Sundel RP, Oliveira SK, Huttenlocher A, Onel KB. Thalidomide for severe systemic onset juvenile rheumatoid arthritis: A multicenter study. J Pediatr. 2004 Dec; 145(6):856-7.
  41. Binstadt BA, Caldas AM, Turvey SE, Stone KD, Weinstein HJ, Jackson J, Fuhlbrigge RC, Sundel RP. Rituximab therapy for multisystem autoimmune diseases in pediatric patients. J Pediatr. 2003 Nov; 143(5):598-604.
  42. Sundel RP, Baker AL, Fulton DR, Newburger JW. Corticosteroids in the initial treatment of Kawasaki disease: report of a randomized trial. J Pediatr. 2003 Jun; 142(6):611-6.
  43. Kocher MS, Mandiga R, Murphy JM, Goldmann D, Harper M, Sundel R, Ecklund K, Kasser JR. A clinical practice guideline for treatment of septic arthritis in children: efficacy in improving process of care and effect on outcome of septic arthritis of the hip. J Bone Joint Surg Am. 2003 Jun; 85-A(6):994-9.
  44. Nigrovic PA, Fuhlbrigge RC, Sundel RP. Raynaud's phenomenon in children: a retrospective review of 123 patients. Pediatrics. 2003 Apr; 111(4 Pt 1):715-21.
  45. Baker AL, Gauvreau K, Newburger JW, Sundel RP, Fulton DR, Jenkins KJ. Physical and psychosocial health in children who have had Kawasaki disease. Pediatrics. 2003 Mar; 111(3):579-83.
  46. Sundel RP. Update on the treatment of Kawasaki disease in childhood. Curr Rheumatol Rep. 2002 Dec; 4(6):474-82.
  47. Lee JM, Sundel RP, Liang MG. Fibroblastic rheumatism: case report and review of the literature. Pediatr Dermatol. 2002 Nov-Dec; 19(6):532-5.
  48. Fisler RE, Liang MG, Fuhlbrigge RC, Yalcindag A, Sundel RP. Aggressive management of juvenile dermatomyositis results in improved outcome and decreased incidence of calcinosis. J Am Acad Dermatol. 2002 Oct; 47(4):505-11.
  49. Sundel R, Szer I. Vasculitis in childhood. Rheum Dis Clin North Am. 2002 Aug; 28(3):625-54.
  50. Palmer GM, Sundel R, Berde CB, Sethna NF. Prolonged sensory and motor deficit following short-term lumbar epidural analgesia in a patient with mixed connective tissue disease. J Pain Symptom Manage. 2002 Feb; 23(2):89-92.
  51. Yalcindag A, Sundel R. Vasculitis in childhood. Curr Opin Rheumatol. 2001 Sep; 13(5):422-7.
  52. Nigrovic PA, Sundel RP. Treatment of TRAPS with etanercept: use in pediatrics. Clin Exp Rheumatol. 2001 Jul-Aug; 19(4):484-5.
  53. Ravekes WJ, Colan SD, Gauvreau K, Baker AL, Sundel RP, van der Velde ME, Fulton DR, Newburger JW. Aortic root dilation in Kawasaki disease. Am J Cardiol. 2001 Apr 1; 87(7):919-22.
  54. Eberhard BA, Sundel RP, Newburger JW, Baker A, Fuhlbrigge RC, Burns JC, Gellis SE. Psoriatic eruption in Kawasaki disease. J Pediatr. 2000 Oct; 137(4):578-80.
  55. O'Brien M, Parness IA, Neufeld EJ, Baker AL, Sundel RP, Newburger JW. Ticlopidine plus aspirin for coronary thrombosis in Kawasaki disease. Pediatrics. 2000 May; 105(5):E64.
  56. Barron KS, Shulman ST, Rowley A, Taubert K, Myones BL, Meissner HC, Peters J, Duffy CE, Silverman E, Sundel R. Report of the National Institutes of Health Workshop on Kawasaki Disease. J Rheumatol. 1999 Jan; 26(1):170-90.
  57. Bousvaros A, Sundel R, Thorne GM, McIntosh K, Cohen M, Erdman DD, Perez-Atayde A, Finkel TH, Colin AA. Parvovirus B19-associated interstitial lung disease, hepatitis, and myositis. Pediatr Pulmonol. 1998 Nov; 26(5):365-9.
  58. Wang TJ, Sangha O, Phillips CB, Wright EA, Lew RA, Fossel AH, Fossel K, Shadick NA, Liang MH, Sundel RP. Outcomes of children treated for Lyme disease. J Rheumatol. 1998 Nov; 25(11):2249-53.
  59. de Zorzi A, Colan SD, Gauvreau K, Baker AL, Sundel RP, Newburger JW. Coronary artery dimensions may be misclassified as normal in Kawasaki disease. J Pediatr. 1998 Aug; 133(2):254-8.
  60. Beiser AS, Takahashi M, Baker AL, Sundel RP, Newburger JW. A predictive instrument for coronary artery aneurysms in Kawasaki disease. US Multicenter Kawasaki Disease Study Group. Am J Cardiol. 1998 May 1; 81(9):1116-20.
  61. Giannini EH, Lovell DJ, Silverman ED, Sundel RP, Tague BL, Ruperto N. Intravenous immunoglobulin in the treatment of polyarticular juvenile rheumatoid arthritis: a phase I/II study. Pediatric Rheumatology Collaborative Study Group. J Rheumatol. 1996 May; 23(5):919-24.
  62. Wright DA, Newburger JW, Baker A, Sundel RP. Treatment of immune globulin-resistant Kawasaki disease with pulsed doses of corticosteroids. J Pediatr. 1996 Jan; 128(1):146-9.
  63. Jaramillo D, Treves ST, Kasser JR, Harper M, Sundel R, Laor T. Osteomyelitis and septic arthritis in children: appropriate use of imaging to guide treatment. AJR Am J Roentgenol. 1995 Aug; 165(2):399-403.
  64. Mandle R, Baron C, Roux E, Sundel R, Gelfand J, Aulak K, Davis AE, Rosen FS, Bing DH. Acquired C1 inhibitor deficiency as a result of an autoantibody to the reactive center region of C1 inhibitor. J Immunol. 1994 May 1; 152(9):4680-5.
  65. Sundel RP, Newburger JW. Kawasaki disease and its cardiac sequelae. Hosp Pract (Off Ed). 1993 Nov 15; 28(11):51-4, 57-60, 64-6.
  66. Sundel RP, Burns JC, Baker A, Beiser AS, Newburger JW. Gamma globulin re-treatment in Kawasaki disease. J Pediatr. 1993 Oct; 123(4):657-9.
  67. Lande MB, Gleeson JG, Sundel RP. Kawasaki disease and acute renal failure. Pediatr Nephrol. 1993 Oct; 7(5):593.
  68. Sundel RP, Cleveland SS, Beiser AS, Newburger JW, McGill T, Baker AL, Koren G, Novak RE, Harris JP, Burns JC. Audiologic profiles of children with Kawasaki disease. Am J Otol. 1992 Nov; 13(6):512-5.
  69. Koren G, Silverman E, Sundel R, Edney P, Newburger JW, Klein J, Robieux I, Laxer R, Giesbrecht E, Burns JC. Decreased protein binding of salicylates in Kawasaki disease. J Pediatr. 1991 Mar; 118(3):456-9.
  70. Sundel RP, Newburger JW, McGill T, Cleveland SS, Miller WW, Berry B, Klein AM, Burns JC. Sensorineural hearing loss associated with Kawasaki disease. J Pediatr. 1990 Sep; 117(3):371-7.
  71. Sundel R, Leung DY. Kawasaki disease. Curr Opin Rheumatol. 1990 Feb; 2(1):81-6.
To schedule an appointment: Call 617-355-6117 or Request an Appointment

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