• Williams College

Medical School

  • University of Rochester , Rochester , NY


  • Boston City Hospital , Boston , MA

Graduate Degree

  • Boston Children's Hospital , Boston , MA


Pediatric Endocrinology - Adolescent Medicine
  • Boston Children's Hospital , Boston , MA



Publications powered by Harvard Catalyst Profiles

  1. Spratt DI, Stewart II, Savage C, Craig W, Spack NP, Chandler DW, Spratt LV, Eimicke T, Olshan JS. Subcutaneous Injection of Testosterone Is an Effective and Preferred Alternative to Intramuscular Injection: Demonstration in Female-to-Male Transgender Patients. J Clin Endocrinol Metab. 2017 07 01; 102(7):2349-2355. View abstract
  2. Strang JF, Meagher H, Kenworthy L, de Vries ALC, Menvielle E, Leibowitz S, Janssen A, Cohen-Kettenis P, Shumer DE, Edwards-Leeper L, Pleak RR, Spack N, Karasic DH, Schreier H, Balleur A, Tishelman A, Ehrensaft D, Rodnan L, Kuschner ES, Mandel F, Caretto A, Lewis HC, Anthony LG. Initial Clinical Guidelines for Co-Occurring Autism Spectrum Disorder and Gender Dysphoria or Incongruence in Adolescents. J Clin Child Adolesc Psychol. 2018 Jan-Feb; 47(1):105-115. View abstract
  3. Shumer DE, Nokoff NJ, Spack NP. Advances in the Care of Transgender Children and Adolescents. Adv Pediatr. 2016 08; 63(1):79-102. View abstract
  4. Tishelman AC, Kaufman R, Edwards-Leeper L, Mandel FH, Shumer DE, Spack NP. Reply to comment on "Serving Transgender Youth: Challenges, Dilemmas, and Clinical Examples" by Tishelman et al. (2015). Prof Psychol Res Pr. 2015 Aug; 46(4):307. View abstract
  5. Tishelman AC, Kaufman R, Edwards-Leeper L, Mandel FH, Shumer DE, Spack NP. Serving Transgender Youth: Challenges, Dilemmas and Clinical Examples. Prof Psychol Res Pr. 2015; 46(1):37-45. View abstract
  6. Shumer DE, Spack NP. Paediatrics: Transgender medicine--long-term outcomes from 'the Dutch model'. Nat Rev Urol. 2015 Jan; 12(1):12-3. View abstract
  7. Spack NP. Care for transgender persons--reply. JAMA. 2013 May 22; 309(20):2093-4. View abstract
  8. Spack NP. Management of transgenderism. JAMA. 2013 Feb 06; 309(5):478-84. View abstract
  9. Shumer DE, Spack NP. Current management of gender identity disorder in childhood and adolescence: guidelines, barriers and areas of controversy. Curr Opin Endocrinol Diabetes Obes. 2013 Feb; 20(1):69-73. View abstract
  10. Spack NP, Edwards-Leeper L, Feldman HA, Leibowitz S, Mandel F, Diamond DA, Vance SR. Children and adolescents with gender identity disorder referred to a pediatric medical center. Pediatrics. 2012 Mar; 129(3):418-25. View abstract
  11. Edwards-Leeper L, Spack NP. Psychological evaluation and medical treatment of transgender youth in an interdisciplinary "Gender Management Service" (GeMS) in a major pediatric center. J Homosex. 2012; 59(3):321-36. View abstract
  12. Leibowitz SF, Spack NP. The development of a gender identity psychosocial clinic: treatment issues, logistical considerations, interdisciplinary cooperation, and future initiatives. Child Adolesc Psychiatr Clin N Am. 2011 Oct; 20(4):701-24. View abstract
  13. Perrin E, Smith N, Davis C, Spack N, Stein MT. Gender variant and gender dysphoria in two young children. J Dev Behav Pediatr. 2010 Feb-Mar; 31(2):161-4. View abstract
  14. Hembree WC, Cohen-Kettenis P, Delemarre-van de Waal HA, Gooren LJ, Meyer WJ, Spack NP, Tangpricha V, Montori VM. Endocrine treatment of transsexual persons: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2009 Sep; 94(9):3132-54. View abstract
  15. Goddard DS, Liang MG, Chamlin SL, Svoren BM, Spack NP, Mulliken JB. Hypopituitarism in PHACES Association. Pediatr Dermatol. 2006 Sep-Oct; 23(5):476-80. View abstract
  16. Spack N. Transgenderism. Med Ethics (Burlingt Mass). 2005; 12(3):1-2, 12. View abstract
  17. Poussaint TY, Barnes PD, Anthony DC, Spack N, Scott RM, Tarbell NJ. Hemorrhagic pituitary adenomas of adolescence. AJNR Am J Neuroradiol. 1996 Nov-Dec; 17(10):1907-12. View abstract
  18. Feke GT, Buzney SM, Ogasawara H, Fujio N, Goger DG, Spack NP, Gabbay KH. Retinal circulatory abnormalities in type 1 diabetes. Invest Ophthalmol Vis Sci. 1994 Jun; 35(7):2968-75. View abstract
  19. Grace E, Spack N. Teaching teenagers to cope. Internist. 1979 Oct; 20(8):6-8. View abstract
  20. Gabbay KH, Spack N, Loo S, Hirsch HJ, Ackil AA. Aldose reductase inhibition: studies with alrestatin. Metabolism. 1979 Apr; 28(4 Suppl 1):471-6. View abstract