Norman Spack, MD

Norman P Spack, MD

Associate Physician in Medicine; Emeritus, Gender Management Service

Associate Clinical Professor of Pediatrics, Harvard Medical School

    Contact: 617-355-4367
  • Fax: 617-730-9299

Medical Services


  • Disorders of Sex Development
  • GeMS


  • Endocrinology
  • Medicine


  • English


  • Disorders of Sex Development (DSD) and Gender Management Service (GeMS)
To schedule an appointment: Call 617-355-4367 or Request an Appointment

Experience and Education



Williams College, 1965

Medical School

University of Rochester, 1969

Rochester, NY

Pediatrics Internship

Boston City Hospital, 1970

Boston, MA

Pediatrics Residency

Boston Children's Hospital, 1972

Boston, MA

Fellowship, Pediatric Endocrinology/ Adolescent Medicine

Boston Children's Hospital, 1976

Boston, MA



Publications powered by Harvard Catalyst Profiles
  1. Spratt DI, Stewart II, Savage C, Craig W, Spack NP, Chandler DW, Spratt LV, Eimicke T, Olshan JS. Subcutaneous Injection of Testosterone Is an Effective and Preferred Alternative to Intramuscular Injection: Demonstration in Female-to-Male Transgender Patients. J Clin Endocrinol Metab. 2017 Jul 01; 102(7):2349-2355.
  2. Strang JF, Meagher H, Kenworthy L, de Vries ALC, Menvielle E, Leibowitz S, Janssen A, Cohen-Kettenis P, Shumer DE, Edwards-Leeper L, Pleak RR, Spack N, Karasic DH, Schreier H, Balleur A, Tishelman A, Ehrensaft D, Rodnan L, Kuschner ES, Mandel F, Caretto A, Lewis HC, Anthony LG. Initial Clinical Guidelines for Co-Occurring Autism Spectrum Disorder and Gender Dysphoria or Incongruence in Adolescents. J Clin Child Adolesc Psychol. 2018 Jan-Feb; 47(1):105-115.
  3. Shumer DE, Nokoff NJ, Spack NP. Advances in the Care of Transgender Children and Adolescents. Adv Pediatr. 2016 08; 63(1):79-102.
  4. Tishelman AC, Kaufman R, Edwards-Leeper L, Mandel FH, Shumer DE, Spack NP. Reply to comment on "Serving Transgender Youth: Challenges, Dilemmas, and Clinical Examples" by Tishelman et al. (2015). Prof Psychol Res Pr. 2015 Aug; 46(4):307.
  5. Tishelman AC, Kaufman R, Edwards-Leeper L, Mandel FH, Shumer DE, Spack NP. Serving Transgender Youth: Challenges, Dilemmas and Clinical Examples. Prof Psychol Res Pr. 2015; 46(1):37-45.
  6. Shumer DE, Spack NP. Paediatrics: Transgender medicine--long-term outcomes from 'the Dutch model'. Nat Rev Urol. 2015 Jan; 12(1):12-3.
  7. Spack NP. Care for transgender persons--reply. JAMA. 2013 May 22; 309(20):2093-4.
  8. Spack NP. Management of transgenderism. JAMA. 2013 Feb 06; 309(5):478-84.
  9. Shumer DE, Spack NP. Current management of gender identity disorder in childhood and adolescence: guidelines, barriers and areas of controversy. Curr Opin Endocrinol Diabetes Obes. 2013 Feb; 20(1):69-73.
  10. Spack NP, Edwards-Leeper L, Feldman HA, Leibowitz S, Mandel F, Diamond DA, Vance SR. Children and adolescents with gender identity disorder referred to a pediatric medical center. Pediatrics. 2012 Mar; 129(3):418-25.
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  12. Edwards-Leeper L, Spack NP. Psychological evaluation and medical treatment of transgender youth in an interdisciplinary "Gender Management Service" (GeMS) in a major pediatric center. J Homosex. 2012; 59(3):321-36.
  13. Leibowitz SF, Spack NP. The development of a gender identity psychosocial clinic: treatment issues, logistical considerations, interdisciplinary cooperation, and future initiatives. Child Adolesc Psychiatr Clin N Am. 2011 Oct; 20(4):701-24.
  14. Perrin E, Smith N, Davis C, Spack N, Stein MT. Gender variant and gender dysphoria in two young children. J Dev Behav Pediatr. 2010 Feb-Mar; 31(2):161-4.
  15. Hembree WC, Cohen-Kettenis P, Delemarre-van de Waal HA, Gooren LJ, Meyer WJ, Spack NP, Tangpricha V, Montori VM. Endocrine treatment of transsexual persons: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2009 Sep; 94(9):3132-54.
  16. Goddard DS, Liang MG, Chamlin SL, Svoren BM, Spack NP, Mulliken JB. Hypopituitarism in PHACES Association. Pediatr Dermatol. 2006 Sep-Oct; 23(5):476-80.
  17. Spack N. Transgenderism. Med Ethics (Burlingt Mass). 2005; 12(3):1-2, 12.
  18. Poussaint TY, Barnes PD, Anthony DC, Spack N, Scott RM, Tarbell NJ. Hemorrhagic pituitary adenomas of adolescence. AJNR Am J Neuroradiol. 1996 Nov-Dec; 17(10):1907-12.
  19. Feke GT, Buzney SM, Ogasawara H, Fujio N, Goger DG, Spack NP, Gabbay KH. Retinal circulatory abnormalities in type 1 diabetes. Invest Ophthalmol Vis Sci. 1994 Jun; 35(7):2968-75.
  20. Grace E, Spack N. Teaching teenagers to cope. Internist. 1979 Oct; 20(8):6-8.
  21. Gabbay KH, Spack N, Loo S, Hirsch HJ, Ackil AA. Aldose reductase inhibition: studies with alrestatin. Metabolism. 1979 Apr; 28(4 Suppl 1):471-6.
To schedule an appointment: Call 617-355-4367 or Request an Appointment


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