Jeffrey Neil MD PhD

Jeffrey Joseph Neil, MD, PhD

Associate in Neurology

Professor in Residence of Neurology, Harvard Medical School

    Contact: 617-355-8994
  • Fax: 617-730-0279

Medical Services

Specialties

  • Neonatal Neurology

Departments

  • Neurology

Languages

  • English

Programs

  • Fetal-Neonatal Neurology Program
To schedule an appointment: Call 617-355-8994 or Request an Appointment

Experience and Education

Education

Undergraduate

Washington University, 1977

St. Louis, Missouri

Medical School

Washington University, 1984

St. Louis, Missouri

Residency

Pediatrics-St. Louis Children's Hospital, 1986

St. Louis, Missouri

Fellowship

Pediatric Neurology-St. Louis Children's Hospital, 1989

St. Louis, Missouri

Research Fellowship

Magnetic Resonance Imaging Methods-Washington University, 1990

St. Louis, Missouri

Attending

Pediatric Neuromuscular Clinic, Pediatric Neurology-St. Louis Children's Hospital, 2010

St. Louis, Missouri

Certifications

  • American Board of Psychiatry and Neurology with Special Qualification in Child Neurology

  • Pediatric Neurology

Publications

Publications powered by Harvard Catalyst Profiles
  1. Eaton-Rosen Z, Scherrer B, Melbourne A, Ourselin S, Neil JJ, Warfield SK. Investigating the maturation of microstructure and radial orientation in the preterm human cortex with diffusion MRI. Neuroimage. 2017 Aug 08; 162:65-72.
  2. Anderson PJ, Treyvaud K, Neil JJ, Cheong JLY, Hunt RW, Thompson DK, Lee KJ, Doyle LW, Inder TE. Associations of Newborn Brain Magnetic Resonance Imaging with Long-Term Neurodevelopmental Impairments in Very Preterm Children. J Pediatr. 2017 Aug; 187:58-65.e1.
  3. Brouwer MJ, Kersbergen KJ, van Kooij BJM, Benders MJNL, van Haastert IC, Koopman-Esseboom C, Neil JJ, de Vries LS, Kidokoro H, Inder TE, Groenendaal F. Preterm brain injury on term-equivalent age MRI in relation to perinatal factors and neurodevelopmental outcome at two years. PLoS One. 2017; 12(5):e0177128.
  4. Walsh BH, Neil J, Morey J, Yang E, Silvera MV, Inder TE, Ortinau C. The Frequency and Severity of Magnetic Resonance Imaging Abnormalities in Infants with Mild Neonatal Encephalopathy. J Pediatr. 2017 Aug; 187:26-33.e1.
  5. Shany E, Inder TE, Goshen S, Lee I, Neil JJ, Smyser CD, Doyle LW, Anderson PJ, Shimony JS. Diffusion Tensor Tractography of the Cerebellar Peduncles in Prematurely Born 7-Year-Old Children. Cerebellum. 2017 Apr; 16(2):314-325.
  6. Vesoulis ZA, McPherson C, Neil JJ, Mathur AM, Inder TE. Early High-Dose Caffeine Increases Seizure Burden in Extremely Preterm Neonates: A Preliminary Study. J Caffeine Res. 2016 Sep 01; 6(3):101-107.
  7. Monson BB, Anderson PJ, Matthews LG, Neil JJ, Kapur K, Cheong JL, Doyle LW, Thompson DK, Inder TE. Examination of the Pattern of Growth of Cerebral Tissue Volumes From Hospital Discharge to Early Childhood in Very Preterm Infants. JAMA Pediatr. 2016 Aug 01; 170(8):772-9.
  8. Smyser CD, Dosenbach NU, Smyser TA, Snyder AZ, Rogers CE, Inder TE, Schlaggar BL, Neil JJ. Prediction of brain maturity in infants using machine-learning algorithms. Neuroimage. 2016 Aug 01; 136:1-9.
  9. Shimony JS, Smyser CD, Wideman G, Alexopoulos D, Hill J, Harwell J, Dierker D, Van Essen DC, Inder TE, Neil JJ. Comparison of cortical folding measures for evaluation of developing human brain. Neuroimage. 2016 Jan 15; 125:780-790.
  10. Rogers CE, Smyser T, Smyser CD, Shimony J, Inder TE, Neil JJ. Regional white matter development in very preterm infants: perinatal predictors and early developmental outcomes. Pediatr Res. 2016 Jan; 79(1-1):87-95.
  11. Show all
  12. McPherson C, Haslam M, Pineda R, Rogers C, Neil JJ, Inder TE. Brain Injury and Development in Preterm Infants Exposed to Fentanyl. Ann Pharmacother. 2015 Dec; 49(12):1291-7.
  13. Smyser TA, Smyser CD, Rogers CE, Gillespie SK, Inder TE, Neil JJ. Cortical Gray and Adjacent White Matter Demonstrate Synchronous Maturation in Very Preterm Infants. Cereb Cortex. 2016 Aug; 26(8):3370-3378.
  14. Steinhorn R, McPherson C, Anderson PJ, Neil J, Doyle LW, Inder T. Neonatal morphine exposure in very preterm infants-cerebral development and outcomes. J Pediatr. 2015 May; 166(5):1200-1207.e4.
  15. McPherson C, Neil JJ, Tjoeng TH, Pineda R, Inder TE. A pilot randomized trial of high-dose caffeine therapy in preterm infants. Pediatr Res. 2015 Aug; 78(2):198-204.
  16. Smyser CD, Neil JJ. Use of resting-state functional MRI to study brain development and injury in neonates. Semin Perinatol. 2015 Mar; 39(2):130-40.
  17. Zhang Y, Inder TE, Neil JJ, Dierker DL, Alexopoulos D, Anderson PJ, Van Essen DC. Cortical structural abnormalities in very preterm children at 7 years of age. Neuroimage. 2015 Apr 01; 109:469-79.
  18. Engelhardt E, Inder TE, Alexopoulos D, Dierker DL, Hill J, Van Essen D, Neil JJ. Regional impairments of cortical folding in premature infants. Ann Neurol. 2015 Jan; 77(1):154-62.
  19. Gholipour A, Estroff JA, Barnewolt CE, Robertson RL, Grant PE, Gagoski B, Warfield SK, Afacan O, Connolly SA, Neil JJ, Wolfberg A, Mulkern RV. Fetal MRI: A Technical Update with Educational Aspirations. Concepts Magn Reson Part A Bridg Educ Res. 2014 Nov; 43(6):237-266.
  20. Smyser CD, Snyder AZ, Shimony JS, Mitra A, Inder TE, Neil JJ. Resting-State Network Complexity and Magnitude Are Reduced in Prematurely Born Infants. Cereb Cortex. 2016 Jan; 26(1):322-333.
  21. Paul RA, Smyser CD, Rogers CE, English I, Wallendorf M, Alexopoulos D, Meyer EJ, Van Essen DC, Neil JJ, Inder TE. An allometric scaling relationship in the brain of preterm infants. Ann Clin Transl Neurol. 2014 Nov; 1(11):933-7.
  22. Kidokoro H, Anderson PJ, Doyle LW, Woodward LJ, Neil JJ, Inder TE. Brain injury and altered brain growth in preterm infants: predictors and prognosis. Pediatrics. 2014 Aug; 134(2):e444-53.
  23. Lee I, Neil JJ, Huettner PC, Smyser CD, Rogers CE, Shimony JS, Kidokoro H, Mysorekar IU, Inder TE. The impact of prenatal and neonatal infection on neurodevelopmental outcomes in very preterm infants. J Perinatol. 2014 Oct; 34(10):741-7.
  24. Ortinau C, Neil J. The neuroanatomy of prematurity: normal brain development and the impact of preterm birth. Clin Anat. 2015 Mar; 28(2):168-83.
  25. Cameron FJ, Scratch SE, Nadebaum C, Northam EA, Koves I, Jennings J, Finney K, Neil JJ, Wellard RM, Mackay M, Inder TE. Neurological consequences of diabetic ketoacidosis at initial presentation of type 1 diabetes in a prospective cohort study of children. Diabetes Care. 2014 Jun; 37(6):1554-62.
  26. Reynolds LC, Inder TE, Neil JJ, Pineda RG, Rogers CE. Maternal obesity and increased risk for autism and developmental delay among very preterm infants. J Perinatol. 2014 Sep; 34(9):688-92.
  27. Tao JD, Neil JJ. Advanced magnetic resonance imaging techniques in the preterm brain: methods and applications. Curr Pediatr Rev. 2014; 10(1):56-64.
  28. Pineda RG, Neil J, Dierker D, Smyser CD, Wallendorf M, Kidokoro H, Reynolds LC, Walker S, Rogers C, Mathur AM, Van Essen DC, Inder T. Alterations in brain structure and neurodevelopmental outcome in preterm infants hospitalized in different neonatal intensive care unit environments. J Pediatr. 2014 Jan; 164(1):52-60.e2.
  29. Crapnell TL, Rogers CE, Neil JJ, Inder TE, Woodward LJ, Pineda RG. Factors associated with feeding difficulties in the very preterm infant. Acta Paediatr. 2013 Dec; 102(12):e539-45.
  30. Zarem C, Kidokoro H, Neil J, Wallendorf M, Inder T, Pineda R. Psychometrics of the neonatal oral motor assessment scale. Dev Med Child Neurol. 2013 Dec; 55(12):1115-20.
  31. Smyser CD, Snyder AZ, Shimony JS, Blazey TM, Inder TE, Neil JJ. Effects of white matter injury on resting state fMRI measures in prematurely born infants. PLoS One. 2013; 8(7):e68098.
  32. Omizzolo C, Scratch SE, Stargatt R, Kidokoro H, Thompson DK, Lee KJ, Cheong J, Neil J, Inder TE, Doyle LW, Anderson PJ. Neonatal brain abnormalities and memory and learning outcomes at 7 years in children born very preterm. Memory. 2014; 22(6):605-15.
  33. Kidokoro H, Neil JJ, Inder TE. New MR imaging assessment tool to define brain abnormalities in very preterm infants at term. AJNR Am J Neuroradiol. 2013 Nov-Dec; 34(11):2208-14.
  34. Reynolds LC, Duncan MM, Smith GC, Mathur A, Neil J, Inder T, Pineda RG. Parental presence and holding in the neonatal intensive care unit and associations with early neurobehavior. J Perinatol. 2013 Aug; 33(8):636-41.
  35. Pineda RG, Castellano A, Rogers C, Neil JJ, Inder T. Factors associated with developmental concern and intent to access therapy following discharge from the NICU. Pediatr Phys Ther. 2013; 25(1):62-9.
  36. Pineda RG, Tjoeng TH, Vavasseur C, Kidokoro H, Neil JJ, Inder T. Patterns of altered neurobehavior in preterm infants within the neonatal intensive care unit. J Pediatr. 2013 Mar; 162(3):470-476.e1.
  37. Mitchell TJ, Neil JJ, Zempel JM, Thio LL, Inder TE, Bretthorst GL. Automating the analysis of EEG recordings from prematurely-born infants: a Bayesian approach. Clin Neurophysiol. 2013 Mar; 124(3):452-61.
  38. Bednarek N, Mathur A, Inder T, Wilkinson J, Neil J, Shimony J. Impact of therapeutic hypothermia on MRI diffusion changes in neonatal encephalopathy. Neurology. 2012 May 01; 78(18):1420-7.
  39. Rogers CE, Anderson PJ, Thompson DK, Kidokoro H, Wallendorf M, Treyvaud K, Roberts G, Doyle LW, Neil JJ, Inder TE. Regional cerebral development at term relates to school-age social-emotional development in very preterm children. J Am Acad Child Adolesc Psychiatry. 2012 Feb; 51(2):181-91.
  40. Griffith JL, Shimony JS, Cousins SA, Rees SE, McCurnin DC, Inder TE, Neil JJ. MR imaging correlates of white-matter pathology in a preterm baboon model. Pediatr Res. 2012 Feb; 71(2):185-91.
  41. Tao JD, Barnette AR, Griffith JL, Neil JJ, Inder TE. Histopathologic correlation with diffusion tensor imaging after chronic hypoxia in the immature ferret. Pediatr Res. 2012 Feb; 71(2):192-8.
  42. Ortinau C, Beca J, Lambeth J, Ferdman B, Alexopoulos D, Shimony JS, Wallendorf M, Neil J, Inder T. Regional alterations in cerebral growth exist preoperatively in infants with congenital heart disease. J Thorac Cardiovasc Surg. 2012 Jun; 143(6):1264-70.
  43. Pineda RG, Stransky KE, Rogers C, Duncan MH, Smith GC, Neil J, Inder T. The single-patient room in the NICU: maternal and family effects. J Perinatol. 2012 Jul; 32(7):545-51.
  44. Smith GC, Gutovich J, Smyser C, Pineda R, Newnham C, Tjoeng TH, Vavasseur C, Wallendorf M, Neil J, Inder T. Neonatal intensive care unit stress is associated with brain development in preterm infants. Ann Neurol. 2011 Oct; 70(4):541-9.
  45. Kidokoro H, Anderson PJ, Doyle LW, Neil JJ, Inder TE. High signal intensity on T2-weighted MR imaging at term-equivalent age in preterm infants does not predict 2-year neurodevelopmental outcomes. AJNR Am J Neuroradiol. 2011 Dec; 32(11):2005-10.
  46. Inder TE, Tao J, Neil JJ. Common lesions in the newborn brain. Top Magn Reson Imaging. 2011 Feb; 22(1):25-32.
  47. Hill J, Inder T, Neil J, Dierker D, Harwell J, Van Essen D. Similar patterns of cortical expansion during human development and evolution. Proc Natl Acad Sci U S A. 2010 Jul 20; 107(29):13135-40.
  48. Smyser CD, Inder TE, Shimony JS, Hill JE, Degnan AJ, Snyder AZ, Neil JJ. Longitudinal analysis of neural network development in preterm infants. Cereb Cortex. 2010 Dec; 20(12):2852-62.
  49. Hill J, Dierker D, Neil J, Inder T, Knutsen A, Harwell J, Coalson T, Van Essen D. A surface-based analysis of hemispheric asymmetries and folding of cerebral cortex in term-born human infants. J Neurosci. 2010 Feb 10; 30(6):2268-76.
  50. Mathur AM, Neil JJ, Inder TE. Understanding brain injury and neurodevelopmental disabilities in the preterm infant: the evolving role of advanced magnetic resonance imaging. Semin Perinatol. 2010 Feb; 34(1):57-66.
  51. Lodygensky GA, West T, Stump M, Holtzman DM, Inder TE, Neil JJ. In vivo MRI analysis of an inflammatory injury in the developing brain. Brain Behav Immun. 2010 Jul; 24(5):759-67.
  52. Neil J. Is MRI still cool after hypothermia? Lancet Neurol. 2010 Jan; 9(1):19-20.
  53. Shimony JS, Lawrence R, Neil JJ, Inder TE. Imaging for diagnosis and treatment of cerebral palsy. Clin Obstet Gynecol. 2008 Dec; 51(4):787-99.
  54. Mathur AM, Neil JJ, McKinstry RC, Inder TE. Transport, monitoring, and successful brain MR imaging in unsedated neonates. Pediatr Radiol. 2008 Mar; 38(3):260-4.
  55. Kroenke CD, Van Essen DC, Inder TE, Rees S, Bretthorst GL, Neil JJ. Microstructural changes of the baboon cerebral cortex during gestational development reflected in magnetic resonance imaging diffusion anisotropy. J Neurosci. 2007 Nov 14; 27(46):12506-15.
  56. Lodygensky GA, Inder TE, Neil JJ. Application of magnetic resonance imaging in animal models of perinatal hypoxic-ischemic cerebral injury. Int J Dev Neurosci. 2008 Feb; 26(1):13-25.
  57. Sizonenko SV, Camm EJ, Garbow JR, Maier SE, Inder TE, Williams CE, Neil JJ, Huppi PS. Developmental changes and injury induced disruption of the radial organization of the cortex in the immature rat brain revealed by in vivo diffusion tensor MRI. Cereb Cortex. 2007 Nov; 17(11):2609-17.
  58. Neil JJ, Inder TE. Detection of wallerian degeneration in a newborn by diffusion magnetic resonance imaging (MRI). J Child Neurol. 2006 Feb; 21(2):115-8.
  59. Kroenke CD, Bretthorst GL, Inder TE, Neil JJ. Modeling water diffusion anisotropy within fixed newborn primate brain using Bayesian probability theory. Magn Reson Med. 2006 Jan; 55(1):187-97.
  60. Inder T, Neil J, Yoder B, Rees S. Patterns of cerebral injury in a primate model of preterm birth and neonatal intensive care. J Child Neurol. 2005 Dec; 20(12):965-7.
  61. Kroenke CD, Bretthorst GL, Inder TE, Neil JJ. Diffusion MR imaging characteristics of the developing primate brain. Neuroimage. 2005 May 01; 25(4):1205-13.
  62. Cameron FJ, Kean MJ, Wellard RM, Werther GA, Neil JJ, Inder TE. Insights into the acute cerebral metabolic changes associated with childhood diabetes. Diabet Med. 2005 May; 22(5):648-53.
  63. Inder T, Neil J, Kroenke C, Dieni S, Yoder B, Rees S. Investigation of cerebral development and injury in the prematurely born primate by magnetic resonance imaging and histopathology. Dev Neurosci. 2005 Mar-Aug; 27(2-4):100-11.
  64. Inder T, Neil J, Yoder B, Rees S. Non-human primate models of neonatal brain injury. Semin Perinatol. 2004 Dec; 28(6):396-404.
  65. Neil JJ, Inder TE. Imaging perinatal brain injury in premature infants. Semin Perinatol. 2004 Dec; 28(6):433-43.
  66. Hunt RW, Neil JJ, Coleman LT, Kean MJ, Inder TE. Apparent diffusion coefficient in the posterior limb of the internal capsule predicts outcome after perinatal asphyxia. Pediatrics. 2004 Oct; 114(4):999-1003.
  67. Moinuddin A, McKinstry RC, Martin KA, Neil JJ. Intracranial hemorrhage progressing to porencephaly as a result of congenitally acquired cytomegalovirus infection--an illustrative report. Prenat Diagn. 2003 Oct; 23(10):797-800.
  68. Miller JH, McKinstry RC, Philip JV, Mukherjee P, Neil JJ. Diffusion-tensor MR imaging of normal brain maturation: a guide to structural development and myelination. AJR Am J Roentgenol. 2003 Mar; 180(3):851-9.
  69. McKinstry RC, Miller JH, Snyder AZ, Mathur A, Schefft GL, Almli CR, Shimony JS, Shiran SI, Neil JJ. A prospective, longitudinal diffusion tensor imaging study of brain injury in newborns. Neurology. 2002 Sep 24; 59(6):824-33.
  70. Gauvain KM, McKinstry RC, Mukherjee P, Perry A, Neil JJ, Kaufman BA, Hayashi RJ. Evaluating pediatric brain tumor cellularity with diffusion-tensor imaging. AJR Am J Roentgenol. 2001 Aug; 177(2):449-54.
  71. Neil JJ. Functional imaging of the central nervous system using magnetic resonance imaging and positron emission tomography. Curr Opin Neurol. 1993 Dec; 6(6):927-33.
To schedule an appointment: Call 617-355-8994 or Request an Appointment

Locations

Boston Children’s is so much more than a hospital—it’s a community of researchers, clinicians, administrators, support staff, innovators, teachers, patients and families, all working together to make the impossible possible. ”
- Sandra L. Fenwick, President and CEO

Boston Children's Hospital
300 Longwood Avenue, Boston, MA 02115
For Patients: 617-355-6000
For Referring Providers: 844-BCH-PEDS | 844-224-7337

Close