EDUCATION

Graduate Degree

MPH
  • Harvard School of Public Health , Boston , MA

Medical School

  • Northwestern University Medical School , Chicago , IL

Internship

  • Boston Children's Hospital , Boston , MA

Residency

Pediatrics
  • Boston Children's Hospital , Boston , MA

Residency

Anaesthesia
  • Massachusetts General Hospital , Boston , MA

Fellowship

Pediatric Anesthesia Critical Care
  • Boston Children's Hospital , Boston , MA

CERTIFICATIONS

  • American Board of Anesthesiology, Pediatric Anesthesiology
  • American Board of Anesthesiology, Critical Care Medicine

PUBLICATIONS

Publications powered by Harvard Catalyst Profiles

  1. Graham RJ, McManus ML, Rodday AM, Weidner RA, Parsons SK. Pediatric Specialty Care Model for Management of Chronic Respiratory Failure: Cost and Savings Implications and Misalignment With Payment Models. Pediatr Crit Care Med. 2018 May; 19(5):412-420. View abstract
  2. França UL, McManus ML. Frequency, trends, and antecedents of severe maternal depression after three million U.S. births. PLoS One. 2018; 13(2):e0192854. View abstract
  3. França UL, McManus ML. Trends in Regionalization of Hospital Care for Common Pediatric Conditions. Pediatrics. 2018 Jan; 141(1). View abstract
  4. França UL, McManus ML. Availability of Definitive Hospital Care for Children. JAMA Pediatr. 2017 Sep 05; 171(9):e171096. View abstract
  5. Shkirkova K, Akam EY, Huang J, Sheth SA, Nour M, Liang CW, McManus M, Trinh V, Duckwiler G, Tarpley J, Vinuela F, Saver JL. Feasibility and utility of an integrated medical imaging and informatics smartphone system for management of acute stroke. Int J Stroke. 2017 12; 12(9):953-960. View abstract
  6. França UL, McManus ML. Transfer Frequency as a Measure of Hospital Capability and Regionalization. Health Serv Res. 2017 12; 52(6):2237-2255. View abstract
  7. Graham RJ, McManus ML, Rodday AM, Weidner RA, Parsons SK. Chronic respiratory failure: Utilization of a pediatric specialty integrated care program. Healthc (Amst). 2017 Mar; 5(1-2):23-28. View abstract
  8. McManus ML. Shifting Goals in Operating Room Management. A A Case Rep. 2016 Mar 15; 6(6):181-2. View abstract
  9. França UL, Mustafa S, McManus ML. The Growing Burden of Neonatal Opiate Exposure on Children and Family Services in Massachusetts. Child Maltreat. 2016 Feb; 21(1):80-4. View abstract
  10. Bravo F, Levi R, Ferrari LR, McManus ML. The nature and sources of variability in pediatric surgical case duration. Paediatr Anaesth. 2015 Oct; 25(10):999-1006. View abstract
  11. Casavant DW, McManus ML, Parsons SK, Zurakowski D, Graham RJ. Trial of telemedicine for patients on home ventilator support: feasibility, confidence in clinical management and use in medical decision-making. J Telemed Telecare. 2014 Dec; 20(8):441-9. View abstract
  12. Mir-Kasimov M, Sturrock A, McManus M, Paine R. Effect of alveolar epithelial cell plasticity on the regulation of GM-CSF expression. Am J Physiol Lung Cell Mol Physiol. 2012 Mar 15; 302(6):L504-11. View abstract
  13. Sturrock A, Seedahmed E, Mir-Kasimov M, Boltax J, McManus ML, Paine R. GM-CSF provides autocrine protection for murine alveolar epithelial cells from oxidant-induced mitochondrial injury. Am J Physiol Lung Cell Mol Physiol. 2012 Feb 01; 302(3):L343-51. View abstract
  14. Solter LF, Pilarska DK, McManus ML, Zúbrik M, Patocka J, Huang WF, Novotný J. Host specificity of microsporidia pathogenic to the gypsy moth, Lymantria dispar (L.): field studies in Slovakia. J Invertebr Pathol. 2010 Sep; 105(1):1-10. View abstract
  15. Kheir JN, Lawlor MW, Ahn ES, Lehmann L, Riviello JJ, Silvera VM, McManus M, Folkerth RD. Neuropathology of a fatal case of posterior reversible encephalopathy syndrome. Pediatr Dev Pathol. 2010 Sep-Oct; 13(5):397-403. View abstract
  16. Sturrock A, Vollbrecht T, Mir-Kasimov M, McManus M, Wilcoxen SE, Paine R. Mechanisms of suppression of alveolar epithelial cell GM-CSF expression in the setting of hyperoxic stress. Am J Physiol Lung Cell Mol Physiol. 2010 Mar; 298(3):L446-53. View abstract
  17. Hoch G, D'Amico V, Solter LF, Zubrik M, McManus ML. Quantifying horizontal transmission of Nosema lymantriae, a microsporidian pathogen of the gypsy moth, Lymantria dispar (Lep., Lymantriidae) in field cage studies. J Invertebr Pathol. 2008 Oct; 99(2):146-50. View abstract
  18. Vinecore K, Aboy M, McNames J, Phillips C, Agbeko R, Peters M, Ellenby M, McManus ML, Goldstein B. Design and implementation of a portable physiologic data acquisition system. Pediatr Crit Care Med. 2007 Nov; 8(6):563-9. View abstract
  19. Wolf GK, McClain CD, Zurakowski D, Dodson B, McManus ML. Total phenytoin concentrations do not accurately predict free phenytoin concentrations in critically ill children. Pediatr Crit Care Med. 2006 Sep; 7(5):434-9; quiz 440. View abstract
  20. Vavra J, Hylis M, Vossbrinck CR, Pilarska DK, Linde A, Weiser J, McManus ML, Hoch G, Solter LF. Vairimorpha disparis n. comb. (Microsporidia: Burenellidae): a redescription and taxonomic revision of Thelohania disparis Timofejeva 1956, a microsporidian parasite of the gypsy moth Lymantria dispar (L.) (Lepidoptera: Lymantriidae). J Eukaryot Microbiol. 2006 Jul-Aug; 53(4):292-304. View abstract
  21. Fallon DJ, Solter LF, Bauer LS, Miller DL, Cate JR, McManus ML. Effect of entomopathogenic nematodes on Plectrodera scalator (Fabricius) (Coleoptera: Cerambycidae). J Invertebr Pathol. 2006 May; 92(1):55-7. View abstract
  22. Hylis M, Pilarska DK, Oborník M, Vávra J, Solter LF, Weiser J, Linde A, McManus ML. Nosema chrysorrhoeae n. sp. (Microsporidia), isolated from browntail moth (Euproctis chrysorrhoea L.) (Lepidoptera, Lymantriidae) in Bulgaria: characterization and phylogenetic relationships. J Invertebr Pathol. 2006 Feb; 91(2):105-14. View abstract
  23. Litvak E, Buerhaus PI, Davidoff F, Long MC, McManus ML, Berwick DM. Managing unnecessary variability in patient demand to reduce nursing stress and improve patient safety. Jt Comm J Qual Patient Saf. 2005 Jun; 31(6):330-8. View abstract
  24. Khwaja OS, Robson CD, McManus ML, Urion DK. Basilar meningitis associated with ethmoid and sphenoid cephaloceles. Pediatr Neurol. 2005 Jul; 33(1):57-60. View abstract
  25. Wise-Faberowski L, Soriano SG, Ferrari L, McManus ML, Wolfsdorf JI, Majzoub J, Scott RM, Truog R, Rockoff MA. Perioperative management of diabetes insipidus in children. J Neurosurg Anesthesiol. 2004 Jul; 16(3):220-5. View abstract
  26. McManus ML, Long MC, Cooper A, Litvak E. Queuing theory accurately models the need for critical care resources. Anesthesiology. 2004 May; 100(5):1271-6. View abstract
  27. Wise-Faberowski L, Soriano SG, Ferrari L, McManus ML, Wolfsdorf JI, Majzoub J, Scott RM, Truog R, Rockoff MA. Perioperative management of diabetes insipidus in children [corrected]. J Neurosurg Anesthesiol. 2004 Jan; 16(1):14-9. View abstract
  28. McManus ML, Long MC, Cooper A, Mandell J, Berwick DM, Pagano M, Litvak E. Variability in surgical caseload and access to intensive care services. Anesthesiology. 2003 Jun; 98(6):1491-6. View abstract
  29. Litvak E, Long MC, Cooper AB, McManus ML. Emergency department diversion: causes and solutions. Acad Emerg Med. 2001 Nov; 8(11):1108-10. View abstract
  30. D'Amico V, Elkinton JS, Podgwaite JD, Slavicek JM, McManus ML, Burand JP. A field release of genetically engineered gypsy moth (Lymantria dispar L.) nuclear polyhedrosis virus (LdNPV). J Invertebr Pathol. 1999 May; 73(3):260-8. View abstract
  31. Bauer LS, Miller DL, Maddox JV, McManus ML. Interactions between a Nosema sp. (Microspora: nosematidae) and nuclear polyhedrosis virus infecting the gypsy moth, Lymantria dispar (Lepidoptera: lymantriidae). J Invertebr Pathol. 1998 Sep; 72(2):147-53. View abstract
  32. McManus ML, Soriano SG. Rebound swelling of astroglial cells exposed to hypertonic mannitol. Anesthesiology. 1998 Jun; 88(6):1586-91. View abstract
  33. Emma F, McManus M, Strange K. Intracellular electrolytes regulate the volume set point of the organic osmolyte/anion channel VSOAC. Am J Physiol. 1997 Jun; 272(6 Pt 1):C1766-75. View abstract
  34. Soriano SG, McManus ML, Sullivan LJ, Rockoff MA, Black PM, Burrows FA. Cerebral blood flow velocity after mannitol infusion in children. Can J Anaesth. 1996 May; 43(5 Pt 1):461-6. View abstract
  35. McManus ML, Churchwell KB, Strange K. Regulation of cell volume in health and disease. N Engl J Med. 1995 Nov 09; 333(19):1260-6. View abstract
  36. McManus ML, Kevy SV, Bower LK, Hickey PR. Coagulation factor deficiencies during initiation of extracorporeal membrane oxygenation. J Pediatr. 1995 Jun; 126(6):900-4. View abstract
  37. Churchwell KB, McManus ML, Kent P, Gorlin J, Galacki D, Humphreys D, Kevy SV. Intensive blood and plasma exchange for treatment of coagulopathy in meningococcemia. J Clin Apher. 1995; 10(4):171-7. View abstract
  38. Soriano SG, McManus ML, Sullivan LJ, Scott RM, Rockoff MA. Doppler sensor placement during neurosurgical procedures for children in the prone position. J Neurosurg Anesthesiol. 1994 Jul; 6(3):153-5. View abstract
  39. McManus M, Serhan C, Jackson P, Strange K. Ketoconazole blocks organic osmolyte efflux independently of its effect on arachidonic acid conversion. Am J Physiol. 1994 Jul; 267(1 Pt 1):C266-71. View abstract
  40. McManus M, Fischbarg J, Sun A, Hebert S, Strange K. Laser light-scattering system for studying cell volume regulation and membrane transport processes. Am J Physiol. 1993 Aug; 265(2 Pt 1):C562-70. View abstract
  41. McManus ML, Strange K. Acute volume regulation of brain cells in response to hypertonic challenge. Anesthesiology. 1993 Jun; 78(6):1132-7. View abstract
  42. McManus ML, Churchwell KB. Coagulopathy as a predictor of outcome in meningococcal sepsis and the systemic inflammatory response syndrome with purpura. Crit Care Med. 1993 May; 21(5):706-11. View abstract
  43. Paredes A, McManus M, Kwon HM, Strange K. Osmoregulation of Na(+)-inositol cotransporter activity and mRNA levels in brain glial cells. Am J Physiol. 1992 Dec; 263(6 Pt 1):C1282-8. View abstract
  44. Irazuzta J, McManus ML. Use of topically applied nitroglycerin in the treatment of purpura fulminans. J Pediatr. 1990 Dec; 117(6):993-5. View abstract