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Grace M Lee
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Grace M.  Lee, MD, MPH

Department: Medicine
Research Centers: Infectious Diseases Research Center
Hospital Title: Senior Associate Physician in Medicine; Associate Medical Director, Infection Control
Academic Title: Associate Professor of Population Medicine and Pediatrics, Harvard Medical School
Research Area: Vaccine policy
Infectious disease epidemiology

Research Overview

Dr. Lee's research focuses on vaccine economics, vaccine safety, infectious disease epidemiology and infection control and prevention. She is current principal investigator or co-investigator on AHRQ, NIH, HHS and CDC-funded studies. Dr. Lee leads several key research projects that include: monitoring H1N1 and seasonal influenza vaccine safety in near real-time for the Vaccine Safety Datalink and Post-Licensure Rapid Immunization Safety Monitoring systems, describing the influenza vaccine financing and delivery system in the U.S., examining the impact of pneumococcal conjugate vaccination on carriage, disease and population genetics in young children, conducting cost-effectiveness analyses of interventions to prevent healthcare-associated infections (HAIs), and evaluating the health and economic impact of Medicare’s policy of nonpayment for HAIs. She is currently enrolling hospitals in the AHRQ-funded Preventing Avoidable Infectious Complications by Adjusting Payment (PAICAP) study.

About Grace Lee

Grace Lee, MD, MPH is an Associate Professor of Pediatrics in the Division of Infectious Diseases, Department of Medicine and Department of Laboratory Medicine at Boston Children's Hospital. Dr. Lee is also an Associate Professor in the Department of Population Medicine (DPM) at Harvard Medical School and Harvard Pilgrim Health Care Institute. She is a member of the Center for Child Health Care Studies at DPM.

Dr. Lee joined the Division of Infectious Diseases at Boston Children's Hospital and DPM at Harvard Medical School and Harvard Pilgrim Health Care Institute in 2003 after completing an Agency for Healthcare Research and Quality post-doctoral fellowship. She received her MD at the University of Pennsylvania School of Medicine and Master of Public Health at Harvard School of Public Health. She completed her pediatric residency and subspecialty training in Pediatric Infectious Diseases and Pediatrics Health Services Research at Boston Children's Hospital.

Key Publications

  • Lee GM, Harper MB. Risk of bacteremia for febrile young children in the post-Haemophilus influenzae Type b era. Arch Pediatr Adolesc Med 1998;152:624-628.

  • Lee GM, Fleisher GR, Harper MB. Management of febrile children in the age of the conjugate pneumococcal vaccine: A cost-effectiveness analysis. Pediatrics 2001; 108: 835-844.

  • Lee GM, Lett S, Schauer S, LeBaron CW, Murphy TV, Rusinak D, Lieu TA, for the Massachusetts Pertussis Study Group. Societal costs and morbidity of pertussis in adolescents and adults. Clinical Infectious Diseases 2004; 39:1572-1580.

  • Lee GM, Salomon JA, Friedman JF, Hibberd PL, Ross-Degnan D, Zasloff E, Bediako S, Goldmann DA. Illness Transmission in the Home: A Possible Role for Alcohol-Based Hand Gels. Pediatrics 2005; 115:852-860.

  • Lee GM, LeBaron CW, Murphy TV, Lett S, Schauer S, Lieu TA. Pertussis among adolescents and adults: Should we vaccinate? Pediatrics 2005; 115:1675-1684.

  • Lee GM, Gortmaker SL, McIntosh K, Hughes MD, Oleske JM, for the PACTG 219C Team. Quality of Life in HIV-Infected Children. Pediatrics,2006; 117:273-83.

  • Lee GM, Murphy TV, Lett S, Cortese MM, Kretsinger K, Schauer S, Lieu TA. Cost-effectiveness of Pertussis Vaccination in Adults. Am J Prev Med 2007; 32(3):186-193.

  • Lee GM, Santoli JM, Hannan C, Messonier ML, Sabin JE, Rusinak D, Gay C, Lett SM, Lieu TA. Gaps in Vaccine Financing for Underinsured Children in the United States. JAMA, 2007; 298(6): 638-643.

  • Pfoh E, Wessels MR, Goldmann DA, Lee GM. Burden and Economic Cost of Group A Streptococcal Pharyngitis. Pediatrics, 2008; 121:229-234.

  • Lee GM, Lorick S, Pfoh E, Kleinman K, Fishbein D. Adolescent Immunizations: Missed Opportunities for Prevention. Pediatrics, 2008; 122 (4): 711-7.

  • Nakamura MM, Lee GM. Influenza Vaccination in Adolescents with High-Risk Conditions. Pediatrics, 2008; 122 (5): 920-8.

  • Sandora TJ, Pfoh E, Lee GM. Adverse events after Tdap vaccine in healthcare workers. Infection Control and Hospital Epidemiology, 2009; 30(4):389-9.

  • Lee GM, Huang SS, Rifas-Shiman SL, Hinrichsen VL, Pelton SI, Kleinman K, Hanage WP, Lipsitch M, McAdam AJ, Finkelstein JA. Staphylococcus aureus colonization in children from 2003-2007. BMC Infectious Diseases, 2009; 9:110.

  • Sandora TJ, Smole SC, Lee GM, Chung S, Williams L, McAdam AJ. Test characteristics of commercial influenza assays for detecting pandemic influenza A (H1N1) in children. Pediatr Infect Dis J. 2009 Nov 20.

  • Greene SK, Kulldorff M, Lewis EM, Li R, Yin R, Weintraub ES, Fireman BF, Lieu TA, Nordin JD, Glanz JM, Baxter R, Jacobsen SJ, Broder KR, Lee GM. Near Real-Time Surveillance for Influenza Vaccine Safety: Proof-of-concept in the Vaccine Safety Datalink Project. Am J Epidemiol, 2010; 171(2):177-188.
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