James E.  Lock

James Lock, MD

Cardiologist-in-Chief Emeritus and Chairman of the Department of Cardiology

Alexander S. Nadas Professor of Pediatrics, Harvard Medical School

Medical Services


  • Interventional Catheterization
  • Cardiology


  • Cardiology
  • Cardiovascular Program


  • Cardiac Catheterization Labs
  • Fetal Cardiology Program
To schedule an appointment: Call 617-355-7313 or Request an Appointment

Experience and Education


Undergraduate Degree

Case Western Reserve University, 1969

Cleveland, OH

Medical School

Stanford University School of Medicine, 1973

Stanford, CA


University of Minnesota Hospital & Clinics, 1973-1974

Minneapolis, MN


University of Minnesota Hospital & Clinics, 1974-1975

Minneapolis, MN


Hospital for Sick Children, 1977-1979

Toronto, CANADA


  • Pediatrics, Pediatric Cardiology

Professional History

Dr. James Lock is Cardiologist-in-Chief and Chairman of the Department of Cardiology at Boston Children’s Hospital, and the Alexander S. Nadas Professor of Pediatrics at Harvard Medical School.  Dr. Lock attended medical school at Stanford University, pursued pediatric residency and cardiology fellowship at the University of Minnesota, and trained in cardiovascular physiology for two years at the University of Toronto, Hospital for Sick Children.  Scientific work on pulmonary vascular control was supported by an AHA Established Investigator Award, the March of Dimes (Basil O’Connor Award) and National Institutes of Health (RO1 HL).  Dr. Lock shifted his research focus to experimental interventional cardiology, providing most of the basic research in that field.  In 1984, he joined Boston Children’s Hospital as Director of the Cardiac Catheterization Laboratory, and became Department Chair in 1993.

Dr. Lock has invented several cardiac catheterization devices and has developed several dozen new non-surgical procedures to improve care for children with complex heart disease.  In September 1999, the CardioSEAL device developed by Dr. Lock and others became the first septal occlusion device to receive FDA approval for use inside the human heart.  He has authored or co-authored 250 peer-reviewed scientific papers.  He is the president of Boston Children’s Heart Foundation, the president of the Aldo Castaneda Foundation, and serves on the Finance Committee Board of Directors of Boston Children’s Hospital.

During his research career, Dr. Lock has trained nearly a hundred academic physicians in cardiopulmonary physiology, experimental interventional cardiology and clinical interventional cardiology.  Beginning five years ago, he and his colleagues started a highly innovative program to standardize clinical care in a fashion that improves outcomes, reduces unnecessary utilization and supports innovation. That program, termed SCAMPs, is now rapidly gaining acceptance throughout the medical community.

To schedule an appointment: Call 617-355-7313 or Request an Appointment


The future of pediatrics will be forged by thinking differently, breaking paradigms and joining together in a shared vision of tackling the toughest challenges before us.”
- Sandra L. Fenwick, President and CEO

Boston Children's Hospital 300 Longwood Avenue, Boston, MA 02115 617-355-6000 | 800-355-7944