Thomas Hamilton

Thomas Hamilton, MD

Assistant Program Director, Pediatric Surgery Fellowship Program; Attending Surgeon, Esophageal Atresia Treatment Program

Assistant Professor of Surgery, Harvard Medical School

  • Contact: 617-355-7800

  • Fax: 617-730-0477

Medical Services

Specialties

  • General Surgery
  • Surgical Oncology
  • Neonatal Surgery
  • Thoracic Surgery
  • Circumcision
  • Undescended Testicles

Departments

  • Surgery

Programs

  • Esophageal and Airway Treatment Center
  • Surgery Program
To schedule an appointment: Call 617-355-7800 or Request an Appointment

Experience and Education

Education

Undergraduate

Bowdoin College, 1986

Medical School

Cornell University Medical College, 1991

Fellowship, Pediatric Surgery

Boston Children's Hospital, 1998-2000

Boston, MA

Internship, General Surgery

Hospital of the University of Pennsylvania , 1991-1992

Residency, General Surgery

Hospital of the University of Pennsylvania , 1992-1998

Certifications

  • General Surgery, Pediatric Surgery

Publications

Publications powered by Harvard Catalyst Profiles
  1. Bairdain S, Foker JE, Smithers CJ, Hamilton TE, Labow BI, Baird CW, Taghinia AH, Feins N, Manfredi M, Jennings RW. Jejunal Interposition after Failed Esophageal Atresia Repair. J Am Coll Surg. 2016 Jun; 222(6):1001-8.
  2. Dionigi B, Bairdain S, Smithers CJ, Jennings RW, Hamilton TE. Restoring esophageal continuity following a failed colonic interposition for long-gap esophageal atresia. J Surg Case Rep. 2015; 2015(4).
  3. Bairdain S, Hamilton TE, Smithers CJ, Manfredi M, Ngo P, Gallagher D, Zurakowski D, Foker JE, Jennings RW. Foker process for the correction of long gap esophageal atresia: Primary treatment versus secondary treatment after prior esophageal surgery. J Pediatr Surg. 2015 Jun; 50(6):933-7.
  4. Bairdain S, Smithers CJ, Hamilton TE, Zurakowski D, Rhein L, Foker JE, Baird C, Jennings RW. Direct tracheobronchopexy to correct airway collapse due to severe tracheobronchomalacia: Short-term outcomes in a series of 20 patients. J Pediatr Surg. 2015 Jun; 50(6):972-7.
  5. Manfredi MA, Jennings RW, Anjum MW, Hamilton TE, Smithers CJ, Lightdale JR. Externally removable stents in the treatment of benign recalcitrant strictures and esophageal perforations in pediatric patients with esophageal atresia. Gastrointest Endosc. 2014 Aug; 80(2):246-52.
  6. Jennings RW, Hamilton TE, Smithers CJ, Ngerncham M, Feins N, Foker JE. Surgical approaches to aortopexy for severe tracheomalacia. J Pediatr Surg. 2014 Jan; 49(1):66-70; discussion 70-1.
  7. Hamilton TE, Barnhart D, Gow K, Ferrer F, Kandel J, Glick R, Dasgupta R, Naranjo A, He Y, Gratias E, Geller J, Mullen E, Ehrlich P. Inter-rater reliability of surgical reviews for AREN03B2: a COG renal tumor committee study. J Pediatr Surg. 2014 Jan; 49(1):154-8; discussion 158.
  8. Hamilton TE. Regulatory oversight in transplantation: are the patients really better off? Curr Opin Organ Transplant. 2013 Apr; 18(2):203-9.
  9. Gow KW, Barnhart DC, Hamilton TE, Kandel JJ, Chen MK, Ferrer FA, Price MR, Mullen EA, Geller JI, Gratias EJ, Rosen N, Khanna G, Naranjo A, Ritchey ML, Grundy PE, Dome JS, Ehrlich PF. Primary nephrectomy and intraoperative tumor spill: report from the Children's Oncology Group (COG) renal tumors committee. J Pediatr Surg. 2013 Jan; 48(1):34-8.
  10. Hamilton TE, Shamberger RC. Wilms tumor: recent advances in clinical care and biology. Semin Pediatr Surg. 2012 Feb; 21(1):15-20.
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  12. Hamilton TE, Ritchey ML, Haase GM, Argani P, Peterson SM, Anderson JR, Green DM, Shamberger RC. The management of synchronous bilateral Wilms tumor: a report from the National Wilms Tumor Study Group. Ann Surg. 2011 May; 253(5):1004-10.
  13. Hamilton TE. Accountability in health care--transplant community offers leadership. Am J Transplant. 2009 Jun; 9(6):1287-93.
  14. Liang S, Yang N, Pan Y, Deng S, Lin X, Yang X, Katsaros D, Roby KF, Hamilton TC, Connolly DC, Coukos G, Zhang L. Expression of activated PIK3CA in ovarian surface epithelium results in hyperplasia but not tumor formation. PLoS One. 2009; 4(1):e4295.
  15. Hamilton TE, Ritchey ML, Argani P, Beckwith JB, Perlman EJ, Cotton CA, Shamberger RC. Synchronous bilateral Wilm's tumor with complete radiographic response managed without surgical resection: a report from the National Wilm's Tumor Study 4. J Pediatr Surg. 2008 Nov; 43(11):1982-4.
  16. Hamilton TE. Improving organ transplantation in the United States--a regulatory perspective. Am J Transplant. 2008 Dec; 8(12):2503-5.
  17. Ritchey M, Daley S, Shamberger RC, Ehrlich P, Hamilton T, Haase G, Sawin R. Ureteral extension in Wilms' tumor: a report from the National Wilms' Tumor Study Group (NWTSG). J Pediatr Surg. 2008 Sep; 43(9):1625-9.
  18. Hamilton TE, Davis S, Onstad L, Kopecky KJ. Thyrotropin levels in a population with no clinical, autoantibody, or ultrasonographic evidence of thyroid disease: implications for the diagnosis of subclinical hypothyroidism. J Clin Endocrinol Metab. 2008 Apr; 93(4):1224-30.
  19. Davis S, Onstad L, Kopecky KJ, Wiggins C, Hamilton TE. Locating members of a cohort identified retrospectively from limited data in 50-year-old records: successful approaches employed by the Hanford Thyroid Disease Study. Ann Epidemiol. 2008 Mar; 18(3):187-95.
  20. Hensley H, Quinn BA, Wolf RL, Litwin SL, Mabuchi S, Williams SJ, Williams C, Hamilton TC, Connolly DC. Magnetic resonance imaging for detection and determination of tumor volume in a genetically engineered mouse model of ovarian cancer. Cancer Biol Ther. 2007 Nov; 6(11):1717-25.
  21. Ritchey M, Daley S, Shamberger RC, Ehrlich P, Hamilton T, Haase G, Sawin R. Ureteral Extension In Wilms Tumor: A Report from the National Wilms Tumor Study Group (NWTSG). 2007; (In Press).
  22. Hamilton TE, Green DM, Perlman EJ, Argani P, Grundy P, Ritchey ML, Shamberger RC. Bilateral Wilms' tumor with anaplasia: lessons from the National Wilms' Tumor Study. J Pediatr Surg. 2006 Oct; 41(10):1641-4.
  23. Wax JR, Hamilton T, Cartin A, Dudley J, Pinette MG, Blackstone J. Congenital jejunal and ileal atresia: natural prenatal sonographic history and association with neonatal outcome. J Ultrasound Med. 2006 Mar; 25(3):337-42.
  24. Ehrlich PF, Hamilton TE, Grundy P, Ritchey M, Haase G, Shamberger RC. The value of surgery in directing therapy for patients with Wilms' tumor with pulmonary disease. A report from the National Wilms' Tumor Study Group (National Wilms' Tumor Study 5). J Pediatr Surg. 2006 Jan; 41(1):162-7; discussion 162-7.
  25. Mandal P, Novotny M, Hamilton TA. Lipopolysaccharide induces formyl peptide receptor 1 gene expression in macrophages and neutrophils via transcriptional and posttranscriptional mechanisms. J Immunol. 2005 Nov 1; 175(9):6085-91.
  26. Hamilton TE, Davis S, Onstad L, Kopecky KJ. Hyperparathyroidism in persons exposed to iodine-131 from the Hanford Nuclear Site. J Clin Endocrinol Metab. 2005 Dec; 90(12):6545-8.
  27. Ritchey ML, Shamberger RC, Hamilton T, Haase G, Argani P, Peterson S. Fate of bilateral renal lesions missed on preoperative imaging: a report from the National Wilms Tumor Study Group. J Urol. 2005 Oct; 174(4 Pt 2):1519-21; discussion 1521.
  28. Kopecky KJ, Onstad L, Hamilton TE, Davis S. Thyroid ultrasound abnormalities in persons exposed during childhood to 131I from the Hanford nuclear site. Thyroid. 2005 Jun; 15(6):604-13.
  29. Ehrlich PF, Ritchey ML, Hamilton TE, Haase GM, Ou S, Breslow N, Grundy P, Green D, Norkool P, Becker J, Shamberger RC. Quality assessment for Wilms' tumor: a report from the National Wilms' Tumor Study-5. J Pediatr Surg. 2005 Jan; 40(1):208-12; discussion 212-3.
  30. Hamilton TE, Rombeau JL. Nutritional Support. Fazio VW, Church JM, Delaney CP, editors. Current Therapy in Colon and Rectal Surgery. 2005.
  31. Davis S, Kopecky KJ, Hamilton TE, Onstad L. Thyroid neoplasia, autoimmune thyroiditis, and hypothyroidism in persons exposed to iodine 131 from the hanford nuclear site. JAMA. 2004 Dec 1; 292(21):2600-13.
  32. Kopecky KJ, Davis S, Hamilton TE, Saporito MS, Onstad LE. Estimation of thyroid radiation doses for the hanford thyroid disease study: results and implications for statistical power of the epidemiological analyses. Health Phys. 2004 Jul; 87(1):15-32.
  33. Pai RK, Convery M, Hamilton TA, Boom WH, Harding CV. Inhibition of IFN-gamma-induced class II transactivator expression by a 19-kDa lipoprotein from Mycobacterium tuberculosis: a potential mechanism for immune evasion. J Immunol. 2003 Jul 1; 171(1):175-84.
  34. Toshchakov V, Jones BW, Lentschat A, Silva A, Perera PY, Thomas K, Cody MJ, Zhang S, Williams BR, Major J, Hamilton TA, Fenton MJ, Vogel SN. TLR2 and TLR4 agonists stimulate unique repertoires of host resistance genes in murine macrophages: interferon-beta-dependent signaling in TLR4-mediated responses. J Endotoxin Res. 2003; 9(3):169-75.
  35. Hamilton TE. Open biopsy is superior to needle for detecting anaplasia in bilateral wilms tumor. 35th Annual Meeting of the American Pediatric Surgical Association, Ponte Vedra, FL. 2003.
  36. Pan B, Yao KS, Monia BP, Dean NM, McKay RA, Hamilton TC, O'Dwyer PJ. Reversal of cisplatin resistance in human ovarian cancer cell lines by a c-jun antisense oligodeoxynucleotide (ISIS 10582): evidence for the role of transcription factor overexpression in determining resistant phenotype. Biochem Pharmacol. 2002 May 1; 63(9):1699-707.
  37. Toshchakov V, Jones BW, Perera PY, Thomas K, Cody MJ, Zhang S, Williams BR, Major J, Hamilton TA, Fenton MJ, Vogel SN. TLR4, but not TLR2, mediates IFN-beta-induced STAT1alpha/beta-dependent gene expression in macrophages. Nat Immunol. 2002 Apr; 3(4):392-8.
  38. Wan XS, Hamilton TC, Ware JH, Donahue JJ, Kennedy AR. Growth inhibition and cytotoxicity induced by Bowman-Birk inhibitor concentrate in cisplatin-resistant human ovarian cancer cells. Nutr Cancer. 1998; 31(1):8-17.
  39. Hamilton TE, McClane SJ, Baldwin S, Burke C, Patel H, Rombeau JL, Raper SE. Efficient adenoviral-mediated murine neonatal small intestinal gene transfer is dependent on alpha(v) integrin expression. J Pediatr Surg. 1997 Dec; 32(12):1695-703.
  40. McClane SJ, Hamilton TE, DeMatteo RP, Burke C, Raper SE. Effect of adenoviral early genes and the host immune system on in vivo pancreatic gene transfer in the mouse. Pancreas. 1997 Oct; 15(3):236-45.
  41. McClane SJ, Hamilton TE, Burke CV, Raper SE. Functional consequences of adenovirus-mediated murine pancreatic gene transfer. Hum Gene Ther. 1997 Apr 10; 8(6):739-46.
  42. Hamilton T, DeMatteo R, McClane S, Burke C, Rombeau J, Raper S. Adenoviral-mediated gene transfer to murine small intestine is more efficient in neonates than adults. J Pediatr Surg. 1997 Feb; 32(2):373-7.
  43. McClane SJ, DeMatteo RP, Hamilton T, Burke C, Raper SE. Immunosuppressive effect on pancreatic trangene expression with recombinant adenovirus. International Gene Therapy Symposium, Cold Spring Harbor, NY. 1997.
  44. Hamilton TE, Koide S, Zhang W, Rombeau JL, Raper SE. Adenoviral-mediated gene transfer to the small intestinal isograft. Transplant Proc. 1996 Oct; 28(5):2444.
  45. Hamilton TE, DeMatteo RP, McClane SJ, Burke C, Rombeau JL, Raper SE. Adenoviral- mediated gene transfer to murine small intestine is more efficient in neonates than adults. Twenty-Seventh Annual Meeting of the American Pediatric Surgical Association, San Diego, CA. 1996.
  46. Hamilton TE, Rombeau JL. Enteral Nutrition. Nyhus LM, Baker RJ, Fischer JE, editors. Mastery of Surgery. 1996.
  47. McClane SJ, DeMatteo RP, Hamilton T, Burke C, Raper SE. Gene transfer to the mouse pancreas using adenovirus with deletions in various early genes. Gastroenterology. 1996; 110(4).
  48. Adamson WT, Hamilton TE, Shin D, Sharon M, Rornbeau JL. IGF-l and EGF enhance strength of intestinal anastomosis after bowel resection. 16th Annual Pediatric Surgical Resident's Conference, Oklahoma City, OK. 1995.
  49. Hamilton TE, DeMatteo RP, Rombeau JL, Raper SE. A comparison of adenoviral and retroviral gene transfer into the small intestine. Surg Forum. 1995; 649-650.
  50. Lew JI, Hamilton TE, Rombeau JL. The scientific-rationale and clinical utility of enteral nutritional therapy. Akttuelle Ernahrungsmedizin. 1995; Sonderheft 2:Band 20.
  51. Ko W, Zelano J, Lazenby W, Hamilton T, Isom 0, Krieger K . Optimal storage period for extended heart preservation with the University of Wisconsin solution. The J CardiovascV Surg. 1992; 33(2):2204-2210.
  52. Ko W, Zelano J, Lazzaro R, Lazenby W, Hamilton T, Isom 0, Krieger K. Superiority of the University of Wisconsin solution over simple crystalloid for extended heart preservation. J Thorac Cardiovas Surg. 1992; 103(5):980-982.
  53. Hamilton TE, van Belle G, LoGerfo JP. Thyroid neoplasia in Marshall Islanders exposed to nuclear fallout. JAMA. 1987 Aug 7; 258(5):629-35.
To schedule an appointment: Call 617-355-7800 or Request an Appointment

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