EDUCATION

Medical School

  • Harvard Medical School , Boston , MA

Graduate Degree

  • Children's Hospital of Philadelphia , Philadelphia , Pennsylvania

Fellowship

  • Children's Hospital Boston / Dana Farber Cancer Institute , Boston , MA

CERTIFICATIONS

  • American Board of Pediatrics, General Pediatrics

PUBLICATIONS

Publications powered by Harvard Catalyst Profiles

  1. Mouw KW, D'Andrea AD. DNA Repair Deficiency and Immunotherapy Response. J Clin Oncol. 2018 Apr 23; JCO2018782425. View abstract
  2. Deraska PV, O'Leary C, Reavis HD, Labe S, Dinh TK, Lazaro JB, Sweeney C, D'Andrea AD, Kozono D. NF-?B inhibition by dimethylaminoparthenolide radiosensitizes non-small-cell lung carcinoma by blocking DNA double-strand break repair. Cell Death Discov. 2018 Dec; 4:10. View abstract
  3. Rondinelli B, Gogola E, Yücel H, Duarte AA, van de Ven M, van der Sluijs R, Konstantinopoulos PA, Jonkers J, Ceccaldi R, Rottenberg S, D'Andrea AD. EZH2 promotes degradation of stalled replication forks by recruiting MUS81 through histone H3 trimethylation. Nat Cell Biol. 2017 Nov; 19(11):1371-1378. View abstract
  4. Rodríguez A, D'Andrea A. Fanconi anemia pathway. Curr Biol. 2017 Sep 25; 27(18):R986-R988. View abstract
  5. Maruvka YE, Mouw KW, Karlic R, Parasuraman P, Kamburov A, Polak P, Haradhvala NJ, Hess JM, Rheinbay E, Brody Y, Koren A, Braunstein LZ, D'Andrea A, Lawrence MS, Bass A, Bernards A, Michor F, Getz G. Analysis of somatic microsatellite indels identifies driver events in human tumors. Nat Biotechnol. 2017 Oct; 35(10):951-959. View abstract
  6. Polak P, Kim J, Braunstein LZ, Karlic R, Haradhavala NJ, Tiao G, Rosebrock D, Livitz D, Kübler K, Mouw KW, Kamburov A, Maruvka YE, Leshchiner I, Lander ES, Golub TR, Zick A, Orthwein A, Lawrence MS, Batra RN, Caldas C, Haber DA, Laird PW, Shen H, Ellisen LW, D'Andrea AD, Chanock SJ, Foulkes WD, Getz G. A mutational signature reveals alterations underlying deficient homologous recombination repair in breast cancer. Nat Genet. 2017 Oct; 49(10):1476-1486. View abstract
  7. Mouw KW, Goldberg MS, Konstantinopoulos PA, D'Andrea AD. DNA Damage and Repair Biomarkers of Immunotherapy Response. Cancer Discov. 2017 07; 7(7):675-693. View abstract
  8. Parmar K, D'Andrea AD. Aldehydes Pose a Threat to BRCA2 Mutation Carriers. Cell. 2017 06 01; 169(6):979-981. View abstract
  9. Bluteau D, Masliah-Planchon J, Clairmont C, Rousseau A, Ceccaldi R, d'Enghien CD, Bluteau O, Cuccuini W, Gachet S, de Latour RP, Leblanc T, Socié G, Baruchel A, Stoppa-Lyonnet D, D'Andrea AD, Soulier J. Biallelic inactivation of REV7 is associated with Fanconi anemia. J Clin Invest. 2017 03 01; 127(3):1117. View abstract
  10. Karras GI, Yi S, Sahni N, Fischer M, Xie J, Vidal M, D'Andrea AD, Whitesell L, Lindquist S. HSP90 Shapes the Consequences of Human Genetic Variation. Cell. 2017 Feb 23; 168(5):856-866.e12. View abstract
  11. Howitt BE, Strickland KC, Sholl LM, Rodig S, Ritterhouse LL, Chowdhury D, D'Andrea AD, Matulonis UA, Konstantinopoulos PA. Clear cell ovarian cancers with microsatellite instability: A unique subset of ovarian cancers with increased tumor-infiltrating lymphocytes and PD-1/PD-L1 expression. Oncoimmunology. 2017; 6(2):e1277308. View abstract
  12. Jo U, Cai W, Wang J, Kwon Y, D'Andrea AD, Kim H. PCNA-Dependent Cleavage and Degradation of SDE2 Regulates Response to Replication Stress. PLoS Genet. 2016 Dec; 12(12):e1006465. View abstract
  13. Johnson SF, Cruz C, Greifenberg AK, Dust S, Stover DG, Chi D, Primack B, Cao S, Bernhardy AJ, Coulson R, Lazaro JB, Kochupurakkal B, Sun H, Unitt C, Moreau LA, Sarosiek KA, Scaltriti M, Juric D, Baselga J, Richardson AL, Rodig SJ, D'Andrea AD, Balmaña J, Johnson N, Geyer M, Serra V, Lim E, Shapiro GI. CDK12 Inhibition Reverses De Novo and Acquired PARP Inhibitor Resistance in BRCA Wild-Type and Mutated Models of Triple-Negative Breast Cancer. Cell Rep. 2016 11 22; 17(9):2367-2381. View abstract
  14. Mouw KW, Cleary JM, Reardon B, Pike J, Braunstein LZ, Kim J, Amin-Mansour A, Miao D, Damish A, Chin J, Ott PA, Fuchs CS, Martin NE, Getz G, Carter S, Mamon HJ, Hornick JL, Van Allen EM, D'Andrea AD. Genomic Evolution after Chemoradiotherapy in Anal Squamous Cell Carcinoma. Clin Cancer Res. 2017 Jun 15; 23(12):3214-3222. View abstract
  15. Davis MI, Pragani R, Fox JT, Shen M, Parmar K, Gaudiano EF, Liu L, Tanega C, McGee L, Hall MD, McKnight C, Shinn P, Nelson H, Chattopadhyay D, D'Andrea AD, Auld DS, DeLucas LJ, Li Z, Boxer MB, Simeonov A. Small Molecule Inhibition of the Ubiquitin-specific Protease USP2 Accelerates cyclin D1 Degradation and Leads to Cell Cycle Arrest in Colorectal Cancer and Mantle Cell Lymphoma Models. J Biol Chem. 2016 Nov 18; 291(47):24628-24640. View abstract
  16. Bluteau D, Masliah-Planchon J, Clairmont C, Rousseau A, Ceccaldi R, Dubois d'Enghien C, Bluteau O, Cuccuini W, Gachet S, Peffault de Latour R, Leblanc T, Socié G, Baruchel A, Stoppa-Lyonnet D, D'Andrea AD, Soulier J. Biallelic inactivation of REV7 is associated with Fanconi anemia. J Clin Invest. 2016 Sep 01; 126(9):3580-4. View abstract
  17. Li H, Lim KS, Kim H, Hinds TR, Jo U, Mao H, Weller CE, Sun J, Chatterjee C, D'Andrea AD, Zheng N. Allosteric Activation of Ubiquitin-Specific Proteases by ß-Propeller Proteins UAF1 and WDR20. Mol Cell. 2016 07 21; 63(2):249-260. View abstract
  18. Kais Z, Rondinelli B, Holmes A, O'Leary C, Kozono D, D'Andrea AD, Ceccaldi R. FANCD2 Maintains Fork Stability in BRCA1/2-Deficient Tumors and Promotes Alternative End-Joining DNA Repair. Cell Rep. 2016 06 14; 15(11):2488-99. View abstract
  19. Ceccaldi R, Sarangi P, D'Andrea AD. The Fanconi anaemia pathway: new players and new functions. Nat Rev Mol Cell Biol. 2016 06; 17(6):337-49. View abstract
  20. Wang Y, Bernhardy AJ, Cruz C, Krais JJ, Nacson J, Nicolas E, Peri S, van der Gulden H, van der Heijden I, O'Brien SW, Zhang Y, Harrell MI, Johnson SF, Candido Dos Reis FJ, Pharoah PD, Karlan B, Gourley C, Lambrechts D, Chenevix-Trench G, Olsson H, Benitez JJ, Greene MH, Gore M, Nussbaum R, Sadetzki S, Gayther SA, Kjaer SK, D'Andrea AD, Shapiro GI, Wiest DL, Connolly DC, Daly MB, Swisher EM, Bouwman P, Jonkers J, Balmaña J, Serra V, Johnson N. The BRCA1-?11q Alternative Splice Isoform Bypasses Germline Mutations and Promotes Therapeutic Resistance to PARP Inhibition and Cisplatin. Cancer Res. 2016 05 01; 76(9):2778-90. View abstract
  21. Dinh TK, Fendler W, Chalubinska-Fendler J, Acharya SS, O'Leary C, Deraska PV, D'Andrea AD, Chowdhury D, Kozono D. Circulating miR-29a and miR-150 correlate with delivered dose during thoracic radiation therapy for non-small cell lung cancer. Radiat Oncol. 2016 Apr 27; 11:61. View abstract
  22. Kim J, Mouw KW, Polak P, Braunstein LZ, Kamburov A, Kwiatkowski DJ, Rosenberg JE, Van Allen EM, D'Andrea A, Getz G. Somatic ERCC2 mutations are associated with a distinct genomic signature in urothelial tumors. Nat Genet. 2016 06; 48(6):600-606. View abstract
  23. Zhang H, Kozono DE, O'Connor KW, Vidal-Cardenas S, Rousseau A, Hamilton A, Moreau L, Gaudiano EF, Greenberger J, Bagby G, Soulier J, Grompe M, Parmar K, D'Andrea AD. TGF-ß Inhibition Rescues Hematopoietic Stem Cell Defects and Bone Marrow Failure in Fanconi Anemia. Cell Stem Cell. 2016 05 05; 18(5):668-81. View abstract
  24. Strickland KC, Howitt BE, Shukla SA, Rodig S, Ritterhouse LL, Liu JF, Garber JE, Chowdhury D, Wu CJ, D'Andrea AD, Matulonis UA, Konstantinopoulos PA. Association and prognostic significance of BRCA1/2-mutation status with neoantigen load, number of tumor-infiltrating lymphocytes and expression of PD-1/PD-L1 in high grade serous ovarian cancer. Oncotarget. 2016 Mar 22; 7(12):13587-98. View abstract
  25. Mouw KW, D'Andrea AD, Konstantinopoulos PA. Nucleotide excision repair (NER) alterations as evolving biomarkers and therapeutic targets in epithelial cancers. Oncoscience. 2015; 2(12):942-3. View abstract
  26. Howitt BE, Shukla SA, Sholl LM, Ritterhouse LL, Watkins JC, Rodig S, Stover E, Strickland KC, D'Andrea AD, Wu CJ, Matulonis UA, Konstantinopoulos PA. Association of Polymerase e-Mutated and Microsatellite-Instable Endometrial Cancers With Neoantigen Load, Number of Tumor-Infiltrating Lymphocytes, and Expression of PD-1 and PD-L1. JAMA Oncol. 2015 Dec; 1(9):1319-23. View abstract
  27. Konstantinopoulos PA, Ceccaldi R, Shapiro GI, D'Andrea AD. Homologous Recombination Deficiency: Exploiting the Fundamental Vulnerability of Ovarian Cancer. Cancer Discov. 2015 Nov; 5(11):1137-54. View abstract
  28. Ceccaldi R, Rondinelli B, D'Andrea AD. Repair Pathway Choices and Consequences at the Double-Strand Break. Trends Cell Biol. 2016 Jan; 26(1):52-64. View abstract
  29. Xie J, Kim H, Moreau LA, Puhalla S, Garber J, Al Abo M, Takeda S, D'Andrea AD. RNF4-mediated polyubiquitination regulates the Fanconi anemia/BRCA pathway. J Clin Invest. 2015 Apr; 125(4):1523-32. View abstract
  30. Ceccaldi R, Liu JC, Amunugama R, Hajdu I, Primack B, Petalcorin MI, O'Connor KW, Konstantinopoulos PA, Elledge SJ, Boulton SJ, Yusufzai T, D'Andrea AD. Homologous-recombination-deficient tumours are dependent on Pol?-mediated repair. Nature. 2015 Feb 12; 518(7538):258-62. View abstract
  31. Ceccaldi R, O'Connor KW, Mouw KW, Li AY, Matulonis UA, D'Andrea AD, Konstantinopoulos PA. A unique subset of epithelial ovarian cancers with platinum sensitivity and PARP inhibitor resistance. Cancer Res. 2015 Feb 15; 75(4):628-34. View abstract
  32. Kushwaha D, O'Leary C, Cron KR, Deraska P, Zhu K, D'Andrea AD, Kozono D. USP9X inhibition promotes radiation-induced apoptosis in non-small cell lung cancer cells expressing mid-to-high MCL1. Cancer Biol Ther. 2015; 16(3):392-401. View abstract
  33. Orii M, Tanimoto T, Yokoyama M, Ota S, Kubo T, Hirata K, Tanaka A, Imanishi T, Akasaka T, Michelsen M, Pena A, Mygind N, Hoest N, Prescott E, Abd El Dayem S, Battah A, Abd El Azzez F, Ahmed A, Fattoh A, Ismail R, Andjelkovic K, Kalimanovska Ostric D, Nedeljkovic I, Andjelkovic I, Rashid H, Abuel Enien H, Ibraheem M, Vago H, Toth A, Csecs I, Czimbalmos C, Suhai FI, Kecskes K, Becker D, Simor T, Merkely B, D'ascenzi F, Pelliccia A, Natali B, Cameli M, Lisi M, Focardi M, Corrado D, Bonifazi M, Mondillo S, Zaha V, Kim G, Su K, Zhang J, Mikush N, Ross J, Palmeri M, Young L, Tadic M, Ilic S, Celic V, Jaimes C, Gonzalez Mirelis J, Gallego M, Goirigolzarri J, Pellegrinet M, Poli S, Prati G, Vriz O, Di Bello V, Carerj S, Zito C, Mateescu A, Popescu B, Antonini-Canterin F, Chatzistamatiou E, Moustakas G, Memo G, Konstantinidis D, Mpampatzeva Vagena I, Manakos K, Traxanas K, Vergi N, Feretou A, Kallikazaros I, Hewing B, Theres L, Dreger H, Spethmann S, Stangl K, Baumann G, Knebel F, Uejima T, Itatani K, Nakatani S, Lancellotti P, Seo Y, Zamorano J, Ohte N, Takenaka K, Naar J, Mortensen L, Johnson J, Winter R, Shahgaldi K, Manouras A, Braunschweig F, Stahlberg M, Coisne D, Al Arnaout AM, Tchepkou C, Raud Raynier P, Diakov C, Degand B, Christiaens L, Barbier P, Mirea O, Cefalu C, Savioli G, Guglielmo M, Maltagliati A, O'neill L, Walsh K, Hogan J, Manzoor T, Ahern B, Owens P, Savioli G, Guglielmo M, Mirea O, Cefalu C, Barbier P, Sengelov M, Biering-Sorensen T, Jorgensen P, Bruun N, Fritz-Hansen T, Bech J, Olsen F, Sivertsen J, Jensen J, Marta L, Abecasis J, Reis C, Ribeiras R, Andrade M, Mendes M, D'andrea A, Stanziola A, Di Palma E, Martino M, Lanza M, Betancourt V, Maglione M, Calabro' R, Russo M, Bossone E, Vogt MO, Meierhofer Ch, Rutz T, Fratz S, Ewert P, Roehlig Ch, Kuehn A, Storsten P, Eriksen M, Remme E, Boe E, Smiseth O, Skulstad H, Ereminiene E, Ordiene R, Ivanauskas V, Vaskelyte J, Stoskute N, Kazakauskaite E, Benetis R, Marketou M, Parthenakis F, Kontaraki J, Zacharis E, Maragkoudakis S, Logakis J, Roufas K, Vougia D, Vardas P, Dado E, Dado E, Knuti G, Djamandi J, Shota E, Sharka I, Saka J, Halmai L, Nemes A, Kardos A, Neubauer S, Kurnicka K, Domienik-Karlowicz J, Lichodziejewska B, Goliszek S, Grudzka K, Krupa M, Dzikowska-Diduch O, Ciurzynski M, Pruszczyk P, Chung H, Kim J, Yoon Y, Min P, Lee B, Hong B, Rim S, Kwon H, Choi E, Soya O, Kuryata O, Kakihara R, Naruse C, Inayoshi A, El Sebaie M, Frer A, Abdelsamie M, Eldamanhory A, Ciampi Q, Cortigiani L, Simioniuc A, Manicardi C, Villari B, Picano E, Sicari R, Ferferieva V, Deluyker D, Lambrichts I, Rigo J, Bito V, Kuznetsov V, Yaroslavskaya E, Krinochkin D, Pushkarev G, Gorbatenko E, Trzcinski P, Michalski B, Lipiec P, Szymczyk E, Peczek L, Nawrot B, Chrzanowski L, Kasprzak J, Todaro M, Zito C, Khandheria B, Cusma-Piccione M, La Carrubba S, Antonini-Canterin F, Di Bello V, Oreto G, Di Bella G, Carerj S, Gunyeli E, Oliveira Da Silva C, Sahlen A, Manouras A, Winter R, Shahgaldi K, Spampinato R, Tasca M, Roche E Silva J, Strotdrees E, Schloma V, Dmitrieva Y, Dobrovie M, Borger M, Mohr F, Einarsen E, Cramariuc D, Lonnebakken M, Boman K, Gohlke-Barwolf C, Chambers J, Gerdts E, Calin A, Rosca M, Beladan C, Mirescu Craciun A, Gurzun M, Mateescu A, Enache R, Ginghina C, Popescu B, Antova E, Georgievska Ismail Lj, Srbinovska E, Andova V, Peovska I, Davceva J, Otljanska M, Vavulkis M, Tsuruta H, Kohsaka S, Murata M, Yasuda R, Dan M, Yashima F, Inohara T, Maekawa Y, Hayashida K, Fukuda K, Migliore R, Adaniya M, Barranco M, Miramont G, Gonzalez S, Tamagusuku H, Abid L, Ben Kahla S, Charfeddine S, Abid D, Kammoun S, Amano M, Izumi C, Miyake M, Tamura T, Kondo H, Kaitani K, Nakagawa Y, Ghulam Ali S, Fusini L, Tamborini G, Muratori M, Gripari P, Bottari V, Celeste F, Cefalu' C, Alamanni F, Pepi M, Obase K, Mor-Avi V, Weinert L, Lang R, Teixeira R, Monteiro R, Garcia J, Ribeiro M, Cardim N, Goncalves L, Miglioranza M, Muraru D, Cavalli G, Addetia K, Cucchini U, Mihaila S, Tadic M, et al. Poster session 4: Friday 5 December 2014, 08:30-12:30Location: Poster area. Eur Heart J Cardiovasc Imaging. 2014 Dec; 15 Suppl 2:ii168-ii195. View abstract
  34. Wojtaszek JL, Wang S, Kim H, Wu Q, D'Andrea AD, Zhou P. Ubiquitin recognition by FAAP20 expands the complex interface beyond the canonical UBZ domain. Nucleic Acids Res. 2014 Dec 16; 42(22):13997-4005. View abstract
  35. Van Allen EM, Mouw KW, Kim P, Iyer G, Wagle N, Al-Ahmadie H, Zhu C, Ostrovnaya I, Kryukov GV, O'Connor KW, Sfakianos J, Garcia-Grossman I, Kim J, Guancial EA, Bambury R, Bahl S, Gupta N, Farlow D, Qu A, Signoretti S, Barletta JA, Reuter V, Boehm J, Lawrence M, Getz G, Kantoff P, Bochner BH, Choueiri TK, Bajorin DF, Solit DB, Gabriel S, D'Andrea A, Garraway LA, Rosenberg JE. Somatic ERCC2 mutations correlate with cisplatin sensitivity in muscle-invasive urothelial carcinoma. Cancer Discov. 2014 Oct; 4(10):1140-53. View abstract
  36. Choi YE, Pan Y, Park E, Konstantinopoulos P, De S, D'Andrea A, Chowdhury D. MicroRNAs down-regulate homologous recombination in the G1 phase of cycling cells to maintain genomic stability. Elife. 2014 Apr 30; 3:e02445. View abstract
  37. Mouw KW, D'Andrea AD. Crosstalk between the nucleotide excision repair and Fanconi anemia/BRCA pathways. DNA Repair (Amst). 2014 Jul; 19:130-4. View abstract
  38. Kim H, Dejsuphong D, Adelmant G, Ceccaldi R, Yang K, Marto JA, D'Andrea AD. Transcriptional repressor ZBTB1 promotes chromatin remodeling and translesion DNA synthesis. Mol Cell. 2014 Apr 10; 54(1):107-118. View abstract
  39. Polito D, Cukras S, Wang X, Spence P, Moreau L, D'Andrea AD, Kee Y. The carboxyl terminus of FANCE recruits FANCD2 to the Fanconi Anemia (FA) E3 ligase complex to promote the FA DNA repair pathway. J Biol Chem. 2014 Mar 07; 289(10):7003-10. View abstract
  40. Etemadmoghadam D, Weir BA, Au-Yeung G, Alsop K, Mitchell G, George J, Davis S, D'Andrea AD, Simpson K, Hahn WC, Bowtell DD. Synthetic lethality between CCNE1 amplification and loss of BRCA1. Proc Natl Acad Sci U S A. 2013 Nov 26; 110(48):19489-94. View abstract
  41. Mistry H, Hsieh G, Buhrlage SJ, Huang M, Park E, Cuny GD, Galinsky I, Stone RM, Gray NS, D'Andrea AD, Parmar K. Small-molecule inhibitors of USP1 target ID1 degradation in leukemic cells. Mol Cancer Ther. 2013 Dec; 12(12):2651-62. View abstract
  42. Johnson N, Johnson SF, Yao W, Li YC, Choi YE, Bernhardy AJ, Wang Y, Capelletti M, Sarosiek KA, Moreau LA, Chowdhury D, Wickramanayake A, Harrell MI, Liu JF, D'Andrea AD, Miron A, Swisher EM, Shapiro GI. Stabilization of mutant BRCA1 protein confers PARP inhibitor and platinum resistance. Proc Natl Acad Sci U S A. 2013 Oct 15; 110(42):17041-6. View abstract
  43. Cron KR, Zhu K, Kushwaha DS, Hsieh G, Merzon D, Rameseder J, Chen CC, D'Andrea AD, Kozono D. Proteasome inhibitors block DNA repair and radiosensitize non-small cell lung cancer. PLoS One. 2013; 8(9):e73710. View abstract
  44. Adelman CA, Lolo RL, Birkbak NJ, Murina O, Matsuzaki K, Horejsi Z, Parmar K, Borel V, Skehel JM, Stamp G, D'Andrea A, Sartori AA, Swanton C, Boulton SJ. HELQ promotes RAD51 paralogue-dependent repair to avert germ cell loss and tumorigenesis. Nature. 2013 Oct 17; 502(7471):381-4. View abstract
  45. Park E, Kim JM, Primack B, Weinstock DM, Moreau LA, Parmar K, D'Andrea AD. Inactivation of Uaf1 causes defective homologous recombination and early embryonic lethality in mice. Mol Cell Biol. 2013 Nov; 33(22):4360-70. View abstract
  46. Park E, Kim H, Kim JM, Primack B, Vidal-Cardenas S, Xu Y, Price BD, Mills AA, D'Andrea AD. FANCD2 activates transcription of TAp63 and suppresses tumorigenesis. Mol Cell. 2013 Jun 27; 50(6):908-18. View abstract
  47. D'Andrea AD. BRCA1: a missing link in the Fanconi anemia/BRCA pathway. Cancer Discov. 2013 Apr; 3(4):376-8. View abstract
  48. Price BD, D'Andrea AD. Chromatin remodeling at DNA double-strand breaks. Cell. 2013 Mar 14; 152(6):1344-54. View abstract
  49. O'Connor KW, Dejsuphong D, Park E, Nicolae CM, Kimmelman AC, D'Andrea AD, Moldovan GL. PARI overexpression promotes genomic instability and pancreatic tumorigenesis. Cancer Res. 2013 Apr 15; 73(8):2529-39. View abstract
  50. Parmar K, D'Andrea AD. Stressed out: endogenous aldehydes damage hematopoietic stem cells. Cell Stem Cell. 2012 Nov 02; 11(5):583-4. View abstract
  51. Kee Y, D'Andrea AD. Molecular pathogenesis and clinical management of Fanconi anemia. J Clin Invest. 2012 Nov; 122(11):3799-806. View abstract
  52. Wojtaszek J, Lee CJ, D'Souza S, Minesinger B, Kim H, D'Andrea AD, Walker GC, Zhou P. Structural basis of Rev1-mediated assembly of a quaternary vertebrate translesion polymerase complex consisting of Rev1, heterodimeric polymerase (Pol) ?, and Pol ?. J Biol Chem. 2012 Sep 28; 287(40):33836-46. View abstract
  53. Moldovan GL, D'Andrea AD. To the rescue: the Fanconi anemia genome stability pathway salvages replication forks. Cancer Cell. 2012 Jul 10; 22(1):5-6. View abstract
  54. Kim H, D'Andrea AD. Regulation of DNA cross-link repair by the Fanconi anemia/BRCA pathway. Genes Dev. 2012 Jul 01; 26(13):1393-408. View abstract
  55. Ceccaldi R, Parmar K, Mouly E, Delord M, Kim JM, Regairaz M, Pla M, Vasquez N, Zhang QS, Pondarre C, Peffault de Latour R, Gluckman E, Cavazzana-Calvo M, Leblanc T, Larghero J, Grompe M, Socié G, D'Andrea AD, Soulier J. Bone marrow failure in Fanconi anemia is triggered by an exacerbated p53/p21 DNA damage response that impairs hematopoietic stem and progenitor cells. Cell Stem Cell. 2012 Jul 06; 11(1):36-49. View abstract
  56. Jacquemont C, Simon JA, D'Andrea AD, Taniguchi T. Non-specific chemical inhibition of the Fanconi anemia pathway sensitizes cancer cells to cisplatin. Mol Cancer. 2012 Apr 26; 11:26. View abstract
  57. Kang J, D'Andrea AD, Kozono D. A DNA repair pathway-focused score for prediction of outcomes in ovarian cancer treated with platinum-based chemotherapy. J Natl Cancer Inst. 2012 May 02; 104(9):670-81. View abstract
  58. Bunting SF, Callén E, Kozak ML, Kim JM, Wong N, López-Contreras AJ, Ludwig T, Baer R, Faryabi RB, Malhowski A, Chen HT, Fernandez-Capetillo O, D'Andrea A, Nussenzweig A. BRCA1 functions independently of homologous recombination in DNA interstrand crosslink repair. Mol Cell. 2012 Apr 27; 46(2):125-35. View abstract
  59. Müller LU, Milsom MD, Harris CE, Vyas R, Brumme KM, Parmar K, Moreau LA, Schambach A, Park IH, London WB, Strait K, Schlaeger T, Devine AL, Grassman E, D'Andrea A, Daley GQ, Williams DA. Overcoming reprogramming resistance of Fanconi anemia cells. Blood. 2012 Jun 07; 119(23):5449-57. View abstract
  60. Kim H, Yang K, Dejsuphong D, D'Andrea AD. Regulation of Rev1 by the Fanconi anemia core complex. Nat Struct Mol Biol. 2012 Jan 22; 19(2):164-70. View abstract
  61. Kee Y, Huang M, Chang S, Moreau LA, Park E, Smith PG, D'Andrea AD. Inhibition of the Nedd8 system sensitizes cells to DNA interstrand cross-linking agents. Mol Cancer Res. 2012 Mar; 10(3):369-77. View abstract
  62. Moldovan GL, Dejsuphong D, Petalcorin MI, Hofmann K, Takeda S, Boulton SJ, D'Andrea AD. Inhibition of homologous recombination by the PCNA-interacting protein PARI. Mol Cell. 2012 Jan 13; 45(1):75-86. View abstract
  63. Alexander BM, Pinnell N, Wen PY, D'Andrea A. Targeting DNA repair and the cell cycle in glioblastoma. J Neurooncol. 2012 May; 107(3):463-77. View abstract
  64. Guinan EC, Barbon CM, Kalish LA, Parmar K, Kutok J, Mancuso CJ, Stoler-Barak L, Suter EE, Russell JD, Palmer CD, Gallington LC, Voskertchian A, Vergilio JA, Cole G, Zhu K, D'Andrea A, Soiffer R, Weiss JP, Levy O. Bactericidal/permeability-increasing protein (rBPI21) and fluoroquinolone mitigate radiation-induced bone marrow aplasia and death. Sci Transl Med. 2011 Nov 23; 3(110):110ra118. View abstract
  65. Ayrapetov MK, Xu C, Sun Y, Zhu K, Parmar K, D'Andrea AD, Price BD. Activation of Hif1a by the prolylhydroxylase inhibitor dimethyoxalyglycine decreases radiosensitivity. PLoS One. 2011; 6(10):e26064. View abstract
  66. Huang M, Kennedy R, Ali AM, Moreau LA, Meetei AR, D'Andrea AD, Chen CC. Human MutS and FANCM complexes function as redundant DNA damage sensors in the Fanconi Anemia pathway. DNA Repair (Amst). 2011 Dec 10; 10(12):1203-12. View abstract
  67. Hendel A, Krijger PH, Diamant N, Goren Z, Langerak P, Kim J, Reissner T, Lee KY, Geacintov NE, Carell T, Myung K, Tateishi S, D'Andrea A, Jacobs H, Livneh Z. PCNA ubiquitination is important, but not essential for translesion DNA synthesis in mammalian cells. PLoS Genet. 2011 Sep; 7(9):e1002262. View abstract
  68. Yang K, Moldovan GL, Vinciguerra P, Murai J, Takeda S, D'Andrea AD. Regulation of the Fanconi anemia pathway by a SUMO-like delivery network. Genes Dev. 2011 Sep 01; 25(17):1847-58. View abstract
  69. Vaezi A, Wang X, Buch S, Gooding W, Wang L, Seethala RR, Weaver DT, D'Andrea AD, Argiris A, Romkes M, Niedernhofer LJ, Grandis JR. XPF expression correlates with clinical outcome in squamous cell carcinoma of the head and neck. Clin Cancer Res. 2011 Aug 15; 17(16):5513-22. View abstract
  70. Johnson N, Li YC, Walton ZE, Cheng KA, Li D, Rodig SJ, Moreau LA, Unitt C, Bronson RT, Thomas HD, Newell DR, D'Andrea AD, Curtin NJ, Wong KK, Shapiro GI. Compromised CDK1 activity sensitizes BRCA-proficient cancers to PARP inhibition. Nat Med. 2011 Jun 26; 17(7):875-82. View abstract
  71. Kao WH, Riker AI, Kushwaha DS, Ng K, Enkemann SA, Jove R, Buettner R, Zinn PO, Sánchez NP, Villa JL, D'Andrea AD, Sánchez JL, Kennedy RD, Chen CC, Matta JL. Upregulation of Fanconi anemia DNA repair genes in melanoma compared with non-melanoma skin cancer. J Invest Dermatol. 2011 Oct; 131(10):2139-42. View abstract
  72. Moldovan GL, D'Andrea AD. DNA damage discrimination at stalled replication forks by the Rad5 homologs HLTF and SHPRH. Mol Cell. 2011 Apr 22; 42(2):141-3. View abstract
  73. Murai J, Yang K, Dejsuphong D, Hirota K, Takeda S, D'Andrea AD. The USP1/UAF1 complex promotes double-strand break repair through homologous recombination. Mol Cell Biol. 2011 Jun; 31(12):2462-9. View abstract
  74. Alexander BM, Sprott K, Farrow DA, Wang X, D'Andrea AD, Schnitt SJ, Collins LC, Weaver DT, Garber JE. DNA repair protein biomarkers associated with time to recurrence in triple-negative breast cancer. Clin Cancer Res. 2010 Dec 01; 16(23):5796-804. View abstract
  75. Vinciguerra P, Godinho SA, Parmar K, Pellman D, D'Andrea AD. Cytokinesis failure occurs in Fanconi anemia pathway-deficient murine and human bone marrow hematopoietic cells. J Clin Invest. 2010 Nov; 120(11):3834-42. View abstract
  76. D'Andrea AD. Targeting DNA repair pathways in AML. Best Pract Res Clin Haematol. 2010 Dec; 23(4):469-73. View abstract
  77. Kee Y, D'Andrea AD. Expanded roles of the Fanconi anemia pathway in preserving genomic stability. Genes Dev. 2010 Aug 15; 24(16):1680-94. View abstract
  78. Huang M, D'Andrea AD. A new nuclease member of the FAN club. Nat Struct Mol Biol. 2010 Aug; 17(8):926-8. View abstract
  79. Huang M, Kim JM, Shiotani B, Yang K, Zou L, D'Andrea AD. The FANCM/FAAP24 complex is required for the DNA interstrand crosslink-induced checkpoint response. Mol Cell. 2010 Jul 30; 39(2):259-68. View abstract
  80. Parmar K, Kim J, Sykes SM, Shimamura A, Stuckert P, Zhu K, Hamilton A, Deloach MK, Kutok JL, Akashi K, Gilliland DG, D'andrea A. Hematopoietic stem cell defects in mice with deficiency of Fancd2 or Usp1. Stem Cells. 2010 Jul; 28(7):1186-95. View abstract
  81. Nitta M, Kozono D, Kennedy R, Stommel J, Ng K, Zinn PO, Kushwaha D, Kesari S, Inda MM, Wykosky J, Furnari F, Hoadley KA, Chin L, DePinho RA, Cavenee WK, D'Andrea A, Chen CC. Targeting EGFR induced oxidative stress by PARP1 inhibition in glioblastoma therapy. PLoS One. 2010 May 24; 5(5):e10767. View abstract
  82. D'Andrea AD. Susceptibility pathways in Fanconi's anemia and breast cancer. N Engl J Med. 2010 May 20; 362(20):1909-19. View abstract
  83. Yang K, Moldovan GL, D'Andrea AD. RAD18-dependent recruitment of SNM1A to DNA repair complexes by a ubiquitin-binding zinc finger. J Biol Chem. 2010 Jun 18; 285(25):19085-91. View abstract
  84. Kee Y, Yang K, Cohn MA, Haas W, Gygi SP, D'Andrea AD. WDR20 regulates activity of the USP12 x UAF1 deubiquitinating enzyme complex. J Biol Chem. 2010 Apr 09; 285(15):11252-7. View abstract
  85. Lee KY, Yang K, Cohn MA, Sikdar N, D'Andrea AD, Myung K. Human ELG1 regulates the level of ubiquitinated proliferating cell nuclear antigen (PCNA) through Its interactions with PCNA and USP1. J Biol Chem. 2010 Apr 02; 285(14):10362-9. View abstract
  86. Tulpule A, Lensch MW, Miller JD, Austin K, D'Andrea A, Schlaeger TM, Shimamura A, Daley GQ. Knockdown of Fanconi anemia genes in human embryonic stem cells reveals early developmental defects in the hematopoietic lineage. Blood. 2010 Apr 29; 115(17):3453-62. View abstract
  87. Vinciguerra P, D'Andrea AD. FANCM: A landing pad for the Fanconi Anemia and Bloom's Syndrome complexes. Mol Cell. 2009 Dec 25; 36(6):916-7. View abstract
  88. Moldovan GL, D'Andrea AD. FANCD2 hurdles the DNA interstrand crosslink. Cell. 2009 Dec 24; 139(7):1222-4. View abstract
  89. Moldovan GL, Madhavan MV, Mirchandani KD, McCaffrey RM, Vinciguerra P, D'Andrea AD. DNA polymerase POLN participates in cross-link repair and homologous recombination. Mol Cell Biol. 2010 Feb; 30(4):1088-96. View abstract
  90. Bhagwat N, Olsen AL, Wang AT, Hanada K, Stuckert P, Kanaar R, D'Andrea A, Niedernhofer LJ, McHugh PJ. XPF-ERCC1 participates in the Fanconi anemia pathway of cross-link repair. Mol Cell Biol. 2009 Dec; 29(24):6427-37. View abstract
  91. Johnson N, Cai D, Kennedy RD, Pathania S, Arora M, Li YC, D'Andrea AD, Parvin JD, Shapiro GI. Cdk1 participates in BRCA1-dependent S phase checkpoint control in response to DNA damage. Mol Cell. 2009 Aug 14; 35(3):327-39. View abstract
  92. Chen CC, Kennedy RD, Sidi S, Look AT, D'Andrea A. CHK1 inhibition as a strategy for targeting Fanconi Anemia (FA) DNA repair pathway deficient tumors. Mol Cancer. 2009 Apr 16; 8:24. View abstract
  93. Parmar K, D'Andrea A, Niedernhofer LJ. Mouse models of Fanconi anemia. Mutat Res. 2009 Jul 31; 668(1-2):133-40. View abstract
  94. Kee Y, Kim JM, D'Andrea AD, D'Andrea A. Regulated degradation of FANCM in the Fanconi anemia pathway during mitosis. Genes Dev. 2009 Mar 01; 23(5):555-60. View abstract
  95. Kim JM, Parmar K, Huang M, Weinstock DM, Ruit CA, Kutok JL, D'Andrea AD. Inactivation of murine Usp1 results in genomic instability and a Fanconi anemia phenotype. Dev Cell. 2009 Feb; 16(2):314-20. View abstract
  96. Ng K, Nitta M, Hu L, Kesari S, Kung A, D'Andrea A, Chen CC. A small interference RNA screen revealed proteasome inhibition as strategy for glioblastoma therapy. Clin Neurosurg. 2009; 56:107-18. View abstract
  97. Moldovan GL, D'Andrea AD. How the fanconi anemia pathway guards the genome. Annu Rev Genet. 2009; 43:223-49. View abstract
  98. Cohn MA, Kee Y, Haas W, Gygi SP, D'Andrea AD. UAF1 is a subunit of multiple deubiquitinating enzyme complexes. J Biol Chem. 2009 Feb 20; 284(8):5343-51. View abstract
  99. Cohn MA, D'Andrea AD. Chromatin recruitment of DNA repair proteins: lessons from the fanconi anemia and double-strand break repair pathways. Mol Cell. 2008 Nov 07; 32(3):306-12. View abstract
  100. Mirchandani KD, McCaffrey RM, D'Andrea AD. The Fanconi anemia core complex is required for efficient point mutagenesis and Rev1 foci assembly. DNA Repair (Amst). 2008 Jun 01; 7(6):902-11. View abstract
  101. Kim JM, Kee Y, Gurtan A, D'Andrea AD. Cell cycle-dependent chromatin loading of the Fanconi anemia core complex by FANCM/FAAP24. Blood. 2008 May 15; 111(10):5215-22. View abstract
  102. Cohn MA, Kowal P, Yang K, Haas W, Huang TT, Gygi SP, D'Andrea AD. A UAF1-containing multisubunit protein complex regulates the Fanconi anemia pathway. Mol Cell. 2007 Dec 14; 28(5):786-97. View abstract
  103. Kennedy RD, Chen CC, Stuckert P, Archila EM, De la Vega MA, Moreau LA, Shimamura A, D'Andrea AD. Fanconi anemia pathway-deficient tumor cells are hypersensitive to inhibition of ataxia telangiectasia mutated. J Clin Invest. 2007 May; 117(5):1440-9. View abstract
  104. Smogorzewska A, Matsuoka S, Vinciguerra P, McDonald ER, Hurov KE, Luo J, Ballif BA, Gygi SP, Hofmann K, D'Andrea AD, Elledge SJ. Identification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repair. Cell. 2007 Apr 20; 129(2):289-301. View abstract
  105. Wang X, Kennedy RD, Ray K, Stuckert P, Ellenberger T, D'Andrea AD. Chk1-mediated phosphorylation of FANCE is required for the Fanconi anemia/BRCA pathway. Mol Cell Biol. 2007 Apr; 27(8):3098-108. View abstract
  106. Chen CC, Taniguchi T, D'Andrea A. The Fanconi anemia (FA) pathway confers glioma resistance to DNA alkylating agents. J Mol Med (Berl). 2007 May; 85(5):497-509. View abstract
  107. Kowal P, Gurtan AM, Stuckert P, D'Andrea AD, Ellenberger T. Structural determinants of human FANCF protein that function in the assembly of a DNA damage signaling complex. J Biol Chem. 2007 Jan 19; 282(3):2047-55. View abstract
  108. Huang TT, D'Andrea AD. HAUSP hunting the FOX(O). Nat Cell Biol. 2006 Oct; 8(10):1043-5. View abstract
  109. Chen CC, Motegi A, Hasegawa Y, Myung K, Kolodner R, D'Andrea A. Genetic analysis of ionizing radiation-induced mutagenesis in Saccharomyces cerevisiae reveals TransLesion Synthesis (TLS) independent of PCNA K164 SUMOylation and ubiquitination. DNA Repair (Amst). 2006 Dec 09; 5(12):1475-88. View abstract
  110. Ho GP, Margossian S, Taniguchi T, D'Andrea AD. Phosphorylation of FANCD2 on two novel sites is required for mitomycin C resistance. Mol Cell Biol. 2006 Sep; 26(18):7005-15. View abstract
  111. Kennedy RD, D'Andrea AD. DNA repair pathways in clinical practice: lessons from pediatric cancer susceptibility syndromes. J Clin Oncol. 2006 Aug 10; 24(23):3799-808. View abstract
  112. Machida YJ, Machida Y, Chen Y, Gurtan AM, Kupfer GM, D'Andrea AD, Dutta A. UBE2T is the E2 in the Fanconi anemia pathway and undergoes negative autoregulation. Mol Cell. 2006 Aug; 23(4):589-96. View abstract
  113. Chen CC, Kennedy R, D'Andrea A. A Small Interfering Ribonucleic Acid-based Approach to Characterize Brain Tumor Resistance to Radiation Therapy 893. Neurosurgery. 2006 Aug 01; 59(2):485. View abstract
  114. Mirchandani KD, D'Andrea AD. The Fanconi anemia/BRCA pathway: a coordinator of cross-link repair. Exp Cell Res. 2006 Aug 15; 312(14):2647-53. View abstract
  115. Gurtan AM, D'Andrea AD. Dedicated to the core: understanding the Fanconi anemia complex. DNA Repair (Amst). 2006 Sep 08; 5(9-10):1119-25. View abstract
  116. Huang TT, D'Andrea AD. Regulation of DNA repair by ubiquitylation. Nat Rev Mol Cell Biol. 2006 May; 7(5):323-34. View abstract
  117. Zhu AX, D'Andrea AD, Sahani DV, Hasserjian RP. Case records of the Massachusetts General Hospital. Case 13-2006. A 50-year-old man with a painful bone mass and lesions in the liver. N Engl J Med. 2006 Apr 27; 354(17):1828-37. View abstract
  118. Chirnomas D, Taniguchi T, de la Vega M, Vaidya AP, Vasserman M, Hartman AR, Kennedy R, Foster R, Mahoney J, Seiden MV, D'Andrea AD. Chemosensitization to cisplatin by inhibitors of the Fanconi anemia/BRCA pathway. Mol Cancer Ther. 2006 Apr; 5(4):952-61. View abstract
  119. Huang TT, Nijman SM, Mirchandani KD, Galardy PJ, Cohn MA, Haas W, Gygi SP, Ploegh HL, Bernards R, D'Andrea AD. Regulation of monoubiquitinated PCNA by DUB autocleavage. Nat Cell Biol. 2006 Apr; 8(4):339-47. View abstract
  120. Taniguchi T, D'Andrea AD. Molecular pathogenesis of Fanconi anemia: recent progress. Blood. 2006 Jun 01; 107(11):4223-33. View abstract
  121. Andreassen PR, Ho GP, D'Andrea AD. DNA damage responses and their many interactions with the replication fork. Carcinogenesis. 2006 May; 27(5):883-92. View abstract
  122. Gurtan AM, Stuckert P, D'Andrea AD. The WD40 repeats of FANCL are required for Fanconi anemia core complex assembly. J Biol Chem. 2006 Apr 21; 281(16):10896-905. View abstract
  123. Mankad A, Taniguchi T, Cox B, Akkari Y, Rathbun RK, Lucas L, Bagby G, Olson S, D'Andrea A, Grompe M. Natural gene therapy in monozygotic twins with Fanconi anemia. Blood. 2006 Apr 15; 107(8):3084-90. View abstract
  124. Kennedy RD, D'Andrea AD. The Fanconi Anemia/BRCA pathway: new faces in the crowd. Genes Dev. 2005 Dec 15; 19(24):2925-40. View abstract
  125. Howlett NG, Scuric Z, D'Andrea AD, Schiestl RH. Impaired DNA double strand break repair in cells from Nijmegen breakage syndrome patients. DNA Repair (Amst). 2006 Feb 03; 5(2):251-7. View abstract
  126. New HV, Cale CM, Tischkowitz M, Jones A, Telfer P, Veys P, D'Andrea A, Mathew CG, Hann I. Nijmegen breakage syndrome diagnosed as Fanconi anaemia. Pediatr Blood Cancer. 2005 May; 44(5):494-9. View abstract
  127. Park WH, Margossian S, Horwitz AA, Simons AM, D'Andrea AD, Parvin JD. Direct DNA binding activity of the Fanconi anemia D2 protein. J Biol Chem. 2005 Jun 24; 280(25):23593-8. View abstract
  128. Levine RL, Wadleigh M, Cools J, Ebert BL, Wernig G, Huntly BJ, Boggon TJ, Wlodarska I, Clark JJ, Moore S, Adelsperger J, Koo S, Lee JC, Gabriel S, Mercher T, D'Andrea A, Fröhling S, Döhner K, Marynen P, Vandenberghe P, Mesa RA, Tefferi A, Griffin JD, Eck MJ, Sellers WR, Meyerson M, Golub TR, Lee SJ, Gilliland DG. Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis. Cancer Cell. 2005 Apr; 7(4):387-97. View abstract
  129. Nijman SM, Huang TT, Dirac AM, Brummelkamp TR, Kerkhoven RM, D'Andrea AD, Bernards R. The deubiquitinating enzyme USP1 regulates the Fanconi anemia pathway. Mol Cell. 2005 Feb 04; 17(3):331-9. View abstract
  130. Howlett NG, Taniguchi T, Durkin SG, D'Andrea AD, Glover TW. The Fanconi anemia pathway is required for the DNA replication stress response and for the regulation of common fragile site stability. Hum Mol Genet. 2005 Mar 01; 14(5):693-701. View abstract
  131. Nakanishi K, Yang YG, Pierce AJ, Taniguchi T, Digweed M, D'Andrea AD, Wang ZQ, Jasin M. Human Fanconi anemia monoubiquitination pathway promotes homologous DNA repair. Proc Natl Acad Sci U S A. 2005 Jan 25; 102(4):1110-5. View abstract
  132. Montes de Oca R, Andreassen PR, Margossian SP, Gregory RC, Taniguchi T, Wang X, Houghtaling S, Grompe M, D'Andrea AD. Regulated interaction of the Fanconi anemia protein, FANCD2, with chromatin. Blood. 2005 Feb 01; 105(3):1003-9. View abstract
  133. Soulier J, Leblanc T, Larghero J, Dastot H, Shimamura A, Guardiola P, Esperou H, Ferry C, Jubert C, Feugeas JP, Henri A, Toubert A, Socié G, Baruchel A, Sigaux F, D'Andrea AD, Gluckman E. Detection of somatic mosaicism and classification of Fanconi anemia patients by analysis of the FA/BRCA pathway. Blood. 2005 Feb 01; 105(3):1329-36. View abstract
  134. Andreassen PR, D'Andrea AD, Taniguchi T. ATR couples FANCD2 monoubiquitination to the DNA-damage response. Genes Dev. 2004 Aug 15; 18(16):1958-63. View abstract
  135. Wang X, D'Andrea AD. The interplay of Fanconi anemia proteins in the DNA damage response. DNA Repair (Amst). 2004 Aug-Sep; 3(8-9):1063-9. View abstract
  136. Wang X, Andreassen PR, D'Andrea AD. Functional interaction of monoubiquitinated FANCD2 and BRCA2/FANCD1 in chromatin. Mol Cell Biol. 2004 Jul; 24(13):5850-62. View abstract
  137. Hirsch B, Shimamura A, Moreau L, Baldinger S, Hag-alshiekh M, Bostrom B, Sencer S, D'Andrea AD. Association of biallelic BRCA2/FANCD1 mutations with spontaneous chromosomal instability and solid tumors of childhood. Blood. 2004 Apr 01; 103(7):2554-9. View abstract
  138. Liu TX, Howlett NG, Deng M, Langenau DM, Hsu K, Rhodes J, Kanki JP, D'Andrea AD, Look AT. Knockdown of zebrafish Fancd2 causes developmental abnormalities via p53-dependent apoptosis. Dev Cell. 2003 Dec; 5(6):903-14. View abstract
  139. Shimamura A, D'Andrea AD. Subtyping of Fanconi anemia patients: implications for clinical management. Blood. 2003 Nov 01; 102(9):3459. View abstract
  140. Tischkowitz M, Ameziane N, Waisfisz Q, De Winter JP, Harris R, Taniguchi T, D'Andrea A, Hodgson SV, Mathew CG, Joenje H. Bi-allelic silencing of the Fanconi anaemia gene FANCF in acute myeloid leukaemia. Br J Haematol. 2003 Nov; 123(3):469-71. View abstract
  141. D'Andrea A, Severino S, Caso P, De Simone L, Liccardo B, Forni A, Pascotto M, Di Salvo G, Scherillo M, Mininni N, Calabrò R. Prognostic value of pharmacological stress echocardiography in diabetic patients. Eur J Echocardiogr. 2003 Sep; 4(3):202-8. View abstract
  142. D'Andrea AD. The Fanconi road to cancer. Genes Dev. 2003 Aug 15; 17(16):1933-6. View abstract
  143. Jin S, Mao H, Schnepp RW, Sykes SM, Silva AC, D'Andrea AD, Hua X. Menin associates with FANCD2, a protein involved in repair of DNA damage. Cancer Res. 2003 Jul 15; 63(14):4204-10. View abstract
  144. D'Andrea A. Fanconi anemia. Curr Biol. 2003 Jul 15; 13(14):R546. View abstract
  145. D'Andrea AD. The Fanconi Anemia/BRCA signaling pathway: disruption in cisplatin-sensitive ovarian cancers. Cell Cycle. 2003 Jul-Aug; 2(4):290-2. View abstract
  146. Ikeda H, Matsushita M, Waisfisz Q, Kinoshita A, Oostra AB, Nieuwint AW, De Winter JP, Hoatlin ME, Kawai Y, Sasaki MS, D'Andrea AD, Kawakami Y, Joenje H. Genetic reversion in an acute myelogenous leukemia cell line from a Fanconi anemia patient with biallelic mutations in BRCA2. Cancer Res. 2003 May 15; 63(10):2688-94. View abstract
  147. Taniguchi T, Tischkowitz M, Ameziane N, Hodgson SV, Mathew CG, Joenje H, Mok SC, D'Andrea AD. Disruption of the Fanconi anemia-BRCA pathway in cisplatin-sensitive ovarian tumors. Nat Med. 2003 May; 9(5):568-74. View abstract
  148. Gregory RC, Taniguchi T, D'Andrea AD. Regulation of the Fanconi anemia pathway by monoubiquitination. Semin Cancer Biol. 2003 Feb; 13(1):77-82. View abstract
  149. D'Andrea AD, Grompe M. The Fanconi anaemia/BRCA pathway. Nat Rev Cancer. 2003 Jan; 3(1):23-34. View abstract
  150. Nakanishi K, Taniguchi T, Ranganathan V, New HV, Moreau LA, Stotsky M, Mathew CG, Kastan MB, Weaver DT, D'Andrea AD. Interaction of FANCD2 and NBS1 in the DNA damage response. Nat Cell Biol. 2002 Dec; 4(12):913-20. View abstract
  151. Adachi D, Oda T, Yagasaki H, Nakasato K, Taniguchi T, D'Andrea AD, Asano S, Yamashita T. Heterogeneous activation of the Fanconi anemia pathway by patient-derived FANCA mutants. Hum Mol Genet. 2002 Dec 01; 11(25):3125-34. View abstract
  152. Taniguchi T, D'Andrea AD. The Fanconi anemia protein, FANCE, promotes the nuclear accumulation of FANCC. Blood. 2002 Oct 01; 100(7):2457-62. View abstract
  153. Taniguchi T, Garcia-Higuera I, Andreassen PR, Gregory RC, Grompe M, D'Andrea AD. S-phase-specific interaction of the Fanconi anemia protein, FANCD2, with BRCA1 and RAD51. Blood. 2002 Oct 01; 100(7):2414-20. View abstract
  154. Folias A, Matkovic M, Bruun D, Reid S, Hejna J, Grompe M, D'Andrea A, Moses R. BRCA1 interacts directly with the Fanconi anemia protein FANCA. Hum Mol Genet. 2002 Oct 01; 11(21):2591-7. View abstract
  155. Shimamura A, Montes de Oca R, Svenson JL, Haining N, Moreau LA, Nathan DG, D'Andrea AD. A novel diagnostic screen for defects in the Fanconi anemia pathway. Blood. 2002 Dec 15; 100(13):4649-54. View abstract
  156. Howlett NG, Taniguchi T, Olson S, Cox B, Waisfisz Q, De Die-Smulders C, Persky N, Grompe M, Joenje H, Pals G, Ikeda H, Fox EA, D'Andrea AD. Biallelic inactivation of BRCA2 in Fanconi anemia. Science. 2002 Jul 26; 297(5581):606-9. View abstract
  157. Taniguchi T, Garcia-Higuera I, Xu B, Andreassen PR, Gregory RC, Kim ST, Lane WS, Kastan MB, D'Andrea AD. Convergence of the fanconi anemia and ataxia telangiectasia signaling pathways. Cell. 2002 May 17; 109(4):459-72. View abstract
  158. D'Andrea AD, Dahl N, Guinan EC, Shimamura A. Marrow failure. Hematology Am Soc Hematol Educ Program. 2002; 58-72. View abstract
  159. Yagasaki H, Adachi D, Oda T, Garcia-Higuera I, Tetteh N, D'Andrea AD, Futaki M, Asano S, Yamashita T. A cytoplasmic serine protein kinase binds and may regulate the Fanconi anemia protein FANCA. Blood. 2001 Dec 15; 98(13):3650-7. View abstract
  160. Yang Y, Kuang Y, Montes De Oca R, Hays T, Moreau L, Lu N, Seed B, D'Andrea AD. Targeted disruption of the murine Fanconi anemia gene, Fancg/Xrcc9. Blood. 2001 Dec 01; 98(12):3435-40. View abstract
  161. D'Andrea AD. Cellular function of the Fanconi anemia pathway. Nat Med. 2001 Dec; 7(12):1259-60. View abstract
  162. Wilson JB, Johnson MA, Stuckert AP, Trueman KL, May S, Bryant PE, Meyn RE, D'Andrea AD, Jones NJ. The Chinese hamster FANCG/XRCC9 mutant NM3 fails to express the monoubiquitinated form of the FANCD2 protein, is hypersensitive to a range of DNA damaging agents and exhibits a normal level of spontaneous sister chromatid exchange. Carcinogenesis. 2001 Dec; 22(12):1939-46. View abstract
  163. Siddique MA, Nakanishi K, Taniguchi T, Grompe M, D'Andrea AD. Function of the Fanconi anemia pathway in Fanconi anemia complementation group F and D1 cells. Exp Hematol. 2001 Dec; 29(12):1448-55. View abstract
  164. Akkari YM, Bateman RL, Reifsteck CA, D'Andrea AD, Olson SB, Grompe M. The 4N cell cycle delay in Fanconi anemia reflects growth arrest in late S phase. Mol Genet Metab. 2001 Dec; 74(4):403-12. View abstract
  165. Grompe M, D'Andrea A. Fanconi anemia and DNA repair. Hum Mol Genet. 2001 Oct 01; 10(20):2253-9. View abstract
  166. Migone TS, Humbert M, Rascle A, Sanden D, D'Andrea A, Johnston JA. The deubiquitinating enzyme DUB-2 prolongs cytokine-induced signal transducers and activators of transcription activation and suppresses apoptosis following cytokine withdrawal. Blood. 2001 Sep 15; 98(6):1935-41. View abstract
  167. Baek KH, Mondoux MA, Jaster R, Fire-Levin E, D'Andrea AD. DUB-2A, a new member of the DUB subfamily of hematopoietic deubiquitinating enzymes. Blood. 2001 Aug 01; 98(3):636-42. View abstract
  168. Marcou Y, D'Andrea A, Jeggo PA, Plowman PN. Normal cellular radiosensitivity in an adult Fanconi anaemia patient with marked clinical radiosensitivity. Radiother Oncol. 2001 Jul; 60(1):75-9. View abstract
  169. Nakanishi K, Moran A, Hays T, Kuang Y, Fox E, Garneau D, Montes de Oca R, Grompe M, D'Andrea AD. Functional analysis of patient-derived mutations in the Fanconi anemia gene, FANCG/XRCC9. Exp Hematol. 2001 Jul; 29(7):842-9. View abstract
  170. Barber DL, Beattie BK, Mason JM, Nguyen MH, Yoakim M, Neel BG, D'Andrea AD, Frank DA. A common epitope is shared by activated signal transducer and activator of transcription-5 (STAT5) and the phosphorylated erythropoietin receptor: implications for the docking model of STAT activation. Blood. 2001 Apr 15; 97(8):2230-7. View abstract
  171. Timmers C, Taniguchi T, Hejna J, Reifsteck C, Lucas L, Bruun D, Thayer M, Cox B, Olson S, D'Andrea AD, Moses R, Grompe M. Positional cloning of a novel Fanconi anemia gene, FANCD2. Mol Cell. 2001 Feb; 7(2):241-8. View abstract
  172. Garcia-Higuera I, Taniguchi T, Ganesan S, Meyn MS, Timmers C, Hejna J, Grompe M, D'Andrea AD. Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway. Mol Cell. 2001 Feb; 7(2):249-62. View abstract
  173. Noll M, Bateman RL, D'Andrea AD, Grompe M. Preclinical protocol for in vivo selection of hematopoietic stem cells corrected by gene therapy in Fanconi anemia group C. Mol Ther. 2001 Jan; 3(1):14-23. View abstract
  174. Ney PA, D'Andrea AD. Friend erythroleukemia revisited. Blood. 2000 Dec 01; 96(12):3675-80. View abstract
  175. Demuth I, Wlodarski M, Tipping AJ, Morgan NV, de Winter JP, Thiel M, Gräsl S, Schindler D, D'Andrea AD, Altay C, Kayserili H, Zatterale A, Kunze J, Ebell W, Mathew CG, Joenje H, Sperling K, Digweed M. Spectrum of mutations in the Fanconi anaemia group G gene, FANCG/XRCC9. Eur J Hum Genet. 2000 Nov; 8(11):861-8. View abstract
  176. Garcia-Higuera I, Kuang Y, Denham J, D'Andrea AD. The fanconi anemia proteins FANCA and FANCG stabilize each other and promote the nuclear accumulation of the Fanconi anemia complex. Blood. 2000 Nov 01; 96(9):3224-30. View abstract
  177. Kuang Y, Garcia-Higuera I, Moran A, Mondoux M, Digweed M, D'Andrea AD. Carboxy terminal region of the Fanconi anemia protein, FANCG/XRCC9, is required for functional activity. Blood. 2000 Sep 01; 96(5):1625-32. View abstract
  178. Joenje H, Levitus M, Waisfisz Q, D'Andrea A, Garcia-Higuera I, Pearson T, van Berkel CG, Rooimans MA, Morgan N, Mathew CG, Arwert F. Complementation analysis in Fanconi anemia: assignment of the reference FA-H patient to group A. Am J Hum Genet. 2000 Sep; 67(3):759-62. View abstract
  179. D'Andrea A, Goux D, De Lalla C, Koezuka Y, Montagna D, Moretta A, Dellabona P, Casorati G, Abrignani S. Neonatal invariant Valpha24+ NKT lymphocytes are activated memory cells. Eur J Immunol. 2000 Jun; 30(6):1544-50. View abstract
  180. Jaster R, Baek KH, D'Andrea AD. Analysis of cis-acting sequences and trans-acting factors regulating the interleukin-3 response element of the DUB-1 gene. Biochim Biophys Acta. 1999 Sep 03; 1446(3):308-16. View abstract
  181. Garcia-Higuera I, Kuang Y, Näf D, Wasik J, D'Andrea AD. Fanconi anemia proteins FANCA, FANCC, and FANCG/XRCC9 interact in a functional nuclear complex. Mol Cell Biol. 1999 Jul; 19(7):4866-73. View abstract
  182. Savoia A, Garcia-Higuera I, D'Andrea AD. Nuclear localization of the Fanconi anemia protein FANCC is required for functional activity. Blood. 1999 Jun 01; 93(11):4025-6. View abstract
  183. Kupfer G, Naf D, Garcia-Higuera I, Wasik J, Cheng A, Yamashita T, Tipping A, Morgan N, Mathew CG, D'Andrea AD. A patient-derived mutant form of the Fanconi anemia protein, FANCA, is defective in nuclear accumulation. Exp Hematol. 1999 Apr; 27(4):587-93. View abstract
  184. Garcia-Higuera I, Kuang Y, D'Andrea AD. The molecular and cellular biology of Fanconi anemia. Curr Opin Hematol. 1999 Mar; 6(2):83-8. View abstract
  185. Garcia-Higuera I, D'Andrea AD. Regulated binding of the Fanconi anemia proteins, FANCA and FANCC. Blood. 1999 Feb 15; 93(4):1430-2. View abstract
  186. Okuda K, D'Andrea A, Van Etten RA, Griffin JD. The C-terminus of c-ABL is required for proliferation and viability signaling in a c-ABL/erythropoietin receptor fusion protein. Blood. 1998 Nov 15; 92(10):3848-56. View abstract
  187. Yamashita T, Kupfer GM, Naf D, Suliman A, Joenje H, Asano S, D'Andrea AD. The fanconi anemia pathway requires FAA phosphorylation and FAA/FAC nuclear accumulation. Proc Natl Acad Sci U S A. 1998 Oct 27; 95(22):13085-90. View abstract
  188. Näf D, Kupfer GM, Suliman A, Lambert K, D'Andrea AD. Functional activity of the fanconi anemia protein FAA requires FAC binding and nuclear localization. Mol Cell Biol. 1998 Oct; 18(10):5952-60. View abstract
  189. Pulsipher M, Kupfer GM, Naf D, Suliman A, Lee JS, Jakobs P, Grompe M, Joenje H, Sieff C, Guinan E, Mulligan R, D'Andrea AD. Subtyping analysis of Fanconi anemia by immunoblotting and retroviral gene transfer. Mol Med. 1998 Jul; 4(7):468-79. View abstract
  190. Braud VM, Allan DS, O'Callaghan CA, Söderström K, D'Andrea A, Ogg GS, Lazetic S, Young NT, Bell JI, Phillips JH, Lanier LL, McMichael AJ. HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C. Nature. 1998 Feb 19; 391(6669):795-9. View abstract
  191. D'Andrea AD, Serhan CN. Relieving the Itch. Nat Genet. 1998 Feb; 18(2):97-9. View abstract
  192. D'Andrea A, Lanier LL. Killer cell inhibitory receptor expression by T cells. Curr Top Microbiol Immunol. 1998; 230:25-39. View abstract
  193. D'Andrea A, Pellman D. Deubiquitinating enzymes: a new class of biological regulators. Crit Rev Biochem Mol Biol. 1998; 33(5):337-52. View abstract
  194. Valiante NM, Uhrberg M, Shilling HG, Lienert-Weidenbach K, Arnett KL, D'Andrea A, Phillips JH, Lanier LL, Parham P. Functionally and structurally distinct NK cell receptor repertoires in the peripheral blood of two human donors. Immunity. 1997 Dec; 7(6):739-51. View abstract
  195. Kupfer GM, Näf D, Suliman A, Pulsipher M, D'Andrea AD. The Fanconi anaemia proteins, FAA and FAC, interact to form a nuclear complex. Nat Genet. 1997 Dec; 17(4):487-90. View abstract
  196. Kupfer GM, Näf D, D'Andrea AD. Molecular biology of Fanconi anemia. Hematol Oncol Clin North Am. 1997 Dec; 11(6):1045-60. View abstract
  197. Okuda K, D'Andrea A, Etten RA, Griffin JD. A chimeric receptor/oncogene that can be regulated by a ligand in vitro and in vivo. J Clin Invest. 1997 Oct 01; 100(7):1708-15. View abstract
  198. D'Andrea AD, Grompe M. Molecular biology of Fanconi anemia: implications for diagnosis and therapy. Blood. 1997 Sep 01; 90(5):1725-36. View abstract
  199. Kupfer GM, Yamashita T, Naf D, Suliman A, Asano S, D'Andrea AD. The Fanconi anemia polypeptide, FAC, binds to the cyclin-dependent kinase, cdc2. Blood. 1997 Aug 01; 90(3):1047-54. View abstract
  200. Jaster R, Zhu Y, Pless M, Bhattacharya S, Mathey-Prevot B, D'Andrea AD. JAK2 is required for induction of the murine DUB-1 gene. Mol Cell Biol. 1997 Jun; 17(6):3364-72. View abstract
  201. Barber DL, Mason JM, Fukazawa T, Reedquist KA, Druker BJ, Band H, D'Andrea AD. Erythropoietin and interleukin-3 activate tyrosine phosphorylation of CBL and association with CRK adaptor proteins. Blood. 1997 May 01; 89(9):3166-74. View abstract
  202. Pless M, Norga K, Carroll M, Heim MH, D'Andrea AD, Mathey-Prevot B. Receptors that induce erythroid differentiation of Ba/F3 cells: structural requirements and effect on STAT5 binding. Blood. 1997 May 01; 89(9):3175-85. View abstract
  203. Luo H, Rose P, Barber D, Hanratty WP, Lee S, Roberts TM, D'Andrea AD, Dearolf CR. Mutation in the Jak kinase JH2 domain hyperactivates Drosophila and mammalian Jak-Stat pathways. Mol Cell Biol. 1997 Mar; 17(3):1562-71. View abstract
  204. Zhu Y, Lambert K, Corless C, Copeland NG, Gilbert DJ, Jenkins NA, D'Andrea AD. DUB-2 is a member of a novel family of cytokine-inducible deubiquitinating enzymes. J Biol Chem. 1997 Jan 03; 272(1):51-7. View abstract
  205. Zhu Y, Hahn T, D'Andrea AD. Isolation of cytokine-inducible genes from hematopoietic cells by differential display. Methods Mol Biol. 1997; 85:153-61. View abstract
  206. Barber DL, Corless CN, Xia K, Roberts TM, D'Andrea AD. Erythropoietin activates Raf1 by an Shc-independent pathway in CTLL-EPO-R cells. Blood. 1997 Jan 01; 89(1):55-64. View abstract
  207. Ku H, Hirayama F, Kato T, Miyazaki H, Aritomi M, Ota Y, D'Andrea AD, Lyman SD, Ogawa M. Soluble thrombopoietin receptor (Mpl) and granulocyte colony-stimulating factor receptor directly stimulate proliferation of primitive hematopoietic progenitors of mice in synergy with steel factor or the ligand for Flt3/Flk2. Blood. 1996 Dec 01; 88(11):4124-31. View abstract
  208. D'Andrea AD. Fanconi anaemia forges a novel pathway. Nat Genet. 1996 Nov; 14(3):240-2. View abstract
  209. Xia K, Mukhopadhyay NK, Inhorn RC, Barber DL, Rose PE, Lee RS, Narsimhan RP, D'Andrea AD, Griffin JD, Roberts TM. The cytokine-activated tyrosine kinase JAK2 activates Raf-1 in a p21ras-dependent manner. Proc Natl Acad Sci U S A. 1996 Oct 15; 93(21):11681-6. View abstract
  210. Bhattacharya S, Eckner R, Grossman S, Oldread E, Arany Z, D'Andrea A, Livingston DM. Cooperation of Stat2 and p300/CBP in signalling induced by interferon-alpha. Nature. 1996 Sep 26; 383(6598):344-7. View abstract
  211. Zhu Y, Pless M, Inhorn R, Mathey-Prevot B, D'Andrea AD. The murine DUB-1 gene is specifically induced by the betac subunit of interleukin-3 receptor. Mol Cell Biol. 1996 Sep; 16(9):4808-17. View abstract
  212. Kupfer GM, D'Andrea AD. The effect of the Fanconi anemia polypeptide, FAC, upon p53 induction and G2 checkpoint regulation. Blood. 1996 Aug 01; 88(3):1019-25. View abstract
  213. D'Andrea A, Chang C, Phillips JH, Lanier LL. Regulation of T cell lymphokine production by killer cell inhibitory receptor recognition of self HLA class I alleles. J Exp Med. 1996 Aug 01; 184(2):789-94. View abstract
  214. Shikama Y, Barber DL, D'Andrea AD, Sieff CA. A constitutively activated chimeric cytokine receptor confers factor-independent growth in hematopoietic cell lines. Blood. 1996 Jul 15; 88(2):455-64. View abstract
  215. Yamashita T, Wu N, Kupfer G, Corless C, Joenje H, Grompe M, D'Andrea AD. Clinical variability of Fanconi anemia (type C) results from expression of an amino terminal truncated Fanconi anemia complementation group C polypeptide with partial activity. Blood. 1996 May 15; 87(10):4424-32. View abstract
  216. Zhu Y, Carroll M, Papa FR, Hochstrasser M, D'Andrea AD. DUB-1, a deubiquitinating enzyme with growth-suppressing activity. Proc Natl Acad Sci U S A. 1996 Apr 16; 93(8):3275-9. View abstract
  217. D'Andrea A, Lanier LL. NKB1: a killer cell inhibitory receptor for class I HLA-B allotypes. Chem Immunol. 1996; 64:104-15. View abstract
  218. D'Andrea AD, Zhu Y. Cloning and functional analysis of erythropoietin-, interleukin-3- and thrombopoietin-inducible genes. Stem Cells. 1996; 14 Suppl 1:82-7. View abstract
  219. D'Andrea A, Chang C, Franz-Bacon K, McClanahan T, Phillips JH, Lanier LL. Molecular cloning of NKB1. A natural killer cell receptor for HLA-B allotypes. J Immunol. 1995 Sep 01; 155(5):2306-10. View abstract
  220. Carroll M, Zhu Y, D'Andrea AD. Erythropoietin-induced cellular differentiation requires prolongation of the G1 phase of the cell cycle. Proc Natl Acad Sci U S A. 1995 Mar 28; 92(7):2869-73. View abstract
  221. D'Andrea A, Ma X, Aste-Amezaga M, Paganin C, Trinchieri G. Stimulatory and inhibitory effects of interleukin (IL)-4 and IL-13 on the production of cytokines by human peripheral blood mononuclear cells: priming for IL-12 and tumor necrosis factor alpha production. J Exp Med. 1995 Feb 01; 181(2):537-46. View abstract
  222. D'Andrea AD. Hematopoietic growth factors and the regulation of differentiative decisions. Curr Opin Cell Biol. 1994 Dec; 6(6):804-8. View abstract
  223. Boussiotis VA, Barber DL, Nakarai T, Freeman GJ, Gribben JG, Bernstein GM, D'Andrea AD, Ritz J, Nadler LM. Prevention of T cell anergy by signaling through the gamma c chain of the IL-2 receptor. Science. 1994 Nov 11; 266(5187):1039-42. View abstract
  224. Barber DL, D'Andrea AD. Erythropoietin and interleukin-2 activate distinct JAK kinase family members. Mol Cell Biol. 1994 Oct; 14(10):6506-14. View abstract
  225. Fisher MJ, Prchal JF, Prchal JT, D'Andrea AD. Anti-erythropoietin (EPO) receptor monoclonal antibodies distinguish EPO-dependent and EPO-independent erythroid progenitors in polycythemia vera. Blood. 1994 Sep 15; 84(6):1982-91. View abstract
  226. Yamashita T, Barber DL, Zhu Y, Wu N, D'Andrea AD. The Fanconi anemia polypeptide FACC is localized to the cytoplasm. Proc Natl Acad Sci U S A. 1994 Jul 05; 91(14):6712-6. View abstract
  227. Carroll M, Mathey-Prevot B, D'Andrea A. Differentiation domains of the erythropoietin receptor. Proc Soc Exp Biol Med. 1994 Jul; 206(3):289-94. View abstract
  228. Aste-Amezaga M, D'Andrea A, Kubin M, Trinchieri G. Cooperation of natural killer cell stimulatory factor/interleukin-12 with other stimuli in the induction of cytokines and cytotoxic cell-associated molecules in human T and NK cells. Cell Immunol. 1994 Jul; 156(2):480-92. View abstract
  229. Sokol L, Prchal JF, D'Andrea A, Rado TA, Prchal JT. Mutation in the negative regulatory element of the erythropoietin receptor gene in a case of sporadic primary polycythemia. Exp Hematol. 1994 May; 22(5):447-53. View abstract
  230. Bessalle R, D'Andrea A, Fasman G. Refolding of the isolated extracellular domain of the erythropoietin receptor. Biochem Biophys Res Commun. 1994 Apr 15; 200(1):482-8. View abstract
  231. DeMartino J, Carroll M, Mathey-Prevot B, D'Andrea AD. Erythropoietin receptor contains both growth-promoting activity and differentiation-promoting activity. Ann N Y Acad Sci. 1994 Apr 15; 718:213-21; discussion 221-2. View abstract
  232. Barber DL, DeMartino JC, Showers MO, D'Andrea AD. A dominant negative erythropoietin (EPO) receptor inhibits EPO-dependent growth and blocks F-gp55-dependent transformation. Mol Cell Biol. 1994 Apr; 14(4):2257-65. View abstract
  233. Chehimi J, Starr SE, Frank I, D'Andrea A, Ma X, MacGregor RR, Sennelier J, Trinchieri G. Impaired interleukin 12 production in human immunodeficiency virus-infected patients. J Exp Med. 1994 Apr 01; 179(4):1361-6. View abstract
  234. D'Andrea AD. Cytokine receptors in congenital hematopoietic disease. N Engl J Med. 1994 Mar 24; 330(12):839-46. View abstract
  235. Zhu Y, D'Andrea AD. The molecular physiology of erythropoietin and the erythropoietin receptor. Curr Opin Hematol. 1994 Mar; 1(2):113-8. View abstract
  236. Liboi E, Carroll M, D'Andrea AD, Mathey-Prevot B. Erythropoietin receptor signals both proliferation and erythroid-specific differentiation. Proc Natl Acad Sci U S A. 1993 Dec 01; 90(23):11351-5. View abstract
  237. D'Andrea A, Aste-Amezaga M, Valiante NM, Ma X, Kubin M, Trinchieri G. Interleukin 10 (IL-10) inhibits human lymphocyte interferon gamma-production by suppressing natural killer cell stimulatory factor/IL-12 synthesis in accessory cells. J Exp Med. 1993 Sep 01; 178(3):1041-8. View abstract
  238. D'Andrea AD, Rup BJ, Fisher MJ, Jones S. Anti-erythropoietin receptor (EPO-R) monoclonal antibodies inhibit erythropoietin binding and neutralize bioactivity. Blood. 1993 Jul 01; 82(1):46-52. View abstract
  239. Baron P, Constantin G, D'Andrea A, Ponzin D, Scarpini E, Scarlato G, Trinchieri G, Rossi F, Cassatella MA. Production of tumor necrosis factor and other proinflammatory cytokines by human mononuclear phagocytes stimulated with myelin P2 protein. Proc Natl Acad Sci U S A. 1993 May 15; 90(10):4414-8. View abstract
  240. Galson DL, Hensold JO, Bishop TR, Schalling M, D'Andrea AD, Jones C, Auron PE, Housman DE. Mouse beta-globin DNA-binding protein B1 is identical to a proto-oncogene, the transcription factor Spi-1/PU.1, and is restricted in expression to hematopoietic cells and the testis. Mol Cell Biol. 1993 May; 13(5):2929-41. View abstract
  241. Showers MO, DeMartino JC, Saito Y, D'Andrea AD. Fusion of the erythropoietin receptor and the Friend spleen focus-forming virus gp55 glycoprotein transforms a factor-dependent hematopoietic cell line. Mol Cell Biol. 1993 Feb; 13(2):739-48. View abstract
  242. Showers MO, Moreau JF, Linnekin D, Druker B, D'Andrea AD. Activation of the erythropoietin receptor by the Friend spleen focus-forming virus gp55 glycoprotein induces constitutive protein tyrosine phosphorylation. Blood. 1992 Dec 15; 80(12):3070-8. View abstract
  243. Perussia B, Chan SH, D'Andrea A, Tsuji K, Santoli D, Pospisil M, Young D, Wolf SF, Trinchieri G. Natural killer (NK) cell stimulatory factor or IL-12 has differential effects on the proliferation of TCR-alpha beta+, TCR-gamma delta+ T lymphocytes, and NK cells. J Immunol. 1992 Dec 01; 149(11):3495-502. View abstract
  244. D'Andrea A, Rengaraju M, Valiante NM, Chehimi J, Kubin M, Aste M, Chan SH, Kobayashi M, Young D, Nickbarg E, et al. Production of natural killer cell stimulatory factor (interleukin 12) by peripheral blood mononuclear cells. J Exp Med. 1992 Nov 01; 176(5):1387-98. View abstract
  245. Barber DL, D'Andrea AD. The erythropoietin receptor and the molecular basis of signal transduction. Semin Hematol. 1992 Oct; 29(4):293-304. View abstract
  246. D'Andrea AD, Moreau JF, Showers MO. Molecular mimicry of erythropoietin by the spleen focus-forming virus gp55 glycoprotein: the first stage of Friend virus-induced erythroleukemia. Biochim Biophys Acta. 1992 Sep 14; 1114(1):31-41. View abstract
  247. Linnekin D, Evans GA, D'Andrea A, Farrar WL. Association of the erythropoietin receptor with protein tyrosine kinase activity. Proc Natl Acad Sci U S A. 1992 Jul 15; 89(14):6237-41. View abstract
  248. Zon LI, Moreau JF, Koo JW, Mathey-Prevot B, D'Andrea AD. The erythropoietin receptor transmembrane region is necessary for activation by the Friend spleen focus-forming virus gp55 glycoprotein. Mol Cell Biol. 1992 Jul; 12(7):2949-57. View abstract
  249. Emanuel PD, Eaves CJ, Broudy VC, Papayannopoulou T, Moore MR, D'Andrea AD, Prchal JF, Eaves AC, Prchal JT. Familial and congenital polycythemia in three unrelated families. Blood. 1992 Jun 01; 79(11):3019-30. View abstract
  250. Showers MO, D'Andrea AD. Subunit structure and transmembrane signaling of the erythropoietin receptor. Int Rev Cytol. 1992; 137B:99-120. View abstract
  251. D'Andrea AD. The interaction of the erythropoietin receptor and gp55. Cancer Surv. 1992; 15:19-36. View abstract
  252. Migliaccio AR, Migliaccio G, D'Andrea A, Baiocchi M, Crotta S, Nicolis S, Ottolenghi S, Adamson JW. Response to erythropoietin in erythroid subclones of the factor-dependent cell line 32D is determined by translocation of the erythropoietin receptor to the cell surface. Proc Natl Acad Sci U S A. 1991 Dec 15; 88(24):11086-90. View abstract
  253. Miura O, D'Andrea A, Kabat D, Ihle JN. Induction of tyrosine phosphorylation by the erythropoietin receptor correlates with mitogenesis. Mol Cell Biol. 1991 Oct; 11(10):4895-902. View abstract
  254. D'Andrea AD, Jones SS. Activation of the erythropoietin receptor in stable lymphoid and myeloid transfectants. Semin Hematol. 1991 Apr; 28(2):152-7. View abstract
  255. D'Andrea AD, Yoshimura A, Youssoufian H, Zon LI, Koo JW, Lodish HF. The cytoplasmic region of the erythropoietin receptor contains nonoverlapping positive and negative growth-regulatory domains. Mol Cell Biol. 1991 Apr; 11(4):1980-7. View abstract
  256. D'Andrea AD, Koo JW. Structure and function of the erythropoietin receptor in stable erythropoietin-dependent transfectants. Contrib Nephrol. 1991; 88:48-56; discussion 57-8. View abstract
  257. Budarf M, Huebner K, Emanuel B, Croce CM, Copeland NG, Jenkins NA, D'Andrea AD. Assignment of the erythropoietin receptor (EPOR) gene to mouse chromosome 9 and human chromosome 19. Genomics. 1990 Nov; 8(3):575-8. View abstract
  258. D'Andrea AD, Zon LI. Erythropoietin receptor. Subunit structure and activation. J Clin Invest. 1990 Sep; 86(3):681-7. View abstract
  259. D'Andrea AD, Fasman GD, Lodish HF. A new hematopoietic growth factor receptor superfamily: structural features and implications for signal transduction. Curr Opin Cell Biol. 1990 Aug; 2(4):648-51. View abstract
  260. Jones SS, D'Andrea AD, Haines LL, Wong GG. Human erythropoietin receptor: cloning, expression, and biologic characterization. Blood. 1990 Jul 01; 76(1):31-5. View abstract
  261. Youssoufian H, Zon LI, Orkin SH, D'Andrea AD, Lodish HF. Structure and transcription of the mouse erythropoietin receptor gene. Mol Cell Biol. 1990 Jul; 10(7):3675-82. View abstract
  262. Yoshimura A, D'Andrea AD, Lodish HF. Friend spleen focus-forming virus glycoprotein gp55 interacts with the erythropoietin receptor in the endoplasmic reticulum and affects receptor metabolism. Proc Natl Acad Sci U S A. 1990 Jun; 87(11):4139-43. View abstract
  263. Li JP, D'Andrea AD, Lodish HF, Baltimore D. Activation of cell growth by binding of Friend spleen focus-forming virus gp55 glycoprotein to the erythropoietin receptor. Nature. 1990 Feb 22; 343(6260):762-4. View abstract
  264. D'Andrea AD, Szklut PJ, Lodish HF, Alderman EM. Inhibition of receptor binding and neutralization of bioactivity by anti-erythropoietin monoclonal antibodies. Blood. 1990 Feb 15; 75(4):874-80. View abstract
  265. D'Andrea AD, Fasman GD, Zon LI, Li JP, Lodish HF. Structure of the erythropoietin receptor in stable fibroblast transfectants. Prog Clin Biol Res. 1990; 352:153-9. View abstract
  266. D'Andrea A, Fasman G, Wong G, Lodish H. Erythropoietin receptor: cloning strategy and structural features. Int J Cell Cloning. 1990 Jan; 8 Suppl 1:173-80. View abstract
  267. D'Andrea AD, Fasman GD, Lodish HF. Erythropoietin receptor and interleukin-2 receptor beta chain: a new receptor family. Cell. 1989 Sep 22; 58(6):1023-4. View abstract
  268. Tsai SF, Martin DI, Zon LI, D'Andrea AD, Wong GG, Orkin SH. Cloning of cDNA for the major DNA-binding protein of the erythroid lineage through expression in mammalian cells. Nature. 1989 Jun 08; 339(6224):446-51. View abstract
  269. D'Andrea AD, Lodish HF, Wong GG. Expression cloning of the murine erythropoietin receptor. Cell. 1989 Apr 21; 57(2):277-85. View abstract
  270. Bellah R, D'Andrea A, Darillis E, Fellows KE. The association of congenital neuroblastoma and congenital heart disease. Is there a common embryologic basis? Pediatr Radiol. 1989; 19(2):119-21. View abstract
  271. D'Andrea AD, Bayever E, Haines KM, Wilmott RW, Polin RA, August CS, Douglas SD. Serial evaluation of lymphocyte function in bone marrow-grafted patients. Diagn Immunol. 1986; 4(6):281-7. View abstract
  272. Latt SA, Schreck RR, D'Andrea A, Kaiser TN, Schlesinger F, Lester S, Sakai K. Detection, significance, and mechanism of sister chromatid exchange formation: past experiments, current concepts, future challenges. Basic Life Sci. 1984; 29 Pt A:11-40. View abstract
  273. D'Andrea AD, Tantravahi U, Lalande M, Perle MA, Latt SA. High resolution analysis of the timing of replication of specific DNA sequences during S phase of mammalian cells. Nucleic Acids Res. 1983 Jul 25; 11(14):4753-74. View abstract
  274. Haseltine WA, Lindan CP, D'Andrea AD, Johnsrud L. The use of DNA fragments of defined sequence for the study of DNA damage and repair. Methods Enzymol. 1980; 65(1):235-48. View abstract