Laurie E.  Cohen

Laurie Cohen, MD

Clinical Chief, Division of Endocrinology

Assistant Professor of Pediatrics

    Contact: 617-355-7476
  • Fax: 617-730-0194

Medical Services

Specialties

  • Neuroendocrinology
  • Growth Issues and Disorders
  • Endocrine Sequelae of Cancer and its Treatments

Departments

  • Endocrinology
  • Medicine

Programs

  • Neuroendocrinology Program
  • Brain Tumor Center
  • Bone Marrow Failure Program
To schedule an appointment: Call 617-355-7476 or Request an Appointment

Experience and Education

Education

MD

Cornell University Medical College, 1988

New York, NY

Undergraduate School, Bachelor of Arts

University of Pennsylvania, 1984

Philadelphia, PA

Certifications

  • Pediatric Endocrinology

Publications

Publications powered by Harvard Catalyst Profiles
  1. Cohen LE. Update on childhood craniopharyngiomas. Curr Opin Endocrinol Diabetes Obes. 2016 Aug; 23(4):339-44.
  2. Christiansen JS, Backeljauw PF, Bidlingmaier M, Biller BM, Boguszewski MC, Casanueva FF, Chanson P, Chatelain P, Choong CS, Clemmons DR, Cohen LE, Cohen P, Frystyk J, Grimberg A, Hasegawa Y, Haymond MW, Ho K, Hoffman AR, Holly JM, Horikawa R, Höybye C, Jorgensen JO, Johannsson G, Juul A, Katznelson L, Kopchick JJ, Lee KO, Lee KW, Luo X, Melmed S, Miller BS, Misra M, Popovic V, Rosenfeld RG, Ross J, Ross RJ, Saenger P, Strasburger CJ, Thorner MO, Werner H, Yuen K. Growth Hormone Research Society perspective on the development of long-acting growth hormone preparations. Eur J Endocrinol. 2016 Jun; 174(6):C1-8.
  3. Nahata L, Yu RN, Paltiel HJ, Chow JS, Logvinenko T, Rosoklija I, Cohen LE. Sperm Retrieval in Adolescents and Young Adults with Klinefelter Syndrome: A Prospective, Pilot Study. J Pediatr. 2016 Mar; 170:260-5.e1-2.
  4. Nahata L, Yu RN, Bhasin S, Cohen LE. Management of testosterone therapy in adolescents and young men with hypogonadism: are we following adult clinical practice guidelines? J Pediatr Endocrinol Metab. 2015 May; 28(5-6):635-40.
  5. Cohen LE. Idiopathic short stature: a clinical review. JAMA. 2014 May 7; 311(17):1787-96.
  6. Cohen LE. JAMA patient page. Short stature. JAMA. 2014 May 7; 311(17):1822.
  7. Lee JJ, Mitchell PD, Hood HC, Grand RJ, Cohen LE. Potential role of IGF-1 z score to predict permanent linear growth impairment in children with IBD. J Pediatr Gastroenterol Nutr. 2014 Apr; 58(4):472-6.
  8. Nahata L, Rosoklija I, Yu RN, Cohen LE. Klinefelter syndrome: are we missing opportunities for early detection? Clin Pediatr (Phila). 2013 Oct; 52(10):936-41.
  9. Wassner AJ, Cohen LE, Hechter E, Dauber A. Isolated central hypothyroidism in young siblings as a manifestation of PROP1 deficiency: clinical impact of whole exome sequencing. Horm Res Paediatr. 2013; 79(6):379-86.
  10. Cohen LE. GLI2 mutations as a cause of hypopituitarism. Pediatr Endocrinol Rev. 2012 Aug; 9(4):706-9.
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  12. Kenney LB, Cohen LE, Shnorhavorian M, Metzger ML, Lockart B, Hijiya N, Duffey-Lind E, Constine L, Green D, Meacham L. Male reproductive health after childhood, adolescent, and young adult cancers: a report from the Children's Oncology Group. J Clin Oncol. 2012 Sep 20; 30(27):3408-16.
  13. Nahata L, Cohen LE, Lehmann LE, Yu RN. Semen analysis in adolescent cancer patients prior to bone marrow transplantation: when is it too late for fertility preservation? Pediatr Blood Cancer. 2013 Jan; 60(1):129-32.
  14. Nahata L, Cohen LE, Yu RN. Barriers to fertility preservation in male adolescents with cancer: it's time for a multidisciplinary approach that includes urologists. Urology. 2012 Jun; 79(6):1206-9.
  15. Manley PE, McKendrick K, McGillicudy M, Chi SN, Kieran MW, Cohen LE, Kothare S, Michael Scott R, Goumnerova LC, Sun P, London W, Marcus KJ, Pomeroy SL, Ullrich NJ. Sleep dysfunction in long term survivors of craniopharyngioma. J Neurooncol. 2012 Jul; 108(3):543-9.
  16. Cohen LE. Genetic disorders of the pituitary. Curr Opin Endocrinol Diabetes Obes. 2012 Feb; 19(1):33-9.
  17. Hood HC, Cohen LE, Lee JJ. Late adolescent linear growth pattern in pediatric-onset inflammatory bowel disease. J Pediatr Gastroenterol Nutr. 2011 Sep; 53(3):246-9.
  18. Cohen LE, Gordon JH, Popovsky EY, Sainath NN, Feldman HA, Kieran MW, Gordon CM. Bone density in post-pubertal adolescent survivors of childhood brain tumors. Pediatr Blood Cancer. 2012 Jun; 58(6):959-63.
  19. Winkfield KM, Tsai HK, Yao X, Larson E, Neuberg D, Pomeroy SL, Ullrich NJ, Cohen LE, Kieran MW, Scott RM, Goumnerova LC, Marcus KJ. Long-term clinical outcomes following treatment of childhood craniopharyngioma. Pediatr Blood Cancer. 2011 Jul 1; 56(7):1120-6.
  20. Topor LS, Feldman HA, Bauchner H, Cohen LE. Variation in methods of predicting adult height for children with idiopathic short stature. Pediatrics. 2010 Nov; 126(5):938-44.
  21. Masoud MI, Masoud I, Kent RL, Gowharji N, Hassan AH, Cohen LE. Relationship between blood-spot insulin-like growth factor 1 levels and hand-wrist assessment of skeletal maturity. Am J Orthod Dentofacial Orthop. 2009 Jul; 136(1):59-64.
  22. Fofanova-Gambetti OV, Hwa V, Kirsch S, Pihoker C, Chiu HK, Högler W, Cohen LE, Jacobsen C, Derr MA, Rosenfeld RG. Three novel IGFALS gene mutations resulting in total ALS and severe circulating IGF-I/IGFBP-3 deficiency in children of different ethnic origins. Horm Res. 2009; 71(2):100-10.
  23. Jacobsen CM, Cohen LE. Short stature in a phenotypic male caused by mixed gonadal dysgenesis. Nat Clin Pract Endocrinol Metab. 2008 Sep; 4(9):524-8.
  24. Cohen LE. Cancer treatment and the ovary: the effects of chemotherapy and radiation. Ann N Y Acad Sci. 2008; 1135:123-5.
  25. Dorsey MJ, Cohen LE, Phipatanakul W, Denufrio D, Schneider LC. Assessment of adrenal suppression in children with asthma treated with inhaled corticosteroids: use of dehydroepiandrosterone sulfate as a screening test. Ann Allergy Asthma Immunol. 2006 Aug; 97(2):182-6.
  26. Cohen LE. Endocrine late effects of cancer treatment. Endocrinol Metab Clin North Am. 2005 Sep; 34(3):769-89, xi.
  27. Fleischman A, Brue C, Poussaint TY, Kieran M, Pomeroy SL, Goumnerova L, Scott RM, Cohen LE. Diencephalic syndrome: a cause of failure to thrive and a model of partial growth hormone resistance. Pediatrics. 2005 Jun; 115(6):e742-8.
  28. Cohen LE. . Endocrine Sequelae of Therapy for Cancer in Children. Endo Metab Clin NA. 2005.
  29. Cohen LE. . “Endocrine Sequelae in Cancer Survivors”. Syllabus for A Current Review of Endocrinology, Serono Symposium, San Diego, CA. 2005.
  30. Dalton VK, Rue M, Silverman LB, Gelber RD, Asselin BL, Barr RD, Clavell LA, Hurwitz CA, Moghrabi A, Samson Y, Schorin M, Tarbell NJ, Sallan SE, Cohen LE. Height and weight in children treated for acute lymphoblastic leukemia: relationship to CNS treatment. J Clin Oncol. 2003 Aug 1; 21(15):2953-60.
  31. Hashimoto Y, Cisternino M, Cohen LE. A novel nonsense mutation in the Pit-1 gene: evidence for a gene dosage effect. J Clin Endocrinol Metab. 2003 Mar; 88(3):1241-7.
  32. Cohen LE. Endocrine late effects of cancer treatment. Curr Opin Pediatr. 2003 Feb; 15(1):3-9.
  33. Botero D, Evliyaoglu O, Cohen LE. . Hypopituitarism . Clinical Management of Pediatric Endocrine Disorders.Radovick S and MacGillivray M, editors. 2003; 3-36.
  34. Cohen LE. . “Molecular Basis of Hypopituitarism”. Syllabus for A Current Review of Endocrinology, Serono Symposium, Seattle, WA. 2003.
  35. Cohen LE, Radovick S. Other transcription factors and hypopituitarism. Rev Endocr Metab Disord. 2002 Dec; 3(4):301-11.
  36. Cohen LE, Radovick S. Molecular basis of combined pituitary hormone deficiencies. Endocr Rev. 2002 Aug; 23(4):431-42.
  37. Narayan M, Cohen L, Goumnerova L. Eating Dysfunction Following Endoscopic Third Ventriculostomy. American Association of Neurological Surgery. 2002.
  38. Carpentieri SC, Waber DP, Scott RM, Goumnerova LC, Kieran MW, Cohen LE, Kim F, Billett AL, Tarbell NJ, Pomeroy SL. Memory deficits among children with craniopharyngiomas. Neurosurgery. 2001 Nov; 49(5):1053-7; discussion 1057-8.
  39. Samuels RC, Cohen LE. . Understanding Growth Patterns. Contemporary Pediatrics. 2001; 18:94-122.
  40. Cohen LE, Knight JR. Constitutional Short Stature: Timmy and the “Big Kids”. In: Knight JR and Emans SJ, editors. Bright Futures Case Studies for Primary Care Clinicians, A Guide to the Case Teaching Method; and Growth in Children and Adolescents. U.S. Department of Health and Human Services, Health Resources and Services Administration, Maternal and Child Health Bureau. 2001.
  41. Cohen LE. Understanding Growth: Normal vs. Abnormal Patterns. In: Knight JR and Emans SJ, editors. Bright Futures Case Studies for Primary Care Clinicians, A Guide to the Case Teaching Method; and Growth in Children and Adolescents. U.S. Department of Health and Human Services, Health Resources and Services Administration, Maternal and Child Health Bureau. 2001.
  42. Cohen LE. Genetic regulation of the embryology of the pituitary gland and somatotrophs. Endocrine. 2000 Apr; 12(2):99-106.
  43. Cohen LE, Radovick S, Wondisford FE. . Transcription Factors and Hypopituitarism. TEM. 1999; 10:326-332.
  44. Radovick S, Cohen LE. . “Anterior Pituitary Hormone Deficiencies”. Syllabus for A Current Review of Endocrinology, Serono Symposium, New Orleans, LA. 1999.
  45. Radovick S, Cohen LE, Wondisford FE. The molecular basis of hypopituitarism. Horm Res. 1998; 49 Suppl 1:30-6.
  46. Hamilton J, Chitayat D, Blaser S, Cohen LE, Phillips III JA, Daneman D. . Familial Growth Hormone Deficiency Associated with MRI Abnormalities. Amer J Human Genetics. 1998; 80:128-132.
  47. Medlock MD, Madsen JR, Barnes PD, Anthony DS, Cohen LE, Scott RM. Optic chiasm astrocytomas of childhood. 1. Long-term follow-up. Pediatr Neurosurg. 1997 Sep; 27(3):121-8.
  48. Cohen LE, Wondisford FE, Radovick S. . Molecular Aspects of Hormone Deficiency Caused by Pit-1 Gene Mutations. Advances in Molecular and Cellular Endocrinology. LeRoith D, editor. 1997; 1:31-50.
  49. Poussaint TY, Barnes PD, Nichols K, Anthony D, Cohen LE, Tarbell NJ, Goumnerova L. Diencephalic syndrome: Clinical Features and Imaging Findings. Amer J of Neuroradiology. 1997; 18:1499-1505.
  50. Cohen LE, Wondisford FE, Radovick S. . Role of Pit-1 on the Expression of Growth Hormone, Prolactin, and Thyrotropin. Endo Metab Clin NA. 1996; 25:523-540.
  51. Cohen LE. Controversies in Clinical and Surgical Endocrinology. Short Stature. In: Herrera MF, Lerman I, editors. 1996.
  52. Cohen LE, Wondisford FE, Salvatoni A, Maghnie M, Brucker-Davis F, Weintraub BD, Radovick S. A "hot spot" in the Pit-1 gene responsible for combined pituitary hormone deficiency: clinical and molecular correlates. J Clin Endocrinol Metab. 1995 Feb; 80(2):679-84.
  53. Cohen LE, Hashimoto Y, Zanger K, Wondisford F, Radovick S. CREB-independent regulation by CBP is a novel mechanism of human growth hormone gene expression. J Clin Invest. 1999 Oct; 104(8):1123-30.
  54. Zanger K, Cohen LE, Hashimoto K, Radovick S, Wondisford FE. A novel mechanism for cyclic adenosine 3',5'-monophosphate regulation of gene expression by CREB-binding protein. Mol Endocrinol. 1999 Feb; 13(2):268-75.
  55. Masoud M, Masoud I, Kent RL, Gowharji N, Cohen LE. Assessing skeletal maturity by using blood spot insulin-like growth factor I (IGF-I) testing. Am J Orthod Dentofacial Orthop. 2008 Aug; 134(2):209-16.
  56. Cohen LE, Zanger K, Brue T, Wondisford FE, Radovick S. Defective retinoic acid regulation of the Pit-1 gene enhancer: a novel mechanism of combined pituitary hormone deficiency. Mol Endocrinol. 1999 Mar; 13(3):476-84.
  57. Cohen RN, Cohen LE, Botero D, Yu C, Sagar A, Jurkiewicz M, Radovick S. Enhanced repression by HESX1 as a cause of hypopituitarism and septooptic dysplasia. J Clin Endocrinol Metab. 2003 Oct; 88(10):4832-9.
  58. Hashimoto K, Zanger K, Hollenberg AN, Cohen LE, Radovick S, Wondisford FE. cAMP response element-binding protein-binding protein mediates thyrotropin-releasing hormone signaling on thyrotropin subunit genes. J Biol Chem. 2000 Oct 27; 275(43):33365-72.
  59. Robison NJ, Prabhu SP, Sun P, Chi SN, Kieran MW, Manley PE, Cohen LE, Goumnerova L, Smith ER, Scott RM, London WB, Ullrich NJ. Predictors of neoplastic disease in children with isolated pituitary stalk thickening. Pediatr Blood Cancer. 2013 Oct; 60(10):1630-5.
  60. Nahata L, Yu RN, Cohen LE. Klinefelter syndrome: fertility considerations and gaps in knowledge. Transl Pediatr. 2016 Jul; 5(3):183-184.
  61. Grimberg A, DiVall SA, Polychronakos C, Allen DB, Cohen LE, Quintos JB, Rossi WC, Feudtner C, Murad MH. Guidelines for Growth Hormone and Insulin-Like Growth Factor-I Treatment in Children and Adolescents: Growth Hormone Deficiency, Idiopathic Short Stature, and Primary Insulin-Like Growth Factor-I Deficiency. Horm Res Paediatr. 2016 Nov 25.
To schedule an appointment: Call 617-355-7476 or Request an Appointment

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