MEDICAL SERVICES

Specialties

Departments

Languages

EDUCATION

Medical School

  • The Victor Babes University of Medicine , Timisoara , Romania

Graduate Degree

Anatomic and Clinical Pathology
  • University of Texas , Houston , TX

Fellowship

Pediatric Pathology
  • Boston Children's Hospital , Boston , MA

Fellowship

Neuropathology
  • University of California at San Francisco , San Francisco , CA

CERTIFICATIONS

  • American Board of Pathology, Anatomic Clinical Pathology
  • American Board of Pathology, Anatomic Neuropathology
  • Anatomic and Clinical Pathology_ Pediatric Pathology

PUBLICATIONS

Publications powered by Harvard Catalyst Profiles

  1. Alexandrescu S, Paulson V, Dubuc A, Ligon A, Lidov HG. PHOX2B Is A Reliable Immunomarker in Distinguishing Peripheral Neuroblastic Tumors From CNS Embryonal Tumors. Histopathology. 2018 May 14. View abstract
  2. Shannon ML, Fame RM, Chau KF, Dani N, Calicchio ML, Géléoc GS, Lidov HGW, Alexandrescu S, Lehtinen MK. Mice Expressing Myc in Neural Precursors Develop Choroid Plexus and Ciliary Body Tumors. Am J Pathol. 2018 Jun; 188(6):1334-1344. View abstract
  3. Jones DTW, Kieran MW, Bouffet E, Alexandrescu S, Bandopadhayay P, Bornhorst M, Ellison D, Fangusaro J, Fisher MJ, Foreman N, Fouladi M, Hargrave D, Hawkins C, Jabado N, Massimino M, Mueller S, Perilongo G, Schouten van Meeteren AYN, Tabori U, Warren K, Waanders AJ, Walker D, Weiss W, Witt O, Wright K, Zhu Y, Bowers DC, Pfister SM, Packer RJ. Pediatric low-grade gliomas: next biologically driven steps. Neuro Oncol. 2018 Jan 22; 20(2):160-173. View abstract
  4. Dixit A, Alexandrescu S, Boyer D, Graf EH, Vargas SO, Silverman M. Mycoplasma hominis Empyema in an 18-Year-old Stem Cell and Lung Transplant Recipient: Case Report and Review of the Literature. J Pediatric Infect Dis Soc. 2017 Nov 24; 6(4):e173-e176. View abstract
  5. Helgager J, Lidov HG, Mahadevan NR, Kieran MW, Ligon KL, Alexandrescu S. A novel GIT2-BRAF fusion in pilocytic astrocytoma. Diagn Pathol. 2017 Nov 15; 12(1):82. View abstract
  6. Lai PMR, Zaazoue MA, Francois R, Dupervil DG, Berkowitz AL, Alexandrescu S, Proctor MR. Neurenteric cyst at the dorsal craniocervical junction in a child: Case report. J Clin Neurosci. 2018 Feb; 48:86-89. View abstract
  7. Karageorgiou E, Naasan G, Pleasure SJ, Alexandrescu S, Gelfand JM, Tammewar G, Miller BL, Rabinovici GD, Grinberg LT. Focal cerebral ß-amyloid angiopathy: A distinct clinicopathologic presentation. Neurol Clin Pract. 2017 Oct; 7(5):444-448. View abstract
  8. Wahl M, Chang SM, Phillips JJ, Molinaro AM, Costello JF, Mazor T, Alexandrescu S, Lupo JM, Nelson SJ, Berger M, Prados M, Taylor JW, Butowski N, Clarke JL, Haas-Kogan D. Probing the phosphatidylinositol 3-kinase/mammalian target of rapamycin pathway in gliomas: A phase 2 study of everolimus for recurrent adult low-grade gliomas. Cancer. 2017 Dec 01; 123(23):4631-4639. View abstract
  9. Ramkissoon SH, Bandopadhayay P, Hwang J, Ramkissoon LA, Greenwald NF, Schumacher SE, O'Rourke R, Pinches N, Ho P, Malkin H, Sinai C, Filbin M, Plant A, Bi WL, Chang MS, Yang E, Wright KD, Manley PE, Ducar M, Alexandrescu S, Lidov H, Delalle I, Goumnerova LC, Church AJ, Janeway KA, Harris MH, MacConaill LE, Folkerth RD, Lindeman NI, Stiles CD, Kieran MW, Ligon AH, Santagata S, Dubuc AM, Chi SN, Beroukhim R, Ligon KL. Clinical targeted exome-based sequencing in combination with genome-wide copy number profiling: precision medicine analysis of 203 pediatric brain tumors. Neuro Oncol. 2017 Jul 01; 19(7):986-996. View abstract
  10. Bale TA, Oviedo A, Kozakewich H, Giannini C, Davineni PK, Ligon K, Alexandrescu S. Intracranial myxoid mesenchymal tumors with EWSR1-CREB family gene fusions: myxoid variant of angiomatoid fibrous histiocytoma or novel entity? Brain Pathol. 2018 03; 28(2):183-191. View abstract
  11. Karageorgiou E, Naasan G, Pleasure SJ, Alexandrescu S, Gelfand JM, Tammewar G, Miller BL, Rabinovici GD, Grinberg LT. Focal cerebral beta-amyloid angiopathy. A distinct clinicopathologic presentation. Neurology Clinical Practice. 2017. View abstract
  12. Alexandrescu S, Akhavanfard S, Harris MH, Vargas SO. Clinical, Pathologic, and Genetic Features of Wilms Tumors With WTX Gene Mutation. Pediatr Dev Pathol. 2017 Mar-Apr; 20(2):105-111. View abstract
  13. Alexandrescu S, Tucker S. Diagnostic Histopathology. A review of molecular alterations with clinical impact in adult and paediatric gliomas. 2016; 22(11):439-446. View abstract
  14. Tucker S, Alexandrescu S. Diagnostic Histopathology. Updates and review of neoplastic paediatric neuropathology. 2016; 22(11):431–438. View abstract
  15. Huang L, Couto JA, Pinto A, Alexandrescu S, Madsen JR, Greene AK, Sahin M, Bischoff J. Somatic GNAQ Mutation is Enriched in Brain Endothelial Cells in Sturge-Weber Syndrome. Pediatr Neurol. 2017 Feb; 67:59-63. View abstract
  16. Alexandrescu S, Akhavanfard S, Harris MH, Vargas SO. Clinical, pathologic, and genetic features of Wilms tumors with WTX gene mutation. Pediatr Dev Pathol. 2016 Jan 04. View abstract
  17. Alexandrescu S, Korshunov A, Lai SH, Dabiri S, Patil S, Li R, Shih CS, Bonnin JM, Baker JA, Du E, Scharnhorst DW, Samuel D, Ellison DW, Perry A. Epithelioid Glioblastomas and Anaplastic Epithelioid Pleomorphic Xanthoastrocytomas--Same Entity or First Cousins? Brain Pathol. 2016 Mar; 26(2):215-23. View abstract
  18. Alexandrescu S, Orengo JP, Toossi S, Perry A, Treseler P, Hess C, Margeta M. CNS intravascular large cell lymphoma in a patient with autoimmune hemolytic anemia. Neuropathology. 2015 Apr; 35(2):170-4. View abstract
  19. Senniappan S, Alexandrescu S, Tatevian N, Shah P, Arya V, Flanagan S, Ellard S, Rampling D, Ashworth M, Brown RE, Hussain K. Sirolimus therapy in infants with severe hyperinsulinemic hypoglycemia. N Engl J Med. 2014 Mar 20; 370(12):1131-7. View abstract
  20. Alexandrescu S, Rosenberg H, Tatevian N. Role of calretinin immunohistochemical stain in evaluation of Hirschsprung disease: an institutional experience. Int J Clin Exp Pathol. 2013; 6(12):2955-61. View abstract
  21. Alexandrescu S, Tatevian N, Czerniak BA, Covinsky MH, Burns NK, Brown RE. Morphoproteomics provides support for TGF-ß pathway signaling in the osteoclastogenesis and immune dysregulation of osteolytic Langerhans cell histiocytosis. Int J Clin Exp Pathol. 2012; 5(6):503-11. View abstract
  22. Hrehoret D, Alexandrescu S, Grigorie R, Herlea V, Anghel R, Popescu I. Intrahepatic cholangiocarcinoma--a rare indication for liver transplantation. Case report and review of the literature. Chirurgia (Bucur). 2012 Mar-Apr; 107(2):237-42. View abstract
  23. Alexandrescu S, Brown RE, Tandon N, Bhattacharjee MB. Neuron precursor features of spindle cell oncocytoma of adenohypophysis. Ann Clin Lab Sci. 2012; 42(2):123-9. View abstract
  24. Sargsyan Z, Higgins C, Alexandrescu S, Ott DA, Jain SK. Acute promyelocytic leukemia as a cause of intracoronary drug-eluting-stent thrombosis. Tex Heart Inst J. 2012; 39(3):416-9. View abstract
  25. Alexandrescu S, Tatevian N, Olutoye O, Brown RE. Persistent hyperinsulinemic hypoglycemia of infancy: constitutive activation of the mTOR pathway with associated exocrine-islet transdifferentiation and therapeutic implications. Int J Clin Exp Pathol. 2010 Aug 08; 3(7):691-705. View abstract
  26. Guo S, Kowalewska J, Wietecha TA, Iyoda M, Wang L, Yi K, Spencer M, Banas M, Alexandrescu S, Hudkins KL, Alpers CE. Renin-angiotensin system blockade is renoprotective in immune complex-mediated glomerulonephritis. J Am Soc Nephrol. 2008 Jun; 19(6):1168-76. View abstract