Vein of Galen Malformation Research and Clinical Trials in Children

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Contact the Cerebrovascular Surgery and Interventions Center

3D model of Vein of Galen 

3D printed model of Vein of Galen.

The Cerebrovascular Surgery and Interventions Center at Boston Children’s Hospital conducts ongoing research to better understand vein of Galen malformations. This work may pave the way for more precise diagnosis of VOGM and, in the future, more effective ways to close off the VOGM while preserving normal blood flow to the brain. We track our experience in a comprehensive patient database, allowing us to evaluate and compare techniques and improve our quality of care.

3D printing to model brain and vascular anatomy

Precision 3D models of VOGM—based on data from patients’ own brain scans—are allowing neurointerventionalists at Boston Children’s to plan and rehearse maneuvers in advance. The models are made by the Cerebrovascular Surgery and Interventions Center in collaboration with Peter Weinstock, MD, PhD, of the Simulator Program at Boston Children’s, using special digitally guided printers that lay down different types of molten plastic. Read more.

Refining VOGM procedures

A variety of novel techniques developed and trialed at Boston Children’s has allowed safe use of catheters and endovascular devices in infants’ tiny vessels. We also successfully adapted Onyx, an improved material used to treat cerebrovascular disease in adults, to VOGMs and other brain vascular malformations in children. We have an unparalleled safety record in treating children with this condition.

Limiting radiation exposure during neurointerventions

New techniques have dramatically improved safety and reduced children’s radiation exposure during neurointerventions. Working closely with fluoroscopy equipment vendors to adjust and optimize technical factors, we have demonstrated that it is possible to achieve high-quality imaging at low radiation doses.

See a list of our selected publications on cerebrovascular disease.

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- Sandra L. Fenwick, President and CEO

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