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A hemangioma is a benign (noncancerous) tumor formed by an abnormally dense group of endothelial cells (the cells that normally line the blood vessels). The exact cause remains unknown.
Most vascular malformations are sporadic (occurring by chance), though some are inherited in a family as an autosomal dominant trait. Autosomal dominant means that one gene is necessary to express the condition, and the gene is passed from parent to child with a 50/50 risk for each pregnancy. Males and females are equally affected and there is great variability in expression of the gene. In other words, a parent may unknowingly have had a hemangioma because it faded, but your child is more severely affected. The family may not come to the attention of a geneticist until the birth of the child with a more severe condition.
There are several types of vascular malformations:
• Capillary (port wine stains) always present at birth as pink or purple skin patches
• Venous often confused with a hemangioma, these malformations are soft to the touch and the color disappears
when compressed. They are most commonly found on the jaw, cheek, tongue and lips
• Lymphatic malformations form when excess fluid accumulates within the lymphatic vessels
• Arteriovenous abnormal connections between arteries and veins, resulting in a high flow, pulsating collections of
• Mixed - a combination of any of the other four types
Hemangiomas can be superficial or deep and most commonly have the following symptoms:
• Superficial hemangiomas appear as bright red, flat or raised patches on the skin
• Deep ones growing below the surface may not have an obvious outward appearance
• Both types are usually compressible to the touch
• They most often grow in the head or neck area, but they can involve any part of the body, including major organs
• Their size is variable and while most patients only have one lesion, multiple hemangiomas can occur
Vascular malformation symptoms are highly variable and depend on the type, size and location of the malformation. Symptoms may be absent altogether or life threatening if it’s an arteriovenous malformation (AVM).
Common arteriovenous vascular malformation symptoms include:
• Neurological problems, such as learning disorders, or ischemia, or lack of oxygen, which
can affect muscle control, vision, or speech.
We are grateful to have been ranked #1 on U.S. News & World Report's list of the best children's hospitals in the nation for the third year in a row, an honor we could not have achieved without the patients and families who inspire us to do our very best for them. Thanks to you, Boston Children's is a place where we can write the greatest children's stories ever told.”