Thalamic Astrocytoma and Hypothalamic Astrocytoma Pediatric Research and Clinical Trials

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Contact the Glioma Program

Dana-Farber/Boston Children's Cancer and Blood Disorders Center is one of nine institutions in the nation belonging to the Pediatric Oncology Therapeutic Experimental Investigators Consortium (POETIC), a collaborative clinical research group dedicated to the development of new and innovative treatments for children with all types of cancer and tumors. The consortium offers experimental therapies to patients with newly diagnosed tumors and with relapsed (returning) or refractory (resistant to treatment) disease.

Dana-Farber/Boston Children’s is also home to the Pediatric Low-Grade Astrocytoma (PLGA) Research Program, the world’s largest program dedicated to pediatric low-grade gliomas like thalamic/hypothalamic astrocytomas. The program conducts advanced research on the causes and treatment of low-grade gliomas.

Through the PLGA program, we have pioneered strategies for analyzing the genetic and molecular characteristics of pediatric low-grade astrocytomas, established a patient registry and multiple international research projects and initiated a number of phase II protocols using molecular inhibitors for children with progressive/recurrent low-grade gliomas. And, in collaboration with the Broad Institute of Harvard and Massachusetts Institute of Technology, we have made strides toward a better understanding of these conditions.

Clinical trials

For many children with brain tumors or other rare or hard-to-treat conditions, clinical trials provide new options.

We are grateful to have been ranked #1 on U.S. News & World Report's list of the best children's hospitals in the nation for the third year in a row, an honor we could not have achieved without the patients and families who inspire us to do our very best for them. Thanks to you, Boston Children's is a place where we can write the greatest children's stories ever told.”
- Sandra L. Fenwick, President and CEO

Boston Children's Hospital
300 Longwood Avenue, Boston, MA 02115
For Patients: 617-355-6000
For Referring Providers: 844-BCH-PEDS | 844-224-7337