Syndrome of Inappropriate Antidiuretic Hormone Secretion Symptoms & Causes

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In-Depth

What causes SIADH?

SIADH tends to occur in people with heart failure, or in people with a diseased hypothalamus (the part of the brain that works directly with the pituitary gland to produce hormones).

In other cases, a certain cancer (elsewhere in the body, often in the lungs) may produce the antidiuretic hormone. SIADH may also be caused by:

What are the symptoms of SIADH?

While each child may experience symptoms differently, in more severe cases of SIADH, symptoms may include:

  • nausea
  • vomiting
  • irritability
  • personality changes, such as combativeness, confusion, and hallucinations
  • seizures
  • stupor
  • coma

The symptoms of SIADH may resemble other problems or medical conditions.

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