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At Children’s Hospital Boston, we understand that you may have a lot of questions when your child is diagnosed with precocious puberty. How can I help my child feel less self-conscious about being different? How will early puberty affect my child long-term? Are there any serious side-effects to treatment? We’ve tried to provide some answers to those questions on this site and our doctors can explain your child’s condition to you fully. There are two types of precocious puberty: central precocious puberty (gonadotropin-dependent) is the most common, affecting more girls than boys. It’s triggered by the premature secretion of gonadotropins from the brain. peripheral precocious puberty (gonadotropin-independent) is not triggered by the early release of gonadotropin hormones in the brain, but by androgen and estrogen production from other parts of the body. What are gonadotropins? Gonadotropins are hormones released by the pituitary gland in the brain that are responsible for stimulating the gonads (ovaries and testes) to produce sex hormones. The sex hormones, in turn, cause sexual development and maturation. In other words, we can think of gonadotropins as the hormones that are ultimately responsible for puberty.
What causes central precocious puberty? In girls, the cause of precocious puberty 90 to 95 percent of the time is idiopathic, or unknown, meaning doctors don’t know for certain why it happens. Boys are more likely to have an underlying identifiable cause. Early puberty and sexual development may be caused by:
What causes peripheral precocious puberty? Peripheral precocious puberty may be caused by:
What are the signs of precocious puberty? Although each child may experience signs of precocious puberty differently, they are generally the same as the signs of regular puberty, including:
When your child is diagnosed with precocious puberty, you may feel overwhelmed with information. It can be easy to lose track of the questions that occur to you. Lots of parents find it helpful to jot down questions as they arise – that way, when you talk to your child’s doctors, you can be sure that all of your concerns are addressed. If your child is old enough, you may want to suggest that she write down what she wants to ask her health care provider, too. Here are some questions to get you started:
Q: What causes precocious puberty? A: In girls, in 90 to 95 percent of cases, the cause of precocious puberty is idiopathic, or unknown, meaning doctors don’t know for certain why it happens. An underlying cause is usually found in boys. Q: How is precocious puberty treated? A: The goal of treatment for precocious puberty is to stop, and possibly reverse, the onset of puberty. Treatment will also depend on the type of precocious puberty your child has and the underlying cause, if known. When treating central precocious puberty at Children’s Hospital Boston, we often use synthetic luteinizing-hormone-releasing hormone (LHRH). This hormone appears to stop sexual maturation brought on by the disorder by stopping the pituitary gland from releasing gonadotropin. Treatment of peripheral precocious puberty depends on the cause for the increase in estrogen or testosterone levels in the body. Q: How will precocious puberty affect my child? A: In addition to showing physical signs of early puberty, children with precocious puberty often have low self-esteem linked to the feeling of being different than their peers. Other people, including children and adults, may assume children with precocious puberty are older than they actually are and may expect them to behave beyond their maturity level. Encouraging your child to be open about her feelings will help immensely. Q: Will my child be OK? A: There’s every reason to be optimistic. With proper treatment and care, most children with precocious puberty will ultimately experience a normal and happy adolescence.
Coping and support?
Many parents ask, ‘How will early puberty affect my child emotionally?’ The short answer is that early puberty will cause your child's body to change much sooner than her peers’ bodies, and this sense of being different, coupled with the hormonal change-induced emotional mood swings, may make your child feel self-conscious. Your child may feel uncomfortable about these sexual changes as well. Helping your child cope with teasing from her peers is important, as is treating your child age-appropriately and taking steps to boost his or her self-esteem. At Children’s Hospital Boston, we know what you’re going through, and we’re here to help guide you through the process. We also have a number of other resources to help you and your family. Patient education From the first office visit, our physicians and nurses will be on hand to walk you through your child’s treatment and help answer any questions you may have. They will also reach out to you by phone, continuing the care and support you received while at Children’s. Parent to parent Want to talk with someone whose child has been treated for precocious puberty? We can often put you in touch with other families who have been through the same treatments that you and your child are facing, and share their experience. Social work and mental health professionals Our social workers and mental health clinicians have helped many other families in your situation. We can offer counseling and assistance with issues such as coping with your child’s diagnosis, stresses relating to coping with illness and dealing with financial difficulties. On our For Patients and Families site, you can read all you need to know about:
Treatment and care The goal of treatment for precocious puberty is to stop, and possibly reverse, the onset of your child’s early puberty. Treatment will also depend on the type of precocious puberty and the underlying cause, if it’s known. Treating central precocious puberty When treating children with central precocious puberty, we often use synthetic luteinizing-hormone-releasing hormone (LHRH). This hormone appears to stop sexual maturation brought on by the disorder by stopping the pituitary gland from releasing gonadotropin. LHRH can be given as an injection once per month or via a small implant placed surgically under the skin, which is effective for one year. Your child’s doctor will help determine which form of therapy would be more appropriate for your child. The duration of each child’s treatment varies and is determined individually, but children are usually treated until they reach an age at which progression through puberty would be appropriate. Once medication is stopped, children will progress through puberty normally, though the pace may be faster than average. Treatment for central precocious puberty has no known long-term side effects. Short-term side effects can include pain or irritation at injection sites or difficulties with medications given during implant insertion. Treating peripheral precocious puberty Treatment for peripheral precocious puberty depends on what’s causing excess estrogen or androgen production. Options include tumor removal, blocking the actions of estrogen or androgen on the body, or treatment of hypothyroidism with replacement thyroid hormone.
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