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The most common symptom of narcolepsy is excessive daytime sleepiness, especially when the person isn't active. Some people with narcolepsy may also have sleep attacks that last about 15-30 minutes and that can happen at any time.
About 60 percent of people with narcolepsy have a symptom called cataplexy — a sudden episode of muscle weakness while awake. Cataplexy is triggered by emotions, most often positive emotions, such as laughter. But it can also be triggered by negative emotions, such as anger and frustration. Cataplexy usually begins with muscle weakness in the face and neck and spreads to muscles of the body and limbs. In mild cases, it can cause a sagging face or slurred speech. In severe cases, it can cause the child to collapse to the ground, unable to move for a few minutes. Cataplexy usually only occurs in people with type 1 narcolepsy.
Other symptoms of narcolepsy can include:
Generally, people with type 1 narcolepsy (narcolepsy and cataplexy) have more severe symptoms.
The symptoms of narcolepsy most often start between ages 10 and 19. However, it’s becoming more common for children to be diagnosed before 10.
Type 1 narcolepsy is caused by a severe loss of a certain cluster of neurons (brain cells) that produce a neurochemical in the brain that helps maintain wakefulness. Less is known about the cause of narcolepsy type 2 (narcolepsy without cataplexy), but it may be caused by a less severe loss of these same neurons.
There is also a link between type 1 narcolepsy and certain infections, such as the flu, and vaccinations. This has led experts to believe that narcolepsy may be caused by an autoimmune process. Researchers are still learning more about the causes of narcolepsy.
We are grateful to have been ranked #1 on U.S. News & World Report's list of the best children's hospitals in the nation for the third year in a row, an honor we could not have achieved without the patients and families who inspire us to do our very best for them. Thanks to you, Boston Children's is a place where we can write the greatest children's stories ever told.”