Muscle weakness (hypotonia) Testing & Diagnosis

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Causes of muscle weakness

Your child's doctor will obtain a medical history for your family and your child and will perform a physical examination that will likely include a detailed muscle function and neurological examination. The latter, also called a neuro exam, may be performed with instruments, such as lights and reflex hammers, and usually does not cause any pain to the child.

•   assessment of motor and sensory skills
•   balance and coordination
•   mental status (the child's level of awareness and interaction with the environment)
•   reflexes 
•   functioning of the nerves

Diagnostic testing for muscle weakness

Depending on what your child's doctor suspects, the following tests may also be used to find out what's causing your child's muscle weakness:

•   Magnetic Resonance Imaging (MRI) – A diagnostic procedure that uses a combination of large magnets, radio
    frequencies and a computer to produce detailed images of organs and structures within the body. This test is
    done to rule out any associated abnormalities of the spinal cord and nerves
•   Computerized Tomography Scan (also called a CT or CAT scan) – A diagnostic imaging procedure that uses a
    combination of X-rays and computer technology to produce cross-sectional images (often called "slices"), both
    horizontally and vertically, of the body. A CT scan shows detailed images of any part of the body, including the
    bones, muscles, fat and organs. CT scans are more detailed than general X-rays
•   Blood tests
•   EMG (electromyogram) - a test used to evaluate nerve and muscle function
•   EEG (electroencephalogram) - a test that measures the electrical activity in the brain, called brain waves. An EEG
    measures brain waves through small button electrodes that are placed on your child's scalp
•   spinal tap - also called lumbar puncture, a spinal tap is done to measure the amount of pressure in the spinal canal
    and/or to remove a small amount of cerebral spinal fluid (CSF) for testing. Cerebral spinal fluid is the fluid that bathes
    your child's brain and spinal cord
•   karyotype - This test, a chromosomal analysis from a blood test, is used to determine whether the problem is the
    result of a genetic disorder
•   muscle biopsy: a sample of muscle tissue is removed and examined under a microscope
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