Hydronephrosis Pediatric Research and Clinical Trials

LIke ThisLIke ThisLIke ThisLIke ThisLIke This

Contact the Department of Urology

  • 1-617-355-7796

In addition to leading the way in the use of robotic surgery, Boston Children’s Hospital is always working toward more effective treatments for children with urologic disorders. Our urology department has been conducting several projects that hold great promise for improving the lives of children with hydronephrosis.     

Finding the genetic markers of vesicoureteral reflux (VUR): One of the more common causes of hydronephrosis, VUR has long been difficult for physicians to manage. In addition, it has often been frustrating for parents because there is currently no way to detect which children are at risk.

To diagnose VUR, physicians must pass a catheter up the urinary tract into the bladder. Our researchers aim to replace that procedure with a simple genetic test. They also hope to offer a way to predict which children have VUR that will not resolve on its own.

Using proteins to target kidney obstruction: A team led by Richard Lee, MD, is studying proteins in the urine to identify illnesses at an earlier age. Specifically, the team hopes to be able to predict risk for VUR. Another goal is to detect changes in the bladder tissue that may tell whether a child’s hydronephrosis is getting worse.

Hydrophrenosis

We are grateful to have been ranked #1 on U.S. News & World Report's list of the best children's hospitals in the nation for the third year in a row, an honor we could not have achieved without the patients and families who inspire us to do our very best for them. Thanks to you, Boston Children's is a place where we can write the greatest children's stories ever told.”
- Sandra L. Fenwick, President and CEO

Boston Children's Hospital 300 Longwood Avenue, Boston, MA 02115 617-355-6000 | 800-355-7944

Close