Hemolytic Disease | Diagnosis & Treatment

How is hemolytic disease of the newborn diagnosed?

Hemolytic disease of the newborn (HDN) can be diagnosed during pregnancy or after the baby is born.

Tests conducted during pregnancy may include:

  • complete blood count test for the mother
  • ultrasound
  • amniocentesis
  • cordocentesis

After birth, tests may include:

  • complete blood count test for the baby
  • umbilical cord blood test

What are the treatments for HDN?

Hemolytic disease of the newborn can be treated during pregnancy or after the baby is born. Treatment during pregnancy may include:

  • blood transfusion
  • early delivery of the baby if severe complications arise and baby's lungs are mature

After birth, treatment may include:

  • blood transfusion
  • intravenous fluids
  • oxygen or mechanical breathing machine
  • exchange transfusion to replace the baby's damaged blood with fresh blood