Conditions + Treatments

Hemolytic Disease of the Newborn

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Contact the Blood Disorders Center

Hemolytic disease of the newborn (HDN) – also called erythroblastosis fetalis – is a blood disorder that occurs when the blood types of a mother and baby are incompatible. The most common cause of HDN is Rh incompatibility. Our Blood Disorders Center provides comprehensive treatment and management of HDN.

  • HDN is relatively uncommon, affecting approximately 4,000 babies a year in the United States.
  • It is more likely to occur during a mother’s second or subsequent pregnancy.
  • There are two causes, Rh incompatibility and ABO incompatibility.
  • HDN due to Rh incompatibility occurs more frequently.
  • HDN can be treated during pregnancy or after the baby is born.
  • It is very preventable.

Our patients with Hemolytic disease of the newborn (HDN) are treated through the Blood Disorders Center at Dana-Farber/Boston Children's Cancer and Blood Disorders Center, an integrated pediatric hematology and oncology partnership between Dana-Farber Cancer Institute and Boston Children’s Hospital.

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Boston Children's Hospital 300 Longwood Avenue, Boston, MA 02115 617-355-6000 | 800-355-7944