Generalized Anxiety Disorder (GAD) Pediatric Research and Clinical Trials

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At Boston Children’s Hospital, we’re dedicated to proving the effectiveness of our treatment approaches through rigorous scientific testing. Our research program is one of the largest and most active of any pediatric hospital in the world.

Each day, our psychiatry and psychology researchers are working toward important discoveries to propel new advances in preventing, diagnosing and treating mental and behavioral disorders. This research reinforces our ongoing commitment to enhancing mental health care for all children and adolescents. 

Our research projects with potential implications for treating anxiety include:

Michelle Bosquet Enlow, PhD, a developmental and clinical psychologist at Boston Children’s Hospital, has a particular interest in understanding risk factors for anxiety. Her research examines the impact of maternal and child stress and trauma exposures and maternal psychopathology (depression, anxiety, posttraumatic stress disorder) on child development.

Baruch Krauss, MD ,attending physician in Boston Children’s Hospital Division of Emergency Medicine, is studying non-pharmacological strategies for managing acute procedural anxiety and pain in children.

David Clapham, chief of Boston Children’s Basic Cardiology Research Laboratories, along with a team of collaborators, has discovered a molecular “on-off” switch for innate fear (the fear that is embedded in our genes). This breakthrough could potentially lead to more effective anti-anxiety drugs.

David DeMaso, MD, Boston Children’s psychiatrist-in-chief, is exploring the use of new media technologies to help physically ill children cope with—and communicate—their feelings of worry and stress. 

Jennifer LeBovidge, PhD, and her colleagues in Boston Children’s Hospital Immunology Program are conducting a study of a group approach to treating children with food allergies. They aim to determine how best to help these children and their parents manage their allergies and cope with related feelings of anxiety.

Boston Children’s is so much more than a hospital—it’s a community of researchers, clinicians, administrators, support staff, innovators, teachers, patients and families, all working together to make the impossible possible. ”
- Sandra L. Fenwick, President and CEO

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