Glioblastoma multiforme in Children

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A high-grade glioma is a malignant tumor that arises from the brain’s glial cells, which nourish and support neurons. There are two high-grade gliomas: glioblastoma multiforme (grade IV glioma) and anaplastic astrocytoma (grade III glioma). These are aggressive tumors that rapidly infiltrate adjacent healthy brain tissue and, as a result, are difficult to treat.

As you read on, you’ll find detailed information about glioblastoma multiforme and anaplastic astrocytoma. If you would like to read more general information about brain tumors first, see our overview on brain tumors.

How Dana-Farber/Boston Children’s Cancer and Blood Disorders Center approaches glioblastoma multiforme and anaplastic astrocytoma

Your child will be seen by specialists and caregivers at Dana-Farber/Boston Children’s Cancer and Blood Disorders Center, an integrated pediatric oncology program through Dana-Farber Cancer Institute and Boston Children’s Hospital that provides—in one specialized program—all the services of both a leading cancer center and a leading pediatric hospital. Dana-Farber/Boston Children’s is a world-renowned destination for children with malignant and non-malignant brain and spinal cord tumors.

Most children diagnosed with glioblastoma multiforme or anaplastic astrocytoma receive surgery and radiation, and in some cases chemotherapy. Our pediatric neuro-oncology and pediatric neurosurgical specialists at Dana-Farber/Boston Children’s Pediatric Brain Tumor Center offer:

  • technological advances, such as the intra-operative MRI, which allow our pediatric neurosurgeons to “see” the tumor as they operate with MRI scans
  • treatment with the best standard of care, including neurosurgery, radiation therapy and chemotherapy
  • access to unique Phase I clinical trials
We are grateful to have been ranked #1 on U.S. News & World Report's list of the best children's hospitals in the nation for the third year in a row, an honor we could not have achieved without the patients and families who inspire us to do our very best for them. Thanks to you, Boston Children's is a place where we can write the greatest children's stories ever told.”
- Sandra L. Fenwick, President and CEO

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